LV11782B - Treatment of ovarian estrogen dependent conditions - Google Patents
Treatment of ovarian estrogen dependent conditions Download PDFInfo
- Publication number
- LV11782B LV11782B LVP-96-354A LV960354A LV11782B LV 11782 B LV11782 B LV 11782B LV 960354 A LV960354 A LV 960354A LV 11782 B LV11782 B LV 11782B
- Authority
- LV
- Latvia
- Prior art keywords
- antiprogestin
- preparation according
- treatment
- estrogen
- administration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Claims (10)
- LV 11782 IZGUDROJUMA FORMULA 1. Preparāts ārstēšanai no olnīcu estrogēniem atkarīgā stāvokļa, kas satur kombināciju no gonadotropīnu liberīna analoga un antiprogestīna, kurā gonadotropīnu liberīna analogs tiek pielietots tādā daudzumā, kas ir pietiekams asinīs cirkulējošo estrogēnu līmeņa samazināšanai līdz aptuveni 20 pg/ml vai mazāk, bet antiprogestīns - antiproliferatīvā un kaulu audu saglabājošā daudzumā.
- 2. Preparāts saskaņā ar 1. punktu, kas raksturojas ar to, ka minētais analogs ir gonadotropīnu liberīna agonists.
- 3. Preparāts saskaņā ar 1. punktu, kas raksturojas arto, ka minētais analogs ir gonadotropīnu liberīna antagonists.
- 4. Preparāts saskaņā ar 1. punktu, kas raksturojas ar to, ka gonadotropīnu liberīna analogu pielieto, lai samazinātu asins apritē esošo estrogēnu līmeni līdz aptuveni 10 pg/ml vai mazāk.
- 5. Preparāts saskaņā ar 1. punktu, kas raksturojas arto, ka antiprogestīns ir progestīna receptoru antagonists.
- 6. Preparāts saskaņā ar 1. punktu, kas raksturojas arto, ka antiprogestīns ir mifepristons.
- 7. Preparāts saskaņā ar 1. punktu, kas raksturojas arto, ka antiprogestīna daudzums ir pietiekams, lai iegūtu noturīgu amenorejas stāvokli.
- 8. Preparāts saskaņā ar 1. punktu, kas raksturojas ar to, ka stāvoklis, kas ir atkarīgs no olnīcu estrogēniem, ir endometrioze.
- 9. Preparāts saskaņā ar 1. punktu, kas raksturojas arto, ka stāvoklis, kas ir atkarīgs no olnīcu estrogēniem, ir dzemdes leiomioma.
- 10. Preparāts saskaņā ar 1. punktu, kas raksturojas arto, ka stāvoklis, kas ir atkarīgs no olnīcu estrogēniem, ir pirmsmenstruālais sindroms. 1.1. Preparāts saskaņā ar 1. punktu, kas raksturojas arto, ka stāvoklis, kas ir atkarīgs no olnīcu estrogēniem, ir disfunkcionālā dzemdes asiņošana.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/191,631 US5681817A (en) | 1994-02-04 | 1994-02-04 | Treatment of ovarian estrogen dependent conditions |
PCT/US1995/001479 WO1995020972A1 (en) | 1994-02-04 | 1995-02-02 | Treatment of ovarian estrogen dependent conditions |
Publications (2)
Publication Number | Publication Date |
---|---|
LV11782A LV11782A (lv) | 1997-06-20 |
LV11782B true LV11782B (en) | 1997-12-20 |
Family
ID=22706258
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LVP-96-354A LV11782B (en) | 1994-02-04 | 1996-09-03 | Treatment of ovarian estrogen dependent conditions |
Country Status (29)
Country | Link |
---|---|
US (1) | US5681817A (lv) |
EP (1) | EP0785792B1 (lv) |
JP (1) | JP3130048B2 (lv) |
KR (1) | KR970700507A (lv) |
CN (1) | CN1144486A (lv) |
AP (1) | AP724A (lv) |
AT (1) | ATE179610T1 (lv) |
AU (1) | AU689229B2 (lv) |
