MA53177A - Apyrases solubilisées, méthodes et utilisation - Google Patents

Apyrases solubilisées, méthodes et utilisation

Info

Publication number
MA53177A
MA53177A MA053177A MA53177A MA53177A MA 53177 A MA53177 A MA 53177A MA 053177 A MA053177 A MA 053177A MA 53177 A MA53177 A MA 53177A MA 53177 A MA53177 A MA 53177A
Authority
MA
Morocco
Prior art keywords
apyrases
solubilized
methods
solubilized apyrases
Prior art date
Application number
MA053177A
Other languages
English (en)
Inventor
Agostino Cirillo
Hilmar Ebersbach
Boerje Haraldsson
Thomas Huber
Guido Junge
Regina Link
Max Warncke
Chao Zou
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA53177A publication Critical patent/MA53177A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y306/00—Hydrolases acting on acid anhydrides (3.6)
    • C12Y306/01—Hydrolases acting on acid anhydrides (3.6) in phosphorus-containing anhydrides (3.6.1)
    • C12Y306/01005—Apyrase (3.6.1.5), i.e. ATP diphosphohydrolase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MA053177A 2018-07-18 2019-07-17 Apyrases solubilisées, méthodes et utilisation MA53177A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP18184269 2018-07-18

Publications (1)

Publication Number Publication Date
MA53177A true MA53177A (fr) 2021-05-26

Family

ID=62985993

Family Applications (1)

Application Number Title Priority Date Filing Date
MA053177A MA53177A (fr) 2018-07-18 2019-07-17 Apyrases solubilisées, méthodes et utilisation

Country Status (25)

Country Link
US (1) US20220356455A1 (fr)
EP (1) EP3824079A1 (fr)
JP (2) JP7425784B2 (fr)
KR (1) KR20210035806A (fr)
CN (1) CN112424346B (fr)
AR (1) AR115790A1 (fr)
AU (1) AU2019306821B2 (fr)
BR (1) BR112021000586A2 (fr)
CA (1) CA3103684A1 (fr)
CL (1) CL2021000129A1 (fr)
CO (1) CO2021000210A2 (fr)
CR (1) CR20210021A (fr)
CU (1) CU20210008A7 (fr)
EA (1) EA202190057A1 (fr)
EC (1) ECSP21002804A (fr)
IL (1) IL280191A (fr)
JO (1) JOP20210008A1 (fr)
MA (1) MA53177A (fr)
MX (1) MX2021000542A (fr)
PE (1) PE20210185A1 (fr)
PH (1) PH12021550122A1 (fr)
SG (1) SG11202011776RA (fr)
UY (1) UY38299A (fr)
WO (1) WO2020016804A1 (fr)
ZA (1) ZA202007187B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230242965A1 (en) * 2020-05-28 2023-08-03 Charm Sciences, Inc. Methods and assemblies for sample analysis
TW202404627A (zh) 2022-07-29 2024-02-01 瑞士商諾華公司 使用cd39、重組cd39用於急性器官損傷的治療
WO2024023746A1 (fr) 2022-07-29 2024-02-01 Novartis Ag Production améliorée de variants de cd39

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2345382A1 (fr) 1998-10-16 2000-04-27 Immunex Corporation Inhibiteurs de l'activation et du recrutement plaquettaires
US20020002277A1 (en) * 1998-10-16 2002-01-03 Maliszewski Charles Richard Inhibitors of platelet activation and recruitment
US6867177B2 (en) 1999-08-13 2005-03-15 The Trustees Of Columbia University In The City Of New York CD39/ECTO-adpase as a treatment for thrombotic and ischemic disorders
US7247300B1 (en) 2002-11-07 2007-07-24 Apt Therapeutics, Inc. Therapeutic use of soluble CD39L3
US8551774B2 (en) 2005-03-17 2013-10-08 National Research Council Of Canada Expression vectors containing a truncated epstein barr nuclear antigen 1 lacking the Gly-Gly-Ala domain for enhanced transient gene expression
US8535662B2 (en) * 2010-01-13 2013-09-17 Apt Therapeutics, Inc. Apyrase therapy for bleeding conditions
ES2758505T3 (es) 2013-12-20 2020-05-05 Novartis Ag Células eucariotas novedosas y métodos para expresar de forma recombinante un producto de interés
US11203631B2 (en) 2013-12-20 2021-12-21 Novartis Ag Eukaryotic cells and methods for recombinantly expressing a product of interest

Also Published As

Publication number Publication date
CN112424346A (zh) 2021-02-26
TW202016299A (zh) 2020-05-01
AU2019306821B2 (en) 2022-09-29
ECSP21002804A (es) 2021-04-29
CU20210008A7 (es) 2021-08-06
MX2021000542A (es) 2021-03-29
JP7425784B2 (ja) 2024-01-31
CA3103684A1 (fr) 2020-01-23
AR115790A1 (es) 2021-02-24
JOP20210008A1 (ar) 2021-01-12
JP2021529550A (ja) 2021-11-04
EA202190057A1 (ru) 2021-08-24
US20220356455A1 (en) 2022-11-10
PE20210185A1 (es) 2021-02-02
IL280191A (en) 2021-03-01
CO2021000210A2 (es) 2021-01-18
JP2024023297A (ja) 2024-02-21
CR20210021A (es) 2021-03-23
CL2021000129A1 (es) 2021-08-20
BR112021000586A2 (pt) 2021-04-06
UY38299A (es) 2020-02-28
ZA202007187B (en) 2022-06-29
WO2020016804A1 (fr) 2020-01-23
SG11202011776RA (en) 2021-02-25
CN112424346B (zh) 2024-08-06
EP3824079A1 (fr) 2021-05-26
KR20210035806A (ko) 2021-04-01
AU2019306821A1 (en) 2020-12-24
PH12021550122A1 (en) 2021-09-27

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