MA31985B1 - (r)-2-(4-cyclopropanesulfonyl-phényl)-n-pyrazin-2-yl-3-(tétrahydropyran-4-yl)- propionamide cristallin - Google Patents
(r)-2-(4-cyclopropanesulfonyl-phényl)-n-pyrazin-2-yl-3-(tétrahydropyran-4-yl)- propionamide cristallinInfo
- Publication number
- MA31985B1 MA31985B1 MA32927A MA32927A MA31985B1 MA 31985 B1 MA31985 B1 MA 31985B1 MA 32927 A MA32927 A MA 32927A MA 32927 A MA32927 A MA 32927A MA 31985 B1 MA31985 B1 MA 31985B1
- Authority
- MA
- Morocco
- Prior art keywords
- pyrazin
- propionamide
- tetrahydropyran
- crystalline
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
2-(4-cyclopropanesulphonyl-phényl)-n-pyrazin-2-yl-3-(tétrahydropyran-4-yl)-propionamide cristallin.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2113308P | 2008-01-15 | 2008-01-15 | |
PCT/US2009/030241 WO2009091634A1 (fr) | 2008-01-15 | 2009-01-07 | 2-(4-cyclopropanesulphonyl-phényl)-n-pyrazin-2-yl-3-(tétrahydropyran-4-yl)-propionamide cristallin |
Publications (1)
Publication Number | Publication Date |
---|---|
MA31985B1 true MA31985B1 (fr) | 2011-01-03 |
Family
ID=40451065
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA32927A MA31985B1 (fr) | 2008-01-15 | 2010-06-16 | (r)-2-(4-cyclopropanesulfonyl-phényl)-n-pyrazin-2-yl-3-(tétrahydropyran-4-yl)- propionamide cristallin |
Country Status (22)
Country | Link |
---|---|
US (1) | US20090181981A1 (fr) |
EP (1) | EP2265271A1 (fr) |
JP (1) | JP2011509934A (fr) |
KR (1) | KR20100092061A (fr) |
CN (1) | CN101909629A (fr) |
AR (1) | AR070107A1 (fr) |
AU (1) | AU2009205606A1 (fr) |
BR (1) | BRPI0907165A2 (fr) |
CA (1) | CA2712245A1 (fr) |
CL (1) | CL2009000004A1 (fr) |
CO (1) | CO6280489A2 (fr) |
DO (1) | DOP2010000216A (fr) |
EA (1) | EA201070853A1 (fr) |
EC (1) | ECSP10010347A (fr) |
IL (1) | IL206102A0 (fr) |
MA (1) | MA31985B1 (fr) |
MX (1) | MX2010007784A (fr) |
PE (1) | PE20091313A1 (fr) |
TN (1) | TN2010000299A1 (fr) |
TW (1) | TW200934772A (fr) |
WO (1) | WO2009091634A1 (fr) |
ZA (1) | ZA201003909B (fr) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT2195293E (pt) | 2007-08-22 | 2014-01-21 | Astrazeneca Ab | Derivados da ciclopropilamida |
TW201039825A (en) | 2009-02-20 | 2010-11-16 | Astrazeneca Ab | Cyclopropyl amide derivatives 983 |
AU2011218490B9 (en) * | 2010-02-18 | 2014-12-18 | Astrazeneca Ab | Solid forms comprising a cyclopropyl amide derivative |
RU2012136148A (ru) | 2010-02-18 | 2014-03-27 | Астразенека Аб | Новая кристаллическая форма производного циклопропилбензамида |
WO2011107494A1 (fr) | 2010-03-03 | 2011-09-09 | Sanofi | Nouveaux dérivés aromatiques de glycoside, médicaments contenants ces composés, et leur utilisation |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
KR101220371B1 (ko) | 2010-09-17 | 2013-01-09 | 현대자동차주식회사 | 베인펌프 |
JP5966186B2 (ja) * | 2011-02-08 | 2016-08-10 | 国立大学法人高知大学 | カルサイト単結晶の製造方法 |
