MA54296A - Procédés de traitement du métabolisme lipidique dérégulé - Google Patents
Procédés de traitement du métabolisme lipidique déréguléInfo
- Publication number
- MA54296A MA54296A MA054296A MA54296A MA54296A MA 54296 A MA54296 A MA 54296A MA 054296 A MA054296 A MA 054296A MA 54296 A MA54296 A MA 54296A MA 54296 A MA54296 A MA 54296A
- Authority
- MA
- Morocco
- Prior art keywords
- treating
- methods
- lipid metabolism
- disregulated
- disregulated lipid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862771456P | 2018-11-26 | 2018-11-26 | |
| US201962817955P | 2019-03-13 | 2019-03-13 | |
| US201962890506P | 2019-08-22 | 2019-08-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA54296A true MA54296A (fr) | 2021-10-06 |
Family
ID=68988303
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA054296A MA54296A (fr) | 2018-11-26 | 2019-11-26 | Procédés de traitement du métabolisme lipidique dérégulé |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230132366A9 (https=) |
| EP (1) | EP3887401A2 (https=) |
| JP (1) | JP7607559B2 (https=) |
| CN (1) | CN113302206A (https=) |
| CA (1) | CA3120970A1 (https=) |
| MA (1) | MA54296A (https=) |
| WO (1) | WO2020112889A2 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112019016989A2 (pt) | 2017-02-17 | 2020-05-26 | Denali Therapeutics Inc. | Polipeptídeos de ligação ao receptor de transferrina manipulados |
| JOP20190248A1 (ar) | 2017-04-21 | 2019-10-20 | Amgen Inc | بروتينات ربط مولد ضد trem2 واستخداماته |
| AU2018308088B2 (en) | 2017-07-25 | 2025-05-29 | Truebinding, Inc. | Treating cancer by blocking the interaction of TIM-3 and its ligand |
| WO2020117715A1 (en) | 2018-12-03 | 2020-06-11 | Board Of Regents, The University Of Texas System | Oligo-benzamide analogs and their use in cancer treatment |
| AU2020214796A1 (en) | 2019-01-30 | 2021-07-29 | Truebinding, Inc. | Anti-Gal3 antibodies and uses thereof |
| PH12021552002A1 (en) | 2019-02-20 | 2022-09-19 | Denali Therapeutics Inc | Anti-trem2 antibodies and methods of use thereof |
| PE20221465A1 (es) | 2020-01-13 | 2022-09-21 | Denali Therapeutics Inc | Anticuerpos anti-trem2 y metodos para utilizarlos |
| TWI890727B (zh) | 2020-01-13 | 2025-07-21 | 美商戴納立製藥公司 | 抗trem2 抗體及其使用方法 |
| WO2021242776A2 (en) | 2020-05-26 | 2021-12-02 | Truebinding, Inc. | Methods of treating inflammatory diseases by blocking galectin-3 |
| AU2021289144A1 (en) * | 2020-06-11 | 2022-12-15 | King's College London | TREM2 chimeric receptor |
| MX2023001546A (es) * | 2020-08-05 | 2023-05-03 | Vigil Neuroscience Inc | Tratamiento de enfermedades relacionadas con la disfunción del receptor del factor 1 estimulante de colonias con agonistas trem2. |
| CN115015412B (zh) * | 2022-05-26 | 2024-07-05 | 江苏独步生物科技有限公司 | 一种与中枢神经损伤修复相关的分子靶标及其应用 |
| US20250101101A1 (en) | 2023-09-01 | 2025-03-27 | iTeos Belgium SA | Anti-trem2 antibodies and methods of use |
| WO2025064933A1 (en) * | 2023-09-22 | 2025-03-27 | The Trustees Of Columbia University In The City Of New York | Restoring tim4 in liver macrophages to treat non-alcoholic steatohepatitis (nash) |
| CN117771226B (zh) * | 2023-12-28 | 2024-08-20 | 山东博森医学工程技术有限公司 | 一种加快骨关节炎损伤修复的促进剂 |
| WO2025194147A1 (en) * | 2024-03-15 | 2025-09-18 | The Children's Medical Center Corporation | Therapeutic modulation of trem2 and uses thereof in retinal degeneration |
| CN118983095A (zh) * | 2024-08-01 | 2024-11-19 | 中国人民解放军总医院第五医学中心 | 脂质在hiv感染者抗逆转录病毒治疗后免疫重建结果预测中的应用 |
Family Cites Families (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR14523E (fr) | 1911-02-06 | 1911-12-30 | Daniel German Caswell | Perfectionnements dans les vélocipèdes |
| US4326055A (en) | 1977-12-22 | 1982-04-20 | Hoffmann-La Roche Inc. | Stilbene derivatives |
| DE3202100A1 (de) | 1982-01-23 | 1983-08-04 | Basf Ag, 6700 Ludwigshafen | Substituierte benzoesaeure-4-hydroxyanilide, ihre herstellung und diese enthaltende pharmazeutische zubereitungen |
