MD20150089A2 - Formă preparativă farmaceutică conţinând fosfatidilcolină pentru tratarea colitei ulceroase - Google Patents
Formă preparativă farmaceutică conţinând fosfatidilcolină pentru tratarea colitei ulceroaseInfo
- Publication number
- MD20150089A2 MD20150089A2 MDA20150089A MD20150089A MD20150089A2 MD 20150089 A2 MD20150089 A2 MD 20150089A2 MD A20150089 A MDA20150089 A MD A20150089A MD 20150089 A MD20150089 A MD 20150089A MD 20150089 A2 MD20150089 A2 MD 20150089A2
- Authority
- MD
- Moldova
- Prior art keywords
- acid
- pharmaceutical formulation
- phosphatidylcholine
- ulcerative colitis
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Invenţia se referă la o formă preparativă farmaceutică care conţine un produs de fosfatidilcolină cu formula (I),unde R1 reprezintă radicalul unui acid gras saturat sau nesaturat cu 12...24 atomi de carbon, iar R2 reprezintă radicalul unui acid gras saturat sau nesaturat cu 12...24 atomi de carbon, şi unde produsul de fosfatidilcolină (FC) conţine următoarele cantităţi de acizi graşi (% mas. din cantitatea totală de acizi graşi din FC): 55…72 acid linoleic; 10…18 acid palmitic; 7…15 acid oleic; 2…8 acid linolenic; 2…8 acid stearic, şi cel puţin un excipient acceptabil farmaceutic pentru eliberarea întârziată; precum şi la un procedeu de preparare a formei preparative menţionate.Forma propusă poate fi utilizată pentru tratamentul îmbunătăţit sau prevenirea colitei ulceroase.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13161089 | 2013-03-26 | ||
| PCT/EP2014/055947 WO2014154683A1 (en) | 2013-03-26 | 2014-03-25 | Pharmaceutical formulation comprising phosphatidylcholine for the treatment of ulcerative colitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MD20150089A2 true MD20150089A2 (ro) | 2016-03-31 |
Family
ID=47913311
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDA20150089A MD20150089A2 (ro) | 2013-03-26 | 2014-03-25 | Formă preparativă farmaceutică conţinând fosfatidilcolină pentru tratarea colitei ulceroase |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US20160045523A1 (ro) |
| EP (1) | EP2978416B1 (ro) |
| JP (1) | JP6262843B2 (ro) |
| KR (1) | KR20150132841A (ro) |
| CN (1) | CN105377247B (ro) |
| AU (1) | AU2014243102B2 (ro) |
| BR (1) | BR112015023849A2 (ro) |
| CA (1) | CA2907401A1 (ro) |
| CL (1) | CL2015002832A1 (ro) |
| DK (1) | DK2978416T3 (ro) |
| EA (1) | EA029514B1 (ro) |
| ES (1) | ES2605650T3 (ro) |
| HK (1) | HK1217089A1 (ro) |
| HU (1) | HUE030707T2 (ro) |
| IL (1) | IL241019A0 (ro) |
| LT (1) | LT2978416T (ro) |
| MD (1) | MD20150089A2 (ro) |
| MX (1) | MX2015013511A (ro) |
| PE (1) | PE20160037A1 (ro) |
| PH (1) | PH12015502199A1 (ro) |
| PL (1) | PL2978416T3 (ro) |
| PT (1) | PT2978416T (ro) |
| SG (1) | SG11201507777TA (ro) |
| UA (1) | UA115585C2 (ro) |
| WO (1) | WO2014154683A1 (ro) |
| ZA (1) | ZA201507910B (ro) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ595080A (en) | 2009-02-16 | 2013-09-27 | Giuliani Int Ltd | Methods of treating hair related conditions |
| JP6301844B2 (ja) | 2012-02-09 | 2018-03-28 | ノグラ ファーマ リミテッド | 線維症の処置方法 |
| WO2017144725A1 (en) * | 2016-02-26 | 2017-08-31 | Nogra Pharma Limited | Methods of treating lactose intolerance |
| CA3128302A1 (en) | 2019-02-08 | 2020-08-13 | Nogra Pharma Limited | Process of making 3-(4'-aminophenyl)-2-methoxypropionic acid, and analogs and intermediates thereof |
| EP3936123A4 (en) * | 2019-03-05 | 2023-05-17 | Sichuan Gowell Pharmaceutical Co., Ltd. | FATTY ACID COMPOSITION AND USE THEREOF |
| CN113368118B (zh) * | 2021-07-21 | 2022-09-23 | 中国药科大学 | 磷脂酰胆碱在制备治疗溃疡性结肠炎的药物中的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3022136C2 (de) * | 1980-06-13 | 1986-07-17 | A. Nattermann & Cie GmbH, 5000 Köln | Verfahren zum Abfüllen von Phospholipide enthaltenden pharmazeutischen Massen in Hartkapseln |
| US4560655A (en) * | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
