MA50101A - Agents de modulation des fonctions de la bêta-caténine et méthodes associées - Google Patents
Agents de modulation des fonctions de la bêta-caténine et méthodes associéesInfo
- Publication number
- MA50101A MA50101A MA050101A MA50101A MA50101A MA 50101 A MA50101 A MA 50101A MA 050101 A MA050101 A MA 050101A MA 50101 A MA50101 A MA 50101A MA 50101 A MA50101 A MA 50101A
- Authority
- MA
- Morocco
- Prior art keywords
- agents
- related methods
- modulating beta
- catenin functions
- catenin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/03—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K4/00—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762555519P | 2017-09-07 | 2017-09-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA50101A true MA50101A (fr) | 2020-07-15 |
Family
ID=65635271
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA050101A MA50101A (fr) | 2017-09-07 | 2018-09-07 | Agents de modulation des fonctions de la bêta-caténine et méthodes associées |
Country Status (14)
Country | Link |
---|---|
US (2) | US11198713B2 (fr) |
EP (1) | EP3678683A4 (fr) |
JP (1) | JP2020533413A (fr) |
KR (1) | KR20200064075A (fr) |
CN (1) | CN111372942A (fr) |
AU (1) | AU2018329956A1 (fr) |
BR (1) | BR112020004555A2 (fr) |
CA (1) | CA3074838A1 (fr) |
EA (1) | EA202090513A1 (fr) |
IL (1) | IL273015A (fr) |
MA (1) | MA50101A (fr) |
MX (1) | MX2020002435A (fr) |
SG (1) | SG11202001162TA (fr) |
WO (1) | WO2019051327A2 (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2018329956A1 (en) | 2017-09-07 | 2020-08-20 | Fog Pharmaceuticals, Inc. | Agents modulating beta-catenin functions and methods thereof |
CN113557030A (zh) | 2018-11-21 | 2021-10-26 | 恩多梅特生物科学公司 | 用于治疗子宫内膜异位症的组合物和方法 |
WO2021041895A1 (fr) * | 2019-08-30 | 2021-03-04 | Ohio State Innovation Foundation | Ligands de bêta-caténine agrafés |
JP2023535026A (ja) * | 2020-07-22 | 2023-08-15 | フォグ ファーマシューティカルズ, インコーポレイテッド | ステープルペプチドおよびその方法 |
JP2024522368A (ja) * | 2021-06-08 | 2024-06-18 | フォグ ファーマシューティカルズ, インコーポレイテッド | ステープルペプチドおよびその方法 |
Family Cites Families (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0360390A1 (fr) | 1988-07-25 | 1990-03-28 | Glaxo Group Limited | Dérivés de spirolactames |
US5808146A (en) | 1995-11-09 | 1998-09-15 | Emory University | Amino acid analogs for tumor imaging |
US6444425B1 (en) | 1999-04-02 | 2002-09-03 | Corixa Corporation | Compounds for therapy and diagnosis of lung cancer and methods for their use |
US7192713B1 (en) | 1999-05-18 | 2007-03-20 | President And Fellows Of Harvard College | Stabilized compounds having secondary structure motifs |
AU1207301A (en) | 1999-10-15 | 2001-04-30 | Avatar Medical, Llc | Stabilized proteins |
US20080220441A1 (en) | 2001-05-16 | 2008-09-11 | Birnbaum Eva R | Advanced drug development and manufacturing |
US6822073B2 (en) | 2001-12-20 | 2004-11-23 | Kimberly-Clark Worldwide, Inc. | Modular peptide-based reagent |