| US4559157A (en) | 1983-04-21 | 1985-12-17 | Creative Products Resource Associates, Ltd. | Cosmetic applicator useful for skin moisturizing |
| LU84979A1 (fr) | 1983-08-30 | 1985-04-24 | Oreal | Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux |
| US4820508A (en) | 1987-06-23 | 1989-04-11 | Neutrogena Corporation | Skin protective composition |
| US4992478A (en) | 1988-04-04 | 1991-02-12 | Warner-Lambert Company | Antiinflammatory skin moisturizing composition and method of preparing same |
| US4938949A (en) | 1988-09-12 | 1990-07-03 | University Of New York | Treatment of damaged bone marrow and dosage units therefor |
| DE69224660C5 (de) | 1991-12-18 | 2010-06-02 | The Salk Institute For Biological Studies, La Jolla | Mitteln zur modulierung von verfahren durch retinoid rezeptoren und dafür nützliche verbindungen |
| DE10199033I2 (de) | 1992-04-22 | 2003-01-09 | Ligand Parmaceuticals Inc | Retinoid-x Rezeptor selektive Verbindungen |
| US5780676A (en) | 1992-04-22 | 1998-07-14 | Ligand Pharmaceuticals Incorporated | Compounds having selective activity for Retinoid X Receptors, and means for modulation of processes mediated by Retinoid X Receptors |
| US5466861A (en) | 1992-11-25 | 1995-11-14 | Sri International | Bridged bicyclic aromatic compounds and their use in modulating gene expression of retinoid receptors |
| JPH08511027A (ja) | 1993-01-11 | 1996-11-19 | リガンド・ファーマシューティカルズ・インコーポレーテッド | レチノイドxレセプターに対して選択的な活性を有する化合物、およびレチノイドxレセプターによって媒体されたプロセスの調節手段 |
| ATE187434T1 (de) | 1993-01-11 | 1999-12-15 | Ligand Pharm Inc | Selektivitaet fuer retinoid x rezeptoren enthaltende verbindungen |
| US5399586A (en) | 1993-03-11 | 1995-03-21 | Allergan, Inc. | Treatment of mammals afflicted with tumors with compounds having RXR retinoid receptor agonist activity |
| EP0694078A4 (en) | 1993-04-07 | 1997-06-25 | Ligand Pharm Inc | SORTING PROCESS RELATING TO RECEPTOR AGONISTS |
| ES2133798T3 (es) | 1994-08-10 | 1999-09-16 | Hoffmann La Roche | Ligandos del receptor x del acido retinoico. |
| CA2208981C (en) | 1994-12-30 | 2008-08-26 | Ligand Pharmaceuticals Incorporated | Novel trienoic retinoid compounds and methods |
| US5721103A (en) | 1994-12-30 | 1998-02-24 | Ligand Pharmaceuticals Incorporated | Trienoic retinoid compounds and methods |
| JPH09330101A (ja) | 1996-06-13 | 1997-12-22 | Kokusai Chodendo Sangyo Gijutsu Kenkyu Center | 制御装置及び方法 |
| IT1286031B1 (it) | 1996-10-24 | 1998-07-07 | Enichem Spa | Procedimento per la produzione di polimeri vinilaromatici ad elevato grado di sindiotassia |
| US6969711B2 (en) | 1997-05-26 | 2005-11-29 | Kowa Company, Ltd. | Cyclic diamine compounds and medicine containing the same |
| US6316503B1 (en) | 1999-03-15 | 2001-11-13 | Tularik Inc. | LXR modulators |
| WO2001041704A2 (en) | 1999-12-13 | 2001-06-14 | Merck & Co., Inc. | Method for the prevention and/or treatment of atherosclerosis |
| US20030086923A1 (en) | 1999-12-13 | 2003-05-08 | Sparrow Carl P. | Method for the prevention and/or treatment of atherosclerosis |
| US7482366B2 (en) | 2001-12-21 | 2009-01-27 | X-Ceptor Therapeutics, Inc. | Modulators of LXR |
| WO2003059884A1 (en) | 2001-12-21 | 2003-07-24 | X-Ceptor Therapeutics, Inc. | Modulators of lxr |
| US6828446B2 (en) | 2001-12-21 | 2004-12-07 | Pharmacia Corporation | Aromatic thioether liver X-receptor modulators |
| AU2003217276A1 (en) | 2002-02-28 | 2003-09-16 | Eli Lilly And Company | Method of treating atherosclerosis and hypercholesterolemia |
| MXPA04011691A (es) | 2002-05-24 | 2005-09-12 | Pharmacia Corp | Moduladores del receptor x anilino hepaticos. |
| MXPA04011690A (es) | 2002-05-24 | 2005-03-31 | Pharmacia Corp | Moduladores de receptor x de higado de sulfona. |
| MXPA05002914A (es) | 2002-09-17 | 2005-05-27 | Pharmacia Corp | Moduladores de los receptores x hepaticos aromaticos. |
