MA43183A - Agent thérapeutique antitumoral contenant une composition liposomale à base de gemcitabine et kit associé - Google Patents

Agent thérapeutique antitumoral contenant une composition liposomale à base de gemcitabine et kit associé

Info

Publication number
MA43183A
MA43183A MA043183A MA43183A MA43183A MA 43183 A MA43183 A MA 43183A MA 043183 A MA043183 A MA 043183A MA 43183 A MA43183 A MA 43183A MA 43183 A MA43183 A MA 43183A
Authority
MA
Morocco
Prior art keywords
gemcitabine
therapeutic agent
agent containing
composition based
liposomal composition
Prior art date
Application number
MA043183A
Other languages
English (en)
Inventor
Tsukasa KITAHASHI
Takeshi Matsumoto
Shinji Mima
Mikinaga Mori
Takahiro Sekiguchi
Original Assignee
Fujifilm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Corp filed Critical Fujifilm Corp
Publication of MA43183A publication Critical patent/MA43183A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/643Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
MA043183A 2015-11-02 2016-11-01 Agent thérapeutique antitumoral contenant une composition liposomale à base de gemcitabine et kit associé MA43183A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2015215768 2015-11-02

Publications (1)

Publication Number Publication Date
MA43183A true MA43183A (fr) 2018-09-12

Family

ID=58662534

Family Applications (1)

Application Number Title Priority Date Filing Date
MA043183A MA43183A (fr) 2015-11-02 2016-11-01 Agent thérapeutique antitumoral contenant une composition liposomale à base de gemcitabine et kit associé

Country Status (11)

Country Link
US (3) US11166913B2 (fr)
EP (1) EP3372232B1 (fr)
JP (1) JP6602886B2 (fr)
KR (1) KR102084340B1 (fr)
CN (3) CN108348538B (fr)
DK (1) DK3372232T3 (fr)
ES (1) ES2869283T3 (fr)
MA (1) MA43183A (fr)
PL (1) PL3372232T3 (fr)
RU (3) RU2768178C2 (fr)
WO (1) WO2017078008A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3138555B1 (fr) 2014-04-30 2020-10-28 FUJIFILM Corporation Composition liposomale et procédé de production associé
CN108348538B (zh) 2015-11-02 2021-06-22 富士胶片株式会社 包含吉西他滨脂质体组合物的肿瘤治疗药及试剂盒
EP3603620A4 (fr) 2017-03-31 2020-03-25 FUJIFILM Corporation Composition de liposome et composition pharmaceutique
EP3811931A4 (fr) * 2018-06-20 2021-08-04 FUJIFILM Corporation Médicament combiné contenant une composition de liposome encapsulant un médicament et un inhibiteur de point de contrôle immunitaire
CA3104084C (fr) * 2018-06-20 2023-08-01 Fujifilm Corporation Medicament combine comprenant une composition de liposome encapsulee par gemcitabine et un blocage de point de controle immunitaire
JP7057434B2 (ja) * 2018-10-01 2022-04-19 富士フイルム株式会社 薬物を内包するリポソーム組成物およびプラチナ製剤を含む組合せ医薬
CN112898277B (zh) * 2019-11-19 2022-04-22 扬子江药业集团有限公司 一种阿法替尼中间体的制备方法
CN111035616B (zh) * 2019-12-30 2022-03-22 上海景峰制药有限公司 一种吉西他滨脂质体及其制备方法和应用
JP2021181426A (ja) * 2020-04-03 2021-11-25 富士フイルム株式会社 抗腫瘍剤
WO2023179423A1 (fr) * 2022-03-25 2023-09-28 四川科伦药物研究院有限公司 Composition pharmaceutique de liposome de gemcitabine, son procédé de préparation et son utilisation
WO2023186923A1 (fr) 2022-03-30 2023-10-05 Meta Materials Inc. Système implanté d'administration d'agent

