SG11202105926QA - Truncated multivalent multimers - Google Patents
Truncated multivalent multimersInfo
- Publication number
- SG11202105926QA SG11202105926QA SG11202105926QA SG11202105926QA SG11202105926QA SG 11202105926Q A SG11202105926Q A SG 11202105926QA SG 11202105926Q A SG11202105926Q A SG 11202105926QA SG 11202105926Q A SG11202105926Q A SG 11202105926QA SG 11202105926Q A SG11202105926Q A SG 11202105926QA
- Authority
- SG
- Singapore
- Prior art keywords
- truncated
- multivalent multimers
- multimers
- multivalent
- truncated multivalent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/35—Valency
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/53—Hinge
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/54—F(ab')2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/66—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a swap of domains, e.g. CH3-CH2, VH-CL or VL-CH1
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862786806P | 2018-12-31 | 2018-12-31 | |
| PCT/NL2019/050880 WO2020141974A1 (en) | 2018-12-31 | 2019-12-30 | Truncated multivalent multimers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202105926QA true SG11202105926QA (en) | 2021-07-29 |
Family
ID=69159894
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202105926QA SG11202105926QA (en) | 2018-12-31 | 2019-12-30 | Truncated multivalent multimers |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220380440A1 (en) |
| EP (1) | EP3906256A1 (en) |
| JP (1) | JP7440516B2 (en) |
| KR (1) | KR20210111767A (en) |
| CN (2) | CN113439089A (en) |
| CA (1) | CA3124688A1 (en) |
| EA (1) | EA202191242A1 (en) |
| IL (1) | IL283701A (en) |
| MA (1) | MA54643A (en) |
| SG (1) | SG11202105926QA (en) |
| WO (1) | WO2020141974A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024027120A1 (en) * | 2022-08-05 | 2024-02-08 | Shanghai Kaijin Biotechnology , Ltd | Multi-specific polypeptide complexes |
| WO2024149381A1 (en) * | 2023-01-13 | 2024-07-18 | Shanghai Kaijin Biotechnology, Ltd | Multi-specific polypeptide complexes |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL132560A0 (en) * | 1997-05-02 | 2001-03-19 | Genentech Inc | A method for making multispecific antibodies having heteromultimeric and common components |
| US6165476A (en) * | 1997-07-10 | 2000-12-26 | Beth Israel Deaconess Medical Center | Fusion proteins with an immunoglobulin hinge region linker |
| EP1272647B1 (en) * | 2000-04-11 | 2014-11-12 | Genentech, Inc. | Multivalent antibodies and uses therefor |
| CA2965865C (en) | 2002-07-18 | 2021-10-19 | Merus N.V. | Recombinant production of mixtures of antibodies |
| AU2004260884B2 (en) * | 2003-07-22 | 2009-11-19 | Crucell Holland B.V. | Binding molecules against SARS-coronavirus and uses thereof |
| WO2005063819A2 (en) | 2003-12-23 | 2005-07-14 | Crucell Holland B.V. | Human binding molecule against cd1a |
| GB0614780D0 (en) * | 2006-07-25 | 2006-09-06 | Ucb Sa | Biological products |
| ES2906344T3 (en) | 2008-06-27 | 2022-04-18 | Merus Nv | Antibody-producing transgenic murine animal |
| US20120195900A1 (en) * | 2010-12-22 | 2012-08-02 | Abbott Laboratories | Tri-variable domain binding proteins and uses thereof |
| KR101886983B1 (en) * | 2011-08-23 | 2018-08-08 | 로슈 글리카트 아게 | Fc-free antibodies comprising two fab fragments and methods of use |
| JP2014533249A (en) | 2011-11-07 | 2014-12-11 | メディミューン，エルエルシー | Multispecific binding proteins with multispecificity and uses thereof |
| AU2013249985B2 (en) | 2012-04-20 | 2017-11-23 | Merus N.V. | Methods and means for the production of Ig-like molecules |
| ES2692951T3 (en) | 2012-09-27 | 2018-12-05 | Merus N.V. | Bispecific IgG antibodies as T cell couplers |
| KR20240042540A (en) | 2014-02-28 | 2024-04-02 | 메뤼스 엔.페. | Antibody that binds erbb-2 and erbb-3 |
| JP6771385B2 (en) | 2014-02-28 | 2020-10-21 | メルス ナムローゼ フェンノートシャップ | Bispecific antibody and pharmaceutical composition |
| WO2016105450A2 (en) * | 2014-12-22 | 2016-06-30 | Xencor, Inc. | Trispecific antibodies |
| SI3365373T1 (en) | 2015-10-23 | 2021-08-31 | Merus N.V. | Binding molecules that inhibit cancer growth |
| CN105368904A (en) * | 2015-11-30 | 2016-03-02 | 苏州康聚生物科技有限公司 | Preparation method and application of immunoglobulin G fragment |
| WO2018045110A1 (en) * | 2016-08-30 | 2018-03-08 | Xencor, Inc. | Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors |
| EP3675892A4 (en) * | 2017-07-03 | 2021-10-06 | Torque Therapeutics, Inc. | Immunostimulatory fusion molecules and uses thereof |
| AR115320A1 (en) | 2018-03-30 | 2020-12-23 | Merus Nv | MULTIVALENT ANTIBODY |
| CN117157323A (en) * | 2021-03-31 | 2023-12-01 | 美勒斯公司 | Novel multispecific antibodies |
-
2019
- 2019-12-30 CN CN201980086682.3A patent/CN113439089A/en active Pending
- 2019-12-30 SG SG11202105926QA patent/SG11202105926QA/en unknown
- 2019-12-30 CN CN202111503436.9A patent/CN114249818A/en active Pending
- 2019-12-30 EP EP19835854.1A patent/EP3906256A1/en active Pending
- 2019-12-30 MA MA054643A patent/MA54643A/en unknown
- 2019-12-30 EA EA202191242A patent/EA202191242A1/en unknown
- 2019-12-30 CA CA3124688A patent/CA3124688A1/en active Pending
- 2019-12-30 KR KR1020217020714A patent/KR20210111767A/en unknown
- 2019-12-30 US US17/417,288 patent/US20220380440A1/en active Pending
- 2019-12-30 JP JP2021532958A patent/JP7440516B2/en active Active
- 2019-12-30 WO PCT/NL2019/050880 patent/WO2020141974A1/en unknown
-
2021
- 2021-06-03 IL IL283701A patent/IL283701A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN113439089A (en) | 2021-09-24 |
| JP2022519338A (en) | 2022-03-23 |
| EP3906256A1 (en) | 2021-11-10 |
| CN114249818A (en) | 2022-03-29 |
| US20220380440A1 (en) | 2022-12-01 |
| CA3124688A1 (en) | 2020-07-09 |
| MA54643A (en) | 2021-11-10 |
| KR20210111767A (en) | 2021-09-13 |
| TW202039577A (en) | 2020-11-01 |
| IL283701A (en) | 2021-07-29 |
| JP7440516B2 (en) | 2024-02-28 |
| WO2020141974A1 (en) | 2020-07-09 |
| EA202191242A1 (en) | 2021-11-25 |
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