MA58885B1 - Formes cristallines d'un composé pharmaceutique - Google Patents
Formes cristallines d'un composé pharmaceutiqueInfo
- Publication number
- MA58885B1 MA58885B1 MA58885A MA58885A MA58885B1 MA 58885 B1 MA58885 B1 MA 58885B1 MA 58885 A MA58885 A MA 58885A MA 58885 A MA58885 A MA 58885A MA 58885 B1 MA58885 B1 MA 58885B1
- Authority
- MA
- Morocco
- Prior art keywords
- compound
- crystalline forms
- pharmaceutical compound
- relates
- crystalline form
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 239000013078 crystal Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000002305 glucosylceramides Chemical class 0.000 abstract 1
- 150000002339 glycosphingolipids Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Abstract
La présente invention concerne une forme cristalline du composé (i) et un procédé de fabrication de la forme cristalline du composé (i). L'invention concerne également des compositions pharmaceutiques comprenant la forme cristalline du composé (i). En outre, l'invention concerne des procédés d'utilisation de cette forme cristalline du composé (i) en tant que médicament et dans le traitement d'une maladie impliquant des taux anormaux de glucosylcéramide et/ou des taux accrus de glycosphingolipides.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20199934.9A EP3978474A1 (fr) | 2020-10-02 | 2020-10-02 | Formes cristallines d'un composé pharmaceutique |
PCT/EP2021/077100 WO2022069709A1 (fr) | 2020-10-02 | 2021-10-01 | Formes cristallines d'un composé pharmaceutique |
Publications (1)
Publication Number | Publication Date |
---|---|
MA58885B1 true MA58885B1 (fr) | 2023-11-30 |
Family
ID=72744696
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA58885A MA58885B1 (fr) | 2020-10-02 | 2021-10-01 | Formes cristallines d'un composé pharmaceutique |
Country Status (19)
Country | Link |
---|---|
US (1) | US20240287001A9 (fr) |
EP (3) | EP3978474A1 (fr) |
JP (2) | JP2023524169A (fr) |
KR (2) | KR102659466B1 (fr) |
CN (1) | CN116390910A (fr) |
AU (2) | AU2021353055B2 (fr) |
BR (2) | BR122022018214A2 (fr) |
CA (1) | CA3193939C (fr) |
CL (1) | CL2023000943A1 (fr) |
DK (1) | DK4114826T3 (fr) |
ES (1) | ES2964105T3 (fr) |
FI (1) | FI4114826T3 (fr) |
IL (1) | IL301882A (fr) |
MA (1) | MA58885B1 (fr) |
MX (1) | MX2023003618A (fr) |
PE (1) | PE20240138A1 (fr) |
TW (1) | TW202229236A (fr) |
WO (1) | WO2022069709A1 (fr) |
ZA (1) | ZA202310184B (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP4209215A1 (fr) * | 2022-01-10 | 2023-07-12 | Azafaros B.V. | Traitement de gm2 gangliosidosis |
IL314212A (en) * | 2022-01-10 | 2024-09-01 | Azafaros B V | Treatment of GM2 gangliosidosis |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3122726B1 (fr) | 2014-03-27 | 2018-08-29 | Academisch Medisch Centrum | Iminosucres n-(5-((aryl ou hétéroaryl)méthyloxy)pentyl)-substitués comme inhibiteurs de glucosylcéramide synthase |
US20190195897A1 (en) | 2015-06-24 | 2019-06-27 | Universiteit Leiden | Glycosylated metabolites |
-
2020
- 2020-10-02 EP EP20199934.9A patent/EP3978474A1/fr not_active Withdrawn
-
2021
- 2021-10-01 JP JP2022577645A patent/JP2023524169A/ja active Pending
- 2021-10-01 WO PCT/EP2021/077100 patent/WO2022069709A1/fr active Application Filing
- 2021-10-01 MA MA58885A patent/MA58885B1/fr unknown
- 2021-10-01 BR BR122022018214-3A patent/BR122022018214A2/pt not_active Application Discontinuation
- 2021-10-01 IL IL301882A patent/IL301882A/en unknown
- 2021-10-01 TW TW110136766A patent/TW202229236A/zh unknown
- 2021-10-01 FI FIEP21798287.5T patent/FI4114826T3/fi active
- 2021-10-01 ES ES21798287T patent/ES2964105T3/es active Active
- 2021-10-01 EP EP23191550.5A patent/EP4295847A3/fr active Pending
- 2021-10-01 US US18/029,842 patent/US20240287001A9/en active Pending
- 2021-10-01 MX MX2023003618A patent/MX2023003618A/es unknown
- 2021-10-01 CN CN202180067242.0A patent/CN116390910A/zh active Pending
- 2021-10-01 AU AU2021353055A patent/AU2021353055B2/en active Active
- 2021-10-01 PE PE2023001212A patent/PE20240138A1/es unknown
- 2021-10-01 CA CA3193939A patent/CA3193939C/fr active Active
- 2021-10-01 EP EP21798287.5A patent/EP4114826B1/fr active Active
- 2021-10-01 KR KR1020237014953A patent/KR102659466B1/ko active IP Right Grant
- 2021-10-01 DK DK21798287.5T patent/DK4114826T3/da active
- 2021-10-01 KR KR1020247012671A patent/KR20240056628A/ko active Application Filing
- 2021-10-01 BR BR112022018020-9A patent/BR112022018020B1/pt active IP Right Grant
-
2022
- 2022-12-20 AU AU2022291486A patent/AU2022291486B2/en active Active
-
2023
- 2023-03-30 CL CL2023000943A patent/CL2023000943A1/es unknown
- 2023-10-30 ZA ZA2023/10184A patent/ZA202310184B/en unknown
-
2024
- 2024-02-02 JP JP2024015037A patent/JP2024054192A/ja active Pending
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