MX2007010769A - Compuestos de quinolina como agonistas de receptor 5-ht4. - Google Patents
Compuestos de quinolina como agonistas de receptor 5-ht4.Info
- Publication number
- MX2007010769A MX2007010769A MX2007010769A MX2007010769A MX2007010769A MX 2007010769 A MX2007010769 A MX 2007010769A MX 2007010769 A MX2007010769 A MX 2007010769A MX 2007010769 A MX2007010769 A MX 2007010769A MX 2007010769 A MX2007010769 A MX 2007010769A
- Authority
- MX
- Mexico
- Prior art keywords
- compounds
- receptor agonists
- quinolinone compounds
- quinolinone
- receptor
- Prior art date
Links
- 108091005482 5-HT4 receptors Proteins 0.000 title abstract 3
- 239000000018 receptor agonist Substances 0.000 title abstract 2
- 229940044601 receptor agonist Drugs 0.000 title abstract 2
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical class C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65800705P | 2005-03-02 | 2005-03-02 | |
| PCT/US2006/007284 WO2006094063A1 (en) | 2005-03-02 | 2006-03-01 | Quinolinone compounds as 5-ht4 receptor agonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2007010769A true MX2007010769A (es) | 2008-03-07 |
Family
ID=36588769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007010769A MX2007010769A (es) | 2005-03-02 | 2006-03-01 | Compuestos de quinolina como agonistas de receptor 5-ht4. |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US7446114B2 (enExample) |
| EP (1) | EP1871772B1 (enExample) |
| JP (1) | JP5042043B2 (enExample) |
| KR (1) | KR20070107807A (enExample) |
| CN (1) | CN101163701A (enExample) |
| AU (1) | AU2006218603A1 (enExample) |
| BR (1) | BRPI0608392A2 (enExample) |
| CA (1) | CA2599404A1 (enExample) |
| EA (1) | EA013567B1 (enExample) |
| ES (1) | ES2523851T3 (enExample) |
| IL (1) | IL185407A0 (enExample) |
| MX (1) | MX2007010769A (enExample) |
| NO (1) | NO20074884L (enExample) |
| NZ (1) | NZ560828A (enExample) |
| WO (1) | WO2006094063A1 (enExample) |
| ZA (1) | ZA200707142B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI351282B (en) | 2004-04-07 | 2011-11-01 | Theravance Inc | Quinolinone-carboxamide compounds as 5-ht4 recepto |
| TWI377206B (en) * | 2005-04-06 | 2012-11-21 | Theravance Inc | Crystalline form of a quinolinone-carboxamide compound |
| MY143574A (en) * | 2005-11-22 | 2011-05-31 | Theravance Inc | Carbamate compounds as 5-ht4 receptor agonists |
| GB0525068D0 (en) | 2005-12-08 | 2006-01-18 | Novartis Ag | Organic compounds |
| WO2008102720A1 (ja) * | 2007-02-19 | 2008-08-28 | Kaneka Corporation | 光学活性３－アミノピペリジン又はその塩の製造方法 |
| ES2578628T3 (es) * | 2009-09-14 | 2016-07-28 | Suven Life Sciences Limited | Compuestos de L-dihidro-2-oxoquinolina como ligandos del receptor de 5-HT4 |
| RU2017134794A (ru) * | 2015-04-02 | 2019-04-04 | ТЕРЕВАНС БАЙОФАРМА Ар энд Ди АйПи, ЭлЭлСи | Комбинированная лекарственная форма антагониста мю-опиоидного рецептора и опиоидного средства |
| JP7664491B2 (ja) | 2022-01-11 | 2025-04-17 | スヴェン・ライフ・サイエンシーズ・リミテッド | ５－ＨＴ４受容体アゴニストとしてのピロロ［１，２－ｂ］－２－ピリダジノン化合物 |
