ME03560B - MOLEKULI ANTI-GCC ANTITELA l NJIHOVA UPOTREBA U ISPITIVANJU OSETLJIVOSTI NA GCC-CILJANU TERAPIJU - Google Patents

MOLEKULI ANTI-GCC ANTITELA l NJIHOVA UPOTREBA U ISPITIVANJU OSETLJIVOSTI NA GCC-CILJANU TERAPIJU

Info

Publication number
ME03560B
ME03560B MEP-2019-257A MEP2019257A ME03560B ME 03560 B ME03560 B ME 03560B ME P2019257 A MEP2019257 A ME P2019257A ME 03560 B ME03560 B ME 03560B
Authority
ME
Montenegro
Prior art keywords
gcc
susceptibility
test
same
antibody molecules
Prior art date
Application number
MEP-2019-257A
Other languages
German (de)
English (en)
French (fr)
Unknown language (me)
Inventor
Helen Alison Frank
Alice A Mcdonald
Theresa L O'keefe
Original Assignee
Millennium Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49477498&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ME03560(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc
Publication of ME03560B publication Critical patent/ME03560B/me

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/5759Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/988Lyases (4.), e.g. aldolases, heparinase, enolases, fumarase

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Psychology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
MEP-2019-257A 2012-04-27 2013-04-27 MOLEKULI ANTI-GCC ANTITELA l NJIHOVA UPOTREBA U ISPITIVANJU OSETLJIVOSTI NA GCC-CILJANU TERAPIJU ME03560B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261639376P 2012-04-27 2012-04-27
EP13782061.9A EP2841575B1 (en) 2012-04-27 2013-04-27 Anti-gcc antibody molecules and use of same to test for susceptibility to gcc-targeted therapy
PCT/US2013/038542 WO2013163633A1 (en) 2012-04-27 2013-04-27 Anti-gcc antibody molecules and use of same to test for susceptibility to gcc-targeted therapy

Publications (1)

Publication Number Publication Date
ME03560B true ME03560B (me) 2020-07-20

Family

ID=49477498

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2019-257A ME03560B (me) 2012-04-27 2013-04-27 MOLEKULI ANTI-GCC ANTITELA l NJIHOVA UPOTREBA U ISPITIVANJU OSETLJIVOSTI NA GCC-CILJANU TERAPIJU

Country Status (41)