| IT1243981B (it) * | 1990-10-01 | 1994-06-28 | Fidia Spa | Composizioni per il trattamento della pelle contenenti derivati della b-fosfatidilcolina |
| US5453523A (en) * | 1993-06-16 | 1995-09-26 | Emulsion Technology, Inc. | Process for obtaining highly purified phosphatidylcholine |
| US5840332A (en) * | 1996-01-18 | 1998-11-24 | Perio Products Ltd. | Gastrointestinal drug delivery system |
| ES2211184T3 (es) * | 1998-08-06 | 2004-07-01 | Wolfgang Stremmel | Fosfatidilcolina como medicamento con efecto protector de mucosas. |
| ES2452351T3 (es) * | 2007-07-31 | 2014-04-01 | Pat Gmbh | Uso de fosfatidilcolina para el tratamiento de colitis ulcerosa dependiente de esteroides y refractaria a esteroides |
| CN102633832B (zh) * | 2011-02-09 | 2015-07-22 | 北京绿色金可生物技术股份有限公司 | 一种制备高纯度磷脂酰胆碱的方法 |
-
2014
- 2014-03-25 PT PT147138085T patent/PT2978416T/pt unknown
- 2014-03-25 PL PL14713808T patent/PL2978416T3/pl unknown
- 2014-03-25 CA CA2907401A patent/CA2907401A1/en not_active Abandoned
- 2014-03-25 JP JP2016504634A patent/JP6262843B2/ja not_active Expired - Fee Related
- 2014-03-25 EA EA201591510A patent/EA029514B1/ru not_active IP Right Cessation
- 2014-03-25 WO PCT/EP2014/055947 patent/WO2014154683A1/en active Application Filing
- 2014-03-25 PE PE2015002052A patent/PE20160037A1/es not_active Application Discontinuation
- 2014-03-25 HU HUE14713808A patent/HUE030707T2/en unknown
- 2014-03-25 KR KR1020157029385A patent/KR20150132841A/ko not_active Application Discontinuation
- 2014-03-25 ES ES14713808.5T patent/ES2605650T3/es active Active
- 2014-03-25 US US14/779,418 patent/US20160045523A1/en not_active Abandoned
- 2014-03-25 CN CN201480017688.2A patent/CN105377247B/zh not_active Expired - Fee Related
- 2014-03-25 LT LTEP14713808.5T patent/LT2978416T/lt unknown
- 2014-03-25 MX MX2015013511A patent/MX2015013511A/es unknown
- 2014-03-25 EP EP14713808.5A patent/EP2978416B1/en not_active Not-in-force
- 2014-03-25 BR BR112015023849A patent/BR112015023849A2/pt not_active Application Discontinuation
- 2014-03-25 DK DK14713808.5T patent/DK2978416T3/en active
- 2014-03-25 SG SG11201507777TA patent/SG11201507777TA/en unknown
- 2014-03-25 AU AU2014243102A patent/AU2014243102B2/en not_active Ceased
- 2014-03-25 UA UAA201509138A patent/UA115585C2/uk unknown
- 2014-03-25 MD MDA20150089A patent/MD20150089A2/ro not_active Application Discontinuation
-
2015
- 2015-09-01 IL IL241019A patent/IL241019A0/en unknown
- 2015-09-21 PH PH12015502199A patent/PH12015502199A1/en unknown
- 2015-09-22 CL CL2015002832A patent/CL2015002832A1/es unknown
- 2015-10-23 ZA ZA2015/07910A patent/ZA201507910B/en unknown
-
2016
- 2016-05-04 HK HK16105070.4A patent/HK1217089A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK2978416T3 (en) | 2016-12-19 |
| CN105377247A (zh) | 2016-03-02 |
| US20160045523A1 (en) | 2016-02-18 |
| PT2978416T (pt) | 2016-12-09 |
| EP2978416A1 (en) | 2016-02-03 |
| SG11201507777TA (en) | 2015-10-29 |
| JP2016516087A (ja) | 2016-06-02 |
| BR112015023849A2 (pt) | 2017-07-18 |
| KR20150132841A (ko) | 2015-11-26 |
| ES2605650T3 (es) | 2017-03-15 |
| UA115585C2 (uk) | 2017-11-27 |
| HUE030707T2 (en) | 2017-05-29 |
| CN105377247B (zh) | 2019-04-26 |
| IL241019A0 (en) | 2015-11-30 |
| ZA201507910B (en) | 2017-04-26 |
| HK1217089A1 (zh) | 2016-12-23 |
| AU2014243102A1 (en) | 2015-09-17 |
| AU2014243102B2 (en) | 2018-04-26 |
| MX2015013511A (es) | 2016-06-28 |
| JP6262843B2 (ja) | 2018-01-17 |
| EP2978416B1 (en) | 2016-10-26 |
| CL2015002832A1 (es) | 2016-03-11 |
| WO2014154683A1 (en) | 2014-10-02 |
| LT2978416T (lt) | 2016-12-12 |
| CA2907401A1 (en) | 2014-10-02 |
| PH12015502199A1 (en) | 2016-01-25 |
| PL2978416T3 (pl) | 2017-03-31 |
| EA201591510A1 (ru) | 2016-01-29 |
| EA029514B1 (ru) | 2018-04-30 |
| PE20160037A1 (es) | 2016-02-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA9A | Abandonment or withdrawal of application (patent for invention) |