BG (1) | BG62238B1 (lv) |
BR (1) | BR9506606A (lv) |
CA (1) | CA2182183C (lv) |
CZ (1) | CZ291709B6 (lv) |
DE (1) | DE69509544T2 (lv) |
DK (1) | DK0785792T3 (lv) |
ES (1) | ES2132645T3 (lv) |
FI (1) | FI963036A0 (lv) |
GR (1) | GR3030164T3 (lv) |
HU (1) | HUT74622A (lv) |
LT (1) | LT4182B (lv) |
LV (1) | LV11782B (lv) |
MD (1) | MD1432C2 (lv) |
NZ (1) | NZ281441A (lv) |
OA (1) | OA10777A (lv) |
PL (1) | PL178273B1 (lv) |
RO (1) | RO117420B1 (lv) |
RU (1) | RU2110274C1 (lv) |
SK (1) | SK96296A3 (lv) |
TJ (1) | TJ242B (lv) |
WO (1) | WO1995020972A1 (lv) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1137722C (zh) * | 1994-07-22 | 2004-02-11 | 汉普顿路医学院 | 为长期治疗方案确立基础(tonic)卵巢雌激素分泌 |
US5780435A (en) * | 1995-12-15 | 1998-07-14 | Praecis Pharmaceuticals Incorporated | Methods for treating prostate cancer with LHRH-R antagonists |
EP1029868A4 (en) | 1997-10-17 | 2003-10-22 | Mochida Pharm Co Ltd | AGENT AGAINST HYSTEROMYOMAS CONTAINS DIENOGEST AS AN ACTIVE SUBSTANCE |
US6703367B1 (en) | 1999-04-27 | 2004-03-09 | Praecis Pharmaceuticals Inc. | Methods for treating hot flashes and gynaecomastia |
US6444668B1 (en) | 1999-05-04 | 2002-09-03 | Wyeth | Combination regimens using progesterone receptor modulators |
US6369056B1 (en) | 1999-05-04 | 2002-04-09 | American Home Products Corporation | Cyclic urea and cyclic amide derivatives |
US6319912B1 (en) | 1999-05-04 | 2001-11-20 | American Home Products Corporation | Cyclic regimens using 2,1-benzisothiazoline 2,2-dioxides |
US6417214B1 (en) | 1999-05-04 | 2002-07-09 | Wyeth | 3,3-substituted indoline derivatives |
US6358947B1 (en) | 1999-05-04 | 2002-03-19 | American Home Products Corporation | Tetracyclic progesterone receptor modulator compounds and methods |
US6306851B1 (en) | 1999-05-04 | 2001-10-23 | American Home Products Corporation | Cyclocarbamate and cyclic amide derivatives |
US6391907B1 (en) | 1999-05-04 | 2002-05-21 | American Home Products Corporation | Indoline derivatives |
US6380235B1 (en) | 1999-05-04 | 2002-04-30 | American Home Products Corporation | Benzimidazolones and analogues |
US6509334B1 (en) | 1999-05-04 | 2003-01-21 | American Home Products Corporation | Cyclocarbamate derivatives as progesterone receptor modulators |
US6380178B1 (en) | 1999-05-04 | 2002-04-30 | American Home Products Corporation | Cyclic regimens using cyclocarbamate and cyclic amide derivatives |
US6339098B1 (en) | 1999-05-04 | 2002-01-15 | American Home Products Corporation | 2,1-benzisothiazoline 2,2-dioxides |
US6358948B1 (en) | 1999-05-04 | 2002-03-19 | American Home Products Corporation | Quinazolinone and benzoxazine derivatives as progesterone receptor modulators |
US6355648B1 (en) * | 1999-05-04 | 2002-03-12 | American Home Products Corporation | Thio-oxindole derivatives |
US6329416B1 (en) | 1999-05-04 | 2001-12-11 | American Home Products Corporation | Combination regimens using 3,3-substituted indoline derivatives |
US6399593B1 (en) | 1999-05-04 | 2002-06-04 | Wyeth | Cyclic regimens using cyclic urea and cyclic amide derivatives |
US6407101B1 (en) | 1999-05-04 | 2002-06-18 | American Home Products Corporation | Cyanopyrroles |