Country Link
US (3) US9000129B2 (https=)
EP (1) EP2841575B1 (https=)
JP (2) JP6472746B2 (https=)
KR (1) KR102046435B1 (https=)
CN (1) CN104395470B (https=)
AR (1) AR090884A1 (https=)
AU (1) AU2013251312B2 (https=)
CA (1) CA2871614C (https=)
CL (1) CL2014002911A1 (https=)
CO (1) CO7280144A2 (https=)
CR (1) CR20140497A (https=)
CY (1) CY1122557T1 (https=)
DK (1) DK2841575T3 (https=)
DO (1) DOP2014000242A (https=)
EA (1) EA034689B1 (https=)
EC (1) ECSP14028523A (https=)
ES (1) ES2749181T3 (https=)
GE (1) GEP201706737B (https=)
HR (1) HRP20191690T1 (https=)
HU (1) HUE046404T2 (https=)
IL (1) IL235307B (https=)
LT (1) LT2841575T (https=)
MA (1) MA37569B1 (https=)
ME (1) ME03560B (https=)
MX (1) MX362020B (https=)
MY (1) MY188442A (https=)
NZ (1) NZ701601A (https=)
PE (1) PE20142322A1 (https=)
PH (1) PH12014502399B1 (https=)
PL (1) PL2841575T3 (https=)
PT (1) PT2841575T (https=)
RS (1) RS59370B1 (https=)
SA (1) SA113340502B1 (https=)
SG (1) SG11201406855TA (https=)
SI (1) SI2841575T1 (https=)
SM (1) SMT201900536T1 (https=)
TN (1) TN2014000454A1 (https=)
TW (1) TWI631137B (https=)
UA (1) UA117910C2 (https=)
WO (1) WO2013163633A1 (https=)
ZA (1) ZA201407723B (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201407757XA (en) 2009-10-23 2015-01-29 Millennium Pharm Inc Anti-gcc antibody molecules and related compositions and methods
US20160264663A1 (en) * 2013-10-21 2016-09-15 The Centre For Drug Research And Development Anti-podocalyxin antibodies and methods of using the same
AU2015218355B2 (en) 2014-02-14 2019-09-12 Arkansas Children's Hospital Research Institute, Inc. Acetaminophen protein adducts and methods of use thereof
EP3227681B1 (en) 2014-12-03 2020-10-21 Bioventures, LLC Anti-acetaminophen antibodies and acetaminophen protein adducts
US11090383B2 (en) 2015-10-01 2021-08-17 Centre For Drug Research And Development Anti-podocalyxin antibodies and methods of using the same
US11473081B2 (en) * 2016-12-12 2022-10-18 xCella Biosciences, Inc. Methods and systems for screening using microcapillary arrays
KR102080887B1 (ko) * 2017-11-07 2020-02-24 고려대학교 산학협력단 Gcc2 유전자 또는 단백질을 과발현하는 엑소좀 기반 폐암 진단 또는 예후 예측용 마커 조성물
JP7197584B2 (ja) * 2017-12-06 2022-12-27 ベンタナ メディカル システムズ, インコーポレイテッド デジタル病理学分析結果の格納および読み出し方法
US11568657B2 (en) 2017-12-06 2023-01-31 Ventana Medical Systems, Inc. Method of storing and retrieving digital pathology analysis results
FI3846788T3 (fi) * 2018-09-05 2025-12-17 Univ Amsterdam Pde11-estäjiä parkinsonin taudin hoitoon
WO2021205325A1 (en) * 2020-04-08 2021-10-14 Pfizer Inc. Anti-gucy2c antibodies and uses thereof
CN115605594A (zh) * 2020-06-02 2023-01-13 帝人制药株式会社(Jp) 抗igf-1受体人源化抗体
WO2022127871A1 (en) * 2020-12-17 2022-06-23 Parasol Biotech Ltd. Gucy2c binding molecules and uses thereof
CN116964100A (zh) * 2021-04-07 2023-10-27 株式会社Lg化学 Gucy2c结合多肽及其用途
EP4594364A1 (en) * 2022-09-28 2025-08-06 Legend Biotech Ireland Limited Antibody and chimeric antigen receptors targeting gcc and methods of use thereof
KR20250099224A (ko) 2022-11-01 2025-07-01 하이델베르크 파마 리서치 게엠베하 항-gucy2c 항체 및 이의 용도
CN116535514B (zh) * 2023-06-15 2024-02-02 上海斯丹赛生物技术有限公司 抗鸟苷酸环化酶c抗体及其在癌症治疗中的应用
CN117069848B (zh) * 2023-08-02 2025-02-28 武汉爱博泰克生物科技有限公司 抗人cd146兔单克隆抗体及其应用
CN121866270A (zh) * 2023-09-21 2026-04-14 南京传奇生物科技有限公司 抗gcc抗体、嵌合抗原受体及其用途
EP4566631A1 (en) 2023-12-06 2025-06-11 Heidelberg Pharma Research GmbH New antibody drug conjugate as well as methods of production and uses thereof
CN120965861B (zh) * 2025-10-22 2026-02-13 杭州博茵生物技术有限公司 一种Fc效应消除的新型骨架流式抗体及其制备方法与应用