EP1648873A4 (fr) | 2003-03-20 | 2008-06-25 | Neuren Pharmaceuticals Ltd | Composes macrocycliques neuroprotecteurs et procedes d'utilisation de ces composes |
WO2004093798A2 (fr) | 2003-04-18 | 2004-11-04 | Enanta Pharmaceuticals, Inc. | Composes macrocycliques de quinoxalinyle inhibant les serine proteases de l'hepatite c |
US7348434B2 (en) | 2003-08-08 | 2008-03-25 | Antony Bigot | 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them |
EP1680443B9 (fr) | 2003-11-05 | 2014-09-03 | Dana-Farber Cancer Institute, Inc. | Peptides stabilises structures en helice alpha et leurs utilisations |
JP2008510692A (ja) | 2004-08-20 | 2008-04-10 | ノボ ノルディスク アクティーゼルスカブ | 薬学的に活性なインスリン受容体調節分子 |
JP2008522954A (ja) | 2004-08-20 | 2008-07-03 | フィロジカ リミテッド | c−Jun二量化のペプチド阻害剤及びその使用 |
MX2007007259A (es) | 2004-12-20 | 2007-08-14 | Sigma Tau Ind Farmaceuti | Inhibidores de homodimerizacion de myd88. |
GB0511771D0 (en) | 2005-06-09 | 2005-07-20 | Novartis Ag | Organic compounds |
EP2091552A4 (fr) | 2006-11-15 | 2010-01-06 | Dana Farber Cancer Inst Inc | Peptides maml stabilisés et leurs utilisations |
JP5649825B2 (ja) | 2007-01-31 | 2015-01-07 | デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド | 安定化させたp53ペプチドおよびその使用法 |
ES2430067T3 (es) | 2007-03-28 | 2013-11-18 | President And Fellows Of Harvard College | Polipéptidos cosidos |
EP2152294B1 (fr) | 2007-05-02 | 2017-07-26 | Dana-Farber Cancer Institute, Inc. | A bad bh3 domain peptides pour utilisation dans le traitement ou le retardement de l'apparition du diabète. |
WO2009020477A1 (fr) | 2007-08-06 | 2009-02-12 | Yale University | Protéines miniatures modifiées |
CA2700925C (fr) | 2007-09-26 | 2016-08-23 | Dana Farber Cancer Institute | Procedes et compositions pour moduler des polypeptides de la famille bcl-2 |
ES2629440T5 (es) | 2007-10-04 | 2020-11-20 | Zymogenetics Inc | zB7H6 miembro de la familia B7 y composiciones y métodos relacionados |
EP2247606B1 (fr) | 2008-01-23 | 2019-08-21 | Dana-Farber Cancer Institute, Inc. | Compositions et méthodes de traitement des infections virales |
WO2010011313A2 (fr) | 2008-07-23 | 2010-01-28 | President And Fellows Of Harvard College | Ligature de polypeptides agrafés |
CN102482336B (zh) | 2008-09-22 | 2015-05-06 | 爱勒让治疗公司 | 拟肽大环化合物 |
WO2010042225A2 (fr) | 2008-10-10 | 2010-04-15 | Dana Farber Cancer Institute | Modulateurs chimiques des polypeptides bax et bcl-2 pro-apoptotiques |
EP3549951A3 (fr) | 2008-12-09 | 2019-11-20 | Dana Farber Cancer Institute, Inc. | Procédés et compositions pour la modulation spécifique de mcl-1 |
EA021794B1 (ru) | 2008-12-10 | 2015-09-30 | Ачиллион Фармасьютикалз, Инк. | Циклические аналоги 4-амино-4-оксобутаноил пептидов, ингибиторы репликации вирусов |
EP2422201B1 (fr) | 2009-04-22 | 2015-04-22 | The Walter and Eliza Hall Institute of Medical Research | Structure de la region c terminale de la chaîne alpha du recepteur d'insuline et de la chaîne alpha du recepteur de facteur de croissance de type insuline |
US9175038B2 (en) | 2009-05-15 | 2015-11-03 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Peptide mimetic ligands of polo-like kinase 1 polo box domain and methods of use |
