MD3377108T2 - Procedeu de obţinere a unei formulări de pulbere uscată ce conţine un anticolinergic, un corticosteroid și un beta-adrenergic - Google Patents
Procedeu de obţinere a unei formulări de pulbere uscată ce conţine un anticolinergic, un corticosteroid și un beta-adrenergicInfo
- Publication number
- MD3377108T2 MD3377108T2 MDE20180917T MDE20180917T MD3377108T2 MD 3377108 T2 MD3377108 T2 MD 3377108T2 MD E20180917 T MDE20180917 T MD E20180917T MD E20180917 T MDE20180917 T MD E20180917T MD 3377108 T2 MD3377108 T2 MD 3377108T2
- Authority
- MD
- Moldova
- Prior art keywords
- dry powder
- anticholinergic
- adrenergic
- powder formulation
- corticosteroid
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
Invenţia se referă la o formulare sub formă de pulbere pentru administrare prin inhalare cu ajutorul unui inhalator cu pulbere uscată, în special, invenţia se referă la un procedeu pentru prepararea unei formulări sub formă de pulbere uscată care cuprinde o combinaţie dintre un anticolinergic, un agonist beta2-adrenergic şi un corticosteroid inhalator.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15194660 | 2015-11-16 | ||
PCT/EP2016/077558 WO2017085004A1 (en) | 2015-11-16 | 2016-11-14 | A process for preparing a dry powder formulation comprising an anticholinergic, a corticosteroid and a beta-adrenergic |
Publications (1)
Publication Number | Publication Date |
---|---|
MD3377108T2 true MD3377108T2 (ro) | 2020-07-31 |
Family
ID=54548062
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MDE20200899T MD3620176T2 (ro) | 2015-11-16 | 2016-11-14 | Procedeu pentru prepararea unei formulări sub formă de pulbere uscată care cuprinde un anticolinergic, un corticosteroid și un beta-adrenergic |
MDE20200898T MD3628331T2 (ro) | 2015-11-16 | 2016-11-14 | Procedeu de preparare unei formulări sub formă de pulbere uscată care cuprinde un anticolinergic, un corticosteroid și un beta-adrenergic |
MDE20180917T MD3377108T2 (ro) | 2015-11-16 | 2016-11-14 | Procedeu de obţinere a unei formulări de pulbere uscată ce conţine un anticolinergic, un corticosteroid și un beta-adrenergic |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MDE20200899T MD3620176T2 (ro) | 2015-11-16 | 2016-11-14 | Procedeu pentru prepararea unei formulări sub formă de pulbere uscată care cuprinde un anticolinergic, un corticosteroid și un beta-adrenergic |
MDE20200898T MD3628331T2 (ro) | 2015-11-16 | 2016-11-14 | Procedeu de preparare unei formulări sub formă de pulbere uscată care cuprinde un anticolinergic, un corticosteroid și un beta-adrenergic |
Country Status (36)
Country | Link |
---|---|
US (4) | US10086004B2 (ro) |
EP (3) | EP3628331B1 (ro) |
JP (1) | JP6963548B2 (ro) |
KR (1) | KR20180082443A (ro) |
CN (1) | CN108289962B (ro) |
AR (1) | AR106688A1 (ro) |
AU (1) | AU2016356858B2 (ro) |
CA (1) | CA3005290A1 (ro) |
CL (1) | CL2018001298A1 (ro) |
CO (1) | CO2018005141A2 (ro) |
CY (3) | CY1123042T1 (ro) |
DK (3) | DK3628331T3 (ro) |
EA (1) | EA037716B1 (ro) |
ES (3) | ES2895687T3 (ro) |
GE (1) | GEP20207157B (ro) |
HR (3) | HRP20211598T1 (ro) |
HU (3) | HUE056260T2 (ro) |
IL (1) | IL259329B (ro) |
LT (3) | LT3377108T (ro) |
MA (3) | MA50488B1 (ro) |
MD (3) | MD3620176T2 (ro) |
ME (1) | ME03778B (ro) |
MX (1) | MX2018005977A (ro) |
MY (1) | MY186229A (ro) |
PE (1) | PE20181488A1 (ro) |
PH (1) | PH12018501022A1 (ro) |
PL (3) | PL3628331T3 (ro) |
PT (3) | PT3620176T (ro) |
RS (3) | RS62506B1 (ro) |
SA (1) | SA518391570B1 (ro) |
