MA43183A - Agent thérapeutique antitumoral contenant une composition liposomale à base de gemcitabine et kit associé - Google Patents

Agent thérapeutique antitumoral contenant une composition liposomale à base de gemcitabine et kit associé

Info

Publication number
MA43183A
MA43183A MA043183A MA43183A MA43183A MA 43183 A MA43183 A MA 43183A MA 043183 A MA043183 A MA 043183A MA 43183 A MA43183 A MA 43183A MA 43183 A MA43183 A MA 43183A
Authority
MA
Morocco
Prior art keywords
gemcitabine
therapeutic agent
agent containing
composition based
liposomal composition
Prior art date
Application number
MA043183A
Other languages
English (en)
Inventor
Tsukasa KITAHASHI
Takeshi Matsumoto
Shinji Mima
Mikinaga Mori
Takahiro Sekiguchi
Original Assignee
Fujifilm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Corp filed Critical Fujifilm Corp
Publication of MA43183A publication Critical patent/MA43183A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/643Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
MA043183A 2015-11-02 2016-11-01 Agent thérapeutique antitumoral contenant une composition liposomale à base de gemcitabine et kit associé MA43183A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2015215768 2015-11-02

Publications (1)

Publication Number Publication Date
MA43183A true MA43183A (fr) 2018-09-12

Family

ID=58662534

Family Applications (1)

Application Number Title Priority Date Filing Date
MA043183A MA43183A (fr) 2015-11-02 2016-11-01 Agent thérapeutique antitumoral contenant une composition liposomale à base de gemcitabine et kit associé

Country Status (11)

Country Link
US (3) US11166913B2 (fr)
EP (1) EP3372232B1 (fr)
JP (1) JP6602886B2 (fr)
KR (1) KR102084340B1 (fr)
CN (3) CN111632030B (fr)
DK (1) DK3372232T3 (fr)
ES (1) ES2869283T3 (fr)
MA (1) MA43183A (fr)
PL (1) PL3372232T3 (fr)
RU (3) RU2738365C2 (fr)
WO (1) WO2017078008A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2836772T3 (es) 2014-04-30 2021-06-28 Fujifilm Corp Composición liposomal y método para producirla
KR102084340B1 (ko) 2015-11-02 2020-03-03 후지필름 가부시키가이샤 젬시타빈 리포솜 조성물을 포함하는 종양 치료제 및 키트
AU2018246024B2 (en) 2017-03-31 2020-08-06 Fujifilm Corporation Liposome composition and pharmaceutical composition
FI3811949T3 (fi) * 2018-06-20 2024-09-13 Fujifilm Corp Liposomikoostumukseen kapseloitua gemsitabiinia ja immuunitarkistuspistesalpaajaa käsittävä yhdistelmälääke
CN112312895B (zh) * 2018-06-20 2023-05-09 富士胶片株式会社 包含内含药物的脂质体组合物及免疫检查点抑制剂的组合医药
TWI837189B (zh) * 2018-10-01 2024-04-01 日商富士軟片股份有限公司 包含內含藥物之脂質體組成物及鉑製劑之組合醫藥
CN112898277B (zh) * 2019-11-19 2022-04-22 扬子江药业集团有限公司 一种阿法替尼中间体的制备方法
CN111035616B (zh) * 2019-12-30 2022-03-22 上海景峰制药有限公司 一种吉西他滨脂质体及其制备方法和应用
JP2021181426A (ja) * 2020-04-03 2021-11-25 富士フイルム株式会社 抗腫瘍剤
WO2023179423A1 (fr) 2022-03-25 2023-09-28 四川科伦药物研究院有限公司 Composition pharmaceutique de liposome de gemcitabine, son procédé de préparation et son utilisation
WO2023186923A1 (fr) 2022-03-30 2023-10-05 Meta Materials Inc. Système implanté d'administration d'agent