JP2013014534A (ja) * | 2011-07-04 | 2013-01-24 | Daicel Corp | ベンゾイルギ酸化合物、及びその製造方法 |
WO2013037390A1 (fr) | 2011-09-12 | 2013-03-21 | Sanofi | Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase |
EP2760862B1 (fr) | 2011-09-27 | 2015-10-21 | Sanofi | Dérivés d'amide d'acide 6-(4-hydroxyphényl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique utilisés comme inhibiteurs de kinase |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4046768A (en) * | 1976-06-17 | 1977-09-06 | Velsicol Chemical Corporation | 1-Thiazolyl-5-pyridylcarbonyloxyimidazolidinones |
US6320050B1 (en) * | 1999-03-29 | 2001-11-20 | Hoffmann-La Roche Inc. | Heteroaromatic glucokinase activators |
US6610846B1 (en) * | 1999-03-29 | 2003-08-26 | Hoffman-La Roche Inc. | Heteroaromatic glucokinase activators |
US6353111B1 (en) * | 1999-12-15 | 2002-03-05 | Hoffmann-La Roche Inc. | Trans olefinic glucokinase activators |
CN1176915C (zh) * | 2000-05-03 | 2004-11-24 | 霍夫曼-拉罗奇有限公司 | 炔基苯基芳香杂环的菊糖激酶激活剂 |
JP3839723B2 (ja) * | 2000-05-08 | 2006-11-01 | エフ.ホフマン−ラ ロシュ アーゲー | 置換フェニルアセトアミドおよびグルコキナーゼ活性化剤としてのその使用 |
US6489485B2 (en) * | 2000-05-08 | 2002-12-03 | Hoffmann-La Roche Inc. | Para-amine substituted phenylamide glucokinase activators |
KR100556323B1 (ko) * | 2000-07-20 | 2006-03-03 | 에프. 호프만-라 로슈 아게 | 알파-아실 및 알파-헤테로원자-치환된 벤젠 아세트아미드글루코키나제 활성화제 |
US6369232B1 (en) * | 2000-08-15 | 2002-04-09 | Hoffmann-La Roche Inc. | Tetrazolyl-phenyl acetamide glucokinase activators |
ES2256340T3 (es) * | 2000-12-06 | 2006-07-16 | F. Hoffmann-La Roche Ag | Activadores heteroaromaticos fusionados de la glucoquinasa. |
US6433188B1 (en) * | 2000-12-06 | 2002-08-13 | Wendy Lea Corbett | Fused heteroaromatic glucokinase activators |
US6482951B2 (en) * | 2000-12-13 | 2002-11-19 | Hoffmann-La Roche Inc. | Isoindolin-1-one glucokinase activators |
US6911545B2 (en) * | 2001-12-19 | 2005-06-28 | Hoffman-La Roche Inc. | Crystals of glucokinase and methods of growing them |
PL378117A1 (pl) * | 2003-02-11 | 2006-03-06 | Prosidion Limited | Tricyklopodstawione związki amidowe |
WO2004072066A1 (fr) * | 2003-02-11 | 2004-08-26 | Prosidion Limited | Composes d'amide a substitution tri(cyclo), activateurs de la glucokinase |
US20080242869A1 (en) * | 2004-04-21 | 2008-10-02 | Matthew Fyfe | Tri(Cyclo) Substituted Amide Compounds |
GB0418058D0 (en) * | 2004-08-12 | 2004-09-15 | Prosidion Ltd | Fluorination process |
GB0418046D0 (en) * | 2004-08-12 | 2004-09-15 | Prosidion Ltd | Eantioselective process |
BRPI0514147A (pt) * | 2004-08-12 | 2008-05-27 | Prosidion Ltd | composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, métodos de tratamento profilático ou terapêutico de uma condição onde a ativação de gk é desejável, de tratamento profilático ou terapêutico da hiperglicemia ou diabete e de prevenção da diabete em um ser humano que demosntra hiperglicemia pré-diabética ou toleráncia à glicose prejudicada, e, processo para a preparação do composto |