US9296805B2 (en) | 2009-06-18 | 2016-03-29 | Dana-Farber Cancer Institute, Inc. | Stabilized insulinotropic peptides and methods of use |
EP3698810A1 (fr) | 2009-06-18 | 2020-08-26 | Dana Farber Cancer Institute, Inc. | Compositions de peptides viraux structurés et procédés d'utilisation |
DE102009032902A1 (de) | 2009-07-10 | 2011-01-13 | Forschungsverbund Berlin E.V. | Induktion von α-Helix-Konformationen in Proteinen und Peptiden |
WO2011008260A2 (fr) | 2009-07-13 | 2011-01-20 | President And Fellows Of Harvard College | Peptides bifonctionnels insérés et leurs utilisations |
EP2528893B1 (fr) | 2010-01-29 | 2018-10-10 | Dana-Farber Cancer Institute, Inc. | Petites molécules pour la modulation de mcl-1 et procédés de modulation de la mort cellulaire, la division cellulaire, la différenciation cellulaire et procédés de traitement de troubles |
US8748570B2 (en) | 2010-05-25 | 2014-06-10 | Syngene Limited | Insulin analogues |
WO2012040459A2 (fr) | 2010-09-22 | 2012-03-29 | President And Fellows Of Harvard College | Peptides de ciblage de la béta-caténine et leurs utilisations |
JP2014502152A (ja) | 2010-11-12 | 2014-01-30 | ダナ ファーバー キャンサー インスティテュート,インコーポレイテッド | 癌の治療及び診断 |
WO2012082891A1 (fr) * | 2010-12-14 | 2012-06-21 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Inhibiteurs peptidiques synthétiques de la voie wnt |
BR112013015389A2 (pt) | 2010-12-22 | 2016-11-22 | Univ Indiana Res & Tech Corp | análogo de glucagon exibindo atividade de receptor gip |
CA2833171C (fr) | 2011-04-15 | 2021-08-31 | Loren D. Walensky | Ciblage d'une signalisation wnt deregulee dans le cancer a l'aide d'helices alpha de bcl-9 stabilisees |
US9487562B2 (en) | 2011-06-17 | 2016-11-08 | President And Fellows Of Harvard College | Stabilized polypeptides as regulators of RAB GTPase function |
JP2014520120A (ja) | 2011-06-17 | 2014-08-21 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 安定化した変異型mamlペプチドおよびその使用 |
EP3799871B1 (fr) | 2011-10-11 | 2024-02-28 | Dana Farber Cancer Institute, Inc. | Pyrazol-3-ones activant le bax pro-apoptotique |
EP2858661B1 (fr) | 2011-12-29 | 2020-04-22 | Dana-Farber Cancer Institute, Inc. | Hélices hybrides stabilisées antivirales |
AU2013235425B2 (en) | 2012-03-20 | 2017-09-21 | Dana Farber Cancer Institute, Inc. | Inhibition of MCL-1 and/or BFL-1/A1 |
US20150198619A1 (en) | 2012-09-25 | 2015-07-16 | The Walter And Eliza Hall Institute Of Medical Research | Structure of insulin in complex with n- and c-terminal regions of the insulin receptor alpha-chain |
DK2920197T3 (da) | 2012-09-26 | 2021-05-31 | Harvard College | Prolinlåste sammenhæftede peptider og anvendelser deraf |
WO2014055564A1 (fr) | 2012-10-01 | 2014-04-10 | President And Fellows Of Harvard College | Modulateurs stabilisés du récepteur de l'insuline polypeptidique |
US9493510B2 (en) | 2013-01-10 | 2016-11-15 | Noliva Therapeutics Llc | Peptidomimetic compounds |