| WO2004058175A2 (en) | 2002-12-23 | 2004-07-15 | Irm Llc | Novel use of liver x receptor agonists |
| US20050009837A1 (en) | 2003-05-20 | 2005-01-13 | City Of Hope | Modulators of lipid metabolism and methods of use |
| JP2005128010A (ja) * | 2003-10-03 | 2005-05-19 | Takeda Chem Ind Ltd | インスリン抵抗性改善剤のスクリーニング方法 |
| RU2006124843A (ru) | 2003-12-12 | 2008-01-20 | Уайт (Us) | Хинолины, пригодные для лечения сердечно-сосудистого заболевания |
| JP2008509138A (ja) | 2004-08-03 | 2008-03-27 | ワイス | 心臓血管疾患の治療に有用なインダゾール類 |
| BRPI0716833A2 (pt) | 2006-09-19 | 2013-11-05 | Wyeth Corp | Uso de agonistas de lxr para o tratamento de osteoartrite |
| US9149492B2 (en) | 2008-10-08 | 2015-10-06 | Trustees Of Dartmouth College | Method for selectively inhibiting ACAT1 in the treatment of alzheimer's disease |
| JP2012516150A (ja) * | 2009-01-28 | 2012-07-19 | ザ メディカル リサーチ,インフラストラクチュア,アンド ヘルス サービシーズ ファンド オブ ザ テル アビブ メディカル センター | 炎症性疾患、自己免疫疾患及び循環器疾患におけるエオタキシン−2(ccl24)阻害剤 |
| JP5719340B2 (ja) | 2009-03-20 | 2015-05-20 | レティーナ インプラント アーゲー | 能動型網膜インプラント |
| WO2013056232A2 (en) | 2011-10-13 | 2013-04-18 | Case Western Reserve University | Rxr agonists compounds and methods |
| MX352727B (es) | 2011-12-13 | 2017-12-06 | Dartmouth College | Tratamiento de trastorno autoinmune al usar agonistas de rxr. |
| WO2015038585A1 (en) | 2013-09-11 | 2015-03-19 | Trustees Of Dartmouth College | Method for selectively inhibiting acat1 in the treatment of alzheimer's disease |
| US10286000B2 (en) | 2013-10-25 | 2019-05-14 | St. Jude Children's Research Hospital, Inc. | Retinoid X receptor-gamma agonists and retinoid X receptor-alpha antagonists for treatment of cancer |
| US10100308B2 (en) | 2014-05-29 | 2018-10-16 | Trustees Of Dartmouth College | Method for selectively inhibiting ACAT1 in the treatment of neurodegenerative diseases |
| EP3177322A4 (en) * | 2014-08-08 | 2018-07-18 | Alector LLC | Anti-trem2 antibodies and methods of use thereof |
| CN107708696B (zh) | 2015-06-30 | 2021-05-28 | 国立大学法人冈山大学 | 炎症性肠病的预防或治疗用药剂 |
| WO2017058866A1 (en) | 2015-09-28 | 2017-04-06 | Precision Immune, Inc. | Anti-trem2 antibodies and uses thereof |
| AU2016334051B2 (en) | 2015-10-06 | 2023-10-26 | Alector Llc | Anti-TREM2 antibodies and methods of use thereof |
| EP3368160B1 (en) | 2015-10-31 | 2023-05-17 | IO Therapeutics, Inc. | Treatment of nervous system disorders using thyroid hormone neutral doses of rxr agonists |
| US20190367623A1 (en) * | 2017-01-17 | 2019-12-05 | Yeda Research And Development Co. Ltd. | Methods of treating neurodegenerative diseases by inducing disease-associated microglia (dam) cells |
| JOP20190248A1 (ar) * | 2017-04-21 | 2019-10-20 | Amgen Inc | بروتينات ربط مولد ضد trem2 واستخداماته |
| BR112019022752A2 (pt) | 2017-08-03 | 2020-05-19 | Alector Llc | anticorpos anti-trem2 e métodos de uso dos mesmos |
| WO2019118513A1 (en) | 2017-12-12 | 2019-06-20 | Pionyr Immunotherapeutics, Inc. | Anti-trem2 antibodies and related methods |
-
2019
- 2019-11-26 CN CN201980089105.XA patent/CN113302206A/zh active Pending
- 2019-11-26 WO PCT/US2019/063427 patent/WO2020112889A2/en not_active Ceased
- 2019-11-26 US US17/296,506 patent/US20230132366A9/en active Pending
- 2019-11-26 MA MA054296A patent/MA54296A/fr unknown
- 2019-11-26 EP EP19824429.5A patent/EP3887401A2/en active Pending
- 2019-11-26 CA CA3120970A patent/CA3120970A1/en active Pending
- 2019-11-26 JP JP2021528981A patent/JP7607559B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020112889A2 (en) | 2020-06-04 |
| JP2022513114A (ja) | 2022-02-07 |
| CN113302206A (zh) | 2021-08-24 |
| WO2020112889A3 (en) | 2020-07-30 |
| CA3120970A1 (en) | 2020-06-04 |
| WO2020112889A9 (en) | 2021-06-10 |
| JP7607559B2 (ja) | 2024-12-27 |
| EP3887401A2 (en) | 2021-10-06 |
| US20230132366A9 (en) | 2023-04-27 |
| US20220025039A1 (en) | 2022-01-27 |
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