MA58885B1 - Formes cristallines d'un composé pharmaceutique - Google Patents

Formes cristallines d'un composé pharmaceutique

Info

Publication number
MA58885B1
MA58885B1 MA58885A MA58885A MA58885B1 MA 58885 B1 MA58885 B1 MA 58885B1 MA 58885 A MA58885 A MA 58885A MA 58885 A MA58885 A MA 58885A MA 58885 B1 MA58885 B1 MA 58885B1
Authority
MA
Morocco
Prior art keywords
compound
crystalline forms
pharmaceutical compound
relates
crystalline form
Prior art date
Application number
MA58885A
Other languages
English (en)
French (fr)
Inventor
Robert Hett
Fritz Blatter
Jennifer Robin
Kyle Landskroner
Original Assignee
Azafaros B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Azafaros B V filed Critical Azafaros B V
Publication of MA58885B1 publication Critical patent/MA58885B1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/46Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
MA58885A 2020-10-02 2021-10-01 Formes cristallines d'un composé pharmaceutique MA58885B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20199934.9A EP3978474A1 (en) 2020-10-02 2020-10-02 Crystalline forms of a pharmaceutical compound
PCT/EP2021/077100 WO2022069709A1 (en) 2020-10-02 2021-10-01 Crystalline forms of a pharmaceutical compound

Publications (1)

Publication Number Publication Date
MA58885B1 true MA58885B1 (fr) 2023-11-30

Family

ID=72744696

Family Applications (1)

Application Number Title Priority Date Filing Date
MA58885A MA58885B1 (fr) 2020-10-02 2021-10-01 Formes cristallines d'un composé pharmaceutique

Country Status (19)

Country Link
US (2) US12116344B2 (enExample)
EP (3) EP3978474A1 (enExample)
JP (2) JP2023524169A (enExample)
KR (2) KR102659466B1 (enExample)
CN (1) CN116390910A (enExample)
AU (2) AU2021353055B2 (enExample)
BR (2) BR112022018020B1 (enExample)
CA (1) CA3193939C (enExample)
CL (1) CL2023000943A1 (enExample)
DK (1) DK4114826T3 (enExample)
ES (1) ES2964105T3 (enExample)
FI (1) FI4114826T3 (enExample)
IL (2) IL301882B2 (enExample)
MA (1) MA58885B1 (enExample)
MX (1) MX2023003618A (enExample)
PE (1) PE20240138A1 (enExample)
TW (1) TW202229236A (enExample)
WO (1) WO2022069709A1 (enExample)
ZA (1) ZA202310184B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202337456A (zh) * 2022-01-10 2023-10-01 荷蘭商雅捷法羅斯公司 Gm2神經節苷脂症之治療
EP4209215A1 (en) * 2022-01-10 2023-07-12 Azafaros B.V. Treatment of gm2 gangliosidosis
WO2025162745A1 (en) 2024-02-01 2025-08-07 Azafaros B.V. Treatment of gm1 gangliosidosis
EP4595964A1 (en) 2024-02-01 2025-08-06 Azafaros B.V. Treatment of gm1 gangliosidosis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3122726B1 (en) 2014-03-27 2018-08-29 Academisch Medisch Centrum N-(5-((aryl or heteroaryl)methyloxy)pentyl)-substituted iminosugars as inhibitors of glucosylceramide synthase
JP2018527946A (ja) * 2015-06-24 2018-09-27 ウニフェルシタイト・ライデン グリコシル化代謝産物

Also Published As

Publication number Publication date
EP4295847A2 (en) 2023-12-27
US12116344B2 (en) 2024-10-15
JP2023524169A (ja) 2023-06-08
AU2021353055A1 (en) 2022-09-15
US20240287001A9 (en) 2024-08-29
ZA202310184B (en) 2024-01-31
MX2023003618A (es) 2023-07-14
IL301882B1 (en) 2024-12-01
JP2024054192A (ja) 2024-04-16
IL301882A (en) 2023-06-01
TW202229236A (zh) 2022-08-01
AU2021353055B2 (en) 2022-10-06
WO2022069709A1 (en) 2022-04-07
EP4114826A1 (en) 2023-01-11
CA3193939C (en) 2024-02-20
BR112022018020A2 (pt) 2023-04-18
FI4114826T3 (fi) 2023-11-21
KR20240056628A (ko) 2024-04-30
DK4114826T3 (da) 2023-11-13
EP3978474A1 (en) 2022-04-06
KR20230078798A (ko) 2023-06-02
US20250059137A1 (en) 2025-02-20
IL316634A (en) 2024-12-01
EP4114826B1 (en) 2023-08-23
IL301882B2 (en) 2025-04-01
PE20240138A1 (es) 2024-01-30
CN116390910A (zh) 2023-07-04
AU2022291486B2 (en) 2024-07-25
NZ798892A (en) 2023-09-29
AU2022291486A1 (en) 2023-02-02
US20230391724A1 (en) 2023-12-07
CA3193939A1 (en) 2022-04-07
BR122022018214A2 (pt) 2023-05-09
CL2023000943A1 (es) 2023-09-29
ES2964105T3 (es) 2024-04-04
KR102659466B1 (ko) 2024-04-19
BR112022018020B1 (pt) 2023-12-26
EP4295847A3 (en) 2024-02-28