SG10201700952XA (en) | 2013-03-13 | 2017-04-27 | Harvard College | Stapled and stitched polypeptides and uses thereof |
US10087215B2 (en) | 2013-03-15 | 2018-10-02 | Dana-Farber Cancer Institute, Inc. | Stabilized SOS1 peptides |
US10308926B2 (en) | 2013-03-15 | 2019-06-04 | Dana-Farber Cancer Institute, Inc. | Stablized EZH2 peptides |
US10106590B2 (en) | 2013-03-15 | 2018-10-23 | Dana-Farber Cancer Institute, Inc. | BH4 stabilized peptides and uses thereof |
US20160122405A1 (en) | 2013-06-06 | 2016-05-05 | President And Fellows Of Harvard College | Homeodomain fusion proteins and uses thereof |
US10227390B2 (en) | 2013-06-14 | 2019-03-12 | President And Fellows Of Harvard College | Stabilized polypeptide insulin receptor modulators |
EP3052520A4 (fr) | 2013-10-01 | 2017-12-06 | President and Fellows of Harvard College | Polypeptides stabilisés et utilisations de ces derniers |
US10533039B2 (en) | 2014-05-21 | 2020-01-14 | President And Fellows Of Harvard College | Ras inhibitory peptides and uses thereof |
AU2016232833A1 (en) | 2015-03-18 | 2017-10-12 | Dana-Farber Cancer Institute, Inc. | Selective Mcl-1 binding peptides |
JP6918712B2 (ja) | 2015-07-02 | 2021-08-11 | デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド | 安定化抗微生物性ペプチド |
US11078246B2 (en) | 2015-08-28 | 2021-08-03 | Dana-Farber Cancer Institute, Inc. | Peptides binding to Bfl-1 |
US20190002506A1 (en) | 2015-08-28 | 2019-01-03 | Dana-Farber Cancer Institute, Inc. | Stabilized peptides for covalent binding to target protein |
CN108883147B (zh) * | 2015-10-05 | 2023-04-11 | 北京佳诚生物医药科技开发有限公司 | 用于治疗异常Wnt信号传送的稳定化BCL9肽 |
WO2017147283A1 (fr) * | 2016-02-23 | 2017-08-31 | Dana-Farber Cancer Institute, Inc. | Procédé de génération de peptides de pénétration cellulaire agrafés qui sont dépourvus de propriétés de lyse membranaire non spécifique pour le ciblage thérapeutique |
AU2018329956A1 (en) | 2017-09-07 | 2020-08-20 | Fog Pharmaceuticals, Inc. | Agents modulating beta-catenin functions and methods thereof |
MX2021001943A (es) | 2018-08-20 | 2021-07-15 | Fog Pharmaceuticals Inc | Colecciones de péptidos, agentes peptídicos y métodos de uso de los mismos. |
WO2021119537A1 (fr) | 2019-12-11 | 2021-06-17 | Fog Pharmaceuticals, Inc. | Technologies utiles pour évaluer la perméabilité |
JP2023518413A (ja) | 2020-03-17 | 2023-05-01 | フォグ ファーマシューティカルズ, インコーポレイテッド | ヘリックス状ステープルペプチドおよびその使用 |
JP2023535026A (ja) | 2020-07-22 | 2023-08-15 | フォグ ファーマシューティカルズ, インコーポレイテッド | ステープルペプチドおよびその方法 |
EP4185284A1 (fr) | 2020-07-22 | 2023-05-31 | Fog Pharmaceuticals, Inc. | Acides aminés |
JP2024522368A (ja) | 2021-06-08 | 2024-06-18 | フォグ ファーマシューティカルズ, インコーポレイテッド | ステープルペプチドおよびその方法 |
-
2018
- 2018-09-07 AU AU2018329956A patent/AU2018329956A1/en not_active Abandoned
- 2018-09-07 US US16/645,407 patent/US11198713B2/en active Active
- 2018-09-07 EP EP18854947.1A patent/EP3678683A4/fr active Pending
- 2018-09-07 MX MX2020002435A patent/MX2020002435A/es unknown
- 2018-09-07 SG SG11202001162TA patent/SG11202001162TA/en unknown
