MA53170A - Composés de sulfonylurée en tant qu'inhibiteurs de l'activité de l'interleukine 1 - Google Patents
Composés de sulfonylurée en tant qu'inhibiteurs de l'activité de l'interleukine 1Info
- Publication number
- MA53170A MA53170A MA053170A MA53170A MA53170A MA 53170 A MA53170 A MA 53170A MA 053170 A MA053170 A MA 053170A MA 53170 A MA53170 A MA 53170A MA 53170 A MA53170 A MA 53170A
- Authority
- MA
- Morocco
- Prior art keywords
- interleukin
- activity inhibitors
- sulphonylurea compounds
- sulphonylurea
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862701358P | 2018-07-20 | 2018-07-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA53170A true MA53170A (fr) | 2021-05-26 |
Family
ID=67515207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA053170A MA53170A (fr) | 2018-07-20 | 2019-07-19 | Composés de sulfonylurée en tant qu'inhibiteurs de l'activité de l'interleukine 1 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US11560391B2 (fr) |
| EP (1) | EP3823726A1 (fr) |
| JP (1) | JP7411631B2 (fr) |
| KR (1) | KR20210034588A (fr) |
| CN (1) | CN112437683A (fr) |
| AR (1) | AR117617A1 (fr) |
| AU (1) | AU2019305095A1 (fr) |
| BR (1) | BR112021001012A2 (fr) |
| CA (1) | CA3104199A1 (fr) |
| CL (1) | CL2021000152A1 (fr) |
| CO (1) | CO2021000817A2 (fr) |
| CR (1) | CR20210024A (fr) |
| IL (1) | IL280139A (fr) |
| MA (1) | MA53170A (fr) |
| MX (1) | MX2021000660A (fr) |
| PE (1) | PE20211049A1 (fr) |
| PH (1) | PH12020552155A1 (fr) |
| SG (1) | SG11202012159TA (fr) |
| TW (1) | TW202019937A (fr) |
| WO (1) | WO2020018970A1 (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201837021A (zh) | 2017-01-23 | 2018-10-16 | 美商傑庫爾醫療股份有限公司 | 作為介白素-1活性抑制劑之化合物 |
| WO2019034693A1 (fr) | 2017-08-15 | 2019-02-21 | Inflazome Limited | Sulfonylurées et sulfonylthiourées utilisés en tant qu'inhibiteurs de nlrp3 |
| AU2018317798A1 (en) | 2017-08-15 | 2020-02-13 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as NLRP |
| UY37848A (es) | 2017-08-15 | 2019-03-29 | Inflazome Ltd | Sulfonilureas y sulfoniltioureas útiles como inhibidores de nlrp3 |
| EP3707134A1 (fr) | 2017-11-09 | 2020-09-16 | Inflazome Limited | Nouveaux composés de sulfonamide carboxamide |
| WO2019166619A1 (fr) | 2018-03-02 | 2019-09-06 | Inflazome Limited | Nouveaux composés |
| US20220378801A1 (en) | 2019-06-21 | 2022-12-01 | Ac Immune Sa | Novel compounds |
| MX2022005732A (es) | 2019-11-12 | 2022-06-09 | Chengdu Baiyu Pharmaceutical Co Ltd | Derivado de amida y metodo de preparacion para el mismo y uso del mismo en medicina. |
| IL299084A (en) | 2020-06-19 | 2023-02-01 | Ac Immune Sa | History of dihydrooxazole and thiourea or urea modulating the NLRP3 inflammasome pathway |
| CN118541366A (zh) | 2021-12-22 | 2024-08-23 | Ac免疫有限公司 | 二氢噁唑衍生物化合物 |
| AU2023221635A1 (en) * | 2022-02-21 | 2024-09-12 | Viva Star Biosciences (Suzhou) Co., Ltd. | Novel bicyclic substituted sulfonylurea compounds as inhibitors of interleukin- 1 activity |
| US20240034735A1 (en) | 2022-07-14 | 2024-02-01 | Ac Immune Sa | Novel compounds |
| WO2024023266A1 (fr) | 2022-07-28 | 2024-02-01 | Ac Immune Sa | Nouveaux composés |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5216026A (en) | 1990-07-17 | 1993-06-01 | Eli Lilly And Company | Antitumor compositions and methods of treatment |
