LV12375B - 1- (3-AMINOINDADAZOL-5-IL) -FENILMETIL) - CYCLIC UREA SUITABLE AS HIV PROTEAS INHIBITORS - Google Patents

1- (3-AMINOINDADAZOL-5-IL) -FENILMETIL) - CYCLIC UREA SUITABLE AS HIV PROTEAS INHIBITORS Download PDF

Info

Publication number
LV12375B
LV12375B LVP-99-76A LV990076A LV12375B LV 12375 B LV12375 B LV 12375B LV 990076 A LV990076 A LV 990076A LV 12375 B LV12375 B LV 12375B
Authority
LV
Latvia
Prior art keywords
compound
formula
hiv
quot
reverse transcriptase
Prior art date
Application number
LVP-99-76A
Other languages
English (en)
Latvian (lv)
Other versions
LV12375A (lv
Inventor
James David Rodgers
Robert Frank Kaltenbach, Iii
Original Assignee
Dupont Pharmaceuticals Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dupont Pharmaceuticals Company filed Critical Dupont Pharmaceuticals Company
Publication of LV12375A publication Critical patent/LV12375A/xx
Publication of LV12375B publication Critical patent/LV12375B/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • AIDS & HIV (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
LVP-99-76A 1996-11-08 1999-04-29 1- (3-AMINOINDADAZOL-5-IL) -FENILMETIL) - CYCLIC UREA SUITABLE AS HIV PROTEAS INHIBITORS LV12375B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2974596P 1996-11-08 1996-11-08
US74710496A 1996-11-08 1996-11-08
PCT/US1997/020035 WO1998020008A1 (fr) 1996-11-08 1997-11-04 Urees 1-(3-aminoindazol-5-yl)-3-phenylmethyl-cycliques utiles en tant qu'inhibiteurs de protease de vih

Publications (2)

Publication Number Publication Date
LV12375A LV12375A (lv) 1999-11-20
LV12375B true LV12375B (en) 2000-04-20

Family

ID=26705293

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-99-76A LV12375B (en) 1996-11-08 1999-04-29 1- (3-AMINOINDADAZOL-5-IL) -FENILMETIL) - CYCLIC UREA SUITABLE AS HIV PROTEAS INHIBITORS

Country Status (21)

Country Link
EP (1) EP0937067B1 (fr)
JP (1) JP2001503428A (fr)
KR (1) KR20000053122A (fr)
CN (1) CN1235602A (fr)
AT (1) ATE244714T1 (fr)
AU (1) AU5165198A (fr)
BR (1) BR9712910A (fr)
CA (1) CA2270966A1 (fr)
CZ (1) CZ157599A3 (fr)
DE (1) DE69723456T2 (fr)
EA (1) EA199900452A1 (fr)
EE (1) EE9900188A (fr)
ES (1) ES2202645T3 (fr)
HU (1) HUP9904676A2 (fr)
IL (1) IL129727A0 (fr)
LV (1) LV12375B (fr)
NO (1) NO992228L (fr)
PL (1) PL333421A1 (fr)
SI (1) SI20074A (fr)
SK (1) SK59699A3 (fr)
WO (1) WO1998020008A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6870098A (en) * 1997-03-31 1998-10-22 Du Pont Merck Pharmaceutical Company, The Indazoles of cyclic ureas useful as hiv protease inhibitors
US7135575B2 (en) 2003-03-03 2006-11-14 Array Biopharma, Inc. P38 inhibitors and methods of use thereof
CN101415685B (zh) 2006-01-31 2011-08-24 阿雷生物药品公司 激酶抑制剂及其使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5610294A (en) * 1991-10-11 1997-03-11 The Du Pont Merck Pharmaceutical Company Substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors
US5532357A (en) * 1995-06-07 1996-07-02 The Dupont Merck Pharmaceutical Company Method for preparing N-monosubstituted and N,N'-disubstituted unsymmetrical cyclic ureas

Also Published As

Publication number Publication date
KR20000053122A (ko) 2000-08-25
EP0937067A1 (fr) 1999-08-25
EP0937067B1 (fr) 2003-07-09
DE69723456T2 (de) 2004-05-27
ATE244714T1 (de) 2003-07-15
DE69723456D1 (de) 2003-08-14
EE9900188A (et) 1999-12-15
BR9712910A (pt) 2000-03-21
LV12375A (lv) 1999-11-20
PL333421A1 (en) 1999-12-06
ES2202645T3 (es) 2004-04-01
CA2270966A1 (fr) 1998-05-14
AU5165198A (en) 1998-05-29
IL129727A0 (en) 2000-02-29
EA199900452A1 (ru) 2000-02-28
CZ157599A3 (cs) 1999-11-17
WO1998020008A1 (fr) 1998-05-14
NO992228L (no) 1999-06-07
CN1235602A (zh) 1999-11-17
NO992228D0 (no) 1999-05-07
SK59699A3 (en) 1999-12-10
HUP9904676A2 (hu) 2000-06-28
JP2001503428A (ja) 2001-03-13
SI20074A (sl) 2000-04-30

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