MA45221A - Nouveaux composés antibactériens - Google Patents

Nouveaux composés antibactériens

Info

Publication number
MA45221A
MA45221A MA045221A MA45221A MA45221A MA 45221 A MA45221 A MA 45221A MA 045221 A MA045221 A MA 045221A MA 45221 A MA45221 A MA 45221A MA 45221 A MA45221 A MA 45221A
Authority
MA
Morocco
Prior art keywords
antibacterial compounds
new antibacterial
new
compounds
antibacterial
Prior art date
Application number
MA045221A
Other languages
English (en)
Inventor
De Joannon Alessandra Capezzone
Guido Furlotti
Barbara Garofalo
Gabriele Magaró
Giorgina Mangano
Rosella Ombrato
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Publication of MA45221A publication Critical patent/MA45221A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/16Peri-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
MA045221A 2016-06-08 2017-06-05 Nouveaux composés antibactériens MA45221A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16173550 2016-06-08

Publications (1)

Publication Number Publication Date
MA45221A true MA45221A (fr) 2021-05-19

Family

ID=56116327

Family Applications (1)

Application Number Title Priority Date Filing Date
MA045221A MA45221A (fr) 2016-06-08 2017-06-05 Nouveaux composés antibactériens

Country Status (27)

Country Link
US (2) US10633366B2 (fr)
EP (2) EP3468970A1 (fr)
JP (2) JP2019517545A (fr)
KR (2) KR20190019084A (fr)
CN (2) CN109790157A (fr)
AR (2) AR108777A1 (fr)
AU (2) AU2017276626A1 (fr)
BR (2) BR112018075297A2 (fr)
CA (2) CA3025624A1 (fr)
CY (1) CY1123194T1 (fr)
DK (1) DK3468975T3 (fr)
EA (2) EA201892815A1 (fr)
ES (1) ES2802233T3 (fr)
HR (1) HRP20200894T1 (fr)
HU (1) HUE049547T2 (fr)
IL (2) IL263285A (fr)
LT (1) LT3468975T (fr)
MA (1) MA45221A (fr)
MD (1) MD3468975T2 (fr)
ME (1) ME03738B (fr)
MX (2) MX2018015126A (fr)
PL (1) PL3468975T3 (fr)
PT (1) PT3468975T (fr)
RS (1) RS60511B1 (fr)
SG (2) SG11201810352XA (fr)
SI (1) SI3468975T1 (fr)
WO (2) WO2017211759A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10633366B2 (en) * 2016-06-08 2020-04-28 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Antibacterial compounds
US11976084B2 (en) 2020-11-23 2024-05-07 Enanta Pharmaceuticals, Inc. Spiropyrrolidine derived antiviral agents
WO2022235605A1 (fr) 2021-05-04 2022-11-10 Enanta Pharmaceuticals, Inc. Nouveaux agents antiviraux macrocycliques
CN113698412A (zh) * 2021-09-01 2021-11-26 临沂大学 一种香豆素并[4,3-b]吡咯类衍生物及其合成方法和应用
WO2023086400A1 (fr) 2021-11-12 2023-05-19 Enanta Pharmaceuticals, Inc. Nouveaux agents antiviraux dérivés de spiropyrrolidine
WO2023086352A1 (fr) 2021-11-12 2023-05-19 Enanta Pharmaceuticals, Inc. Nouveaux agents antiviraux dérivés de spiropyrrolidine
US11858945B2 (en) 2021-11-12 2024-01-02 Enanta Pharmaceuticals, Inc. Alkyne-containing antiviral agents
US11993600B2 (en) 2021-12-08 2024-05-28 Enanta Pharmaceuticals, Inc. Saturated spirocyclics as antiviral agents
WO2023137007A1 (fr) * 2022-01-11 2023-07-20 Enanta Pharmaceuticals, Inc. Procédés de préparation d'acide 4,6,7-trifluoro-1h-indole-2-carboxylique
CN115850672B (zh) * 2022-11-25 2024-07-19 浙江甬仑聚嘉新材料有限公司 一种液晶聚合物及其制备方法和应用