| TR199901816T2 (xx) * | 1997-01-29 | 1999-11-22 | Pfizer Inc | S�lfonil �re t�revleri, bunlar�n interl�kin-1 aktivitesinin kontrol�nde kullan�mlar�. |
| EP1214087A1 (fr) | 1999-09-14 | 2002-06-19 | Pfizer Products Inc. | Traitement combine au moyen de il-1ra et de composes de diarylsulfonyluree |
| AU2002341321A1 (en) | 2001-11-30 | 2003-06-10 | Pfizer Products Inc. | Combination of an il-1/18 inhibitor with a tnf inhibitor for the treatment of inflammation |
| CA2789665C (fr) * | 2010-02-22 | 2020-06-16 | Raqualia Pharma Inc. | Utilisation d'antagonistes de recepteur ep4 dans le traitement de maladies mediees par il-23 |
| JPWO2013031931A1 (ja) | 2011-09-02 | 2015-03-23 | 協和発酵キリン株式会社 | ケモカイン受容体活性調節剤 |
| MD3259253T2 (ro) * | 2015-02-16 | 2020-06-30 | Univ Queensland | Sulfoniluree și compuși înrudiți și utilizări ale acestora |
| JP2019512009A (ja) * | 2016-02-16 | 2019-05-09 | ザ・ユニバーシティ・オブ・クイーンズランド | スルホニルウレアおよび関連化合物ならびにこれらの利用 |
| WO2017184604A1 (fr) | 2016-04-18 | 2017-10-26 | Ifm Therapeutics, Inc | Composés et compositions destinés au traitement d'états associés à une activité de nlrp |
| MA44729A (fr) | 2016-04-18 | 2021-05-12 | Novartis Ag | Composés et compositions pour traiter des états associés à une activité de nlrp |
| TW201837021A (zh) * | 2017-01-23 | 2018-10-16 | 美商傑庫爾醫療股份有限公司 | 作為介白素-1活性抑制劑之化合物 |
| US11840543B2 (en) | 2017-05-24 | 2023-12-12 | The University Of Queensland | Compounds and uses |
| ES2906280T3 (es) | 2017-07-07 | 2022-04-18 | Inflazome Ltd | Nuevos compuestos de sulfonamida carboxamida |
| US11370776B2 (en) | 2017-07-07 | 2022-06-28 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors |
| EP3668840A1 (fr) | 2017-08-15 | 2020-06-24 | Inflazome Limited | Nouveaux composés de sulfonamide carboxamide |
| US20200361895A1 (en) | 2017-08-15 | 2020-11-19 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
| AU2018317798A1 (en) | 2017-08-15 | 2020-02-13 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as NLRP |
| KR20200041337A (ko) | 2017-08-15 | 2020-04-21 | 인플라좀 리미티드 | 신규한 설폰아마이드 카복스아마이드 화합물 |
| UY37848A (es) | 2017-08-15 | 2019-03-29 | Inflazome Ltd | Sulfonilureas y sulfoniltioureas útiles como inhibidores de nlrp3 |
| WO2019034693A1 (fr) | 2017-08-15 | 2019-02-21 | Inflazome Limited | Sulfonylurées et sulfonylthiourées utilisés en tant qu'inhibiteurs de nlrp3 |
| EP3668862A1 (fr) | 2017-08-15 | 2020-06-24 | Inflazome Limited | Nouveaux composés de sulfonamide carboxamide |
| WO2019043610A1 (fr) | 2017-08-31 | 2019-03-07 | Cadila Healthcare Limited | Nouveaux dérivés de sulfonylurées substitués |
| WO2019092172A1 (fr) | 2017-11-09 | 2019-05-16 | Inflazome Limited | Nouveaux composés de sulfonamide carboxamide |
| EP3707134A1 (fr) | 2017-11-09 | 2020-09-16 | Inflazome Limited | Nouveaux composés de sulfonamide carboxamide |
| WO2019092171A1 (fr) | 2017-11-09 | 2019-05-16 | Inflazome Limited | Nouveaux composés de sulfonamide carboxamide |
| GB201721185D0 (en) | 2017-12-18 | 2018-01-31 | Nodthera Ltd | Sulphonyl urea derivatives |
| WO2019166619A1 (fr) | 2018-03-02 | 2019-09-06 | Inflazome Limited | Nouveaux composés |
| GB201803394D0 (en) | 2018-03-02 | 2018-04-18 | Inflazome Ltd | Novel compounds |
| GB201803393D0 (en) | 2018-03-02 | 2018-04-18 | Inflazome Ltd | Novel compounds |
| GB201806578D0 (en) | 2018-04-23 | 2018-06-06 | Inflazome Ltd | Novel compound |
