MC1258A1 - Derives pyrrolidiniques - Google Patents

Derives pyrrolidiniques

Info

Publication number
MC1258A1
MC1258A1 MC791363A MC1363A MC1258A1 MC 1258 A1 MC1258 A1 MC 1258A1 MC 791363 A MC791363 A MC 791363A MC 1363 A MC1363 A MC 1363A MC 1258 A1 MC1258 A1 MC 1258A1
Authority
MC
Monaco
Prior art keywords
methoxybenzyl
pyrrolidinic
compounds
general formula
derivatives
Prior art date
Application number
MC791363A
Other languages
English (en)
French (fr)
Inventor
E Kyburz
W Aschwanden
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC1258A1 publication Critical patent/MC1258A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
MC791363A 1978-02-10 1979-02-08 Derives pyrrolidiniques MC1258A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH140478 1978-02-10

Publications (1)

Publication Number Publication Date
MC1258A1 true MC1258A1 (fr) 1980-01-14

Family

ID=4209637

Family Applications (1)

Application Number Title Priority Date Filing Date
MC791363A MC1258A1 (fr) 1978-02-10 1979-02-08 Derives pyrrolidiniques

Country Status (12)

Country Link
US (2) US4239770A (enExample)
EP (1) EP0003602B1 (enExample)
JP (1) JPS54117469A (enExample)
AU (1) AU525204B2 (enExample)
CA (1) CA1115212A (enExample)
DE (1) DE2967324D1 (enExample)
IE (1) IE48897B1 (enExample)
IL (1) IL56577A (enExample)
MC (1) MC1258A1 (enExample)
NZ (1) NZ189572A (enExample)
PH (1) PH14270A (enExample)
ZA (1) ZA79452B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1131959B (it) * 1979-08-09 1986-06-25 Hoffmann La Roche Derivati pirrolidinici
CH646149A5 (de) * 1981-02-05 1984-11-15 Hoffmann La Roche Pyrrolidin-derivat.
US4431662A (en) * 1981-03-06 1984-02-14 Hodgson Gordon L Jun 1-(1,3-Benzodioxol-5-yl)-2-pyrrolidinone and its medicinal use
EP0106988A1 (en) * 1982-09-02 1984-05-02 The Wellcome Foundation Limited Pharmacologically active lactam derivatives
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
DE3706399A1 (de) * 1987-02-27 1988-09-08 Boehringer Ingelheim Kg Mittel mit antidepressiver wirkung
IT1215587B (it) * 1987-06-26 1990-02-14 Roussel Maestretti Spa Derivati della 1-benzoil2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro impiego come sostanza medicinale.
IT1231921B (it) * 1989-06-12 1992-01-15 Sigma Tau Ind Farmaceuti 1-acil-2-pirrolidoni quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti
JP2803882B2 (ja) * 1990-02-20 1998-09-24 日清製粉株式会社 １―フエノキシカルボニル―２―ピロリジノン誘導体
IT1242043B (it) * 1990-12-21 1994-02-02 Sigma Tau Ind Farmaceuti Derivati della 1,2,3,4,-tetraidronaftilammina ad attivita' nootropica e composizioni farmaceutiche che li contengono.
US5780375A (en) * 1993-10-19 1998-07-14 E. I. Du Pont De Nemours And Company Thick film composition for modifying the electrical properties of a dielectric layer
EP3068782B1 (en) * 2013-11-13 2018-05-23 Vertex Pharmaceuticals Incorporated Methods of preparing inhibitors of influenza viruses replication

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2915430A (en) * 1958-09-30 1959-12-01 Gen Aniline & Film Corp Method of controlling nematodes with n-acylpyrrolidones
GB1039113A (en) 1964-08-06 1966-08-17 Ucb Sa New n-substituted lactams
ES425600A1 (es) * 1974-04-23 1977-01-16 Lafarquim Procedimiento de obtencion de un nuevo derivado de pirroli- dinona.
FR2294698A1 (fr) * 1974-12-18 1976-07-16 Synthelabo Nouveaux derives des methoxy-2 benzamides substitues, leurs sels, leur preparation et les medicaments qui en renferment
ES433723A1 (es) * 1975-01-10 1976-11-16 Lafarquim S A Lab Procedimiento de obtencion de un derivado de 2-pirrolidi- nona.
DE2616374A1 (de) * 1976-04-14 1977-10-27 Bayer Ag In 4-stellung amidoalkylierte phenole