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5049392A (en) * 1989-01-18 1991-09-17 The Liposome Company, Inc. Osmotically dependent vesicles
WO2004017944A1 (fr) 2002-08-23 2004-03-04 Neopharm, Inc. Compositions de gemcitabine pour une administration de medicaments amelioree
EP1643971A2 (fr) 2003-05-22 2006-04-12 Neopharm, Inc. Formulations liposomales combinees
WO2005021012A1 (fr) * 2003-08-29 2005-03-10 Terumo Kabushiki Kaisha Vecteur de medicament contenant de la gemcitabine
KR101462819B1 (ko) 2004-05-03 2014-11-21 헤르메스 바이오사이언스, 인코포레이티드 약물 전달에 유용한 리포좀
US20070014845A1 (en) * 2005-07-01 2007-01-18 Yuanpeng Zhang Liposomal delivery vehicle for hydrophobic drugs
JP2009519250A (ja) * 2005-12-08 2009-05-14 ワイス リポソーム組成物
US8119156B2 (en) * 2006-10-24 2012-02-21 Aradigm Corporation Dual action, inhaled formulations providing both an immediate and sustained release profile
CN101209243B (zh) 2006-12-29 2010-12-08 石药集团中奇制药技术(石家庄)有限公司 一种脂质体药物及其制备方法
CN100496609C (zh) * 2006-12-30 2009-06-10 上海艾力斯医药科技有限公司 一种稳定的脂质体组合物
WO2009002858A2 (fr) * 2007-06-22 2008-12-31 Innovative Surface Technologies, Inc. Nanofibres sensibles à des stimuli
CA2700810A1 (fr) * 2007-09-28 2009-04-02 Universitatsspital Basel Immunoliposomes utilises pour le traitement du cancer
US8079820B2 (en) * 2008-12-18 2011-12-20 General Electric Company Blade module, a modular rotor blade and a method for assembling a modular rotor blade
EP2394640A1 (fr) * 2010-05-21 2011-12-14 MediGene AG Formulations liposomales améliorées de composés lipophiles
WO2012133121A1 (fr) * 2011-03-25 2012-10-04 テルモ株式会社 Composition liposomale de longue durée à libération prolongée et son procédé de fabrication
US8987224B2 (en) * 2011-08-05 2015-03-24 Baylor College Of Medicine MicroRNA-198 as a tumor suppressor in pancreatic cancer
EP2773426B1 (fr) * 2011-10-31 2018-08-22 Mallinckrodt LLC Compositions liposomales combinatoires pour le traitement du cancer
EP2604253A1 (fr) * 2011-12-13 2013-06-19 Otto Glatter Émulsion eau dans l'huile et leurs procédés de préparation
EP2833905B1 (fr) 2012-04-04 2018-05-02 Halozyme, Inc. Combinaison de la hyaluronidase et d'un taxane ciblé de tumeur
CN102784107B (zh) * 2012-05-17 2015-04-22 江苏豪森药业股份有限公司 一种吉西他滨或其盐脂质体及其制备方法和用途
CA2894846A1 (fr) * 2012-12-12 2014-06-19 Temple University - Of The Commonwealth System Of Higher Education Compositions et methodes de traitement du cancer
US9968570B2 (en) 2013-01-14 2018-05-15 Chemo-Enhanced Llc Compositions and methods for treating cancer
EP2964201B1 (fr) 2013-03-05 2024-02-14 The Regents of the University of California Nanoparticules de silice mésoporeuse revêtues par une bi-couche lipidique ayant une capacité élevée de charge pour un ou plusieurs agents anticancer
JP6263609B2 (ja) * 2014-04-30 2018-01-17 富士フイルム株式会社 リポソーム組成物及びその製造方法
WO2015166987A1 (fr) * 2014-04-30 2015-11-05 富士フイルム株式会社 Composition liposomale et procédé de production associé
KR102084340B1 (ko) 2015-11-02 2020-03-03 후지필름 가부시키가이샤 젬시타빈 리포솜 조성물을 포함하는 종양 치료제 및 키트
WO2017192863A1 (fr) * 2016-05-04 2017-11-09 L.E.A.F. Holdings Group Llc Compositions de gemcitabine liposomale ciblée et procédés correspondants

Also Published As

Publication number Publication date
EP3372232B1 (fr) 2021-04-14
RU2018119680A (ru) 2019-12-05
KR20180054873A (ko) 2018-05-24
US11166914B2 (en) 2021-11-09
US20180243214A1 (en) 2018-08-30
JP6602886B2 (ja) 2019-11-06
RU2018119680A3 (fr) 2019-12-05
US11166913B2 (en) 2021-11-09
CN108348538B (zh) 2021-06-22
EP3372232A1 (fr) 2018-09-12
CN111632030A (zh) 2020-09-08
JPWO2017078008A1 (ja) 2018-08-09
CN111437259A (zh) 2020-07-24
WO2017078008A1 (fr) 2017-05-11
RU2768178C2 (ru) 2022-03-23
RU2761620C2 (ru) 2021-12-13
PL3372232T3 (pl) 2021-09-27
CN108348538A (zh) 2018-07-31
KR102084340B1 (ko) 2020-03-03
DK3372232T3 (da) 2021-06-07
ES2869283T3 (es) 2021-10-25
US20210275453A1 (en) 2021-09-09
CN111632030B (zh) 2023-01-17
RU2020137384A3 (fr) 2021-03-31
RU2020137385A (ru) 2020-12-03
US20200197305A1 (en) 2020-06-25
RU2738365C2 (ru) 2020-12-11
RU2020137385A3 (fr) 2021-03-31
RU2020137384A (ru) 2020-12-03
EP3372232A4 (fr) 2018-11-14

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