| CN112654350A (zh) | 2018-07-03 | 2021-04-13 | 诺华股份有限公司 | 使用nlrp3拮抗剂治疗对tnf抑制剂有抗性的受试者或针对所述患者选择治疗的方法 |
| EP3817817A1 (fr) | 2018-07-03 | 2021-05-12 | Novartis AG | Modulateurs de nlrp |
| JP7320595B2 (ja) | 2018-07-20 | 2023-08-03 | エフ． ホフマン－ラ ロシュ アーゲー | インターロイキン－１活性の阻害剤としてのスルホンイミドアミド化合物 |
| TWI811400B (zh) | 2018-07-20 | 2023-08-11 | 德商歌林達有限公司 | 經進一步取代之三唑并喹噁啉衍生物 |
| GB201902327D0 (en) | 2019-02-20 | 2019-04-03 | Inflazome Ltd | Novel compounds |
| CN112672995A (zh) | 2018-08-15 | 2021-04-16 | 英夫拉索姆有限公司 | 新型磺酰胺脲化合物 |
| GB201817038D0 (en) | 2018-10-19 | 2018-12-05 | Inflazome Ltd | Novel processes |
| US20230011652A1 (en) | 2018-10-24 | 2023-01-12 | Novartis Ag | Compounds and compositions for treating conditions associated with nlrp activity |
| GB201819083D0 (en) | 2018-11-23 | 2019-01-09 | Inflazome Ltd | Novel compounds |
| WO2020154321A1 (fr) | 2019-01-22 | 2020-07-30 | Novartis Inflammasome Research, Inc. | Composés et compositions pour traiter des états associés à une activité de nlrp |
| WO2021002887A1 (fr) | 2019-07-02 | 2021-01-07 | Novartis Inflammasome Research, Inc. | Antagonistes de nlrp3 ciblant l'intestin et leur utilisation en thérapie |
-
2019
- 2019-07-19 CA CA3104199A patent/CA3104199A1/fr active Pending
- 2019-07-19 MX MX2021000660A patent/MX2021000660A/es unknown
- 2019-07-19 JP JP2021502998A patent/JP7411631B2/ja active Active
- 2019-07-19 MA MA053170A patent/MA53170A/fr unknown
- 2019-07-19 AU AU2019305095A patent/AU2019305095A1/en not_active Abandoned
- 2019-07-19 BR BR112021001012-2A patent/BR112021001012A2/pt not_active Application Discontinuation
- 2019-07-19 CN CN201980048411.9A patent/CN112437683A/zh active Pending
- 2019-07-19 WO PCT/US2019/042703 patent/WO2020018970A1/fr active Application Filing
- 2019-07-19 PE PE2021000074A patent/PE20211049A1/es unknown
- 2019-07-19 KR KR1020217001676A patent/KR20210034588A/ko unknown
- 2019-07-19 EP EP19749134.3A patent/EP3823726A1/fr active Pending
- 2019-07-19 SG SG11202012159TA patent/SG11202012159TA/en unknown
- 2019-07-19 CR CR20210024A patent/CR20210024A/es unknown
- 2019-07-22 AR ARP190102054A patent/AR117617A1/es unknown
- 2019-07-22 TW TW108125890A patent/TW202019937A/zh unknown
-
2020
- 2020-12-14 PH PH12020552155A patent/PH12020552155A1/en unknown
-
2021
- 2021-01-12 IL IL280139A patent/IL280139A/en unknown
- 2021-01-15 US US17/150,380 patent/US11560391B2/en active Active
- 2021-01-19 CL CL2021000152A patent/CL2021000152A1/es unknown
- 2021-01-26 CO CONC2021/0000817A patent/CO2021000817A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL280139A (en) | 2021-03-01 |
| JP2021530536A (ja) | 2021-11-11 |
| CN112437683A (zh) | 2021-03-02 |
| AU2019305095A1 (en) | 2020-12-17 |
| KR20210034588A (ko) | 2021-03-30 |
| EP3823726A1 (fr) | 2021-05-26 |
| CL2021000152A1 (es) | 2021-07-09 |
| US20210261568A1 (en) | 2021-08-26 |
| AR117617A1 (es) | 2021-08-18 |
| WO2020018970A1 (fr) | 2020-01-23 |
| PE20211049A1 (es) | 2021-06-04 |
| PH12020552155A1 (en) | 2021-07-05 |
| CA3104199A1 (fr) | 2020-01-23 |
| TW202019937A (zh) | 2020-06-01 |
| JP7411631B2 (ja) | 2024-01-11 |
| CO2021000817A2 (es) | 2021-02-17 |
| MX2021000660A (es) | 2021-03-25 |
| US11560391B2 (en) | 2023-01-24 |
| BR112021001012A2 (pt) | 2021-04-20 |
| CR20210024A (es) | 2021-02-22 |
| SG11202012159TA (en) | 2021-01-28 |
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