LV10951B - 4-quinolinyl derivatives with anti-helicobacter activity - Google Patents

4-quinolinyl derivatives with anti-helicobacter activity Download PDF

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Publication number
LV10951B
LV10951B LVP-95-143A LV950143A LV10951B LV 10951 B LV10951 B LV 10951B LV 950143 A LV950143 A LV 950143A LV 10951 B LV10951 B LV 10951B
Authority
LV
Latvia
Prior art keywords
formula
compounds
compound
vvas
acid
Prior art date
Application number
LVP-95-143A
Other languages
English (en)
Latvian (lv)
Other versions
LV10951A (lv
Inventor
Marc Gaston Venet
Jerome Emiles Georges Guillemont
Daniel Franck Jean Vernier
Franck Christopher Odds
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of LV10951A publication Critical patent/LV10951A/xx
Publication of LV10951B publication Critical patent/LV10951B/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
LVP-95-143A 1992-10-27 1995-05-26 4-quinolinyl derivatives with anti-helicobacter activity LV10951B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96700892A 1992-10-27 1992-10-27
US6980493A 1993-06-01 1993-06-01
PCT/EP1993/002884 WO1994010164A1 (en) 1992-10-27 1993-10-19 4-quinolinyl derivatives with anti-helicobacter activity

Publications (2)

Publication Number Publication Date
LV10951A LV10951A (lv) 1995-12-20
LV10951B true LV10951B (en) 1996-08-20

Family

ID=26750446

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-95-143A LV10951B (en) 1992-10-27 1995-05-26 4-quinolinyl derivatives with anti-helicobacter activity

Country Status (22)

Country Link
US (1) US5589484A (de)
EP (1) EP0666855B1 (de)
JP (1) JPH08502503A (de)
KR (1) KR100239003B1 (de)
AT (1) ATE143013T1 (de)
AU (1) AU675087B2 (de)
BG (1) BG99566A (de)
CA (1) CA2146651A1 (de)
CZ (1) CZ287159B6 (de)
DE (1) DE69304930T2 (de)
DK (1) DK0666855T3 (de)
ES (1) ES2094567T3 (de)
FI (1) FI951996A (de)
GR (1) GR3021690T3 (de)
HU (1) HUT71895A (de)
LV (1) LV10951B (de)
NO (1) NO951588L (de)
NZ (1) NZ256871A (de)
PL (1) PL175679B1 (de)
RU (1) RU2130933C1 (de)
SK (1) SK53495A3 (de)
WO (1) WO1994010164A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6479514B1 (en) 1998-05-23 2002-11-12 Altana Pharma Ag Quinoline-aminomethyl-pyridyl derivatives with anti-helicobacter activity
GB9819382D0 (en) 1998-09-04 1998-10-28 Cerebrus Ltd Chemical compounds I
TW200803855A (en) * 2006-02-24 2008-01-16 Kalypsys Inc Quinolones useful as inducible nitric oxide synthase inhibitors
US8987315B2 (en) 2009-12-31 2015-03-24 Innocrin Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
KR101802048B1 (ko) * 2013-04-02 2017-12-28 안지 파마슈티컬 코퍼레이션 리미티드 항신경퇴행성제로서의 다작용성 퀴놀린 유도체
US9302992B2 (en) 2013-04-02 2016-04-05 Annji Pharmaceutical Co., Ltd. Multifunctional quinoline derivatives as anti-neurodegenerative agents
JP6254239B2 (ja) * 2016-02-29 2017-12-27 大日精化工業株式会社 ポリマーの製造方法
JP6245719B1 (ja) 2017-03-24 2017-12-13 大日精化工業株式会社 ポリマーの製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8827822D0 (en) * 1988-11-29 1988-12-29 Janssen Pharmaceutica Nv (1h-azol-1-ylmethyl)substituted quinoline derivatives
US5185346A (en) * 1988-11-29 1993-02-09 Hanssen Pharmaceutica (1H-azol-1-ylmethyl)substituted quinoline derivatives
GB8827820D0 (en) * 1988-11-29 1988-12-29 Janssen Pharmaceutica Nv (1h-azol-1-ylmethyl)substituted quinoline derivatives
CA2002864C (en) * 1988-11-29 1999-11-16 Eddy J. E. Freyne (1h-azol-1-ylmethyl) substituted quinoline, quinazoline or quinoxaline derivatives

Also Published As

Publication number Publication date
DK0666855T3 (da) 1996-10-07
EP0666855A1 (de) 1995-08-16
FI951996A0 (fi) 1995-04-26
CA2146651A1 (en) 1994-05-11
NZ256871A (en) 1995-09-26
ATE143013T1 (de) 1996-10-15
PL175679B1 (pl) 1999-01-29
HU9501207D0 (en) 1995-06-28
DE69304930D1 (de) 1996-10-24
CZ287159B6 (en) 2000-10-11
CZ83795A3 (en) 1995-09-13
US5589484A (en) 1996-12-31
HUT71895A (en) 1996-02-28
NO951588D0 (no) 1995-04-26
AU5178293A (en) 1994-05-24
AU675087B2 (en) 1997-01-23
KR100239003B1 (ko) 2000-02-01
RU95109440A (ru) 1997-03-10
FI951996A (fi) 1995-04-26
WO1994010164A1 (en) 1994-05-11
SK53495A3 (en) 1995-09-13
RU2130933C1 (ru) 1999-05-27
LV10951A (lv) 1995-12-20
GR3021690T3 (en) 1997-02-28
EP0666855B1 (de) 1996-09-18
PL308550A1 (en) 1995-08-21
NO951588L (no) 1995-06-27
ES2094567T3 (es) 1997-01-16
KR950704297A (ko) 1995-11-17
JPH08502503A (ja) 1996-03-19
BG99566A (en) 1996-01-31
DE69304930T2 (de) 1997-02-27

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