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5237051A (en) 1990-12-06 1993-08-17 Vanderbilt University Purified enterotoxin receptor protein
US7097839B1 (en) 1993-10-26 2006-08-29 Thomas Jefferson University ST receptor binding compounds and methods of using the same
US5518888A (en) 1993-10-26 1996-05-21 Thomas Jefferson University ST receptor binding compounds and methods of using the same
US5879656A (en) 1993-10-26 1999-03-09 Thomas Jefferson University Methods of treating metastatic colorectal cancer with ST receptor binding compounds
EP0734264B1 (en) 1993-10-26 2004-02-18 Thomas Jefferson University Compositions that specifically bind to colorectal cancer cells and methods of using the same
US5601990A (en) 1994-09-13 1997-02-11 Thomas Jefferson University Methods of diagnosing colorectal tumors and metastasis thereof
US6455251B1 (en) 1994-09-13 2002-09-24 Thomas Jefferson University Methods of and kits and compositions for diagnosing colorectal tumors and metastasis thereof
DE69723580T2 (de) 1996-05-03 2004-06-03 Thomas Jefferson University Impfstoff gegen metastasierenden kolorektalkrebs.
US6602659B1 (en) 1996-05-03 2003-08-05 Thomas Jefferson University Methods of and kits and compositions for diagnosing colorectal tumors and metastasis thereof
US6120995A (en) 1997-08-07 2000-09-19 Thomas Jefferson University Compositions that specifically bind to colorectal cancer cells and methods of using the same
US6696550B2 (en) 1998-07-23 2004-02-24 Millennium Pharmaceuticals, Inc. Humanized anti-CCR2 antibodies and methods of use therefor
US8092514B1 (en) 1998-11-16 2012-01-10 Boston Scientific Scimed, Inc. Stretchable anti-buckling coiled-sheet stent
US20040031072A1 (en) 1999-05-06 2004-02-12 La Rosa Thomas J. Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement
CA2404431C (en) 2000-03-27 2011-06-07 Thomas Jefferson University Guanylyl cyclase c in the detection of stomach and esophageal cancers
PE20020574A1 (es) 2000-12-06 2002-07-02 Wyeth Corp Anticuerpos humanizados que reconocen el peptido amiloideo beta
PT1377314E (pt) 2001-01-26 2012-01-02 Inhibitex Inc Anticorpos monoclonais para a proteína clfa e método de utilização no tratamento ou prevenção de infecções
CA2905585C (en) 2001-03-29 2020-02-18 Bausch Health Ireland Limited Guanylate cyclase receptor agonists for the treatment and/or prevention of cancer or polyps
DE60236735D1 (de) 2001-04-13 2010-07-29 Biogen Idec Inc Antikörper gegen vla-1
EP1470146B8 (en) 2001-12-28 2007-09-12 Amgen Fremont Inc. Antibodies against the muc18 antigen
US20040110933A1 (en) 2002-09-13 2004-06-10 Dyax Corporation CD44-binding ligands
DE10254601A1 (de) 2002-11-22 2004-06-03 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
US7371727B2 (en) 2003-01-28 2008-05-13 Microbia, Inc. Methods and compositions for the treatment of gastrointestinal disorders
US7304036B2 (en) 2003-01-28 2007-12-04 Microbia, Inc. Methods and compositions for the treatment of gastrointestinal disorders
US8206704B2 (en) 2003-02-10 2012-06-26 Thomas Jefferson University Use of GCC ligands
US20090005257A1 (en) 2003-05-14 2009-01-01 Jespers Laurent S Process for Recovering Polypeptides that Unfold Reversibly from a Polypeptide Repertoire
US7871610B2 (en) 2003-08-12 2011-01-18 Dyax Corp. Antibodies to Tie1 ectodomain
EP1781339B1 (en) 2004-06-25 2013-12-25 Thomas Jefferson University Guanylyl cyclase C ligands
ZA200705695B (en) 2004-12-21 2009-02-25 Astrazeneca Ab Antibodies directed to angiopoietin-2 and uses thereof
AR056857A1 (es) 2005-12-30 2007-10-24 U3 Pharma Ag Anticuerpos dirigidos hacia her-3 (receptor del factor de crecimiento epidérmico humano-3) y sus usos
MX354786B (es) 2007-06-04 2018-03-21 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
AU2008287128B2 (en) * 2007-08-10 2013-07-18 Janssen Biotech, Inc. Immunoglobulin cleavage fragments as disease indicators and compositions for detecting and binding such
MX2010001395A (es) 2007-08-10 2010-03-10 Regeneron Pharma Anticuerpos humanos de alta afinidad de factor de crecimiento de nervio humano.
CA2705792A1 (en) * 2007-11-30 2009-06-11 Milan Radovich Vegf polymorphisms and anti-angiogenesis therapy
US20110195415A1 (en) 2008-05-13 2011-08-11 Thomas Jefferson University Guanylyl cyclase c qrt-pcr
WO2009149278A1 (en) 2008-06-04 2009-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
AU2009270833B2 (en) 2008-07-16 2015-02-19 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
WO2010065293A1 (en) 2008-12-03 2010-06-10 Boehringer Ingelheim Pharmaceuticals Inc. Antibodies for guanylyl cyclase receptors
EP3266795A1 (en) * 2009-02-12 2018-01-10 Cell Signaling Technology, Inc. Method for detecting a fig-ros fusion polynucleotide
JP2012518389A (ja) 2009-02-25 2012-08-16 ダイアグノキュア インコーポレイテッド Gi癌の転移を検出するための方法
US8598188B2 (en) * 2009-03-12 2013-12-03 Kinki University Method for predicting therapeutic efficacy of chemotherapy on non-small-cell lung cancer
CA2801729A1 (en) 2009-06-15 2010-12-23 Thomas Jefferson University Compositions for and methods of activating guanylyl cyclase c
WO2011066048A1 (en) 2009-10-22 2011-06-03 Thomas Jefferson University Cell-based anti-cancer compositions and methods of making and using the same
SG10201407757XA (en) * 2009-10-23 2015-01-29 Millennium Pharm Inc Anti-gcc antibody molecules and related compositions and methods
EP2576622A4 (en) * 2010-06-01 2013-11-27 Univ Monash ON THE UNPROCESSED RECEPTOR TYROSINE KINASE C-MET TARGETED ANTIBODIES
BR112013001879A2 (pt) * 2010-08-13 2019-09-03 F. Hoffmann-La Roche Ag "método para aprefeiçoar o efeito de tratamento em um paciente que sofre de câncer gástrico, método in vitro, kit, uso de um olignucleotídeo ou polipetídio e uso de bevacizumabe"
US20150086481A1 (en) 2011-07-28 2015-03-26 Memorial Sloan-Kettering Cancer Center Diagnosis and treatment of parkinson's disease
US9156915B2 (en) 2012-04-26 2015-10-13 Thomas Jefferson University Anti-GCC antibody molecules
EP2961424A4 (en) * 2013-02-28 2016-10-19 Millennium Pharm Inc ADMINISTRATION OF AN ANTI-GCC-ANTIBODY-ACTIVE CONJUGATE AND A DNA DAMAGING ACTIVE IN THE TREATMENT OF CANCER

