MD2353C2 - Preparat antibiotic, procedeu de obţinere şi utilizările acestuia - Google Patents
Preparat antibiotic, procedeu de obţinere şi utilizările acestuiaInfo
- Publication number
- MD2353C2 MD2353C2 MDA20020073A MD20020073A MD2353C2 MD 2353 C2 MD2353 C2 MD 2353C2 MD A20020073 A MDA20020073 A MD A20020073A MD 20020073 A MD20020073 A MD 20020073A MD 2353 C2 MD2353 C2 MD 2353C2
- Authority
- MD
- Moldova
- Prior art keywords
- obtaining
- antibiotic preparation
- component
- preparation
- medicine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Medicines Containing Plant Substances (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Invenţia se referă la un preparat antibiotic, la un procedeu de obţinere a lui, care poate fi utilizat în medicină şi medicina veterinară pentru tratamentul infecţiilor microbiene locale în ţesuturile tari şi în cele moi.Esenţa procedeului constă în aceea că se amestecă cu apă un component amfifilic dintre sulfaţi, sulfamaţi sau sulfonaţi, unul sau mai multe antibiotice din grupa aminoglicozidelor, lincosamidelor sau tetraciclinelor, un component auxiliar organic şi/sau anorganic şi, eventual, cel puţin un component biologic activ.Preparatul obţinut poate fi utilizat ca implant resorbabil sau neresorbabil.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10114245A DE10114245A1 (de) | 2001-03-22 | 2001-03-22 | Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung |
Publications (3)
Publication Number | Publication Date |
---|---|
MD20020073A MD20020073A (ro) | 2002-11-30 |
MD2353B2 MD2353B2 (ro) | 2004-01-31 |
MD2353C2 true MD2353C2 (ro) | 2004-08-31 |
Family
ID=7678692
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MDA20020073A MD2353C2 (ro) | 2001-03-22 | 2002-02-13 | Preparat antibiotic, procedeu de obţinere şi utilizările acestuia |
Country Status (32)
Country | Link |
---|---|
US (1) | US20020183265A1 (ro) |
EP (1) | EP1243258B1 (ro) |
JP (1) | JP2002275098A (ro) |
CN (1) | CN1286467C (ro) |
AT (1) | ATE259636T1 (ro) |
AU (1) | AU772160B2 (ro) |
BG (1) | BG65505B1 (ro) |
BR (1) | BR0201099A (ro) |
CA (1) | CA2378503C (ro) |
CZ (1) | CZ2002868A3 (ro) |
DE (2) | DE10114245A1 (ro) |
DK (1) | DK1243258T3 (ro) |
EE (1) | EE200200155A (ro) |
ES (1) | ES2213718T3 (ro) |
GE (1) | GEP20053450B (ro) |
HR (1) | HRP20020242B1 (ro) |
HU (1) | HUP0201043A2 (ro) |
IL (1) | IL148705A (ro) |
IS (1) | IS2499B (ro) |
MD (1) | MD2353C2 (ro) |
MX (1) | MXPA02003006A (ro) |
NO (1) | NO20021389L (ro) |
NZ (1) | NZ517920A (ro) |
PL (1) | PL204985B1 (ro) |
PT (1) | PT1243258E (ro) |
RU (1) | RU2212880C1 (ro) |
SA (1) | SA02230036B1 (ro) |
SK (1) | SK3952002A3 (ro) |
TR (1) | TR200400363T4 (ro) |
UA (1) | UA71993C2 (ro) |
YU (1) | YU11702A (ro) |
ZA (1) | ZA200202255B (ro) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IS6390A (is) | 2001-08-31 | 2003-03-03 | Heraeus Kulzer Gmbh & Co. Kg | Reynsla af sýklalyfjahúðun skrokka sem í eru örholrými, þannig húðuðum skrokkum og einnig af notkunþeirra |
