MA51999A - Nouvelle formulation pharmaceutique comprenant des antagonistes doubles des récepteurs nk-1/nk-3 - Google Patents
Nouvelle formulation pharmaceutique comprenant des antagonistes doubles des récepteurs nk-1/nk-3Info
- Publication number
- MA51999A MA51999A MA051999A MA51999A MA51999A MA 51999 A MA51999 A MA 51999A MA 051999 A MA051999 A MA 051999A MA 51999 A MA51999 A MA 51999A MA 51999 A MA51999 A MA 51999A
- Authority
- MA
- Morocco
- Prior art keywords
- receptor
- pharmaceutical formulation
- formulation including
- new pharmaceutical
- including dual
- Prior art date
Links
- 102000002002 Neurokinin-1 Receptors Human genes 0.000 title 1
- 108010040718 Neurokinin-1 Receptors Proteins 0.000 title 1
- 102000002003 Neurokinin-3 Receptors Human genes 0.000 title 1
- 108010040716 Neurokinin-3 Receptors Proteins 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 230000009977 dual effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862642622P | 2018-03-14 | 2018-03-14 | |
| PCT/EP2019/056303 WO2019175253A1 (fr) | 2018-03-14 | 2019-03-13 | Nouvelle formulation pharmaceutique comprenant des antagonistes doubles des récepteurs nk-1/nk-3 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MA51999A true MA51999A (fr) | 2021-01-20 |
| MA51999B1 MA51999B1 (fr) | 2024-02-29 |
Family
ID=65817992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA51999A MA51999B1 (fr) | 2018-03-14 | 2019-03-13 | Nouvelle formulation pharmaceutique comprenant deux antagonistes recepteurs de nk-1/nk-3. |
Country Status (28)
| Country | Link |
|---|---|
| US (5) | US10774091B2 (fr) |
| EP (1) | EP3765024B1 (fr) |
| JP (1) | JP7433252B2 (fr) |
| KR (1) | KR20200139138A (fr) |
| CN (1) | CN112292132A (fr) |
| AU (1) | AU2019233606A1 (fr) |
| BR (1) | BR112020017388A2 (fr) |
| CA (1) | CA3092238A1 (fr) |
| CL (1) | CL2020002350A1 (fr) |
| CO (1) | CO2020011262A2 (fr) |
| CR (1) | CR20200385A (fr) |
| DK (1) | DK3765024T3 (fr) |
| EA (1) | EA202092131A1 (fr) |
| EC (1) | ECSP20057488A (fr) |
| FI (1) | FI3765024T3 (fr) |
| GE (1) | GEP20237503B (fr) |
| HR (1) | HRP20240120T1 (fr) |
| IL (1) | IL276959B1 (fr) |
| JO (1) | JOP20200227A1 (fr) |
| LT (1) | LT3765024T (fr) |
| MA (1) | MA51999B1 (fr) |
| MX (2) | MX2020009438A (fr) |
| PE (1) | PE20210395A1 (fr) |
| PH (1) | PH12020551457A1 (fr) |
| PT (1) | PT3765024T (fr) |
| RS (1) | RS65257B1 (fr) |
| SG (1) | SG11202008226YA (fr) |
| WO (1) | WO2019175253A1 (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112019005246A2 (pt) | 2016-09-18 | 2019-06-04 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | composto com a fórmula i, composto com a fórmula ii, composto com a fórmula iii, composição farmacêutica, método de tratamento de câncer |
| SG11202008854TA (en) | 2018-03-14 | 2020-10-29 | H Lee Moffitt Cancer Center And Research Institute Inc | Yap1 inhibitors that target the interaction of yap1 with oct4 |
| SG11202008226YA (en) | 2018-03-14 | 2020-09-29 | Kandy Therapeutics Ltd | Novel pharmaceutical formulation comprising dual nk-1/nk-3 receptor antagonists |
| KR20220101090A (ko) | 2019-11-15 | 2022-07-19 | 칸디 테라퓨틱스 리미티드 | Nt-814의 핵심 중간체인 6-클로로-4-(4-플루오로-2-메틸페닐)피리딘-3-아민의 새로운 화학적 제조 방법 |
| KR102484687B1 (ko) * | 2022-03-04 | 2023-01-05 | (주)씨앤엘디 | 페노피브레이트를 포함하는 이상지질혈증의 예방 또는 치료용 약학 조성물 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3097618A (en) | 1960-12-01 | 1963-07-16 | Raymond Bag Corp | Manufacture of multi-wall bag having heat-sealed liner |
| DE4322826A1 (de) * | 1993-07-08 | 1995-01-12 | Galenik Labor Freiburg Gmbh | Pharmazeutisches Präparat |