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5049392A (en) * 1989-01-18 1991-09-17 The Liposome Company, Inc. Osmotically dependent vesicles
AU2003268087A1 (en) 2002-08-23 2004-03-11 Ian Ma Liposomal gemcitabine compositions for better drug delivery
EP1643971A2 (fr) * 2003-05-22 2006-04-12 Neopharm, Inc. Formulations liposomales combinees
JPWO2005021012A1 (ja) * 2003-08-29 2006-10-26 テルモ株式会社 ゲムシタビン封入薬剤担体
KR101462825B1 (ko) 2004-05-03 2014-11-21 헤르메스 바이오사이언스, 인코포레이티드 약물 전달에 유용한 리포좀
US20070014845A1 (en) * 2005-07-01 2007-01-18 Yuanpeng Zhang Liposomal delivery vehicle for hydrophobic drugs
WO2007067784A2 (fr) * 2005-12-08 2007-06-14 Wyeth Compositions liposomales
US8119156B2 (en) * 2006-10-24 2012-02-21 Aradigm Corporation Dual action, inhaled formulations providing both an immediate and sustained release profile
CN101209243B (zh) 2006-12-29 2010-12-08 石药集团中奇制药技术(石家庄)有限公司 一种脂质体药物及其制备方法
CN100496609C (zh) * 2006-12-30 2009-06-10 上海艾力斯医药科技有限公司 一种稳定的脂质体组合物
EP2171135A2 (fr) * 2007-06-22 2010-04-07 Innovative Surface Technologies, Inc. Nanofibres sensibles à des stimuli
US20100239652A1 (en) * 2007-09-28 2010-09-23 Universitatsspital Basel Immunoliposomes for treatment of cancer
US8079820B2 (en) * 2008-12-18 2011-12-20 General Electric Company Blade module, a modular rotor blade and a method for assembling a modular rotor blade
EP2394640A1 (fr) 2010-05-21 2011-12-14 MediGene AG Formulations liposomales améliorées de composés lipophiles
RU2571077C2 (ru) * 2011-03-25 2015-12-20 Терумо Кабусики Кайся Липосомальная композиция длительного действия с контролируемым высвобождением и способ ее получения
US8987224B2 (en) * 2011-08-05 2015-03-24 Baylor College Of Medicine MicroRNA-198 as a tumor suppressor in pancreatic cancer
MX360391B (es) * 2011-10-31 2018-10-31 Mallinckrodt Llc Composiciones liposomales combinadas para terapia contra el cancer.
EP2604253A1 (fr) * 2011-12-13 2013-06-19 Otto Glatter Émulsion eau dans l'huile et leurs procédés de préparation
ES2673093T3 (es) * 2012-04-04 2018-06-19 Halozyme, Inc. Terapia combinada con hialuronidasa y un taxano dirigido a un tumor
CN102784107B (zh) * 2012-05-17 2015-04-22 江苏豪森药业股份有限公司 一种吉西他滨或其盐脂质体及其制备方法和用途
AU2013360302C1 (en) * 2012-12-12 2019-01-24 Temple University - Of The Commonwealth System Of Higher Education Compositions and methods for treatment of cancer
CA2936345A1 (fr) 2013-01-14 2014-07-17 Chemo-Enhanced Llc Compositions et procedes pour traiter le cancer
WO2014138278A1 (fr) 2013-03-05 2014-09-12 The Regents Of The University Of California Nanoparticules de silice mésoporeuse revêtues par une bi-couche lipidique ayant une capacité élevée de charge pour un ou plusieurs agents anticancer
WO2015166987A1 (fr) * 2014-04-30 2015-11-05 富士フイルム株式会社 Composition liposomale et procédé de production associé
WO2015166985A1 (fr) * 2014-04-30 2015-11-05 富士フイルム株式会社 Composition liposomale et procédé de production associé
CN108348538B (zh) 2015-11-02 2021-06-22 富士胶片株式会社 包含吉西他滨脂质体组合物的肿瘤治疗药及试剂盒
WO2017192863A1 (fr) * 2016-05-04 2017-11-09 L.E.A.F. Holdings Group Llc Compositions de gemcitabine liposomale ciblée et procédés correspondants

