MD3493849T2 - Utilizare noua a N,N-bis-2-mercaptoetil izoftalamidă - Google Patents

Utilizare noua a N,N-bis-2-mercaptoetil izoftalamidă

Info

Publication number
MD3493849T2
MD3493849T2 MDE20190671T MDE20190671T MD3493849T2 MD 3493849 T2 MD3493849 T2 MD 3493849T2 MD E20190671 T MDE20190671 T MD E20190671T MD E20190671 T MDE20190671 T MD E20190671T MD 3493849 T2 MD3493849 T2 MD 3493849T2
Authority
MD
Moldova
Prior art keywords
paracetamol
nbmi
toxicity
pharmaceutically acceptable
administration
Prior art date
Application number
MDE20190671T
Other languages
English (en)
Romanian (ro)
Inventor
Boyd Eugene Haley
Ragnar Axel Theodor Klingberg
Original Assignee
Emeramed Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emeramed Ltd filed Critical Emeramed Ltd
Publication of MD3493849T2 publication Critical patent/MD3493849T2/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MDE20190671T 2016-08-05 2017-08-04 Utilizare noua a N,N-bis-2-mercaptoetil izoftalamidă MD3493849T2 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB201613535 2016-08-05
PCT/GB2017/052306 WO2018025049A1 (en) 2016-08-05 2017-08-04 New use of n,n-bis-2-mercaptoethyl isophthalamide

Publications (1)

Publication Number Publication Date
MD3493849T2 true MD3493849T2 (ro) 2022-04-30

Family

ID=60202272

Family Applications (1)

Application Number Title Priority Date Filing Date
MDE20190671T MD3493849T2 (ro) 2016-08-05 2017-08-04 Utilizare noua a N,N-bis-2-mercaptoetil izoftalamidă

Country Status (30)

Country Link
US (2) US20190240173A1 (cg-RX-API-DMAC10.html)
EP (2) EP4029497A1 (cg-RX-API-DMAC10.html)
JP (1) JP6926192B2 (cg-RX-API-DMAC10.html)
KR (1) KR102538388B1 (cg-RX-API-DMAC10.html)
CN (2) CN121926911A (cg-RX-API-DMAC10.html)
AU (1) AU2017305661B2 (cg-RX-API-DMAC10.html)
BR (1) BR112019002130A2 (cg-RX-API-DMAC10.html)
CL (1) CL2019000229A1 (cg-RX-API-DMAC10.html)
CY (1) CY1125039T1 (cg-RX-API-DMAC10.html)
DK (1) DK3493849T3 (cg-RX-API-DMAC10.html)
EA (1) EA201990443A1 (cg-RX-API-DMAC10.html)
ES (1) ES2907838T3 (cg-RX-API-DMAC10.html)
HR (1) HRP20220252T1 (cg-RX-API-DMAC10.html)
HU (1) HUE057782T2 (cg-RX-API-DMAC10.html)
IL (1) IL264538B2 (cg-RX-API-DMAC10.html)
LT (1) LT3493849T (cg-RX-API-DMAC10.html)
MA (1) MA45855B1 (cg-RX-API-DMAC10.html)
MD (1) MD3493849T2 (cg-RX-API-DMAC10.html)
MX (1) MX387853B (cg-RX-API-DMAC10.html)
MY (1) MY199733A (cg-RX-API-DMAC10.html)
PH (1) PH12019500237A1 (cg-RX-API-DMAC10.html)
PL (1) PL3493849T3 (cg-RX-API-DMAC10.html)
PT (1) PT3493849T (cg-RX-API-DMAC10.html)
RS (1) RS62924B1 (cg-RX-API-DMAC10.html)
SG (1) SG11201900565RA (cg-RX-API-DMAC10.html)
SI (1) SI3493849T1 (cg-RX-API-DMAC10.html)
SM (1) SMT202200109T1 (cg-RX-API-DMAC10.html)
UA (1) UA125394C2 (cg-RX-API-DMAC10.html)
WO (1) WO2018025049A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201900594B (cg-RX-API-DMAC10.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202005057D0 (en) 2020-04-06 2020-05-20 Emeramed Ltd New Use
WO2026037909A1 (en) * 2024-08-16 2026-02-19 Emeramed Limited N,n-bis-2-mercaptoethyl isophthalamide for use in the treatment of pain

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586600B2 (en) 2000-12-06 2003-07-01 University Of Kentucky Research Foundation Multidentate sulfur-containing ligands
US8950583B2 (en) * 2008-12-06 2015-02-10 Ermes Medical Company Limited Method to remove heavy metals from a mammal
US20120122787A1 (en) * 2009-07-10 2012-05-17 Rong Li Methods for treating polycystic kidney disease (pkd) or other cyst forming diseases
JP2013505963A (ja) 2009-09-28 2013-02-21 ユニヴァーシティ オブ ケンタッキー リサーチ ファウンデイション 汚染された環境から元素を除去するチオール含有化合物およびその使用方法
US8575218B2 (en) 2009-09-28 2013-11-05 The University Of Kentucky Research Foundation Thiol-containing compounds for the removal of elements from tissues and formulations therefor
US20110237776A1 (en) 2010-03-25 2011-09-29 Haley Boyd E Aromatic compounds with sulfur containing ligands
US8426368B2 (en) 2010-03-25 2013-04-23 The University Of Kentucky Research Foundation Method of ameliorating oxidative stress and supplementing the diet

Also Published As

Publication number Publication date
KR102538388B1 (ko) 2023-05-30
EA201990443A1 (ru) 2019-07-31
JP2019524782A (ja) 2019-09-05
PT3493849T (pt) 2022-02-23
EP3493849B1 (en) 2021-12-01
SMT202200109T1 (it) 2022-05-12
BR112019002130A2 (pt) 2019-05-14
KR20190035724A (ko) 2019-04-03
RS62924B1 (sr) 2022-03-31
PL3493849T3 (pl) 2022-03-28
MY199733A (en) 2023-11-21
WO2018025049A1 (en) 2018-02-08
SI3493849T1 (sl) 2022-04-29
MX2019000978A (es) 2019-06-10
MA45855B1 (fr) 2022-02-28
JP6926192B2 (ja) 2021-08-25
IL264538B2 (en) 2023-02-01
PH12019500237A1 (en) 2019-10-28
CN109562179A (zh) 2019-04-02
CL2019000229A1 (es) 2019-04-26
EP4029497A1 (en) 2022-07-20
US20250325503A1 (en) 2025-10-23
IL264538B (en) 2022-10-01
MA45855A (fr) 2021-03-17
IL264538A (cg-RX-API-DMAC10.html) 2019-03-31
CA3032858A1 (en) 2018-02-08
LT3493849T (lt) 2022-03-10
DK3493849T3 (en) 2022-03-07
HUE057782T2 (hu) 2022-06-28
CY1125039T1 (el) 2023-03-24
AU2017305661A1 (en) 2019-02-14
US20190240173A1 (en) 2019-08-08
UA125394C2 (uk) 2022-03-02
CN121926911A (zh) 2026-04-28
MX387853B (es) 2025-03-19
NZ750271A (en) 2025-07-25
ES2907838T3 (es) 2022-04-26
HRP20220252T1 (hr) 2022-04-29
AU2017305661B2 (en) 2023-05-18
SG11201900565RA (en) 2019-02-27
ZA201900594B (en) 2019-08-28
EP3493849A1 (en) 2019-06-12

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