SG (2) | SG10201912093YA (ro) |
SI (3) | SI3620176T1 (ro) |
TW (1) | TWI731891B (ro) |
UA (1) | UA125019C2 (ro) |
WO (1) | WO2017085004A1 (ro) |
ZA (1) | ZA201803168B (ro) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3621589B1 (en) | 2017-05-11 | 2021-07-07 | Chiesi Farmaceutici S.p.A. | A process for preparing a dry powder formulation comprising an anticholinergic, a corticosteroid and a beta-adrenergic |
BR112019023378A2 (pt) * | 2017-05-11 | 2020-06-16 | Chiesi Farmaceutici S.P.A. | Processo para preparar uma formulação em pó para inalação para uso em um inalador de pó seco |
US11433063B1 (en) | 2019-03-12 | 2022-09-06 | Belhaven Biopharma, Inc. | Intranasal composition of pharmaceutical countermeasures for chemical warfare nerve agents and accidental exposure to organophosphate pesticides |
EP3947338A4 (en) * | 2019-03-27 | 2023-01-04 | Kemin Industries, Inc. | PROCESS FOR THE PREPARATION OF METAL CARBOXYLATES IN A ONE-POT REACTION |
CN112137957B (zh) * | 2019-06-26 | 2022-07-29 | 长风药业股份有限公司 | 一种药用吸入气雾剂及其制备方法 |
WO2021143785A1 (zh) * | 2020-01-15 | 2021-07-22 | 四川海思科制药有限公司 | 一种含茚达特罗的吸入气雾剂药物组合物及其制备方法 |
WO2022045995A1 (en) * | 2020-08-28 | 2022-03-03 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | A process for the preparation of dry powder compositions for inhalation |
US20220304894A1 (en) * | 2021-03-24 | 2022-09-29 | Cmpd Licensing, Llc | Drug powderization within vials |
CN118414147A (zh) | 2021-12-21 | 2024-07-30 | 凯西制药公司 | 填充在具有改善的耐湿性的吸入器中的干粉制剂 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PE20011227A1 (es) * | 2000-04-17 | 2002-01-07 | Chiesi Farma Spa | Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros |
GB0015043D0 (en) | 2000-06-21 | 2000-08-09 | Glaxo Group Ltd | Medicament dispenser |
PT1658872E (pt) | 2002-07-31 | 2011-05-12 | Chiesi Farma Spa | Inalador de p? |
CN102665679B (zh) | 2009-12-23 | 2014-11-26 | 奇斯药制品公司 | 用于copd的联合治疗 |
PE20151216A1 (es) * | 2012-12-06 | 2015-09-08 | Chiesi Farma Spa | Compuestos con actividad antagonista de los receptores muscarinicos y actividad agonista del receptor beta2 adrenergico |
PL2928890T3 (pl) * | 2012-12-06 | 2018-07-31 | Chiesi Farmaceutici S.P.A. | Związki wykazujące aktywność antagonisty receptorów muskarynowych i agonisty receptorów beta 2 adrenergicznych |
US9393202B2 (en) | 2013-04-26 | 2016-07-19 | Chiesi Farmaceutici S.P.A | Particle size reduction of an antimuscarinic compound |
WO2015004243A1 (en) * | 2013-07-11 | 2015-01-15 | Chiesi Farmaceutici S.P.A. | Dry powder formulation comprising an anticholinergic, a corticosteroid and a beta-adrenergic for administration by inhalation |
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2016
- 2016-11-14 PT PT192059806T patent/PT3620176T/pt unknown
- 2016-11-14 HR HRP20211598TT patent/HRP20211598T1/hr unknown
- 2016-11-14 MD MDE20200899T patent/MD3620176T2/ro unknown
- 2016-11-14 AR ARP160103473A patent/AR106688A1/es unknown
- 2016-11-14 PE PE2018000973A patent/PE20181488A1/es unknown
- 2016-11-14 LT LTEP16801982.6T patent/LT3377108T/lt unknown
- 2016-11-14 DK DK19205936.8T patent/DK3628331T3/da active
- 2016-11-14 PL PL19205936T patent/PL3628331T3/pl unknown
- 2016-11-14 KR KR1020187013286A patent/KR20180082443A/ko unknown
- 2016-11-14 CA CA3005290A patent/CA3005290A1/en active Pending
- 2016-11-14 LT LTEP19205980.6T patent/LT3620176T/lt unknown
- 2016-11-14 ES ES19205936T patent/ES2895687T3/es active Active
- 2016-11-14 PT PT168019826T patent/PT3377108T/pt unknown
- 2016-11-14 SI SI201631331T patent/SI3620176T1/sl unknown