WO2007051846A1 (fr) * | 2005-11-03 | 2007-05-10 | Prosidion Ltd | Amides a substitution tricyclo |
BRPI0618062A2 (pt) * | 2005-11-03 | 2011-08-16 | Prosidion Ltd | composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, e, processo para a preparação de um composto |
US20080293741A1 (en) * | 2005-11-03 | 2008-11-27 | Matthew Colin Thor Fyfe | Tricyclo Substituted Amides as Glucokinase Modulators |
-
2009
- 2009-01-05 AR ARP090100022A patent/AR070107A1/es unknown
- 2009-01-05 PE PE2009000004A patent/PE20091313A1/es not_active Application Discontinuation
- 2009-01-05 TW TW098100066A patent/TW200934772A/zh unknown
- 2009-01-05 CL CL2009000004A patent/CL2009000004A1/es unknown
- 2009-01-07 US US12/349,552 patent/US20090181981A1/en not_active Abandoned
- 2009-01-07 AU AU2009205606A patent/AU2009205606A1/en not_active Abandoned
- 2009-01-07 KR KR1020107015579A patent/KR20100092061A/ko not_active Application Discontinuation
- 2009-01-07 WO PCT/US2009/030241 patent/WO2009091634A1/fr active Application Filing
- 2009-01-07 CN CN2009801021905A patent/CN101909629A/zh active Pending
- 2009-01-07 MX MX2010007784A patent/MX2010007784A/es not_active Application Discontinuation
- 2009-01-07 CA CA2712245A patent/CA2712245A1/fr not_active Abandoned
- 2009-01-07 EA EA201070853A patent/EA201070853A1/ru unknown
- 2009-01-07 BR BRPI0907165-2A patent/BRPI0907165A2/pt not_active IP Right Cessation
- 2009-01-07 JP JP2010542316A patent/JP2011509934A/ja not_active Withdrawn
- 2009-01-07 EP EP09701625A patent/EP2265271A1/fr not_active Withdrawn
-
2010
- 2010-05-31 IL IL206102A patent/IL206102A0/en unknown
- 2010-06-01 ZA ZA2010/03909A patent/ZA201003909B/en unknown
- 2010-06-16 MA MA32927A patent/MA31985B1/fr unknown
- 2010-06-25 TN TN2010000299A patent/TN2010000299A1/fr unknown
- 2010-07-13 DO DO2010000216A patent/DOP2010000216A/es unknown
- 2010-07-15 EC EC2010010347A patent/ECSP10010347A/es unknown
- 2010-07-29 CO CO10092662A patent/CO6280489A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ECSP10010347A (es) | 2010-09-30 |
TW200934772A (en) | 2009-08-16 |
KR20100092061A (ko) | 2010-08-19 |
EP2265271A1 (fr) | 2010-12-29 |
MX2010007784A (es) | 2010-08-09 |
ZA201003909B (en) | 2011-11-30 |
US20090181981A1 (en) | 2009-07-16 |
CL2009000004A1 (es) | 2010-02-19 |
BRPI0907165A2 (pt) | 2015-07-14 |
PE20091313A1 (es) | 2009-09-03 |
TN2010000299A1 (en) | 2011-11-11 |
CO6280489A2 (es) | 2011-05-20 |
EA201070853A1 (ru) | 2010-12-30 |
AU2009205606A1 (en) | 2009-07-23 |
IL206102A0 (en) | 2010-11-30 |
DOP2010000216A (es) | 2010-10-15 |
AR070107A1 (es) | 2010-03-17 |
CA2712245A1 (fr) | 2009-07-23 |
JP2011509934A (ja) | 2011-03-31 |
WO2009091634A1 (fr) | 2009-07-23 |
CN101909629A (zh) | 2010-12-08 |
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