MD4629B1 - Metode de tratament a fibrozei şi cancerului - Google Patents
Metode de tratament a fibrozei şi canceruluiInfo
- Publication number
- MD4629B1 MD4629B1 MDA20150076A MD20150076A MD4629B1 MD 4629 B1 MD4629 B1 MD 4629B1 MD A20150076 A MDA20150076 A MD A20150076A MD 20150076 A MD20150076 A MD 20150076A MD 4629 B1 MD4629 B1 MD 4629B1
- Authority
- MD
- Moldova
- Prior art keywords
- cancers
- fibrosis
- treatment
- methods
- carboxydimethylmethyloxyphenyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Invenţia se referă la medicină, şi anume la utilizarea compusului 1-[4-metiltiofenil]-3-[3,5-dimetil-4-carboxidimetilmetiloxifenil]prop-2-en-1-onă pentru tratamentul bolilor fibrotice şi cancerului.Secvenţe: 20
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13305067 | 2013-01-18 | ||
| PCT/EP2014/051060 WO2014111584A1 (en) | 2013-01-18 | 2014-01-20 | Methods of treatment of fibrosis and cancers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD20150076A2 MD20150076A2 (ro) | 2015-11-30 |
| MD4629B1 true MD4629B1 (ro) | 2019-05-31 |
Family
ID=47628079
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDA20150076A MD4629B1 (ro) | 2013-01-18 | 2014-01-20 | Metode de tratament a fibrozei şi cancerului |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US20150352065A1 (ro) |
| EP (1) | EP2948137B1 (ro) |
| JP (1) | JP6218854B2 (ro) |
| KR (1) | KR102196277B1 (ro) |
| CN (1) | CN105120855B (ro) |
| AU (1) | AU2014206781B2 (ro) |
| CA (1) | CA2897258C (ro) |
| CY (1) | CY1121156T1 (ro) |
| DK (1) | DK2948137T3 (ro) |
| EA (1) | EA031718B1 (ro) |
| ES (1) | ES2702038T3 (ro) |
| HK (1) | HK1214773A1 (ro) |
| HU (1) | HUE042569T2 (ro) |
| IL (1) | IL239715B (ro) |
| LT (1) | LT2948137T (ro) |
| MD (1) | MD4629B1 (ro) |
| MX (1) | MX361565B (ro) |
| NZ (1) | NZ709420A (ro) |
| PH (1) | PH12015501566B1 (ro) |
| PL (1) | PL2948137T3 (ro) |
| PT (1) | PT2948137T (ro) |
| SG (1) | SG11201505281PA (ro) |
| SI (1) | SI2948137T1 (ro) |
| TR (1) | TR201819042T4 (ro) |
| WO (1) | WO2014111584A1 (ro) |
| ZA (1) | ZA201505151B (ro) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT2948137T (lt) | 2013-01-18 | 2018-12-27 | Genfit | Fibrozės ir vėžio gydymo būdai |
| US11162097B2 (en) * | 2016-02-23 | 2021-11-02 | Nogra Pharma Limited | Methods of treating intestinal fibrosis using SMAD7 inhibition |
| CA3057940A1 (en) * | 2017-04-18 | 2018-10-25 | Genfit | Combination of elafibranor or derivatives thereof with an anti-nash, anti-fibrotic or anti-cholestatic agent |
| EP3830070A1 (en) | 2018-08-03 | 2021-06-09 | Genfit | Elafibranor salts |
| GB201901507D0 (en) * | 2019-02-04 | 2019-03-27 | St Georges Hospital Medical School | New treatment |
| US20230094109A1 (en) | 2020-02-10 | 2023-03-30 | Genfit | Polymorphs of elafibranor |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7736677B2 (en) * | 2001-06-20 | 2010-06-15 | Metaproteomics, Llc | Xanthohumol and tetrahydro-isoalpha acid based protein kinase modulation cancer treatment |
| FR2841900B1 (fr) * | 2002-07-08 | 2007-03-02 | Genfit S A | Nouveaux derives de 1,3-diphenylprop-2-en-1-one substitues, preparation et utilisations |
| FR2841784B1 (fr) * | 2002-07-08 | 2007-03-02 | Composition a base de derives de 1,3-diphenylprop-2en-1-one substitues, preparation et utilisations | |
| FR2857361B1 (fr) * | 2003-07-08 | 2005-09-09 | Genfit S A | PREPARATION DE DERIVES DE 1,3-DIPHENYPROP-2-¼n-1-one |
| ES2681794T3 (es) * | 2009-11-26 | 2018-09-17 | Genfit | Uso de derivados de 1,3-difenilprop-2-en-1-ona para tratar trastornos hepáticos |
| ES2384060B1 (es) * | 2010-03-24 | 2013-09-23 | Lipotec S.A. | Cápsulas de nanopartículas lipídicas. |
| LT2948137T (lt) | 2013-01-18 | 2018-12-27 | Genfit | Fibrozės ir vėžio gydymo būdai |
-
2014
- 2014-01-20 LT LTEP14702771.8T patent/LT2948137T/lt unknown
- 2014-01-20 ES ES14702771T patent/ES2702038T3/es active Active
- 2014-01-20 AU AU2014206781A patent/AU2014206781B2/en active Active
- 2014-01-20 TR TR2018/19042T patent/TR201819042T4/tr unknown
- 2014-01-20 MD MDA20150076A patent/MD4629B1/ro not_active IP Right Cessation
- 2014-01-20 EP EP14702771.8A patent/EP2948137B1/en active Active
- 2014-01-20 SI SI201431009T patent/SI2948137T1/sl unknown
- 2014-01-20 PL PL14702771T patent/PL2948137T3/pl unknown
- 2014-01-20 SG SG11201505281PA patent/SG11201505281PA/en unknown
- 2014-01-20 CA CA2897258A patent/CA2897258C/en active Active
- 2014-01-20 DK DK14702771.8T patent/DK2948137T3/en active
- 2014-01-20 MX MX2015009251A patent/MX361565B/es active IP Right Grant
- 2014-01-20 JP JP2015553119A patent/JP6218854B2/ja active Active
- 2014-01-20 EA EA201591345A patent/EA031718B1/ru not_active IP Right Cessation
- 2014-01-20 KR KR1020157021736A patent/KR102196277B1/ko active IP Right Grant
- 2014-01-20 NZ NZ709420A patent/NZ709420A/en unknown
- 2014-01-20 HU HUE14702771A patent/HUE042569T2/hu unknown
- 2014-01-20 PT PT14702771T patent/PT2948137T/pt unknown
- 2014-01-20 CN CN201480005335.0A patent/CN105120855B/zh active Active
- 2014-01-20 WO PCT/EP2014/051060 patent/WO2014111584A1/en active Application Filing
- 2014-01-20 US US14/760,880 patent/US20150352065A1/en not_active Abandoned
-
2015
- 2015-06-30 IL IL239715A patent/IL239715B/en active IP Right Grant
- 2015-07-14 PH PH12015501566A patent/PH12015501566B1/en unknown
- 2015-07-17 ZA ZA2015/05151A patent/ZA201505151B/en unknown
-
2016
- 2016-03-11 HK HK16102854.3A patent/HK1214773A1/zh unknown
-
2017
- 2017-05-04 US US15/586,456 patent/US10792277B2/en active Active
-
2018
- 2018-12-14 CY CY20181101346T patent/CY1121156T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC9A | Refusal of application (patent for invention) | ||
| KA4A | Patent for invention lapsed due to non-payment of fees (with right of restoration) |