Also Published As

Publication number Publication date
CN111632030A (zh) 2020-09-08
US11166913B2 (en) 2021-11-09
RU2761620C2 (ru) 2021-12-13
RU2018119680A (ru) 2019-12-05
RU2020137385A (ru) 2020-12-03
CN111437259A (zh) 2020-07-24
KR20180054873A (ko) 2018-05-24
ES2869283T3 (es) 2021-10-25
DK3372232T3 (da) 2021-06-07
RU2020137385A3 (fr) 2021-03-31
US20210275453A1 (en) 2021-09-09
WO2017078008A1 (fr) 2017-05-11
JPWO2017078008A1 (ja) 2018-08-09
EP3372232A4 (fr) 2018-11-14
US11166914B2 (en) 2021-11-09
CN108348538B (zh) 2021-06-22
CN108348538A (zh) 2018-07-31
EP3372232B1 (fr) 2021-04-14
RU2020137384A3 (fr) 2021-03-31
JP6602886B2 (ja) 2019-11-06
PL3372232T3 (pl) 2021-09-27
EP3372232A1 (fr) 2018-09-12
US20200197305A1 (en) 2020-06-25
RU2020137384A (ru) 2020-12-03
RU2018119680A3 (fr) 2019-12-05
RU2768178C2 (ru) 2022-03-23
CN111632030B (zh) 2023-01-17
KR102084340B1 (ko) 2020-03-03
US20180243214A1 (en) 2018-08-30
RU2738365C2 (ru) 2020-12-11

Similar Documents

Publication Publication Date Title
MA43183A (fr) Agent thérapeutique antitumoral contenant une composition liposomale à base de gemcitabine et kit associé
DK3706796T3 (da) Eksosomerer som RNA terapeutikske midler
MA43377A (fr) Méthodes et compositions liées à la toxicité associée à la thérapie cellulaire
DK3357513T3 (da) Farmaceutisk sammensætning og anvendelse deraf
GB201715898D0 (en) Proactive virtual assistant
MA40764A (fr) Agent thérapeutique induisant une cytotoxicité
GEP20217239B (en) Pharmaceutical composition
ES2841649T5 (es) Composición farmacéutica
DK3412660T3 (da) Sulfonamidderivat og farmaceutisk sammensætning indeholdende samme
PT3513809T (pt) Composição medicinal compreendendo tivozanib
DK3386523T3 (da) Bifidobacterium longum til behandling af fedme og associerede metabolske sygdomme
MA51228A (fr) Agent antitumoral
DK3408265T3 (da) Terapeutiske forbindelser
FR23C1037I1 (fr) Compositions à base de mycoplasma bovis
DK3275457T3 (da) Farmaceutisk sammensætning omfattende silybin og pu'er-te-essens
BR112016030507A2 (pt) Compostos relacionados à vitamina d, composição farmacêutica, e kit
DK3154542T3 (da) Fremgangsmåder og sammensætninger rettet mod depressionsfølelse
DK3512544T3 (da) Peptidforbindelser og terapeutiske anvendelser deraf
DK3432887T3 (da) Anti-tuberkulosemiddel
DK3302483T3 (da) Farmaceutiske sammensætninger og anvendelse deraf
ITUB20156000A1 (it) Composizione nematocida e suo utilizzo
DK3359185T3 (da) Antitumoral sammensætning
DK3373976T3 (da) Topiske formuleringer og anvendelser deraf
LU92630B1 (fr) Compositions contenant de la curcumine à biodisponibilité améliorée
IL260569B (en) Radiolabeled erlotinib analogs and uses thereof