IS6389A (is) | 2001-08-31 | 2003-03-03 | Heraeus Kulzer Gmbh & Co. Kg | Reynsla af sýklalyfjahúðun skrokka, sem í eru örholrými, og einnig af þannig húðuðum skrokkum og notkun þeirra |
DE10262176B4 (de) * | 2002-06-21 | 2007-10-04 | Heraeus Kulzer Gmbh | Verfahren zur Herstellung von antibiotisch beschichteten porösen Körpern sowie Verwendung |
DE10318991A1 (de) * | 2003-04-25 | 2004-11-18 | Heraeus Kulzer Gmbh & Co. Kg | Poröser Körper mit antibiotischer Beschichtung, Verfahren zur Herstellung sowie Verwendung |
ZA200604869B (en) | 2003-12-04 | 2007-11-28 | Univ Utah Res Found | Modified macromolecules and methods of making and using thereof |
DE102004060666B3 (de) | 2004-12-15 | 2006-03-30 | Heraeus Kulzer Gmbh | Antibiotikum/Antibiotika enthaltendes Knochenersatzmaterial mit retardierender Wirkstofffreisetzung |
DE102005002703C5 (de) | 2005-01-19 | 2013-07-04 | Heraeus Kulzer Gmbh | Antibiotische Beschichtung von Implantaten sowie Verfahren zur antibiotischen Beschichtung |
WO2008006083A2 (en) | 2006-07-07 | 2008-01-10 | Surmodics, Inc. | Beaded wound spacer device |
WO2008100262A1 (en) * | 2007-02-16 | 2008-08-21 | Alpharma, Inc. | Medicated feed premix comprising chlortetracycline hydrochloride |
DE102007063613B4 (de) * | 2007-04-24 | 2010-01-07 | Heraeus Kulzer Gmbh | Verwendung eines Spacer-Polymethylmethacrylat-Knochenzement |
DE102007039871A1 (de) | 2007-08-21 | 2009-02-26 | Friedrich-Baur-Gmbh | Weichgewebe-Implantat mit antibakterieller Wirkung |
CN101225125B (zh) * | 2008-01-18 | 2012-12-05 | 中国科学院烟台海岸带研究所 | 一种吸湿保湿剂及其制备方法 |
US8167836B2 (en) * | 2009-12-08 | 2012-05-01 | Taris Biomedical, Inc. | Tissue expander configured for drug delivery |
DE102010020940B4 (de) * | 2010-05-19 | 2014-09-25 | Heraeus Medical Gmbh | Antibiotische Beschichtung |
WO2013010045A1 (en) | 2011-07-12 | 2013-01-17 | Biotime Inc. | Novel methods and formulations for orthopedic cell therapy |
CN102391954B (zh) * | 2011-10-26 | 2014-12-10 | 厦门大学 | 球形棕囊藻培养液的除菌方法 |
CN102552885A (zh) * | 2011-12-16 | 2012-07-11 | 青岛海芬海洋生物科技有限公司 | 海洋生物痔疮及肛内上皮和直肠粘膜上皮细胞消炎修护液 |
CA2888241C (en) | 2012-10-16 | 2020-12-29 | Surmodics, Inc. | Wound packing device and methods |
RU2540468C2 (ru) * | 2012-11-06 | 2015-02-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Нижегородский государственный университет им. Н.И. Лобачевского"Российская Федерация | Способ получения композиционных рассасывающихся материалов на основе хитозана и полилактида |
MX2015012367A (es) | 2013-03-15 | 2016-05-31 | Taris Biomedical Llc | Dispositivos de suministro de farmacos con un componente permeable al farmaco y metodos. |
US10201457B2 (en) | 2014-08-01 | 2019-02-12 | Surmodics, Inc. | Wound packing device with nanotextured surface |
US10894150B2 (en) | 2015-04-23 | 2021-01-19 | Taris Biomedical Llc | Drug delivery devices with drug-permeable component and methods |
CN105999401B (zh) * | 2016-07-22 | 2019-03-08 | 武汉理工大学 | 一种基于羟基磷灰石的牙科抑菌修复材料及其制备方法 |
CN107459654B (zh) * | 2017-08-03 | 2020-05-26 | 天津大学 | 一种模拟抗菌肽共聚物及其制备方法 |
CN109674806B (zh) * | 2019-01-14 | 2021-10-26 | 福州奥尼多生物科技有限公司 | 春雷霉素在制备抗菌药物中的用途 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE821600A (fr) * | 1974-05-29 | 1975-02-17 | Nouveaux derives de la gentamicine | |
