MEP43508A - Oral administration form for difficulty soluble basic active ingredients which are applied orally - Google Patents

Oral administration form for difficulty soluble basic active ingredients which are applied orally

Info

Publication number
MEP43508A
MEP43508A MEP-435/08A MEP43508A MEP43508A ME P43508 A MEP43508 A ME P43508A ME P43508 A MEP43508 A ME P43508A ME P43508 A MEP43508 A ME P43508A
Authority
ME
Montenegro
Prior art keywords
oral administration
active ingredients
administration form
soluble basic
applied orally
Prior art date
Application number
MEP-435/08A
Other languages
Bosnian (bs)
English (en)
Inventor
Ulrich Brauns
Rolf-Stefan Brickl
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of MEP43508A publication Critical patent/MEP43508A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MEP-435/08A 2002-03-07 2003-03-04 Oral administration form for difficulty soluble basic active ingredients which are applied orally MEP43508A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10209982A DE10209982A1 (de) 2002-03-07 2002-03-07 Oral zu applizierende Darreichungsform für schwerlösliche basische Wirkstoffe
YU77904A RS77904A (en) 2002-03-07 2003-03-04 Oral administration form for difficulty soluble basic active ingredients which are applied orally
PCT/EP2003/002184 WO2003074032A1 (fr) 2002-03-07 2003-03-04 Forme d'administration orale pour principes actifs basiques difficilement solubles

Publications (1)

Publication Number Publication Date
MEP43508A true MEP43508A (en) 2011-02-10

Family

ID=27771069

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-435/08A MEP43508A (en) 2002-03-07 2003-03-04 Oral administration form for difficulty soluble basic active ingredients which are applied orally

Country Status (10)

Country Link
US (1) US20050095293A1 (fr)
EP (2) EP1499298A1 (fr)
JP (1) JP2005526738A (fr)
AU (1) AU2003229555A1 (fr)
BR (1) BR0308188A (fr)
DE (1) DE10209982A1 (fr)
ME (1) MEP43508A (fr)
NO (1) NO20043998L (fr)
RS (1) RS77904A (fr)
WO (1) WO2003074032A1 (fr)

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US20040048877A1 (en) * 2002-05-22 2004-03-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions containing flibanserin
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DE102004011512B4 (de) * 2004-03-08 2022-01-13 Boehringer Ingelheim Vetmedica Gmbh Pharmazeutische Zubereitung enthaltend Pimobendan
US8980894B2 (en) 2004-03-25 2015-03-17 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
EP1579862A1 (fr) 2004-03-25 2005-09-28 Boehringer Ingelheim Vetmedica Gmbh Utilisation des inhibiteurs de PDE III pour la réduction de la taille du coeur chez des mammifères souffrant d'insufficances cardiaques
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PL1912650T3 (pl) 2005-08-03 2018-01-31 Sprout Pharmaceuticals Inc Zastosowanie flibanseryny w leczeniu otyłości
HU227490B1 (en) * 2005-08-26 2011-07-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag Sustained release pharmaceutical preparation containing carvedilol
WO2007048803A1 (fr) 2005-10-29 2007-05-03 Boehringer Ingelheim International Gmbh Derives de benzimidazolone utiles pour le traitement des troubles premenstruels et d'autres troubles sexuels chez la femme
US20070105869A1 (en) * 2005-11-08 2007-05-10 Stephane Pollentier Use of flibanserin for the treatment of pre-menopausal sexual desire disorders
JP4572300B2 (ja) * 2006-01-19 2010-11-04 トーアエイヨー株式会社 ピモベンダン経口投与製剤
EP1976492B8 (fr) † 2006-01-27 2018-07-04 Adare Pharmaceuticals, Inc. Système d'administration de médicaments comprenant des médicaments faiblement basiques et des acides organiques
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US20090312242A1 (en) * 2006-06-30 2009-12-17 Ramiro Castro Flibanserin for the treatment of urinary incontinence and related diseases
EP2043648A1 (fr) * 2006-07-14 2009-04-08 Boehringer Ingelheim International GmbH Utilisation de flibansérine pour le traitement de troubles sexuels chez les femmes
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TW200914006A (en) 2007-07-12 2009-04-01 Takeda Pharmaceutical Coated preparation
UY31335A1 (es) * 2007-09-12 2009-04-30 Tratamiento de sintomas vasomotores
DE102008004893A1 (de) 2008-01-17 2009-07-23 Add Technologies Ltd. Trägerpellets, Verfahren zu deren Herstellung und deren Verwendung
EP2090297A1 (fr) * 2008-02-13 2009-08-19 Boehringer Ingelheim International GmbH Formules de flibanserine
FR2934156B1 (fr) * 2008-07-23 2010-09-24 Virbac Medicament appetissant a administration orale sous forme solide
WO2010055119A2 (fr) * 2008-11-17 2010-05-20 Novartis Ag Composition pharmaceutique comprenant du pimobendane
AU2010302419B2 (en) * 2009-09-30 2014-07-31 Merck Sharp & Dohme (Uk) Limited Formulations for c-Met kinase inhibitors
US20120040008A1 (en) * 2010-08-11 2012-02-16 Ashish Chatterji Pharmaceutical compositions of metabotropic glutamate 5 receptor (mglu5) antagonists
US20120039999A1 (en) * 2010-08-11 2012-02-16 Ashish Chatterji Pharmaceutical compositions of metabotropic glutamate 5 receptor (mglu5) antagonists
JP2015500853A (ja) * 2011-12-22 2015-01-08 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 即時放出マルチユニットペレットシステム
EP2825159B1 (fr) 2012-03-15 2022-06-22 Boehringer Ingelheim Vetmedica GmbH Formulation de comprimé pharmaceutique pour le secteur médical vétérinaire, son procédé de production et d'utilisation
EP2834224B1 (fr) 2012-04-02 2018-06-06 MSN Laboratories Limited Procédés de préparation de dérivés de benzimidazole et de sels de ceux-ci
US20130345262A1 (en) 2012-06-25 2013-12-26 Boehringer Ingelheim International Gmbh Method for prevention of stroke
BR112015005489B1 (pt) 2012-09-19 2022-07-12 Taiho Pharmaceutical Co., Ltd. Composição farmacêutica para administração oral com dissolução e/ou absorção aperfeiçoadas
WO2015007760A1 (fr) 2013-07-19 2015-01-22 Boehringer Ingelheim Vetmedica Gmbh Composition pharmaceutique aqueuse liquide contenant des dérivés de cyclodextrine éthérifiés conservés
EP3106150B1 (fr) 2013-12-04 2021-07-28 Boehringer Ingelheim Vetmedica GmbH Compositions pharmaceutiques améliorées de pimobendane
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Also Published As

Publication number Publication date
AU2003229555A1 (en) 2003-09-16
EP1818047A2 (fr) 2007-08-15
RS77904A (en) 2006-10-27
WO2003074032A1 (fr) 2003-09-12
JP2005526738A (ja) 2005-09-08
US20050095293A1 (en) 2005-05-05
DE10209982A1 (de) 2003-09-25
EP1818047A3 (fr) 2008-08-06
EP1499298A1 (fr) 2005-01-26
BR0308188A (pt) 2004-12-21
NO20043998L (no) 2004-10-05

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