HUP0201043A2 - Antibiotikum- és antibiotikus készítmény előállítása és alkalmazása - Google Patents

Antibiotikum- és antibiotikus készítmény előállítása és alkalmazása

Info

Publication number
HUP0201043A2
HUP0201043A2 HU0201043A HUP0201043A HUP0201043A2 HU P0201043 A2 HUP0201043 A2 HU P0201043A2 HU 0201043 A HU0201043 A HU 0201043A HU P0201043 A HUP0201043 A HU P0201043A HU P0201043 A2 HUP0201043 A2 HU P0201043A2
Authority
HU
Hungary
Prior art keywords
antibiotic
sulfates
antibiotics
appropriate
antibiotica
Prior art date
Application number
HU0201043A
Other languages
English (en)
Inventor
Klaus-Dieter Kühn
Matthias Schnabelrauch
Sebastian Vogt
Original Assignee
Heraeus Kulzer Gmbh & Co. Kg.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heraeus Kulzer Gmbh & Co. Kg. filed Critical Heraeus Kulzer Gmbh & Co. Kg.
Publication of HU0201043D0 publication Critical patent/HU0201043D0/hu
Publication of HUP0201043A2 publication Critical patent/HUP0201043A2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Neurosurgery (AREA)
  • Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány antibiotikumok és antibiotikus készítmények előállításávalés felhasználásával foglalkozik, melyek a humán- és állat-gyógyászatban a szilárd- és lágyszövetek helyi mikrobiálisfertőzéseinek kezelését biztosítják. A találmány szerint azantibiotikum-/antibiotikus készítményt a következőképpen állítják elő:vizet és a következő amfifil vegyületeket összekeverjük:alkilszulfátok, arilszulfátok, alkilarilszulfátok,cikloalkilszulfátok, alkilcikloalkilszulfátok, alkilszulfamátok,cikloalkilszulfamát, alkilcikloalkilszulfamátok, arilszulfamátok,alkilarilszulfamátok, alkilszulfonátok, zsírsav-2-szulfonátok,arilszulfonátok, alkilarilszulfonátok, cikloalkilszulfonátok,alkilcikloalkilszulfonátok, alkildiszulfátok, cikloalkildiszulfátok,alkildiszulfonátok, cikloalkildiszulfonátok, arildiszulfonátok,alkilarildiszulfonátok, ariltriszulfonátok és alkilariltriszulfonátok,valamint legalább egy antibiotikumot adnak hozzá, melyet a következőcsoportokból választanak ki: aminoglükozid antibiotikumok, lincosamidés tetraciklin antibiotikumok, mindezek egy szerves és/vagy szervetlensegédanyaggal és adott esetben legalább egy biológiailag aktívsegédanyaggal összekeverhetők, és adott esetben formatestté és/vagyszemcsévé és/vagy porrá és/vagy fóliává és vagy fonallá és/vagyszálakká alakíthatók. Ó
HU0201043A 2001-03-22 2002-03-21 Antibiotikum- és antibiotikus készítmény előállítása és alkalmazása HUP0201043A2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10114245A DE10114245A1 (de) 2001-03-22 2001-03-22 Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung

Publications (2)

Publication Number Publication Date
HU0201043D0 HU0201043D0 (hu) 2002-05-29
HUP0201043A2 true HUP0201043A2 (hu) 2003-02-28

Family

ID=7678692

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0201043A HUP0201043A2 (hu) 2001-03-22 2002-03-21 Antibiotikum- és antibiotikus készítmény előállítása és alkalmazása

Country Status (32)

Country Link
US (1) US20020183265A1 (hu)
EP (1) EP1243258B1 (hu)
JP (1) JP2002275098A (hu)
CN (1) CN1286467C (hu)
AT (1) ATE259636T1 (hu)
AU (1) AU772160B2 (hu)
BG (1) BG65505B1 (hu)
BR (1) BR0201099A (hu)
CA (1) CA2378503C (hu)
CZ (1) CZ2002868A3 (hu)
DE (2) DE10114245A1 (hu)
DK (1) DK1243258T3 (hu)
EE (1) EE200200155A (hu)
ES (1) ES2213718T3 (hu)
GE (1) GEP20053450B (hu)
HR (1) HRP20020242B1 (hu)
HU (1) HUP0201043A2 (hu)
IL (1) IL148705A (hu)
IS (1) IS2499B (hu)
MD (1) MD2353C2 (hu)
MX (1) MXPA02003006A (hu)
NO (1) NO20021389L (hu)
NZ (1) NZ517920A (hu)
PL (1) PL204985B1 (hu)
PT (1) PT1243258E (hu)
RU (1) RU2212880C1 (hu)
SA (1) SA02230036B1 (hu)
SK (1) SK3952002A3 (hu)
TR (1) TR200400363T4 (hu)
UA (1) UA71993C2 (hu)
YU (1) YU11702A (hu)
ZA (1) ZA200202255B (hu)