Similar Documents

Publication Publication Date Title
MA58885B1 (fr) Formes cristallines d'un composé pharmaceutique
TN2009000059A1 (fr) Formes de dosage pharmaceutiques orales anti-manipulation contenant un analgesique opioide
MA49235A (fr) Modulateur de régulateur de conductance transmembranaire de fibrose kystique, compositions pharmaceutiques, procédés de traitement et procédé de fabrication du modulateur
Slotte et al. Gene expression of inflammation and bone healing in peri‐implant crevicular fluid after placement and loading of dental implants. A kinetic clinical pilot study using quantitative real‐time PCR
MA29378B1 (fr) Composition pharmaceutique comprenant une diphenyluree substituee par un omega-carboxyaryle pour le traitement du cancer
MA30723B1 (fr) Benzoxazoles et oxazolopyridines utiles en tant qu'inhibiteurs des janus kinases.
US20160287587A1 (en) Modification of amyloid-beta load in non-brain tissue
AR029437A1 (es) Tratamiento de la enfermedad neurodegenerativa
MA30073B1 (fr) Derives de piperidine 3,5-substitues en tant qu'inhibiteurs de renine
MA30335B1 (fr) Compositions antibiotiques a liberation modifiee et leur procede de production
BR0213138A (pt) Métodos de tratar ou prevenir mal de alzheimer e uma doença distinguida por depósito de beta-amilóide no cérebro, de tratar um paciente que tenha, ou de prevenir um paciente de contrair uma doença ou condição, de produzir um complexo de beta-secretase e de inibir a produção de placa beta-amilóide em um animal, composição e uso de um composto
DE112011105169T5 (de) Neue pharmazeutische Zusammensetzung mit geringen Nebenwirkungen enthaltend anti-Tuberkulose Arzneimittel
BR0210392A (pt) Composto, métodos de tratar um paciente que tenha ou de prevenir um paciente de contrair uma doença ou condição e de preparar um composto, e, uso de um composto
BRPI0409151A (pt) uso de derivados de 10-hidróxi-10,11-diidrocarbamazepina para o tratamento de transtornos afetivos
MA56330B1 (fr) Composition pharmaceutique comprenant un composé de tétrahydropyrazolopyrimidinone
MA31204B1 (fr) Sels d'addition acides, hydrates et polymorphes d'ethylamide d'acide 5-(2,4-dihydroxy-5-isopropyl-phenyl) -4-(4-morpholin-4-ylmethyl-phenyl)-isoxazole-3-carboxylique et preparations comprenant ces formes
KR20140090161A (ko) 트랜스타이레틴―관련 아밀로이드증에 대한 신규 치료법
CN1093401C (zh) 活性氧、自由基去除剂
MA29950B1 (fr) Nouveau derive de la pleuromutiline et son utilisation
BR0211030A (pt) Derivado de pirrolidina oxadiazole, uso de um derivado de pirrolidina oxadiazole, composição farmacêutica contendo pelo menos um derivado de pirrolidina oxadiazole, método para preparação de um composto de pirrolidina oxadiazole
MA24704A1 (fr) Formulations nouvelles de paroxetine et procede pour leur preparation
US10258623B2 (en) Compositions and methods for reduction of amyloid-beta load
EP0368994B1 (en) Benzothiazepines for the preparation of medicaments for the amelioration of epileptic seizures
Mori et al. Morphometric and microscopic evaluation of the effect of solution of acetazolamide as an intracanal therapeutic agent in late reimplanted rat teeth
MA27690A1 (fr) Composition pharmaceutique androgene et procede pour le traitement de la depression.