MA26353A1 - Procede pour la preparation de 3-{2-[4-(6-fluorobenzo[d] isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-4h-pyrido-[1,2-a]pyrimidin-4-one - Google Patents

Procede pour la preparation de 3-{2-[4-(6-fluorobenzo[d] isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-4h-pyrido-[1,2-a]pyrimidin-4-one

Info

Publication number
MA26353A1
MA26353A1 MA27800A MA27800A MA26353A1 MA 26353 A1 MA26353 A1 MA 26353A1 MA 27800 A MA27800 A MA 27800A MA 27800 A MA27800 A MA 27800A MA 26353 A1 MA26353 A1 MA 26353A1
Authority
MA
Morocco
Prior art keywords
fluorobenzo
isoxazol
pyrido
pyrimidin
piperidin
Prior art date
Application number
MA27800A
Other languages
English (en)
Inventor
Rafael Foguet
Jorge Ramentol
Diego Fernandez-Cano
Miguel P Armengol
Francesc X Camps
Juan Sallares
Ines Petschen
Mireia Pasto
Esther Gordo
Original Assignee
Ferrer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Int filed Critical Ferrer Int
Publication of MA26353A1 publication Critical patent/MA26353A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
MA27800A 2002-03-05 2004-07-27 Procede pour la preparation de 3-{2-[4-(6-fluorobenzo[d] isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-4h-pyrido-[1,2-a]pyrimidin-4-one MA26353A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200200531A ES2197801B1 (es) 2002-03-05 2002-03-05 Procedimiento de obtencion de la 3-(2-(4-(6-fluoro-benzo(d)isoxazol-3-il) piperidin-1-il)-etil)-2-metil-6,7,8,9-tetrahidro-4h-pirido-(1,2-a ) pirimidin-4-ona.

Publications (1)

Publication Number Publication Date
MA26353A1 true MA26353A1 (fr) 2004-10-01

Family

ID=27772022

Family Applications (1)

Application Number Title Priority Date Filing Date
MA27800A MA26353A1 (fr) 2002-03-05 2004-07-27 Procede pour la preparation de 3-{2-[4-(6-fluorobenzo[d] isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-4h-pyrido-[1,2-a]pyrimidin-4-one

Country Status (22)

Country Link
US (1) US7205405B2 (fr)
EP (1) EP1480978A1 (fr)
JP (1) JP2005525366A (fr)
KR (1) KR100680003B1 (fr)
CN (1) CN1315826C (fr)
AU (1) AU2003219010A1 (fr)
BR (1) BR0308139A (fr)
CA (1) CA2474811A1 (fr)
CO (1) CO5611140A2 (fr)
CR (1) CR7462A (fr)
ES (1) ES2197801B1 (fr)
IL (1) IL163750A0 (fr)
MA (1) MA26353A1 (fr)
MX (1) MXPA04008289A (fr)
NO (1) NO20043447L (fr)
NZ (1) NZ534463A (fr)
PL (1) PL370502A1 (fr)
RU (1) RU2272037C9 (fr)
TN (1) TNSN04139A1 (fr)
UA (1) UA80114C2 (fr)
WO (1) WO2003074522A1 (fr)
ZA (1) ZA200405939B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0214716B8 (pt) * 2001-12-05 2021-05-25 Teva Womens Health Inc kit, preparos, e uso de estrogênio e progestina na fabricação de um medicamento para uso na prevenção de gravidez
KR20040025224A (ko) * 2002-09-18 2004-03-24 주식회사 대웅 2-(2-메틸-4-옥소-6,7,8,9-테트라하이드로-4Ｈ-피리도[1,2-ａ]피리미딘-3-일)아세트알데히드 및 그 제조방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4804663A (en) * 1985-03-27 1989-02-14 Janssen Pharmaceutica N.V. 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
CA2000786C (fr) * 1988-11-07 1999-01-26 Cornelus G. M. Janssen 3-piperidinyl-1,2-benzisoxazoles
GB9008850D0 (en) * 1990-04-19 1990-06-13 Janssen Pharmaceutica Nv Novel 2,9-disubstituted-4h-pyridol(1,2-a)pyrimidin-4-ones
CZ295402B6 (cs) * 2000-05-05 2005-08-17 Rpg Life Sciences Limited Způsob přípravy antipsychotického 3-[2-[4-(6-fluor-1,2-benzizoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2,-a]pyrimidin-4-onu