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IS6390A (is) 2001-08-31 2003-03-03 Heraeus Kulzer Gmbh & Co. Kg Reynsla af sýklalyfjahúðun skrokka sem í eru örholrými, þannig húðuðum skrokkum og einnig af notkunþeirra
DE10227935B4 (de) * 2002-06-21 2007-10-04 Heraeus Kulzer Gmbh Verfahren zur Herstellung einer antibiotische Beschichtung von porösen Körpern sowie Verwendung
DE10318991A1 (de) * 2003-04-25 2004-11-18 Heraeus Kulzer Gmbh & Co. Kg Poröser Körper mit antibiotischer Beschichtung, Verfahren zur Herstellung sowie Verwendung
ZA200604869B (en) 2003-12-04 2007-11-28 Univ Utah Res Found Modified macromolecules and methods of making and using thereof
DE102004060666B3 (de) 2004-12-15 2006-03-30 Heraeus Kulzer Gmbh Antibiotikum/Antibiotika enthaltendes Knochenersatzmaterial mit retardierender Wirkstofffreisetzung
DE102005002703C5 (de) 2005-01-19 2013-07-04 Heraeus Kulzer Gmbh Antibiotische Beschichtung von Implantaten sowie Verfahren zur antibiotischen Beschichtung
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CN101225125B (zh) * 2008-01-18 2012-12-05 中国科学院烟台海岸带研究所 一种吸湿保湿剂及其制备方法
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Also Published As

Publication number Publication date
EE200200155A (et) 2002-12-16
IL148705A (en) 2006-12-10
HRP20020242B1 (en) 2005-02-28
DE10114245A1 (de) 2002-10-02
JP2002275098A (ja) 2002-09-25
DK1243258T3 (da) 2004-06-21
UA71993C2 (en) 2005-01-17
ZA200202255B (en) 2002-10-10
GEP20053450B (en) 2005-02-25
EP1243258A1 (de) 2002-09-25
RU2212880C1 (ru) 2003-09-27
PL204985B1 (pl) 2010-02-26
SA02230036B1 (ar) 2007-02-27
IL148705A0 (en) 2002-09-12
EP1243258B1 (de) 2004-02-18
IS2499B (is) 2009-03-15
BR0201099A (pt) 2002-11-05
AU2756202A (en) 2002-09-26
NO20021389D0 (no) 2002-03-20
NZ517920A (en) 2003-02-28
HRP20020242A2 (en) 2002-12-31
SK3952002A3 (en) 2002-10-08
CA2378503C (en) 2008-09-16
CA2378503A1 (en) 2002-09-22
ES2213718T3 (es) 2004-09-01
PT1243258E (pt) 2004-07-30
ATE259636T1 (de) 2004-03-15
DE50200244D1 (de) 2004-03-25
PL352922A1 (en) 2002-09-23
BG106456A (en) 2002-10-31
US20020183265A1 (en) 2002-12-05
MD2353B2 (en) 2004-01-31
YU11702A (sh) 2004-12-31
AU772160B2 (en) 2004-04-08
TR200400363T4 (tr) 2004-03-22
MD20020073A (en) 2002-11-30
CZ2002868A3 (cs) 2002-11-13
MD2353C2 (ro) 2004-08-31
IS6271A (is) 2002-09-22
MXPA02003006A (es) 2003-08-20
NO20021389L (no) 2002-09-23
CN1286467C (zh) 2006-11-29
HU0201043D0 (hu) 2002-05-29
BG65505B1 (bg) 2008-10-31
CN1380064A (zh) 2002-11-20

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