US4291013A (en) * | 1978-10-09 | 1981-09-22 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Medicinally useful, shaped mass of collagen resorbable in the body |
DE3248328A1 (de) * | 1982-12-28 | 1984-06-28 | Bayer Ag, 5090 Leverkusen | Schwerloesliche salze von aminoglykosiden sowie diese enthaltende formulierungen mit verzoegerter wirkstoff-freigabe |
US4617293A (en) * | 1981-05-13 | 1986-10-14 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Flavonoid phosphate salts of aminoglycoside antibiotics |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3091572A (en) * | 1962-07-16 | 1963-05-28 | Schering Corp | Gentamycin and method of production |
ES315101A1 (es) * | 1965-07-08 | 1966-01-01 | Folch Vazquez Conrado | Procedimiento de preparaciën de nuevos derivados de tetraciclina |
ES322771A1 (es) * | 1966-02-08 | 1966-11-16 | Folch Vazquez Conrado | Procedimiento para la preparaciën de laurilsulfato de tetraciclina |
FR6476M (ro) * | 1967-06-06 | 1968-11-18 | ||
DE2320373B2 (de) * | 1973-04-21 | 1978-04-06 | Merck Patent Gmbh, 6100 Darmstadt | Antibioticahaltiges Mittel und seine Verwendung als chirurgisches Kunststoffmaterial |
AR216922A1 (es) * | 1976-11-11 | 1980-02-15 | Merck Patent Gmbh | Procedimiento para la fabricacion de un medio quirurgico |
US5035891A (en) * | 1987-10-05 | 1991-07-30 | Syntex (U.S.A.) Inc. | Controlled release subcutaneous implant |
FR2668367B1 (fr) * | 1990-10-26 | 1994-05-13 | Centre Nal Recherc Scientifique | Medicament implantable a effet prolonge. |
US5709875A (en) * | 1990-10-26 | 1998-01-20 | Centre National De La Rechierche Scientifique (C.N.R.S) | Implantable biodegradable material and process for its production |
DE4404018A1 (de) * | 1994-02-09 | 1995-08-10 | Merck Patent Gmbh | Protrahiert freisetzende Darreichungsformen enthaltend Clindamycin-Palmitat |
WO1995027517A1 (fr) * | 1994-04-06 | 1995-10-19 | Lyzion Australia Pty. Ltd. | Preparation pharmaceutique pour application locale, et procede de fabrication |
US5614206A (en) * | 1995-03-07 | 1997-03-25 | Wright Medical Technology, Inc. | Controlled dissolution pellet containing calcium sulfate |
US5783217A (en) * | 1995-11-07 | 1998-07-21 | Etex Corporation | Low temperature calcium phosphate apatite and a method of its manufacture |
US5670142A (en) * | 1996-07-08 | 1997-09-23 | Donald Neudecker | Treatment for itch of chicken pox |
US5874418A (en) * | 1997-05-05 | 1999-02-23 | Cydex, Inc. | Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use |
US5980928A (en) * | 1997-07-29 | 1999-11-09 | Terry; Paul B. | Implant for preventing conjunctivitis in cattle |
US6428579B1 (en) * | 1998-07-01 | 2002-08-06 | Brown University Research Foundation | Implantable prosthetic devices coated with bioactive molecules |
DE10114364A1 (de) * | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Verfahren zur Herstellung von antibiotischen Kompositen |
