MA29088B1 - Composes d'indazole-carboxamide. - Google Patents

Composes d'indazole-carboxamide.

Info

Publication number
MA29088B1
MA29088B1 MA29976A MA29976A MA29088B1 MA 29088 B1 MA29088 B1 MA 29088B1 MA 29976 A MA29976 A MA 29976A MA 29976 A MA29976 A MA 29976A MA 29088 B1 MA29088 B1 MA 29088B1
Authority
MA
Morocco
Prior art keywords
compounds
indazole
carboxamide compounds
carboxamide
preparing
Prior art date
Application number
MA29976A
Other languages
English (en)
Inventor
Paul R Fatheree
Roland Gendron
Adam Goldblum
Daniel D Long
Daniel Marquess
Derek S Turner
Seok-Ki Choi
Original Assignee
Theravance Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theravance Inc filed Critical Theravance Inc
Publication of MA29088B1 publication Critical patent/MA29088B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
MA29976A 2004-12-22 2007-06-08 Composes d'indazole-carboxamide. MA29088B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63880004P 2004-12-22 2004-12-22

Publications (1)

Publication Number Publication Date
MA29088B1 true MA29088B1 (fr) 2007-12-03

Family

ID=36295339

Family Applications (1)

Application Number Title Priority Date Filing Date
MA29976A MA29088B1 (fr) 2004-12-22 2007-06-08 Composes d'indazole-carboxamide.

Country Status (19)

Country Link
US (3) US7419989B2 (fr)
EP (1) EP1831211B1 (fr)
JP (1) JP5159317B2 (fr)
KR (1) KR20070091665A (fr)
CN (1) CN101080406A (fr)
AT (1) ATE469897T1 (fr)
AU (1) AU2005319190A1 (fr)
BR (1) BRPI0519708A2 (fr)
CA (1) CA2588037A1 (fr)
DE (1) DE602005021696D1 (fr)
ES (1) ES2347265T3 (fr)
IL (1) IL183160A0 (fr)
MA (1) MA29088B1 (fr)
MX (1) MX2007007818A (fr)
NO (1) NO20073182L (fr)
NZ (1) NZ555180A (fr)
RU (1) RU2404179C2 (fr)
WO (1) WO2006069125A1 (fr)
ZA (1) ZA200705115B (fr)

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EP1902053B1 (fr) * 2005-06-07 2011-01-12 Theravance, Inc. Composes de benzoimidazolone-carboxamide en tant qu'agonistes du recepteur 5-ht4
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US20160024057A1 (en) * 2014-07-25 2016-01-28 Innov17 Llc Indazole retinoic acid receptor-related orphan receptor modulators and uses thereof
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WO2019058393A1 (fr) 2017-09-22 2019-03-28 Jubilant Biosys Limited Composés hétérocycliques en tant qu'inhibiteurs de pad
SG11202003463XA (en) 2017-10-18 2020-05-28 Jubilant Epipad LLC Imidazo-pyridine compounds as pad inhibitors
CN111386265A (zh) 2017-11-06 2020-07-07 朱比连特普罗德尔有限责任公司 作为pd1/pd-l1活化的抑制剂的嘧啶衍生物
MX2020005363A (es) 2017-11-24 2020-10-01 Jubilant Episcribe Llc Compuestos heterociclicos como inhibidores de prmt5.
EP3765453A1 (fr) 2018-03-13 2021-01-20 Jubilant Prodel LLC Composés bicycliques utilisés en tant qu'inhibiteurs de l'interaction/activation de pd1/pd-l1
JP2020199139A (ja) * 2019-06-12 2020-12-17 コニカミノルタ株式会社 制御装置、放射線撮影システム、制御方法及びプログラム
CN112805282A (zh) * 2019-09-12 2021-05-14 广东东阳光药业有限公司 吲唑-甲酰胺衍生物及其用途

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Also Published As

Publication number Publication date
RU2404179C2 (ru) 2010-11-20
US20080132491A1 (en) 2008-06-05
EP1831211A1 (fr) 2007-09-12
WO2006069125A1 (fr) 2006-06-29
US7786136B2 (en) 2010-08-31
CN101080406A (zh) 2007-11-28
US7419989B2 (en) 2008-09-02
US20100292223A1 (en) 2010-11-18
IL183160A0 (en) 2007-09-20
JP5159317B2 (ja) 2013-03-06
BRPI0519708A2 (pt) 2009-03-10
AU2005319190A1 (en) 2006-06-29
MX2007007818A (es) 2007-09-11
KR20070091665A (ko) 2007-09-11
ZA200705115B (en) 2008-06-25
US20060135764A1 (en) 2006-06-22
ES2347265T3 (es) 2010-10-27
NZ555180A (en) 2010-09-30
JP2008525466A (ja) 2008-07-17
NO20073182L (no) 2007-08-28
RU2007128061A (ru) 2009-01-27
CA2588037A1 (fr) 2006-06-29
US8003664B2 (en) 2011-08-23
EP1831211B1 (fr) 2010-06-02
ATE469897T1 (de) 2010-06-15
DE602005021696D1 (de) 2010-07-15

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