MA32969B1 - Compositions pharmaceutiques presentant de remarquables performances et entrainant une excellente adhesion du patient a son traitement - Google Patents

Compositions pharmaceutiques presentant de remarquables performances et entrainant une excellente adhesion du patient a son traitement

Info

Publication number
MA32969B1
MA32969B1 MA34019A MA34019A MA32969B1 MA 32969 B1 MA32969 B1 MA 32969B1 MA 34019 A MA34019 A MA 34019A MA 34019 A MA34019 A MA 34019A MA 32969 B1 MA32969 B1 MA 32969B1
Authority
MA
Morocco
Prior art keywords
treatment
pharmaceutical compositions
remarkable performance
excellent patient
patient membership
Prior art date
Application number
MA34019A
Other languages
Arabic (ar)
English (en)
Inventor
Ashish Chatterji
Dipen Desai
Harpreet K Sandhu
Navnit Hargovindas Shah
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MA32969B1 publication Critical patent/MA32969B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne de nouvelles formulations de l'ester (2R,3R,4R,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-4-fluoro-2-isobutyryloxyméthyl-4-méthyl-tétrahydro-furan-3-ylique de l'acide isobutyrique et de l'hydroxypropylcellulose, caractérisées par une masse volumique apparente élevée, par une faible taille des particules permettant une meilleure compression et une fluidité améliorée, par une bonne compression et par des profils de dissolution rapides.
MA34019A 2009-01-21 2010-01-11 Compositions pharmaceutiques presentant de remarquables performances et entrainant une excellente adhesion du patient a son traitement MA32969B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14599909P 2009-01-21 2009-01-21
PCT/EP2010/050182 WO2010084041A2 (fr) 2009-01-21 2010-01-11 Compositions pharmaceutiques présentant de remarquables performances et entraînant une excellente adhésion du patient à son traitement

Publications (1)

Publication Number Publication Date
MA32969B1 true MA32969B1 (fr) 2012-01-02

Family

ID=42026386

Family Applications (1)

Application Number Title Priority Date Filing Date
MA34019A MA32969B1 (fr) 2009-01-21 2010-01-11 Compositions pharmaceutiques presentant de remarquables performances et entrainant une excellente adhesion du patient a son traitement

Country Status (28)

Country Link
US (1) US8222230B2 (fr)
EP (1) EP2389164B1 (fr)
JP (1) JP5415561B2 (fr)
KR (1) KR101331723B1 (fr)
CN (1) CN102292075B (fr)
AR (1) AR075037A1 (fr)
AU (1) AU2010206224B2 (fr)
BR (1) BRPI1006924A2 (fr)
CA (1) CA2748895C (fr)
CL (1) CL2011001764A1 (fr)
CO (1) CO6440558A2 (fr)
DK (1) DK2389164T3 (fr)
EC (1) ECSP11011191A (fr)
ES (1) ES2513415T3 (fr)
HK (1) HK1164742A1 (fr)
IL (1) IL213804A0 (fr)
MA (1) MA32969B1 (fr)
MX (1) MX2011007771A (fr)
NZ (1) NZ593795A (fr)
PE (1) PE20120020A1 (fr)
PL (1) PL2389164T3 (fr)
RU (1) RU2489153C2 (fr)
SG (1) SG173001A1 (fr)
SI (1) SI2389164T1 (fr)
TW (1) TWI414295B (fr)
UA (1) UA100937C2 (fr)
WO (1) WO2010084041A2 (fr)
ZA (1) ZA201104882B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012062691A1 (fr) * 2010-11-09 2012-05-18 F. Hoffmann-La Roche Ag Compositions pharmaceutiques pour le traitement des infections par le virus de l'hépatite c
CN105050708A (zh) 2012-11-14 2015-11-11 格雷斯公司 含有生物活性材料与无序无机氧化物的组合物
DE102013215831A1 (de) * 2013-08-09 2015-02-12 Beiersdorf Ag Gelförmiges, alkoholisches Sonnenschutzmittel
WO2016121925A1 (fr) * 2015-01-30 2016-08-04 協和発酵バイオ株式会社 Comprimé contenant une proportion élevée de substance fonctionnelle et procédé de fabrication dudit comprimé
WO2017140253A1 (fr) * 2016-02-19 2017-08-24 江苏恒瑞医药股份有限公司 Composition pharmaceutique contenant un dérivé d'imidazoline
JP6323846B2 (ja) * 2016-04-07 2018-05-16 塩野義製薬株式会社 オピオイドを含有する乱用防止製剤

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0400726A3 (en) * 2001-01-22 2007-05-29 Merck & Co Inc Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase
JP4408340B2 (ja) * 2002-03-22 2010-02-03 武田薬品工業株式会社 速崩壊性固形製剤
TWI332507B (en) * 2002-11-19 2010-11-01 Hoffmann La Roche Antiviral nucleoside derivatives
KR20080027783A (ko) * 2005-06-22 2008-03-28 다케다 야쿠힌 고교 가부시키가이샤 난용성 활성 성분을 함유하는 정제
JP2008230967A (ja) * 2005-06-23 2008-10-02 Kowa Co 医薬組成物
NZ568909A (en) * 2005-12-09 2011-10-28 Hoffmann La Roche Antiviral 4-fluoro-4-methyl nucleoside prodrugs
BRPI0619890A2 (pt) * 2005-12-14 2011-10-25 Hoffmann La Roche composição farmacêutica e processo para preparação de uma suspensão sólida

Also Published As

Publication number Publication date
SI2389164T1 (sl) 2014-12-31
AU2010206224B2 (en) 2012-12-13
ECSP11011191A (es) 2011-10-31
EP2389164B1 (fr) 2014-08-13
WO2010084041A2 (fr) 2010-07-29
US20100184716A1 (en) 2010-07-22
US8222230B2 (en) 2012-07-17
CO6440558A2 (es) 2012-05-15
DK2389164T3 (da) 2014-09-15
MX2011007771A (es) 2011-08-12
KR20110117683A (ko) 2011-10-27
PE20120020A1 (es) 2012-02-02
RU2489153C2 (ru) 2013-08-10
TWI414295B (zh) 2013-11-11
SG173001A1 (en) 2011-08-29
ZA201104882B (en) 2012-03-28
CA2748895A1 (fr) 2010-07-29
CN102292075A (zh) 2011-12-21
AR075037A1 (es) 2011-03-02
IL213804A0 (en) 2011-07-31
EP2389164A2 (fr) 2011-11-30
TW201031410A (en) 2010-09-01
CN102292075B (zh) 2013-04-17
NZ593795A (en) 2013-02-22
AU2010206224A1 (en) 2011-08-25
CA2748895C (fr) 2014-05-13
HK1164742A1 (en) 2012-09-28
BRPI1006924A2 (pt) 2016-02-16
ES2513415T3 (es) 2014-10-27
JP2012515739A (ja) 2012-07-12
KR101331723B1 (ko) 2013-11-26
JP5415561B2 (ja) 2014-02-12
RU2011134713A (ru) 2013-03-10
PL2389164T3 (pl) 2015-01-30
WO2010084041A3 (fr) 2011-08-18
UA100937C2 (uk) 2013-02-11
CL2011001764A1 (es) 2012-01-20

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