DE10114244A1 (de) * | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Antibiotikum-/Antibiotika-Zubereitung mit retardierender Wirkstofffreisetzung |
-
2001
- 2001-03-22 DE DE10114245A patent/DE10114245A1/de not_active Ceased
-
2002
- 2002-02-13 MD MDA20020073A patent/MD2353C2/ro not_active IP Right Cessation
- 2002-02-15 IS IS6271A patent/IS2499B/is unknown
- 2002-02-19 GE GE4983A patent/GEP20053450B/en unknown
- 2002-02-20 YU YU11702A patent/YU11702A/sh unknown
- 2002-02-27 BG BG106456A patent/BG65505B1/bg unknown
- 2002-03-06 DE DE50200244T patent/DE50200244D1/de not_active Expired - Lifetime
- 2002-03-06 AT AT02005024T patent/ATE259636T1/de not_active IP Right Cessation
- 2002-03-06 ES ES02005024T patent/ES2213718T3/es not_active Expired - Lifetime
- 2002-03-06 TR TR2004/00363T patent/TR200400363T4/xx unknown
- 2002-03-06 PT PT02005024T patent/PT1243258E/pt unknown
- 2002-03-06 EP EP02005024A patent/EP1243258B1/de not_active Expired - Lifetime
- 2002-03-06 DK DK02005024T patent/DK1243258T3/da active
- 2002-03-08 CZ CZ2002868A patent/CZ2002868A3/cs unknown
- 2002-03-14 IL IL148705A patent/IL148705A/en not_active IP Right Cessation
- 2002-03-19 SK SK395-2002A patent/SK3952002A3/sk unknown
- 2002-03-19 US US10/101,254 patent/US20020183265A1/en not_active Abandoned
- 2002-03-19 JP JP2002076626A patent/JP2002275098A/ja active Pending
- 2002-03-20 ZA ZA200202255A patent/ZA200202255B/xx unknown
- 2002-03-20 MX MXPA02003006A patent/MXPA02003006A/es active IP Right Grant
- 2002-03-20 NO NO20021389A patent/NO20021389L/no not_active Application Discontinuation
- 2002-03-21 RU RU2002107210/14A patent/RU2212880C1/ru active
- 2002-03-21 HR HR20020242A patent/HRP20020242B1/xx not_active IP Right Cessation
- 2002-03-21 UA UA2002032264A patent/UA71993C2/uk unknown
- 2002-03-21 AU AU27562/02A patent/AU772160B2/en not_active Ceased
- 2002-03-21 PL PL352922A patent/PL204985B1/pl not_active IP Right Cessation
- 2002-03-21 NZ NZ517920A patent/NZ517920A/xx unknown
- 2002-03-21 HU HU0201043A patent/HUP0201043A2/hu unknown
- 2002-03-22 CN CNB021079757A patent/CN1286467C/zh not_active Expired - Fee Related
- 2002-03-22 EE EEP200200155A patent/EE200200155A/xx unknown
- 2002-03-22 BR BR0201099-2A patent/BR0201099A/pt not_active IP Right Cessation
- 2002-03-22 CA CA002378503A patent/CA2378503C/en not_active Expired - Fee Related
- 2002-04-02 SA SA02230036A patent/SA02230036B1/ar unknown
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE821600A (fr) * | 1974-05-29 | 1975-02-17 | Nouveaux derives de la gentamicine | |
US4291013A (en) * | 1978-10-09 | 1981-09-22 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Medicinally useful, shaped mass of collagen resorbable in the body |
US4617293A (en) * | 1981-05-13 | 1986-10-14 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Flavonoid phosphate salts of aminoglycoside antibiotics |
DE3248328A1 (de) * | 1982-12-28 | 1984-06-28 | Bayer Ag, 5090 Leverkusen | Schwerloesliche salze von aminoglykosiden sowie diese enthaltende formulierungen mit verzoegerter wirkstoff-freigabe |
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