MA49569B1 - Procédé de lyophilisation de produit - Google Patents

Procédé de lyophilisation de produit

Info

Publication number
MA49569B1
MA49569B1 MA49569A MA49569A MA49569B1 MA 49569 B1 MA49569 B1 MA 49569B1 MA 49569 A MA49569 A MA 49569A MA 49569 A MA49569 A MA 49569A MA 49569 B1 MA49569 B1 MA 49569B1
Authority
MA
Morocco
Prior art keywords
bag
product
moisture content
drying process
freeze
Prior art date
Application number
MA49569A
Other languages
English (en)
Inventor
Christophe Carite
Sophie Declomesnil
Original Assignee
4D Pharma Leon S L U
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 4D Pharma Leon S L U filed Critical 4D Pharma Leon S L U
Publication of MA49569B1 publication Critical patent/MA49569B1/fr

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D33/00—Details of, or accessories for, sacks or bags
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B25/00—Details of general application not covered by group F26B21/00 or F26B23/00
    • F26B25/001—Handling, e.g. loading or unloading arrangements
    • F26B25/002—Handling, e.g. loading or unloading arrangements for bulk goods
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B25/00—Details of general application not covered by group F26B21/00 or F26B23/00
    • F26B25/06—Chambers, containers, or receptacles
    • F26B25/063—Movable containers or receptacles, e.g. carts, trolleys, pallet-boxes
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B25/00—Details of general application not covered by group F26B21/00 or F26B23/00
    • F26B25/06—Chambers, containers, or receptacles
    • F26B25/14—Chambers, containers, receptacles of simple construction
    • F26B25/16—Chambers, containers, receptacles of simple construction mainly closed, e.g. drum
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/044—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum for drying materials in a batch operation in an enclosure having a plurality of shelves which may be heated
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/08—Drying solid materials or objects by processes not involving the application of heat by centrifugal treatment
    • F26B5/10—Drying solid materials or objects by processes not involving the application of heat by centrifugal treatment the process involving freezing

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Packages (AREA)
  • Drying Of Solid Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La présente invention concerne un procédé de lyophilisation d'un produit (3), consistant à utiliser un système de chargement de produit en vrac (3) sous forme d'un sac (1), le sac (1) comportant un intérieur et un extérieur définis par une paroi souple, le sac (1) comprenant en outre un orifice de remplissage (5) assurant l'accès à l'intérieur du sac (1), à remplir, par l'intermédiaire de l'orifice de remplissage (5), l'intérieur du sac (1) d'un produit (3) présentant une première teneur en humidité, et à exposer le produit (3) à l'intérieur du sac (1) à un cycle de lyophilisation de manière à réduire la teneur en humidité du produit (3), de la première teneur en humidité à une seconde teneur en humidité inférieure.
MA49569A 2017-07-14 2018-07-16 Procédé de lyophilisation de produit MA49569B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1711359.8A GB2564481B (en) 2017-07-14 2017-07-14 Process
PCT/IB2018/055246 WO2019012512A1 (fr) 2017-07-14 2018-07-16 Procédé de lyophilisation de produit

Publications (1)

Publication Number Publication Date
MA49569B1 true MA49569B1 (fr) 2021-07-29

Family

ID=59713621

Family Applications (1)

Application Number Title Priority Date Filing Date
MA49569A MA49569B1 (fr) 2017-07-14 2018-07-16 Procédé de lyophilisation de produit

Country Status (24)

