MA30768B1 - Methodes d'administration d'agents hypoglycemiques a longue duree d'action - Google Patents

Methodes d'administration d'agents hypoglycemiques a longue duree d'action

Info

Publication number
MA30768B1
MA30768B1 MA31741A MA31741A MA30768B1 MA 30768 B1 MA30768 B1 MA 30768B1 MA 31741 A MA31741 A MA 31741A MA 31741 A MA31741 A MA 31741A MA 30768 B1 MA30768 B1 MA 30768B1
Authority
MA
Morocco
Prior art keywords
methods
action
long term
hypoglycemic agents
administering
Prior art date
Application number
MA31741A
Other languages
English (en)
Inventor
Mark A Bush
Jessica E Matthews
Susan E Walker
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of MA30768B1 publication Critical patent/MA30768B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA PRÉSENTE INVENTION CONCERNE DES MÉTHODES ET DES COMPOSITIONS PHARMACEUTIQUES DESTINÉES À L'ADMINISTRATION D'AGENTS HYPOGLYCÉMIQUES ET/OU D'AGONISTES DE GLP-1, CARACTÉRISÉES EN CE QU'ELLES PERMETTENT D'AUGMENTER ET/OU DE MAINTENIR LES VALEURS MOYENNES DE CONCENTRATION PLASMATIQUE MAXIMALE (CMAX) ET/OU DE SURFACE SOUS LA COURBE (AUC) DE L'AGENT HYPOGLYCÉMIQUE.
MA31741A 2006-09-13 2009-03-30 Methodes d'administration d'agents hypoglycemiques a longue duree d'action MA30768B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82547206P 2006-09-13 2006-09-13
US86839106P 2006-12-04 2006-12-04

Publications (1)

Publication Number Publication Date
MA30768B1 true MA30768B1 (fr) 2009-10-01

Family

ID=39184534

Family Applications (1)

Application Number Title Priority Date Filing Date
MA31741A MA30768B1 (fr) 2006-09-13 2009-03-30 Methodes d'administration d'agents hypoglycemiques a longue duree d'action

Country Status (25)

Country Link
US (3) US8338369B2 (fr)
EP (1) EP2073834B1 (fr)
JP (2) JP5524620B2 (fr)
KR (1) KR101472601B1 (fr)
CN (1) CN103705911A (fr)
AR (1) AR062775A1 (fr)
AU (1) AU2007296499C1 (fr)
BR (1) BRPI0716765A8 (fr)
CA (1) CA2662622C (fr)
CL (1) CL2007002634A1 (fr)
CR (1) CR10684A (fr)
EA (1) EA017159B1 (fr)
ES (1) ES2442869T3 (fr)
IL (1) IL197448A (fr)
JO (1) JO2945B1 (fr)
MA (1) MA30768B1 (fr)
MX (1) MX2009002863A (fr)
MY (1) MY149911A (fr)
NO (1) NO20091266L (fr)
NZ (1) NZ575419A (fr)
PE (2) PE20121528A1 (fr)
SG (2) SG174770A1 (fr)
TW (1) TWI430806B (fr)
WO (1) WO2008033888A2 (fr)
ZA (1) ZA200901548B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE029798T2 (en) 2005-11-04 2017-03-28 Glaxosmithkline Llc Methods of administering hypoglycemic agents
US8748377B2 (en) * 2008-12-10 2014-06-10 Glaxosmithkline Llc Pharmaceutical compositions
US8691763B2 (en) 2010-05-04 2014-04-08 Glaxosmithkline Llc Methods for treating or preventing cardiovascular disorders and providing cardiovascular protection
WO2012080471A1 (fr) 2010-12-16 2012-06-21 Novo Nordisk A/S Compositions solides comprenant un agoniste de glp-1 et un sel de l'acide n-(8-(2-hydroxybenzoyl)amino)caprylique
ES2612278T3 (es) 2011-04-12 2017-05-16 Novo Nordisk A/S Derivados de GLP-1 doble-acilados
US10933120B2 (en) 2012-03-22 2021-03-02 Novo Nordisk A/S Compositions of GLP-1 peptides and preparation thereof
ES2715308T3 (es) 2012-03-22 2019-06-03 Novo Nordisk As Composiciones que comprenden un agente de suministro y su preparación
US9993430B2 (en) 2012-06-20 2018-06-12 Novo Nordisk A/S Tablet formulation comprising semaglutide and a delivery agent
MY172578A (en) * 2013-05-02 2019-12-03 Novo Nordisk As Oral dosing of glp-1 compounds
PE20151770A1 (es) 2013-05-28 2015-12-11 Takeda Pharmaceutical Compuesto peptidico
EP3467106A4 (fr) 2016-05-24 2020-02-26 Takeda Pharmaceutical Company Limited Composé peptidique
EP3746111B1 (fr) 2018-02-02 2023-07-19 Novo Nordisk A/S Compositions solides comportant un agoniste glp-1, du sel d'acide n-(8-(2-hydroxybenzoyl)amino)caprylate et un lubrifiant
AR125086A1 (es) * 2021-03-23 2023-06-07 Lilly Co Eli Composiciones que contienen análogos de incretina y usos de estas

Family Cites Families (24)