Also Published As

Publication number Publication date
MXPA04008289A (es) 2004-11-26
IL163750A0 (en) 2005-12-18
NZ534463A (en) 2006-02-24
JP2005525366A (ja) 2005-08-25
KR100680003B1 (ko) 2007-02-08
UA80114C2 (en) 2007-08-27
ES2197801A1 (es) 2004-01-01
ES2197801B1 (es) 2005-03-16
CA2474811A1 (fr) 2003-09-12
WO2003074522A1 (fr) 2003-09-12
PL370502A1 (en) 2005-05-30
KR20040091679A (ko) 2004-10-28
CR7462A (es) 2005-02-10
ZA200405939B (en) 2006-06-28
RU2272037C1 (ru) 2006-03-20
NO20043447L (no) 2004-08-18
CN1315826C (zh) 2007-05-16
BR0308139A (pt) 2005-01-04
CN1639163A (zh) 2005-07-13
TNSN04139A1 (en) 2007-03-12
US7205405B2 (en) 2007-04-17
CO5611140A2 (es) 2006-02-28
RU2272037C9 (ru) 2006-06-20
US20050143395A1 (en) 2005-06-30
AU2003219010A1 (en) 2003-09-16
EP1480978A1 (fr) 2004-12-01

Similar Documents

Publication Publication Date Title
ATE284214T1 (de) Imidazo(1,2-a)-pyridinderivate als mglur5 antagonisten
LTC1470124I2 (lt) 2-(Piridin-2-ilamino)-pirido[2,3-d]piridin-7-onai
TWI377063B (en) Crystalline forms of pemetrexed diacid and processes for the preparation thereof
NO20055588D0 (no) Pyrimidinderivater anvendelige for behandling av sykdommer mediert av CRTH2
WO2008024415A8 (fr) Procédé destiné à la synthèse de cmhtp et de ses intermédiaires
PL1611144T3 (pl) Pochodne kwasu 2-(8,9-diokso-2,6-diazabicyklo(5.2.0)non-1(7)-en-2-ylo)alkilofosfonowego i ich zastosowanie jako antagonistów receptora N-metylo-D-asparaginianu (NMDA)
FI911885A (fi) Menetelmä terapeuttisesti käyttökelpoisten 2,9-disubstituoitujen 3-/2-/4-(6-fluori-1,2-bentsisoksatsol-3-yyli)-piperidinyyli/etyyli/-4H-pyrido/1,2-a/pyrimidin-4-onien valmistamiseksi
SI1534707T1 (sl) Substituirani derivati 2,4-dihidro-pirolo(3,4-b)kinolin-9-ona, uporabni kot fosfodiesterazni inhibitorji
ATE325117T1 (de) 3,4-dihydrochinolin-2(1h)-on verbindungen als nr2b rezeptor antagonisten
MA26353A1 (fr) Procede pour la preparation de 3-{2-[4-(6-fluorobenzo[d] isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-4h-pyrido-[1,2-a]pyrimidin-4-one
IS1766B (is) Aðferð við að fá fram 3-{2-[4-(6-flúor-bensó[D]isoxasól-3-ýl)píperidín-1-ýl]-etýl}-2-metýl-6,7,8,9-fjórhýdró-4H-pýridó[1,2-A]pýrimidín-4-on
NO20073758L (no) 2-okso-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl-piperidiner anvendt som CGRP-antagonister
HUP0104873A3 (en) Refined process for the preparation of 3-{2-[4-(6-fluoro-1,2-benzizoxazol-3-yl)-1-piperidinyl]-ethyl}-6,7,8,9-tetrahydro-2-methyl-4h-pyrido[1,2-a]pyrimidin-4-one
FR2873686B1 (fr) Procede d'obtention de ceramiques poreuses
IL184781A0 (en) CRYSTALLINE 1H-IMIDAZO[4,5-b]PYRIDIN-5-AMINE, 7-[5-[(CYCLOHEXYLMETHYLAMINO)-METHYL]-1H-INDOL-2-YL]-2-METHYL, SULFATE (1:1), TRIHYDRATE AND ITS PHARMACEUTICAL USES
SI1461338T1 (sl) Izboljšan postopek za pripravo 3-(2-(4-(6-fluoro-1,2-benzizoksazol-3-il)-1-piperidinil)etil)-6,7, 8,9-tetrahidro-2-metil-4H-pirido(1,2-A)pirimidin-4-ona
AU2002363610A1 (en) Improved process for the preparation of 3-{2-`4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl!ethyl}-6,7,8,9-tetrahydro-2-methyl-4h-pyrido`1,2-a!pyrimidin-4-one
DK1497290T3 (da) Fremgangsmåde til fremstilling af syresalte af gemifloxacin
SE0100297D0 (sv) New compounds
FR2853315B1 (fr) Procede pour la fabrication de derives d'aminoacides
GB0308892D0 (en) Process for the preparation of 2-[4-(4-flurophenyl)-5-12-(methylthio)-4-pyrimidinyl]-1H-imidazol-2yl]-5-me thyl-trans-1,3-dioxane-5-carboxylic acid
FR2843391B1 (fr) Procede de preparation d'halogenoalkyldialkylchlorosilane
NO20053047D0 (no) Fremgangsmate for fremstilling av inhibitorer av fosfodiesterase4
SI1611144T1 (sl) Derivati 2-(8,9-diokso-2,6-diazabiciklo(5.2.0)non-1(7)-en-2-il)alkil fosfonske kisline in njihova uporaba kot antagonisti N-metil-D-aspartat(NMDA) receptorja
ITMO20020177A1 (it) Apparato per la formatura di manufatti ceramici