Country Link
US (2) US11135168B2 (fr)
EP (2) EP3652491B1 (fr)
JP (2) JP7049373B2 (fr)
KR (1) KR20200029497A (fr)
CN (2) CN112762661A (fr)
AU (3) AU2018300358B2 (fr)
CA (1) CA3068394A1 (fr)
CY (1) CY1124780T1 (fr)
DK (1) DK3652491T3 (fr)
ES (1) ES2878136T3 (fr)
GB (1) GB2564481B (fr)
HR (1) HRP20211227T1 (fr)
HU (1) HUE055005T2 (fr)
IL (3) IL271979B (fr)
LT (1) LT3652491T (fr)
MA (1) MA49569B1 (fr)
MD (1) MD3652491T2 (fr)
PL (1) PL3652491T3 (fr)
PT (1) PT3652491T (fr)
RS (1) RS62104B1 (fr)
SG (1) SG11202000223UA (fr)
SI (1) SI3652491T1 (fr)
TW (1) TWI771451B (fr)
WO (1) WO2019012512A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
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WO2016022385A1 (fr) * 2014-08-04 2016-02-11 Genentech, Inc. Appareil et procédés pour enfermer hermétiquement un médicament à l'intérieur d'un dispositif d'administration médical
GB2564481B (en) * 2017-07-14 2019-10-23 4D Pharma Leon S L U Process
JP7110360B2 (ja) 2017-10-09 2022-08-01 テルモ ビーシーティー バイオテクノロジーズ，エルエルシー 凍結乾燥方法
CA3130700A1 (fr) 2019-03-14 2020-09-17 Terumo Bct Biotechnologies, Llc Agencement de remplissage de contenant de lyophilisation, systeme et procede d'utilisation
EP3839039A1 (fr) 2019-12-16 2021-06-23 4D Pharma Research Limited Fourniture à la biomasse bactérienne d'une stabilité de stockage améliorée
CN114761537A (zh) 2019-12-20 2022-07-15 4D制药莱昂有限公司 冻干方法
EP4319723A1 (fr) * 2021-04-08 2024-02-14 Evelo Biosciences, Inc. Composition pharmaceutique contenant des bactéries
CN113357880B (zh) * 2021-05-17 2022-11-11 云南易门丛山食用菌有限责任公司 一种半冻干松茸的处理工艺
EP4357709A1 (fr) 2022-10-19 2024-04-24 EAD Sàrl Bouchon de lyophilisation comprenant une membrane
CN117367040A (zh) 2023-11-03 2024-01-09 甘肃省药品检验研究院 一种中药材冷冻干燥的加工装置

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Also Published As

Publication number Publication date
TW201934945A (zh) 2019-09-01
RS62104B1 (sr) 2021-08-31
US20220031621A1 (en) 2022-02-03
ES2878136T3 (es) 2021-11-18
IL289558A (en) 2022-03-01
MD3652491T2 (ro) 2021-09-30
JP7049373B2 (ja) 2022-04-06
EP3652491A1 (fr) 2020-05-20
SI3652491T1 (sl) 2021-09-30
DK3652491T3 (da) 2021-07-05
SG11202000223UA (en) 2020-02-27
US11648204B2 (en) 2023-05-16
IL283604B (en) 2022-02-01
WO2019012512A1 (fr) 2019-01-17
KR20200029497A (ko) 2020-03-18
CN112762661A (zh) 2021-05-07
AU2021201767A1 (en) 2021-04-15
JP2020527688A (ja) 2020-09-10
IL271979B (en) 2021-06-30
PT3652491T (pt) 2021-07-15
JP2022088502A (ja) 2022-06-14
CN110892220A (zh) 2020-03-17
PL3652491T3 (pl) 2021-11-08
EP3652491B1 (fr) 2021-05-12
AU2018300358A1 (en) 2020-01-30
GB2564481B (en) 2019-10-23
CN110892220B (zh) 2021-02-23
US20200179289A1 (en) 2020-06-11
TWI771451B (zh) 2022-07-21
GB2564481A (en) 2019-01-16
US11135168B2 (en) 2021-10-05
GB201711359D0 (en) 2017-08-30
EP3978852A1 (fr) 2022-04-06
IL271979A (en) 2020-02-27
AU2023203930A1 (en) 2023-07-13
HRP20211227T1 (hr) 2021-11-12
CY1124780T1 (el) 2022-11-25
IL283604A (en) 2021-07-29
CA3068394A1 (fr) 2019-01-17
HUE055005T2 (hu) 2021-10-28
LT3652491T (lt) 2021-08-10
AU2018300358B2 (en) 2020-12-24

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