PT2948137T - Métodos de tratamento de fibrose e de cancro - Google Patents

Métodos de tratamento de fibrose e de cancro

Info

Publication number
PT2948137T
PT2948137T PT14702771T PT14702771T PT2948137T PT 2948137 T PT2948137 T PT 2948137T PT 14702771 T PT14702771 T PT 14702771T PT 14702771 T PT14702771 T PT 14702771T PT 2948137 T PT2948137 T PT 2948137T
Authority
PT
Portugal
Prior art keywords
fibrosis
cancers
treatment
methods
Prior art date
Application number
PT14702771T
Other languages
English (en)
Inventor
Hum Dean
Hanf Rémy
Walczak Robert
Noel Benoit
Original Assignee
Genfit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genfit filed Critical Genfit
Publication of PT2948137T publication Critical patent/PT2948137T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT14702771T 2013-01-18 2014-01-20 Métodos de tratamento de fibrose e de cancro PT2948137T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13305067 2013-01-18

Publications (1)

Publication Number Publication Date
PT2948137T true PT2948137T (pt) 2018-12-20

Family

ID=47628079

Family Applications (1)

Application Number Title Priority Date Filing Date
PT14702771T PT2948137T (pt) 2013-01-18 2014-01-20 Métodos de tratamento de fibrose e de cancro

Country Status (26)

Country Link
US (2) US20150352065A1 (pt)
EP (1) EP2948137B1 (pt)
JP (1) JP6218854B2 (pt)
KR (1) KR102196277B1 (pt)
CN (1) CN105120855B (pt)
AU (1) AU2014206781B2 (pt)
CA (1) CA2897258C (pt)
CY (1) CY1121156T1 (pt)
DK (1) DK2948137T3 (pt)
EA (1) EA031718B1 (pt)
ES (1) ES2702038T3 (pt)
HK (1) HK1214773A1 (pt)
HU (1) HUE042569T2 (pt)
IL (1) IL239715B (pt)
LT (1) LT2948137T (pt)
MD (1) MD4629B1 (pt)
MX (1) MX361565B (pt)
NZ (1) NZ709420A (pt)
PH (1) PH12015501566B1 (pt)
PL (1) PL2948137T3 (pt)
PT (1) PT2948137T (pt)
SG (1) SG11201505281PA (pt)
SI (1) SI2948137T1 (pt)
TR (1) TR201819042T4 (pt)
WO (1) WO2014111584A1 (pt)
ZA (1) ZA201505151B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT2948137T (lt) 2013-01-18 2018-12-27 Genfit Fibrozės ir vėžio gydymo būdai
US11162097B2 (en) * 2016-02-23 2021-11-02 Nogra Pharma Limited Methods of treating intestinal fibrosis using SMAD7 inhibition
CA3057940A1 (en) * 2017-04-18 2018-10-25 Genfit Combination of elafibranor or derivatives thereof with an anti-nash, anti-fibrotic or anti-cholestatic agent
EP3830070A1 (en) 2018-08-03 2021-06-09 Genfit Elafibranor salts
GB201901507D0 (en) * 2019-02-04 2019-03-27 St Georges Hospital Medical School New treatment
US20230094109A1 (en) 2020-02-10 2023-03-30 Genfit Polymorphs of elafibranor

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7736677B2 (en) * 2001-06-20 2010-06-15 Metaproteomics, Llc Xanthohumol and tetrahydro-isoalpha acid based protein kinase modulation cancer treatment
FR2841900B1 (fr) * 2002-07-08 2007-03-02 Genfit S A Nouveaux derives de 1,3-diphenylprop-2-en-1-one substitues, preparation et utilisations
FR2841784B1 (fr) * 2002-07-08 2007-03-02 Composition a base de derives de 1,3-diphenylprop-2en-1-one substitues, preparation et utilisations
FR2857361B1 (fr) * 2003-07-08 2005-09-09 Genfit S A PREPARATION DE DERIVES DE 1,3-DIPHENYPROP-2-¼n-1-one
ES2681794T3 (es) * 2009-11-26 2018-09-17 Genfit Uso de derivados de 1,3-difenilprop-2-en-1-ona para tratar trastornos hepáticos
ES2384060B1 (es) * 2010-03-24 2013-09-23 Lipotec S.A. Cápsulas de nanopartículas lipídicas.
LT2948137T (lt) 2013-01-18 2018-12-27 Genfit Fibrozės ir vėžio gydymo būdai

Also Published As

Publication number Publication date
US20150352065A1 (en) 2015-12-10
PL2948137T3 (pl) 2019-02-28
US10792277B2 (en) 2020-10-06
MX2015009251A (es) 2015-10-15
MX361565B (es) 2018-12-11
TR201819042T4 (tr) 2019-01-21
CA2897258A1 (en) 2014-07-24
ZA201505151B (en) 2016-07-27
AU2014206781A1 (en) 2015-07-16
EA201591345A1 (ru) 2015-11-30
SI2948137T1 (sl) 2019-01-31
MD20150076A2 (ro) 2015-11-30
HUE042569T2 (hu) 2019-07-29
US20170239213A1 (en) 2017-08-24
KR20150114497A (ko) 2015-10-12
CN105120855B (zh) 2019-05-07
EA031718B1 (ru) 2019-02-28
EP2948137B1 (en) 2018-11-14
PH12015501566A1 (en) 2015-09-21
CY1121156T1 (el) 2020-05-29
IL239715A0 (en) 2015-08-31
AU2014206781B2 (en) 2018-08-23
NZ709420A (en) 2020-04-24
KR102196277B1 (ko) 2020-12-29
LT2948137T (lt) 2018-12-27
HK1214773A1 (zh) 2016-08-05
CA2897258C (en) 2021-02-02
SG11201505281PA (en) 2015-08-28
EP2948137A1 (en) 2015-12-02
JP2016506913A (ja) 2016-03-07
IL239715B (en) 2019-06-30
WO2014111584A1 (en) 2014-07-24
PH12015501566B1 (en) 2015-09-21
JP6218854B2 (ja) 2017-10-25
MD4629B1 (ro) 2019-05-31
DK2948137T3 (en) 2019-01-07
CN105120855A (zh) 2015-12-02
ES2702038T3 (es) 2019-02-27

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