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JP2886570B2 (ja) * 1989-09-29 1999-04-26 エーザイ株式会社 縮合ヘテロ環を有する化合物
IL101722A (en) * 1991-05-02 1996-05-14 Wyeth John & Brother Ltd History of piperazine, their preparation and pharmaceutical preparations containing them
US5607936A (en) 1994-09-30 1997-03-04 Merck & Co., Inc. Substituted aryl piperazines as neurokinin antagonists
FR2822154B1 (fr) 2001-03-13 2005-10-21 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent
JP2005532368A (ja) * 2002-06-12 2005-10-27 アボット・ラボラトリーズ メラニン濃縮ホルモン受容体の拮抗薬
DE102004041163A1 (de) 2004-08-25 2006-03-02 Morphochem Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen mit antibakterieller Aktivität
JP5314244B2 (ja) * 2004-10-27 2013-10-16 富山化学工業株式会社 新規な含窒素複素環化合物およびその塩
AU2006230364B2 (en) 2005-03-31 2012-09-13 Janssen Pharmaceutica N.V. Bicyclic pyrazole compounds as antibacterial agents
US20090131444A1 (en) 2005-05-24 2009-05-21 Astrazeneca Ab Aminopiperidine Quinolines and Their Azaisosteric Analogues with Antibacterial Activity
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
EP2468743A1 (fr) * 2005-06-24 2012-06-27 Toyama Chemical Co., Ltd. Composés hétérocycliques bicycliques contenant de l'azote utiles en tant qu'agents antibactériens
CN101346379A (zh) * 2005-10-21 2009-01-14 葛兰素集团有限公司 用作抗菌剂的周环并合的三环化合物
EP2481735A1 (fr) * 2007-05-09 2012-08-01 Pfizer Inc. Dérivés hétérocycliques substitués et leur utilisation pharmaceutique et compositions
JP5620636B2 (ja) * 2007-11-26 2014-11-05 富山化学工業株式会社 新規な複素環化合物またはその塩を含有する抗菌剤
JP2011520944A (ja) * 2008-05-23 2011-07-21 グラクソ グループ リミテッド 窒素含有三環式化合物および抗菌剤としてのその使用
JP5474941B2 (ja) 2008-05-23 2014-04-16 グラクソ グループ リミテッド 窒素含有三環式化合物およびその抗菌剤としての使用
TW201022279A (en) * 2008-11-14 2010-06-16 Astrazeneca Ab Chemical compounds
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AU2010206161B2 (en) 2009-01-21 2014-08-07 Basilea Pharmaceutica Ag Novel bicyclic antibiotics
WO2012003418A2 (fr) 2010-07-02 2012-01-05 The University Of North Carolina At Chapel Hill Ligands fonctionnellement sélectifs des récepteurs d2 de dopamine
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AU2012275499A1 (en) * 2011-06-27 2013-12-19 Kyorin Pharmaceutical Co., Ltd. Bridged bicyclic compounds for the treatment of bacterial infections
EP2776431B1 (fr) 2011-11-08 2016-05-04 Actelion Pharmaceuticals Ltd. Dérivés de la 2-oxo-oxazolidin-3,5-diyle antibiotiques
JP2014533747A (ja) 2011-11-30 2014-12-15 アクテリオン ファーマシューティカルズ リミテッドActelion Pharmaceuticals Ltd 3,7−二置換オクタヒドロ−2H−ピリド[4,3−e][1,3]オキサジン−2−オン抗生物質
CN105218501A (zh) * 2014-07-03 2016-01-06 南京大学 含哌嗪环的香豆素类衍生物及其制备与在抗菌药物中的应用
MX2017002321A (es) 2014-08-22 2017-08-02 Glaxosmithkline Ip Dev Ltd Compuestos que contienen nitrogeno triciclico para tratar infeccion por neisseria gonorrhoeae.
MA41169A (fr) * 2014-12-17 2017-10-24 Acraf Composés antibactériens à large spectre d'activité
MA41168A (fr) * 2014-12-17 2017-10-24 Acraf Nouveaux composés antibactériens
US10633366B2 (en) * 2016-06-08 2020-04-28 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Antibacterial compounds

Also Published As

Publication number Publication date
US10633366B2 (en) 2020-04-28
MD3468975T2 (ro) 2020-08-31
EA201892815A1 (ru) 2019-05-31
US20190256495A1 (en) 2019-08-22
SI3468975T1 (sl) 2020-08-31
MX2018015126A (es) 2019-09-02
PL3468975T3 (pl) 2020-09-07
US20190161472A1 (en) 2019-05-30
IL263285A (en) 2018-12-31
DK3468975T3 (da) 2020-07-13
EP3468975B1 (fr) 2020-04-01
EP3468975A1 (fr) 2019-04-17
SG11201810352XA (en) 2018-12-28
MX2018015125A (es) 2019-09-02
JP2019517545A (ja) 2019-06-24
US20200095225A9 (en) 2020-03-26
KR20190019083A (ko) 2019-02-26
CN109790157A (zh) 2019-05-21
SG11201810389XA (en) 2018-12-28
AR108777A1 (es) 2018-09-26
AU2017276626A1 (en) 2018-12-20
ES2802233T3 (es) 2021-01-18
IL263283A (en) 2018-12-31
CY1123194T1 (el) 2021-10-29
HRP20200894T1 (hr) 2020-09-18
BR112018075297A2 (pt) 2019-03-19
HUE049547T2 (hu) 2020-10-28
WO2017211759A1 (fr) 2017-12-14
PT3468975T (pt) 2020-06-23
EP3468970A1 (fr) 2019-04-17
CA3025624A1 (fr) 2017-12-14
LT3468975T (lt) 2020-08-10
RS60511B1 (sr) 2020-08-31
CA3025270A1 (fr) 2017-12-14
ME03738B (fr) 2021-01-20
CN109415373A (zh) 2019-03-01
WO2017211760A1 (fr) 2017-12-14
AU2017276627A1 (en) 2018-12-20
US10640488B2 (en) 2020-05-05
EA201892822A1 (ru) 2019-06-28
JP2019517546A (ja) 2019-06-24
BR112018075334A2 (pt) 2019-03-19
AR108778A1 (es) 2018-09-26
KR20190019084A (ko) 2019-02-26

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