| GB9907571D0 (en) | 1999-04-06 | 1999-05-26 | Zeneca Ltd | Compounds |
| DE60129562T2 (de) | 2000-06-12 | 2008-04-17 | The University Of Rochester | Methode zur Behandlung von Hitzewallungen durch Verwendung eines Tachykinin-Rezeptor-Antagonisten |
| EP1192952A3 (fr) | 2000-09-28 | 2003-03-26 | Pfizer Products Inc. | Composition pour le traitement de la dépression et de l'anxieté contenant un antagoniste du recepteur NK-3 et un antagoniste du récepteur NK-1 |
| WO2002089802A2 (fr) | 2001-05-08 | 2002-11-14 | Schering Corporation | Utilisation d'antagonistes de recepteur de neurokinine pour le traitement de maladies liees aux androgenes |
| ES2310260T3 (es) | 2002-12-23 | 2009-01-01 | Janssen Pharmaceutica Nv | Derivados sustituidos de 4-(4-piperidin-4-il-piperazin-1-il)-azepan y su uso como antagonistas de la neuroquinina. |
| JO2696B1 (en) | 2002-12-23 | 2013-03-03 | شركة جانسين فارماسوتيكا ان. في | Derivatives of 1-piperdine-4-yl-4-biprolidine-3-yl-piperazine substituted and used as quinine antagonists |
| US7525659B2 (en) | 2003-01-15 | 2009-04-28 | Negevtech Ltd. | System for detection of water defects |
| JP4490421B2 (ja) | 2003-07-03 | 2010-06-23 | エフ．ホフマン−ラ ロシュ アーゲー | 統合失調症を処置するデュアルｎｋ１／ｎｋ３アンタゴニスト |
| JO2676B1 (en) | 2004-04-06 | 2012-06-17 | جانسين فارماسوتيكا ان. في | Derivatives of second-aza-spiro- (5,4) -dikan and their use as antihistamines |
| JO2525B1 (en) | 2004-04-08 | 2010-03-17 | شركة جانسين فارماسوتيكا ان. في | Derived 4-alkyl-and-4-canoelperidine derivatives and their use as anti-neroquin |
| BRPI0510951A (pt) | 2004-05-12 | 2007-11-20 | Pfizer Prod Inc | derivados de piperidina como antagonistas de nk1 e nk3 |
| DE102004033902A1 (de) | 2004-07-14 | 2006-02-16 | Zentaris Gmbh | Neue Tetrahydrocarbazolderivate mit verbesserter biologischer Wirkung und verbesserter Löslichkeit als Liganden für G-Protein gekoppelte Rezeptoren (GPCR's) |
| WO2006013205A1 (fr) | 2004-08-04 | 2006-02-09 | Solvay Pharmaceuticals B.V. | Antagonistes des récepteurs de la neurokinine-1 pour le traitement des états sensibles à une élévation de la testostérone |
| US20060030600A1 (en) | 2004-08-06 | 2006-02-09 | Patrick Schnider | Dual NK1/NK3 receptor antagonists for the treatment of schizophrenia |
| AR058805A1 (es) * | 2005-09-09 | 2008-02-27 | Smithkline Beecham Corp | Derivados biciclicos de piridina utiles como agentes antipsicoticos |
| JP5203449B2 (ja) | 2007-04-20 | 2013-06-05 | エフ．ホフマン−ラ ロシュ アーゲー | 二重ｎｋ１／ｎｋ３受容体アンタゴニストとしてのピロリジン誘導体 |
| GB0814340D0 (en) | 2008-08-05 | 2008-09-10 | Smithkline Beecham Corp | Anhydrous crystol form fo a pyridine derivative |
| US8796269B2 (en) * | 2009-08-27 | 2014-08-05 | Nerre Therapeutics Limited | Crystalline 2-(3,5-Bis(trifluoromethyl)phenyl)-N-(4-(4-fluoro-2-methylphenyl)-6-((7S,9aS)-7-(hydroxymethyl)hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl)pyridin-3-yl)-N,2-dimethyl-propanamide of the formula (I), their use in therapy, and process for the preparation of the same |
| US8487102B2 (en) | 2010-04-20 | 2013-07-16 | Hoffmann-La Roche Inc. | Pyrrazolopyridine compounds as dual NK1/NK3 receptor antagonists |
| US9446029B2 (en) | 2010-07-27 | 2016-09-20 | Colorado State University Research Foundation | Use of NK-1 receptor antagonists in management of visceral pain |
| ES2376564B1 (es) | 2010-08-12 | 2013-01-24 | Manuel Vicente Salinas Martín | Utilización de anticuerpos contra los receptores nk1, nk2 y/o nk3, para producir apoptosis en las células tumorales y modificar el estroma, la inmunidad y la vascularización intra y peritumorales, como tratamiento del cáncer. |