- 2018-09-07 WO PCT/US2018/050102 patent/WO2019051327A2/fr unknown
- 2018-09-07 CA CA3074838A patent/CA3074838A1/fr active Pending
- 2018-09-07 BR BR112020004555-1A patent/BR112020004555A2/pt unknown
- 2018-09-07 MA MA050101A patent/MA50101A/fr unknown
- 2018-09-07 JP JP2020536712A patent/JP2020533413A/ja active Pending
- 2018-09-07 CN CN201880057772.5A patent/CN111372942A/zh active Pending
- 2018-09-07 EA EA202090513A patent/EA202090513A1/ru unknown
- 2018-09-07 KR KR1020207009023A patent/KR20200064075A/ko not_active Application Discontinuation
-
2020
- 2020-03-03 IL IL273015A patent/IL273015A/en unknown
-
2021
- 2021-11-03 US US17/518,247 patent/US11834482B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EA202090513A1 (ru) | 2020-08-24 |
BR112020004555A2 (pt) | 2020-09-24 |
SG11202001162TA (en) | 2020-03-30 |
US20220213154A1 (en) | 2022-07-07 |
WO2019051327A2 (fr) | 2019-03-14 |
US11198713B2 (en) | 2021-12-14 |
US11834482B2 (en) | 2023-12-05 |
EP3678683A4 (fr) | 2021-07-14 |
MX2020002435A (es) | 2020-09-22 |
KR20200064075A (ko) | 2020-06-05 |
JP2020533413A (ja) | 2020-11-19 |
CN111372942A (zh) | 2020-07-03 |
US20200247858A1 (en) | 2020-08-06 |
AU2018329956A1 (en) | 2020-08-20 |
WO2019051327A3 (fr) | 2019-04-18 |
IL273015A (en) | 2020-04-30 |
CA3074838A1 (fr) | 2019-03-14 |
EP3678683A2 (fr) | 2020-07-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA50101A (fr) | Agents de modulation des fonctions de la bêta-caténine et méthodes associées | |
ZA202004932B (en) | Methods and compositions for modulating splicing | |
EP3617784A4 (fr) | Dispositif de modulation de lumière | |
IL285229A (en) | Compounds and methods for modulating RNA function | |
MA48579A (fr) | Anticorps anti-pd1 et méthodes d'utilisation de ceux-ci | |
DK3743406T3 (da) | Tmem16a modulatorer | |
HK1249140A1 (zh) | 用於調節tmprss6表達的化合物和方法 | |
CR20160257A (es) | Anticuerpos e inmunoconjugados anti-cd33 | |
FR3027414B1 (fr) | Modulateur de phase electrooptique et procede de modulation | |
DK3628680T3 (da) | Modulering af komplementaktivitet | |
DK3668512T3 (da) | Pyruvatkinasemodulatorer og anvendelse deraf | |
IL264216A (en) | Compounds and Methods for Modulating SMN2 | |
MA54386A (fr) | Modulateurs de trex1 | |
DK3368046T3 (da) | Synthetic composition and method for modulating brain function and behaviour | |
MA43814A (fr) | Anticorps anti-gitr, méthodes et utilisations | |
FR3027415B1 (fr) | Modulateur de phase electrooptique | |
DK3571193T3 (da) | Potassium Channel Modulators | |
IL256055B (en) | Using h3k9me3 modulation to enhance cognitive function | |
GB2564099B (en) | Electro-Optic Modulator | |
DK3292740T3 (da) | Impulsbreddemodulationslyskildestyring og fremgangsmåde | |
MA53889A (fr) | Prothèse ligamentaire | |
DK3621950T3 (da) | Trpv1-modulatorforbindelser | |
DK3395584T3 (da) | Selvklæbende og genanvendelig notits-bærer | |
GB2575579B (en) | Light modulation element | |
MA43826A (fr) | Inhibiteurs substitués de ménine-mll et méthodes d'utilisation |