Also Published As

Publication number Publication date
IL56577A (en) 1982-07-30
AU525204B2 (en) 1982-10-28
PH14270A (en) 1981-04-29
IL56577A0 (en) 1979-05-31
NZ189572A (en) 1985-01-31
JPS54117469A (en) 1979-09-12
IE790245L (en) 1979-08-10
US4349562A (en) 1982-09-14
CA1115212A (en) 1981-12-29
EP0003602B1 (de) 1984-12-12
DE2967324D1 (en) 1985-01-24
AU4388979A (en) 1979-08-16
EP0003602A1 (de) 1979-08-22
IE48897B1 (en) 1985-06-12
JPS6210206B2 (enExample) 1987-03-05
US4239770A (en) 1980-12-16
ZA79452B (en) 1980-02-27

Similar Documents

Publication Publication Date Title
EP0724452B1 (de) Pharmazeutische zusammensetzung mit cyclosporin a, einen vitamin e derivat und einen emulgator
MC1258A1 (fr) Derives pyrrolidiniques
MC1550A1 (fr) Forme de dosage orale
FR2513125A1 (fr) Medicament curatif du deficit immunitaire
FR2914188A1 (fr) Nouvelle composition a base d'oxime de cholest-4-en-3-one
BE895724A (fr) Nouvelle utilisation therapeutique de la dihydrocyclosporine d
DE3390114T1 (de) Verbesserte analgetische und antiinflammatorische, Ibuprofen enthaltende Zubereitungen und Verfahren zu ihrer Herstellung
AT400519B (de) Pharmazeutische zubereitungen mit einem gehalt an ace-inhibitor und dessen stabilisierung
BE1010483A5 (fr) Solution cutanee pour depot direct a usage anti-parasitaire chez les bovins et ovins.
EP0342139A2 (fr) Utilisation de l'Aspartate d'Arginine pour la fabrication d'un médicament pour traiter certains troubles de la mémoire
EP0108017B1 (fr) Association renfermant à titre de principes actifs, un analgésique central et la vitamine B12 ou un de ses analogues
DE4319438C1 (de) Arzneimittel auf der Grundlage von Ketoprofen zur Bekämpfung von Schmerzen und/oder Entzündungen und/oder Fieber an Menschen und Tieren
Jortner et al. Effects of prolonged tremor due to penitrem A in mice
CA1151067A (fr) COMPOSITIONS PHARMACEUTIQUES ANTIARYTHMIQUES A ACTION PROLONGEE DONT LE PRINCIPE ACTIF EST 1'.alpha.-/2-/BIS (1-METHYL ETHYL) AMINO (ETHYL) .alpha.-PHENYL 2-PYRIDINE ACETAMIDEOU L'UN DE SES SELS
WO1997000080A1 (de) Pharmazeutische zubereitung mit cyclosporin a
FR2467598A1 (fr) Composition dermatologique contenant un ou plusieurs triglycerides et son application au traitement de la peau vivante
EP0029790B1 (fr) Nouveau médicament à base d'aspirine et d'heptaminol
EP0287469B1 (fr) Assocation renfermant à titre de principes actifs, un analgésique central et la forskoline
EP1841459B1 (fr) Utilisation d'un derive de dihydroimidazopyrazine pour traiter ou prevenir la douleur
EP0766692B1 (fr) Derives de l'acide guanylique et applications comme medicaments
CH652924A5 (fr) Produits pharmaceutique ameliorant le metabolisme des lipides.
FR3051367A1 (fr) Composition pharmaceutique soulageant et prevenant les douleurs musculaires mimant les effets des peptides de venin de mamba noir (dendroaspis polylepsis)
CA1134272A (fr) Compose analgesique
FR2485372A1 (fr) Composition pharmaceutique pour le traitement des etats d'intoxication alcoolique aigue a base de 5-oxo-2-pyrrolidone carboxylate de pyridoxine et procede de preparation de ce dernier
FR2577422A1 (fr) Association renfermant a titre de principes actifs, un analgesique central et l'adenine ou l'adenosine ou l'un des analogues de l'adenosine

Legal Events

Date Code Title Description
NN Annulment
YP Annual fee paid