| GB2488788B (en) * | 2011-03-07 | 2013-07-10 | Natco Pharma Ltd | Oral formulation of phenylaminopyrymidine compound with enhanced bioavailability and pharmacological response |
| CA2857694A1 (fr) | 2011-12-02 | 2013-06-06 | Glaxosmithkline Intellectual Property (No.2) Limited | Inhibiteurs de peptide deformylase |
| KR101739820B1 (ko) | 2012-03-28 | 2017-05-25 | 주식회사유한양행 | 레바프라잔 또는 그의 염을 함유하는 비수성 액체 형태의 경구투여용 약학 조성물 |
| WO2014089019A1 (fr) | 2012-12-03 | 2014-06-12 | University Of Washington Through Its Center For Commercialization | Procédés et compositions pour le traitement de symptômes vasomoteurs |
| GB201315846D0 (en) | 2013-09-05 | 2013-10-23 | Imp Innovations Ltd | Method for treating or preventing hot flushes |
| BR112017024852B1 (pt) | 2015-05-18 | 2023-10-31 | KaNDy Therapeutics Limited | Usos de um composto antagonista do receptor nk-1/nk-3 duplo e de uma composição farmacêutica compreendendo dito composto para o tratamento de sintomas vasomotores associados com menopausa |
| SG11202008226YA (en) | 2018-03-14 | 2020-09-29 | Kandy Therapeutics Ltd | Novel pharmaceutical formulation comprising dual nk-1/nk-3 receptor antagonists |
| KR20220101090A (ko) | 2019-11-15 | 2022-07-19 | 칸디 테라퓨틱스 리미티드 | Nt-814의 핵심 중간체인 6-클로로-4-(4-플루오로-2-메틸페닐)피리딘-3-아민의 새로운 화학적 제조 방법 |
-
2019
- 2019-03-13 SG SG11202008226YA patent/SG11202008226YA/en unknown
- 2019-03-13 LT LTEPPCT/EP2019/056303T patent/LT3765024T/lt unknown
- 2019-03-13 CA CA3092238A patent/CA3092238A1/fr active Pending
- 2019-03-13 WO PCT/EP2019/056303 patent/WO2019175253A1/fr active Application Filing
- 2019-03-13 EA EA202092131A patent/EA202092131A1/ru unknown
- 2019-03-13 PE PE2020001406A patent/PE20210395A1/es unknown
- 2019-03-13 US US16/351,659 patent/US10774091B2/en active Active
- 2019-03-13 MX MX2020009438A patent/MX2020009438A/es unknown
- 2019-03-13 AU AU2019233606A patent/AU2019233606A1/en active Pending
- 2019-03-13 CR CR20200385A patent/CR20200385A/es unknown
- 2019-03-13 JP JP2020572615A patent/JP7433252B2/ja active Active
- 2019-03-13 MA MA51999A patent/MA51999B1/fr unknown
- 2019-03-13 DK DK19711866.4T patent/DK3765024T3/da active
- 2019-03-13 HR HRP20240120TT patent/HRP20240120T1/hr unknown
- 2019-03-13 IL IL276959A patent/IL276959B1/en unknown
- 2019-03-13 KR KR1020207026436A patent/KR20200139138A/ko unknown
- 2019-03-13 JO JOP/2020/0227A patent/JOP20200227A1/ar unknown
- 2019-03-13 FI FIEP19711866.4T patent/FI3765024T3/fi active
- 2019-03-13 CN CN201980019147.6A patent/CN112292132A/zh active Pending
- 2019-03-13 BR BR112020017388-6A patent/BR112020017388A2/pt unknown
- 2019-03-13 PT PT197118664T patent/PT3765024T/pt unknown
- 2019-03-13 EP EP19711866.4A patent/EP3765024B1/fr active Active
- 2019-03-13 RS RS20240167A patent/RS65257B1/sr unknown
- 2019-03-13 GE GEAP201915464A patent/GEP20237503B/en unknown
-
2020
- 2020-08-04 US US16/984,961 patent/US11591346B2/en active Active
- 2020-08-04 US US16/985,087 patent/US11787820B2/en active Active
- 2020-09-10 MX MX2022005706A patent/MX2022005706A/es unknown
- 2020-09-11 CL CL2020002350A patent/CL2020002350A1/es unknown
- 2020-09-11 PH PH12020551457A patent/PH12020551457A1/en unknown
- 2020-09-11 CO CONC2020/0011262A patent/CO2020011262A2/es unknown
- 2020-09-14 EC ECSENADI202057488A patent/ECSP20057488A/es unknown
-
2023
- 2023-01-13 US US18/097,046 patent/US11767328B2/en active Active
- 2023-07-31 US US18/228,593 patent/US20230382922A1/en active Pending
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