US6462032B1 (en) | 1999-05-04 | 2002-10-08 | Wyeth | Cyclic regimens utilizing indoline derivatives |
US6423699B1 (en) | 1999-05-04 | 2002-07-23 | American Home Products Corporation | Combination therapies using benzimidazolones |
US6498154B1 (en) | 1999-05-04 | 2002-12-24 | Wyeth | Cyclic regimens using quinazolinone and benzoxazine derivatives |
PT1229906E (pt) * | 1999-08-31 | 2008-01-18 | Bayer Schering Pharma Ag | Mesoprogestinas para o tratamento e prevenção de distúrbios ginecológicos hormonodependentes benignos |
US8193252B1 (en) | 1999-08-31 | 2012-06-05 | Bayer Pharma AG | Mesoprogestins (progesterone receptor modulators) for the treatment and prevention of benign hormone dependent gynecological disorders |
UA73119C2 (en) * | 2000-04-19 | 2005-06-15 | American Home Products Corpoir | Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors |
AU2001295359A1 (en) * | 2000-10-30 | 2002-05-15 | University Of Zurich | GnRH analogues for treatment of urinary incontinence |
US7029657B2 (en) * | 2002-08-02 | 2006-04-18 | Balance Pharmaceuticals, Inc. | Nasal spray steroid formulation and method |
US6958142B2 (en) * | 2002-08-02 | 2005-10-25 | Balance Pharmaceuticals, Inc. | Nasal spray formulation and method |
US6960337B2 (en) * | 2002-08-02 | 2005-11-01 | Balance Pharmaceuticals, Inc. | Methods and compositions for treating benign gynecological disorders |
GB0302572D0 (en) | 2003-02-05 | 2003-03-12 | Astrazeneca Ab | Method of treatment |
EP2316441A1 (en) * | 2005-02-17 | 2011-05-04 | Hadasit Medical Research Services And Development | Bisphosphonates for treating endometriosis |
US7862552B2 (en) | 2005-05-09 | 2011-01-04 | Boston Scientific Scimed, Inc. | Medical devices for treating urological and uterine conditions |
US20060251581A1 (en) * | 2005-05-09 | 2006-11-09 | Mcintyre Jon T | Method for treatment of uterine fibroid tumors |
SI3263112T1 (sl) * | 2006-10-24 | 2020-10-30 | Allergan Pharmaceuticals International Limited | Sestavki in metode za zaviranje endometrijskih proliferacij |
TWI455716B (zh) * | 2006-10-24 | 2014-10-11 | Repros Therapeutics Inc | 選擇性黃體激素受體調節劑用於製造治療雌激素依賴性病症之藥物的用途 |
WO2008144143A1 (en) * | 2007-05-14 | 2008-11-27 | Drugtech Corporation | Endometriosis treatment |
EP2197415B1 (en) * | 2007-09-20 | 2014-03-05 | Lapidot Medical Import And Marketing Ltd | Compositions and means for treating uterine leiomyomata, leiomyoma, myoma, uterine fibroids, endrometriosis, adenomyosis and related disorders by mifepristone |
RU2359684C1 (ru) * | 2008-01-23 | 2009-06-27 | Закрытое акционерное общество "СКАЙ ЛТД" | Способ лечения эндометриоза |
US9993427B2 (en) | 2013-03-14 | 2018-06-12 | Biorest Ltd. | Liposome formulation and manufacture |
KR101585221B1 (ko) | 2014-02-27 | 2016-01-13 | 권희완 | 지압대 겸용 지압 베개 |
EP3560555A1 (en) * | 2018-04-26 | 2019-10-30 | LifeArc | A composition for treating one or more estrogen related diseases |
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ZA8231B (en) | 1981-01-09 | 1982-11-24 | Roussel Uclaf | New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained |