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Publication number Priority date Publication date Assignee Title
US5545618A (en) * 1990-01-24 1996-08-13 Buckley; Douglas I. GLP-1 analogs useful for diabetes treatment
US5512549A (en) 1994-10-18 1996-04-30 Eli Lilly And Company Glucagon-like insulinotropic peptide analogs, compositions, and methods of use
ATE493998T1 (de) 1996-08-08 2011-01-15 Amylin Pharmaceuticals Inc Pharmazeutische zusammensetzung mit einem exendin-4-peptid
US6277819B1 (en) 1996-08-30 2001-08-21 Eli Lilly And Company Use of GLP-1 or analogs in treatment of myocardial infarction
US6380357B2 (en) 1997-12-16 2002-04-30 Eli Lilly And Company Glucagon-like peptide-1 crystals
JP2002523466A (ja) * 1998-08-28 2002-07-30 イーライ・リリー・アンド・カンパニー インスリン向性ペプチドの投与方法
DE60006100T2 (de) * 1999-05-17 2004-07-01 Conjuchem, Inc., Montreal Lang wirkende insulinotrope peptide
US6395767B2 (en) * 2000-03-10 2002-05-28 Bristol-Myers Squibb Company Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
PL209550B1 (pl) 2000-12-07 2011-09-30 Lilly Co Eli Heterogenne białko fuzyjne, kompozycja farmaceutyczna do leczenia pacjentów z cukrzycą insulinoniezależną i kompozycja do leczenia pacjentów z otyłością
JP2004521093A (ja) * 2000-12-13 2004-07-15 イーライ・リリー・アンド・カンパニー グルカゴン様インスリン刺激性ペプチドを用いる長期治療計画
AU2002308706A1 (en) * 2001-06-01 2002-12-16 Eli Lilly And Company Glp-1 formulations with protracted time action
AU2002322403A1 (en) * 2001-08-23 2003-03-10 Eli Lilly And Company Glucagon-like peptide-1 analogs
AR036711A1 (es) 2001-10-05 2004-09-29 Bayer Corp Peptidos que actuan como agonistas del receptor del glp-1 y como antagonistas del receptor del glucagon y sus metodos de uso farmacologico
WO2003033671A2 (fr) 2001-10-18 2003-04-24 Bristol-Myers Squibb Company Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
EP1463752A4 (fr) 2001-12-21 2005-07-13 Human Genome Sciences Inc Proteines de fusion d'albumine
EP1997829A1 (fr) * 2001-12-21 2008-12-03 Human Genome Sciences, Inc. Protéines de fusion d'albumine
WO2003058203A2 (fr) 2002-01-08 2003-07-17 Eli Lilly And Company Analogues de peptide-1 de type glucagon d'extension
CA2513213C (fr) 2003-01-22 2013-07-30 Human Genome Sciences, Inc. Proteines hybrides d'albumine
SI1689757T1 (sl) * 2003-11-12 2015-01-30 Sino-Med International Alliance, Inc. Heterociklične spojine boronske kisline
EP1704998B1 (fr) * 2004-01-13 2011-04-20 Asahi Glass Company, Limited Lamelle multicouche
SI1729795T1 (sl) 2004-02-09 2016-04-29 Human Genome Sciences, Inc. Albuminski fuzijski proteini
JP2008501765A (ja) * 2004-06-11 2008-01-24 ノボ　ノルディスク　アクティーゼルスカブ Ｇｌｐ−１アゴニストを用いた薬剤誘発性肥満の中和
HUE029798T2 (en) * 2005-11-04 2017-03-28 Glaxosmithkline Llc Methods of administering hypoglycemic agents
EP2021014A1 (fr) 2006-05-26 2009-02-11 Brystol-Myers Squibb Company Modulateurs des récepteurs de glp-1 à libération prolongée

Also Published As

Publication number Publication date
EP2073834B1 (fr) 2013-10-23
IL197448A0 (en) 2011-08-01
AR062775A1 (es) 2008-12-03
NO20091266L (no) 2009-06-09
ZA200901548B (en) 2010-02-24
US20130005652A1 (en) 2013-01-03
TW200824706A (en) 2008-06-16
BRPI0716765A2 (pt) 2013-09-24
AU2007296499B2 (en) 2013-05-02
WO2008033888A3 (fr) 2008-10-16
CN103705911A (zh) 2014-04-09
US20100009910A1 (en) 2010-01-14
EA017159B1 (ru) 2012-10-30
JP2010503697A (ja) 2010-02-04
SG174770A1 (en) 2011-10-28
IL197448A (en) 2013-06-27
MX2009002863A (es) 2009-03-30
WO2008033888A2 (fr) 2008-03-20
SG10201501749WA (en) 2015-05-28
US20140066371A1 (en) 2014-03-06
KR101472601B1 (ko) 2014-12-15
CA2662622A1 (fr) 2008-03-20
ES2442869T3 (es) 2014-02-14
MY149911A (en) 2013-10-31
TWI430806B (zh) 2014-03-21
CA2662622C (fr) 2017-01-17
AU2007296499C1 (en) 2013-09-12
JP5524620B2 (ja) 2014-06-18
EP2073834A4 (fr) 2010-11-03
JP5753924B2 (ja) 2015-07-22
NZ575419A (en) 2011-11-25
JO2945B1 (en) 2016-03-15
PE20080840A1 (es) 2008-08-27
KR20090059155A (ko) 2009-06-10
BRPI0716765A8 (pt) 2017-02-21
EA200970274A1 (ru) 2009-08-28
US8338369B2 (en) 2012-12-25
CL2007002634A1 (es) 2008-05-16
JP2014148524A (ja) 2014-08-21
EP2073834A2 (fr) 2009-07-01
PE20121528A1 (es) 2012-12-12
CR10684A (es) 2009-04-28
AU2007296499A1 (en) 2008-03-20

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