CL2023000943A1 - Formas cristalinas de un compuesto farmacéutico. - Google Patents

Formas cristalinas de un compuesto farmacéutico.

Info

Publication number
CL2023000943A1
CL2023000943A1 CL2023000943A CL2023000943A CL2023000943A1 CL 2023000943 A1 CL2023000943 A1 CL 2023000943A1 CL 2023000943 A CL2023000943 A CL 2023000943A CL 2023000943 A CL2023000943 A CL 2023000943A CL 2023000943 A1 CL2023000943 A1 CL 2023000943A1
Authority
CL
Chile
Prior art keywords
compound
crystalline form
crystalline forms
pharmaceutical compound
relates
Prior art date
Application number
CL2023000943A
Other languages
English (en)
Spanish (es)
Inventor
Robert Hett
Fritz Blatter
Jennifer Robin
Kyle Landskroner
Original Assignee
Azafaros B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Azafaros B V filed Critical Azafaros B V
Publication of CL2023000943A1 publication Critical patent/CL2023000943A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/46Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
CL2023000943A 2020-10-02 2023-03-30 Formas cristalinas de un compuesto farmacéutico. CL2023000943A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20199934.9A EP3978474A1 (en) 2020-10-02 2020-10-02 Crystalline forms of a pharmaceutical compound

Publications (1)

Publication Number Publication Date
CL2023000943A1 true CL2023000943A1 (es) 2023-09-29

Family

ID=72744696

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2023000943A CL2023000943A1 (es) 2020-10-02 2023-03-30 Formas cristalinas de un compuesto farmacéutico.

Country Status (19)

Country Link
US (2) US12116344B2 (enExample)
EP (3) EP3978474A1 (enExample)
JP (2) JP2023524169A (enExample)
KR (2) KR20240056628A (enExample)
CN (1) CN116390910A (enExample)
AU (2) AU2021353055B2 (enExample)
BR (2) BR122022018214A2 (enExample)
CA (1) CA3193939C (enExample)
CL (1) CL2023000943A1 (enExample)
DK (1) DK4114826T3 (enExample)
ES (1) ES2964105T3 (enExample)
FI (1) FI4114826T3 (enExample)
IL (2) IL301882B2 (enExample)
MA (1) MA58885B1 (enExample)
MX (1) MX2023003618A (enExample)
PE (1) PE20240138A1 (enExample)
TW (1) TW202229236A (enExample)
WO (1) WO2022069709A1 (enExample)
ZA (1) ZA202310184B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250120958A1 (en) * 2022-01-10 2025-04-17 Azafaros B.V. Treatment of GM2 Gangliosidosis
EP4209215A1 (en) * 2022-01-10 2023-07-12 Azafaros B.V. Treatment of gm2 gangliosidosis
WO2025162745A1 (en) 2024-02-01 2025-08-07 Azafaros B.V. Treatment of gm1 gangliosidosis
EP4595964A1 (en) 2024-02-01 2025-08-06 Azafaros B.V. Treatment of gm1 gangliosidosis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015147639A1 (en) 2014-03-27 2015-10-01 Academisch Medisch Centrum N-(5-((aryl or heteroaryl)methyloxy)pentyl)-substituted iminosugars as inhibitors of glucosylceramide synthase
EP3314009A2 (en) * 2015-06-24 2018-05-02 Universiteit Leiden Glycosylated metabolites

Also Published As

Publication number Publication date
US20240287001A9 (en) 2024-08-29
FI4114826T3 (fi) 2023-11-21
KR20230078798A (ko) 2023-06-02
MA58885B1 (fr) 2023-11-30
IL301882A (en) 2023-06-01
TW202229236A (zh) 2022-08-01
IL301882B1 (en) 2024-12-01
CA3193939C (en) 2024-02-20
PE20240138A1 (es) 2024-01-30
ES2964105T3 (es) 2024-04-04
KR20240056628A (ko) 2024-04-30
DK4114826T3 (da) 2023-11-13
EP3978474A1 (en) 2022-04-06
BR112022018020A2 (pt) 2023-04-18
AU2021353055B2 (en) 2022-10-06
CA3193939A1 (en) 2022-04-07
JP2023524169A (ja) 2023-06-08
IL301882B2 (en) 2025-04-01
WO2022069709A1 (en) 2022-04-07
MX2023003618A (es) 2023-07-14
AU2022291486B2 (en) 2024-07-25
US20230391724A1 (en) 2023-12-07
EP4114826A1 (en) 2023-01-11
KR102659466B1 (ko) 2024-04-19
IL316634A (en) 2024-12-01
ZA202310184B (en) 2024-01-31
BR112022018020B1 (pt) 2023-12-26
EP4114826B1 (en) 2023-08-23
EP4295847A2 (en) 2023-12-27
JP2024054192A (ja) 2024-04-16
CN116390910A (zh) 2023-07-04
EP4295847A3 (en) 2024-02-28
US20250059137A1 (en) 2025-02-20
BR122022018214A2 (pt) 2023-05-09
AU2022291486A1 (en) 2023-02-02
US12116344B2 (en) 2024-10-15
AU2021353055A1 (en) 2022-09-15
NZ798892A (en) 2023-09-29

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