MA47094A - Promédicaments d'ester aliphatique antiviral de ténofovir - Google Patents

Promédicaments d'ester aliphatique antiviral de ténofovir

Info

Publication number
MA47094A
MA47094A MA047094A MA47094A MA47094A MA 47094 A MA47094 A MA 47094A MA 047094 A MA047094 A MA 047094A MA 47094 A MA47094 A MA 47094A MA 47094 A MA47094 A MA 47094A
Authority
MA
Morocco
Prior art keywords
tenofovir
antiviral
aliphatic ester
medicinal products
ester medicinal
Prior art date
Application number
MA047094A
Other languages
English (en)
Inventor
Costa Daniel Da
David Dukhan
Jean-Laurent Paparin
Houcine Rahali
Izzat Raheem
Original Assignee
Idenix Pharmaceuticals Llc
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idenix Pharmaceuticals Llc, Merck Sharp & Dohme filed Critical Idenix Pharmaceuticals Llc
Publication of MA47094A publication Critical patent/MA47094A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/26Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32Nitrogen atom
    • C07D473/34Nitrogen atom attached in position 6, e.g. adenine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA047094A 2016-12-22 2017-12-20 Promédicaments d'ester aliphatique antiviral de ténofovir MA47094A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662437753P 2016-12-22 2016-12-22
US201762574493P 2017-10-19 2017-10-19

Publications (1)

Publication Number Publication Date
MA47094A true MA47094A (fr) 2021-05-26

Family

ID=60972454

Family Applications (1)

Application Number Title Priority Date Filing Date
MA047094A MA47094A (fr) 2016-12-22 2017-12-20 Promédicaments d'ester aliphatique antiviral de ténofovir

Country Status (13)

Country Link
US (1) US10519159B2 (fr)
EP (1) EP3559011B1 (fr)
JP (1) JP6938637B2 (fr)
KR (1) KR20190100250A (fr)
CN (1) CN110099912B (fr)
AU (1) AU2017379850B2 (fr)
BR (1) BR112019013017A2 (fr)
CA (1) CA3047573A1 (fr)
MA (1) MA47094A (fr)
MX (1) MX2019007585A (fr)
RU (1) RU2759902C2 (fr)
TW (1) TW201829412A (fr)
WO (1) WO2018119013A1 (fr)

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EP3532069A4 (fr) 2016-10-26 2020-05-13 Merck Sharp & Dohme Corp. Composés aryl-amide phosphodiamide antiviraux
BR112019012511A2 (pt) 2016-12-22 2019-11-19 Idenix Pharmaceuticals Llc compostos antivirais de benzil-amina fosfodiamida, composição farmacêutica e uso do composto
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WO2017106069A1 (fr) 2015-12-15 2017-06-22 Merck Sharp & Dohme Corp. Composés oximes phosphoramides antiviraux
EP3503895B1 (fr) * 2016-08-25 2021-09-15 Merck Sharp & Dohme Corp. Promédicaments antiviraux du ténofovir
EP3532069A4 (fr) 2016-10-26 2020-05-13 Merck Sharp & Dohme Corp. Composés aryl-amide phosphodiamide antiviraux
BR112019012511A2 (pt) 2016-12-22 2019-11-19 Idenix Pharmaceuticals Llc compostos antivirais de benzil-amina fosfodiamida, composição farmacêutica e uso do composto

Also Published As

Publication number Publication date
CN110099912B (zh) 2021-10-15
CN110099912A (zh) 2019-08-06
JP6938637B2 (ja) 2021-09-22
US20180179208A1 (en) 2018-06-28
EP3559011B1 (fr) 2022-04-13
EP3559011A1 (fr) 2019-10-30
TW201829412A (zh) 2018-08-16
KR20190100250A (ko) 2019-08-28
RU2019122414A3 (fr) 2021-04-26
JP2020504733A (ja) 2020-02-13
AU2017379850A1 (en) 2019-06-13
RU2759902C2 (ru) 2021-11-18
WO2018119013A1 (fr) 2018-06-28
RU2019122414A (ru) 2021-01-25
CA3047573A1 (fr) 2018-06-28
BR112019013017A2 (pt) 2020-01-14
MX2019007585A (es) 2019-09-09
AU2017379850B2 (en) 2022-03-24
US10519159B2 (en) 2019-12-31

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