Also Published As

Publication number Publication date
JP6472746B2 (ja) 2019-02-20
US20160130344A1 (en) 2016-05-12
BR112014026742A2 (pt) 2017-07-11
SG11201406855TA (en) 2014-11-27
CN104395470A (zh) 2015-03-04
HRP20191690T1 (hr) 2019-12-27
CO7280144A2 (es) 2015-05-29
PH12014502399A1 (en) 2014-12-22
AU2013251312B2 (en) 2018-03-22
US9273146B1 (en) 2016-03-01
ES2749181T3 (es) 2020-03-19
US9000129B2 (en) 2015-04-07
ECSP14028523A (es) 2015-09-30
AU2013251312A1 (en) 2014-10-30
KR20150004882A (ko) 2015-01-13
EA201491977A1 (ru) 2015-04-30
CN104395470B (zh) 2018-02-06
DOP2014000242A (es) 2014-11-30
CR20140497A (es) 2015-02-10
EP2841575A1 (en) 2015-03-04
JP6517267B2 (ja) 2019-05-22
GEP201706737B (en) 2017-09-25
JP2015516985A (ja) 2015-06-18
KR102046435B1 (ko) 2019-11-19
JP2017131245A (ja) 2017-08-03
DK2841575T3 (da) 2019-09-23
EP2841575A4 (en) 2016-06-15
EA034689B1 (ru) 2020-03-06
IL235307B (en) 2019-07-31
TWI631137B (zh) 2018-08-01
US20130287783A1 (en) 2013-10-31
PH12014502399B1 (en) 2022-04-22
PL2841575T3 (pl) 2020-01-31
WO2013163633A1 (en) 2013-10-31
PE20142322A1 (es) 2015-01-25
NZ701601A (en) 2016-09-30
SMT201900536T1 (it) 2019-11-13
HK1208049A1 (en) 2016-02-19
MX362020B (es) 2019-01-04
MX2014013081A (es) 2015-01-12
SA113340502B1 (ar) 2015-09-17
TN2014000454A1 (en) 2016-03-30
CA2871614A1 (en) 2013-10-31
CY1122557T1 (el) 2021-01-27
UA117910C2 (uk) 2018-10-25
IL235307A0 (en) 2014-12-31
PT2841575T (pt) 2019-10-11
ZA201407723B (en) 2019-01-30
EP2841575B1 (en) 2019-06-26
HUE046404T2 (hu) 2020-02-28
MA37569B1 (fr) 2020-08-31
TW201348258A (zh) 2013-12-01
CL2014002911A1 (es) 2015-01-30
MY188442A (en) 2021-12-09
LT2841575T (lt) 2019-10-10
RS59370B1 (sr) 2019-11-29
SI2841575T1 (sl) 2019-11-29
AR090884A1 (es) 2014-12-10
CA2871614C (en) 2021-08-31

Similar Documents

Publication Publication Date Title
ZA201407723B (en) Anti-gcc antibody molecules and use of same to test for susceptibility to gcc-targeted therapy
ZA201409224B (en) Cd33 antibodies and use of same to treat cancer
ZA201501858B (en) Anti-mcam antibodies and associated methods of use
ZA201406967B (en) Anti sez6 antibodies and methods of use
IL236738B (en) Human antibodies to gfra3 and methods of using them
ZA201404675B (en) Anti-lrp5 antibodies and methods of use
LT2806892T (lt) Kombinuota terapija, panaudojant antikūnus ir endoglikozidazes
ZA201405864B (en) Cd47 antibodies and methods of use thereof
SG11201502757QA (en) Anti-c16orf54 antibodies and methods of use thereof
LT2922850T (lt) Junginiai ir jų panaudojimo būdai
ZA201503403B (en) Anti-hemagglutinin antibodies and methods of use
EP2874650A4 (en) FOR CD22 SPECIFIC ANTIBODIES AND METHOD FOR USE THEREOF
PL2869837T3 (pl) Przeciwciała przeciw teofilinie i sposoby ich stosowania
EP2919643A4 (en) METHOD AND SYSTEMS FOR QUANTITATIVE MEASUREMENT OF MENTAL CONDITIONS
GB2521356B (en) Antibodies for use in treating conditions related to specific PCKS9 variants and associated diagnostic methods
GB201215352D0 (en) Improvements in and relating to the anaalysis of sample