MA54643A - Multimères multivalents tronqués - Google Patents
Multimères multivalents tronquésInfo
- Publication number
- MA54643A MA54643A MA054643A MA54643A MA54643A MA 54643 A MA54643 A MA 54643A MA 054643 A MA054643 A MA 054643A MA 54643 A MA54643 A MA 54643A MA 54643 A MA54643 A MA 54643A
- Authority
- MA
- Morocco
- Prior art keywords
- multimers
- multivalent
- truncated
- truncated multimers
- multivalent truncated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/35—Valency
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/53—Hinge
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/54—F(ab')2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/66—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a swap of domains, e.g. CH3-CH2, VH-CL or VL-CH1
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862786806P | 2018-12-31 | 2018-12-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA54643A true MA54643A (fr) | 2021-11-10 |
Family
ID=69159894
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA054643A MA54643A (fr) | 2018-12-31 | 2019-12-30 | Multimères multivalents tronqués |
Country Status (11)
Country | Link |
---|---|
US (1) | US20220380440A1 (fr) |
EP (1) | EP3906256A1 (fr) |
JP (1) | JP7440516B2 (fr) |
KR (1) | KR20210111767A (fr) |
CN (2) | CN113439089A (fr) |
CA (1) | CA3124688A1 (fr) |
EA (1) | EA202191242A1 (fr) |
IL (1) | IL283701A (fr) |
MA (1) | MA54643A (fr) |
SG (1) | SG11202105926QA (fr) |
WO (1) | WO2020141974A1 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2024027120A1 (fr) * | 2022-08-05 | 2024-02-08 | Shanghai Kaijin Biotechnology , Ltd | Complexes polypeptidiques multi-spécifiques |
WO2024149381A1 (fr) * | 2023-01-13 | 2024-07-18 | Shanghai Kaijin Biotechnology, Ltd | Complexes polypeptidiques multi-spécifiques |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL132560A0 (en) * | 1997-05-02 | 2001-03-19 | Genentech Inc | A method for making multispecific antibodies having heteromultimeric and common components |
US6165476A (en) * | 1997-07-10 | 2000-12-26 | Beth Israel Deaconess Medical Center | Fusion proteins with an immunoglobulin hinge region linker |
EP1272647B1 (fr) * | 2000-04-11 | 2014-11-12 | Genentech, Inc. | Anticorps multivalents et leurs utilisations |
CA2965865C (fr) | 2002-07-18 | 2021-10-19 | Merus N.V. | Production par recombinaison de melanges d'anticorps |
AU2004260884B2 (en) * | 2003-07-22 | 2009-11-19 | Crucell Holland B.V. | Binding molecules against SARS-coronavirus and uses thereof |
WO2005063819A2 (fr) | 2003-12-23 | 2005-07-14 | Crucell Holland B.V. | Molecule de liaison humaine contre cd1a |
GB0614780D0 (en) * | 2006-07-25 | 2006-09-06 | Ucb Sa | Biological products |
ES2906344T3 (es) | 2008-06-27 | 2022-04-18 | Merus Nv | Animal murino transgénico productor de anticuerpos |
US20120195900A1 (en) * | 2010-12-22 | 2012-08-02 | Abbott Laboratories | Tri-variable domain binding proteins and uses thereof |
KR101886983B1 (ko) * | 2011-08-23 | 2018-08-08 | 로슈 글리카트 아게 | 2 개의 fab 단편을 포함하는 fc-부재 항체 및 이용 방법 |
JP2014533249A (ja) | 2011-11-07 | 2014-12-11 | メディミューン,エルエルシー | 多重特異性を持つ多価結合タンパク質およびその使用 |
AU2013249985B2 (en) | 2012-04-20 | 2017-11-23 | Merus N.V. | Methods and means for the production of Ig-like molecules |
ES2692951T3 (es) | 2012-09-27 | 2018-12-05 | Merus N.V. | Anticuerpos IgG biespecíficos como acopladores de células T |
KR20240042540A (ko) | 2014-02-28 | 2024-04-02 | 메뤼스 엔.페. | ErbB-2와 ErbB-3에 결합하는 항체 |
JP6771385B2 (ja) | 2014-02-28 | 2020-10-21 | メルス ナムローゼ フェンノートシャップ | 二重特異性抗体および医薬組成物 |
WO2016105450A2 (fr) * | 2014-12-22 | 2016-06-30 | Xencor, Inc. | Anticorps trispécifiques |
SI3365373T1 (sl) | 2015-10-23 | 2021-08-31 | Merus N.V. | Vezne molekule, ki zaviranjo rast raka |
CN105368904A (zh) * | 2015-11-30 | 2016-03-02 | 苏州康聚生物科技有限公司 | 一种免疫球蛋白g片段的制备方法及应用 |
WO2018045110A1 (fr) * | 2016-08-30 | 2018-03-08 | Xencor, Inc. | Anticorps immunomodulateurs bispécifiques qui se lient à des récepteurs de costimulation et de points de contrôle |
EP3675892A4 (fr) * | 2017-07-03 | 2021-10-06 | Torque Therapeutics, Inc. | Molécules de fusion immunostimulatrices et leurs utilisations |
AR115320A1 (es) | 2018-03-30 | 2020-12-23 | Merus Nv | Anticuerpo multivalente |
CN117157323A (zh) * | 2021-03-31 | 2023-12-01 | 美勒斯公司 | 新型多特异性抗体 |
-
2019
- 2019-12-30 CN CN201980086682.3A patent/CN113439089A/zh active Pending
- 2019-12-30 SG SG11202105926QA patent/SG11202105926QA/en unknown
- 2019-12-30 CN CN202111503436.9A patent/CN114249818A/zh active Pending
- 2019-12-30 EP EP19835854.1A patent/EP3906256A1/fr active Pending
- 2019-12-30 MA MA054643A patent/MA54643A/fr unknown
- 2019-12-30 EA EA202191242A patent/EA202191242A1/ru unknown
- 2019-12-30 CA CA3124688A patent/CA3124688A1/fr active Pending
- 2019-12-30 KR KR1020217020714A patent/KR20210111767A/ko unknown
- 2019-12-30 US US17/417,288 patent/US20220380440A1/en active Pending
- 2019-12-30 JP JP2021532958A patent/JP7440516B2/ja active Active
- 2019-12-30 WO PCT/NL2019/050880 patent/WO2020141974A1/fr unknown
-
2021
- 2021-06-03 IL IL283701A patent/IL283701A/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN113439089A (zh) | 2021-09-24 |
JP2022519338A (ja) | 2022-03-23 |
EP3906256A1 (fr) | 2021-11-10 |
CN114249818A (zh) | 2022-03-29 |
US20220380440A1 (en) | 2022-12-01 |
CA3124688A1 (fr) | 2020-07-09 |
SG11202105926QA (en) | 2021-07-29 |
KR20210111767A (ko) | 2021-09-13 |
TW202039577A (zh) | 2020-11-01 |
IL283701A (en) | 2021-07-29 |
JP7440516B2 (ja) | 2024-02-28 |
WO2020141974A1 (fr) | 2020-07-09 |
EA202191242A1 (ru) | 2021-11-25 |
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