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| TWI351282B (en) | 2004-04-07 | 2011-11-01 | Theravance Inc | Quinolinone-carboxamide compounds as 5-ht4 recepto |
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| US7737163B2 (en) | 2004-06-15 | 2010-06-15 | Pfizer Inc. | Benzimidazolone carboxylic acid derivatives |
| ATE441646T1 (de) | 2004-11-05 | 2009-09-15 | Theravance Inc | 5-ht4-rezeptoragonistenverbindungen |
| ATE431824T1 (de) | 2004-11-05 | 2009-06-15 | Theravance Inc | Chinolinon-carboxamid-verbindungen |
| WO2006069125A1 (en) | 2004-12-22 | 2006-06-29 | Theravance, Inc. | Indazole-carboxamide compounds |
| ATE495171T1 (de) | 2005-06-07 | 2011-01-15 | Theravance Inc | Benzimidazoloncarbonsäureamidverbindungen als agonisten des 5-ht4-rezeptors |
| MY143574A (en) | 2005-11-22 | 2011-05-31 | Theravance Inc | Carbamate compounds as 5-ht4 receptor agonists |
-
2006
- 2006-03-01 WO PCT/US2006/007284 patent/WO2006094063A1/en not_active Ceased
- 2006-03-01 CA CA002599404A patent/CA2599404A1/en not_active Abandoned
- 2006-03-01 AU AU2006218603A patent/AU2006218603A1/en not_active Abandoned
- 2006-03-01 MX MX2007010769A patent/MX2007010769A/es active IP Right Grant
- 2006-03-01 NZ NZ560828A patent/NZ560828A/en not_active IP Right Cessation
- 2006-03-01 ES ES06736578.3T patent/ES2523851T3/es active Active
- 2006-03-01 JP JP2007558181A patent/JP5042043B2/ja not_active Expired - Fee Related
- 2006-03-01 CN CNA2006800131887A patent/CN101163701A/zh active Pending
- 2006-03-01 KR KR1020077022429A patent/KR20070107807A/ko not_active Ceased
- 2006-03-01 US US11/365,320 patent/US7446114B2/en active Active
- 2006-03-01 EA EA200701867A patent/EA013567B1/ru not_active IP Right Cessation
- 2006-03-01 EP EP06736578.3A patent/EP1871772B1/en active Active
- 2006-03-01 BR BRPI0608392-7A patent/BRPI0608392A2/pt not_active IP Right Cessation
-
2007
- 2007-08-21 IL IL185407A patent/IL185407A0/en unknown
- 2007-08-23 ZA ZA200707142A patent/ZA200707142B/xx unknown
- 2007-09-25 NO NO20074884A patent/NO20074884L/no not_active Application Discontinuation
-
2008
- 2008-09-22 US US12/234,906 patent/US7875629B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006094063A1 (en) | 2006-09-08 |
| BRPI0608392A2 (pt) | 2009-12-29 |
| AU2006218603A1 (en) | 2006-09-08 |
| ZA200707142B (en) | 2008-10-29 |
| JP5042043B2 (ja) | 2012-10-03 |
| EA200701867A1 (ru) | 2008-02-28 |
| EA013567B1 (ru) | 2010-06-30 |
| JP2008531711A (ja) | 2008-08-14 |
| US20060199839A1 (en) | 2006-09-07 |
| EP1871772A1 (en) | 2008-01-02 |
| ES2523851T3 (es) | 2014-12-02 |
| NO20074884L (no) | 2007-11-29 |
| US7446114B2 (en) | 2008-11-04 |
| US7875629B2 (en) | 2011-01-25 |
| IL185407A0 (en) | 2008-01-06 |
| KR20070107807A (ko) | 2007-11-07 |
| US20090036483A1 (en) | 2009-02-05 |
| CN101163701A (zh) | 2008-04-16 |
| NZ560828A (en) | 2011-01-28 |
| CA2599404A1 (en) | 2006-09-08 |
| EP1871772B1 (en) | 2014-09-10 |
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