- 2016-11-14 PL PL16801982T patent/PL3377108T3/pl unknown
- 2016-11-14 EP EP19205936.8A patent/EP3628331B1/en active Active
- 2016-11-14 ME MEP-2020-80A patent/ME03778B/me unknown
- 2016-11-14 MA MA50488A patent/MA50488B1/fr unknown
- 2016-11-14 GE GEAP201614783A patent/GEP20207157B/en unknown
- 2016-11-14 EA EA201890966A patent/EA037716B1/ru unknown
- 2016-11-14 SI SI201631349T patent/SI3628331T1/sl unknown
- 2016-11-14 MA MA50487A patent/MA50487B1/fr unknown
- 2016-11-14 RS RS20211283A patent/RS62506B1/sr unknown
- 2016-11-14 DK DK19205980.6T patent/DK3620176T3/da active
- 2016-11-14 EP EP16801982.6A patent/EP3377108B1/en active Active
- 2016-11-14 EP EP19205980.6A patent/EP3620176B1/en active Active
- 2016-11-14 RS RS20211196A patent/RS62404B1/sr unknown
- 2016-11-14 UA UAA201805271A patent/UA125019C2/uk unknown
- 2016-11-14 WO PCT/EP2016/077558 patent/WO2017085004A1/en active Application Filing
- 2016-11-14 DK DK16801982.6T patent/DK3377108T3/da active
- 2016-11-14 AU AU2016356858A patent/AU2016356858B2/en active Active
- 2016-11-14 RS RS20200440A patent/RS60171B1/sr unknown
- 2016-11-14 ES ES16801982T patent/ES2783855T3/es active Active
- 2016-11-14 PT PT192059368T patent/PT3628331T/pt unknown
- 2016-11-14 MD MDE20200898T patent/MD3628331T2/ro unknown
- 2016-11-14 HU HUE19205936A patent/HUE056260T2/hu unknown
- 2016-11-14 MY MYPI2018000704A patent/MY186229A/en unknown
- 2016-11-14 SI SI201630682T patent/SI3377108T1/sl unknown
- 2016-11-14 CN CN201680066801.5A patent/CN108289962B/zh active Active
- 2016-11-14 HU HUE19205980A patent/HUE056441T2/hu unknown
- 2016-11-14 TW TW105137048A patent/TWI731891B/zh active
- 2016-11-14 SG SG10201912093YA patent/SG10201912093YA/en unknown
- 2016-11-14 MX MX2018005977A patent/MX2018005977A/es unknown
- 2016-11-14 PL PL19205980T patent/PL3620176T3/pl unknown
- 2016-11-14 LT LTEP19205936.8T patent/LT3628331T/lt unknown
- 2016-11-14 JP JP2018524832A patent/JP6963548B2/ja active Active
- 2016-11-14 ES ES19205980T patent/ES2891073T3/es active Active
- 2016-11-14 SG SG11201804050QA patent/SG11201804050QA/en unknown
- 2016-11-14 HR HRP20211600TT patent/HRP20211600T1/hr unknown
- 2016-11-14 MA MA43256A patent/MA43256B1/fr unknown
- 2016-11-14 MD MDE20180917T patent/MD3377108T2/ro unknown
- 2016-11-14 HU HUE16801982A patent/HUE049751T2/hu unknown
- 2016-11-15 US US15/351,562 patent/US10086004B2/en active Active
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2018
- 2018-05-14 IL IL259329A patent/IL259329B/en active IP Right Grant
- 2018-05-14 CL CL2018001298A patent/CL2018001298A1/es unknown
- 2018-05-14 SA SA518391570A patent/SA518391570B1/ar unknown
- 2018-05-14 ZA ZA2018/03168A patent/ZA201803168B/en unknown
- 2018-05-15 PH PH12018501022A patent/PH12018501022A1/en unknown
- 2018-05-16 CO CONC2018/0005141A patent/CO2018005141A2/es unknown
- 2018-08-27 US US16/113,026 patent/US10772896B2/en active Active
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2020
- 2020-04-01 HR HRP20200537TT patent/HRP20200537T1/hr unknown
- 2020-04-06 CY CY20201100319T patent/CY1123042T1/el unknown
- 2020-08-07 US US16/987,695 patent/US10966991B2/en active Active
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2021
- 2021-02-24 US US17/184,181 patent/US11628175B2/en active Active
- 2021-09-07 CY CY20211100793T patent/CY1124475T1/el unknown
- 2021-09-09 CY CY20211100797T patent/CY1124490T1/el unknown
Also Published As
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