US4780461A (en) | 1983-06-15 | 1988-10-25 | Schering Aktiengesellschaft | 13α-alkyl-gonanes, their production, and pharmaceutical preparations containing same |
DE3347126A1 (de) | 1983-12-22 | 1985-07-11 | Schering AG, 1000 Berlin und 4709 Bergkamen | 11ss-aryl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate |
ATE86484T1 (de) | 1987-08-08 | 1993-03-15 | Akzo Nv | Kontrazeptives implantat. |
DE3744054A1 (de) | 1987-12-21 | 1989-06-29 | Schering Ag | Verwendung von antigestagenen zur herstellung von arzneimitteln |
DE3921059A1 (de) | 1989-06-23 | 1991-01-10 | Schering Ag | 11(beta)-aryl-4-estrene, verfahren zu ihrer herstellung sowie deren verwendung als arzneimittel |
JP3112172B2 (ja) | 1990-03-16 | 2000-11-27 | アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ ベノートスハップ | 多嚢胞卵巣疾病の治療 |
US6827050B2 (en) | 2001-12-21 | 2004-12-07 | Caterpillar Inc | Fluid control valve actuating system |
US7283632B2 (en) | 2003-09-09 | 2007-10-16 | The Boeing Company | Unauthorized access embedded software protection system |
-
1994
- 1994-02-04 US US08/191,631 patent/US5681817A/en not_active Expired - Fee Related
-
1995
- 1995-02-02 BR BR9506606A patent/BR9506606A/pt not_active Application Discontinuation
- 1995-02-02 DK DK95910179T patent/DK0785792T3/da active
- 1995-02-02 RU RU96118109A patent/RU2110274C1/ru active
- 1995-02-02 TJ TJ96000402A patent/TJ242B/xx unknown
- 1995-02-02 CZ CZ19962103A patent/CZ291709B6/cs not_active IP Right Cessation
- 1995-02-02 AT AT95910179T patent/ATE179610T1/de not_active IP Right Cessation
- 1995-02-02 KR KR1019960704226A patent/KR970700507A/ko not_active Application Discontinuation
- 1995-02-02 ES ES95910179T patent/ES2132645T3/es not_active Expired - Lifetime
- 1995-02-02 NZ NZ281441A patent/NZ281441A/en unknown
- 1995-02-02 WO PCT/US1995/001479 patent/WO1995020972A1/en active IP Right Grant
- 1995-02-02 CN CN95192252A patent/CN1144486A/zh active Pending
- 1995-02-02 AU AU18386/95A patent/AU689229B2/en not_active Ceased
- 1995-02-02 HU HU9601969A patent/HUT74622A/hu unknown
- 1995-02-02 EP EP95910179A patent/EP0785792B1/en not_active Expired - Lifetime
- 1995-02-02 MD MD96-0323A patent/MD1432C2/ro unknown
- 1995-02-02 SK SK962-96A patent/SK96296A3/sk unknown
- 1995-02-02 RO RO96-01583A patent/RO117420B1/ro unknown
- 1995-02-02 PL PL95315792A patent/PL178273B1/pl not_active IP Right Cessation
- 1995-02-02 CA CA002182183A patent/CA2182183C/en not_active Expired - Fee Related
- 1995-02-02 JP JP07520794A patent/JP3130048B2/ja not_active Expired - Fee Related
- 1995-02-02 DE DE69509544T patent/DE69509544T2/de not_active Expired - Fee Related
- 1995-02-02 AP APAP/P/1996/000840A patent/AP724A/en active
-
1996
- 1996-07-29 OA OA60870A patent/OA10777A/en unknown
- 1996-08-01 BG BG100766A patent/BG62238B1/bg unknown
- 1996-08-01 FI FI963036A patent/FI963036A0/fi not_active IP Right Cessation
- 1996-09-03 LV LVP-96-354A patent/LV11782B/en unknown
- 1996-09-04 LT LT96-133A patent/LT4182B/lt not_active IP Right Cessation
-
1999
- 1999-05-07 GR GR990401145T patent/GR3030164T3/el unknown
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