LV10923B - Derivates of penciclovir for the treatment of hepatitis- b infections - Google Patents

Derivates of penciclovir for the treatment of hepatitis- b infections Download PDF

Info

Publication number
LV10923B
LV10923B LVP-95-253A LV950253A LV10923B LV 10923 B LV10923 B LV 10923B LV 950253 A LV950253 A LV 950253A LV 10923 B LV10923 B LV 10923B
Authority
LV
Latvia
Prior art keywords
compound
formula
use according
hepatitis
treatment
Prior art date
Application number
LVP-95-253A
Other languages
English (en)
Latvian (lv)
Other versions
LV10923A (lv
Inventor
Malcolm Richard Boyd
David Sutton
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10652653&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LV10923(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of LV10923A publication Critical patent/LV10923A/xx
Publication of LV10923B publication Critical patent/LV10923B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LVP-95-253A 1989-03-03 1995-08-16 Derivates of penciclovir for the treatment of hepatitis- b infections LV10923B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898904855A GB8904855D0 (en) 1989-03-03 1989-03-03 Pharmaceutical treatment

Publications (2)

Publication Number Publication Date
LV10923A LV10923A (lv) 1995-12-20
LV10923B true LV10923B (en) 1996-06-20

Family

ID=10652653

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-95-253A LV10923B (en) 1989-03-03 1995-08-16 Derivates of penciclovir for the treatment of hepatitis- b infections

Country Status (18)

Country Link
US (1) US6136813A (ja)
EP (1) EP0388049B1 (ja)
JP (1) JP2513519B2 (ja)
KR (1) KR0143410B1 (ja)
AT (1) ATE122562T1 (ja)
AU (1) AU628137B2 (ja)
CA (1) CA2011238C (ja)
CY (1) CY1870A (ja)
DE (1) DE69019404T2 (ja)
DK (1) DK0388049T3 (ja)
ES (1) ES2072386T3 (ja)
GB (1) GB8904855D0 (ja)
HK (1) HK116795A (ja)
HU (1) HU205715B (ja)
IE (1) IE67125B1 (ja)
IL (1) IL93594A (ja)
LV (1) LV10923B (ja)
ZA (1) ZA901572B (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9326177D0 (en) * 1993-12-22 1994-02-23 Smithkline Beecham Plc Pharmaceuticals
US6124304A (en) * 1993-10-05 2000-09-26 Smithkline Beecham Plc Penciclovir for the treatment of zoster associated pain
WO1995022330A1 (en) * 1994-02-17 1995-08-24 Commonwealth Scientific And Industrial Research Organisation Antiviral agents
DE69629188T2 (de) * 1995-04-24 2004-04-22 Novartis International Pharmaceutical Ltd. Verwendung von (r)-penciclovirtriphosphat zur herstellung eines arzneimittels zur behandlung von viruserkrankungen
WO1998023285A1 (en) * 1996-11-29 1998-06-04 Smithkline Beecham Plc Use of a combination of penciclovir and alpha-interferon in the manufacture of a medicament for the treatment of hepatitis b
US5939423A (en) * 1997-04-16 1999-08-17 Sciclone Pharmaceuticals, Inc. Treatment of hepatitis B infection with thymosin alpha 1 and famciclovir
AUPO912997A0 (en) * 1997-09-11 1997-10-02 Commonwealth Scientific And Industrial Research Organisation Antiviral agents
US6288033B1 (en) 1998-09-25 2001-09-11 Sciclone Pharmaceuticals, Inc. Treatment of hepatitis B infection with thymosin alpha 1 in combination with lamivudine or in combination with lamivudine and famciclovir
CN1891221A (zh) * 1998-11-02 2007-01-10 三角药物公司 对乙型肝炎病毒的联合治疗
JP2015520144A (ja) 2012-05-11 2015-07-16 アクロン・モレキュールズ・アクチェンゲゼルシャフトＡｋｒｏｎ Ｍｏｌｅｃｕｌｅｓ Ａｇ 疼痛の治療のための化合物の使用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4199574A (en) * 1974-09-02 1980-04-22 Burroughs Wellcome Co. Methods and compositions for treating viral infections and guanine acyclic nucleosides
US4230708A (en) * 1977-10-20 1980-10-28 Stichting Rega V.Z.W. Therapeutic application of (S) -or (RS)-9-(2, 3-dihydroxypropyl) adenine for use as antiviral agents
NL8202626A (nl) * 1982-06-29 1984-01-16 Stichting Rega V Z W Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
US4556659A (en) * 1982-08-09 1985-12-03 Syntex (U.S.A.) Inc. Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-Di-0-substituted propoxymethyl)-purines as antiviral agents
US5059604A (en) * 1982-10-14 1991-10-22 Burroughs Wellcome Co. 2-amino purine derivatives
US4649140A (en) * 1982-10-14 1987-03-10 Burroughs Wellcome Co. Purine derivatives
DE3485225D1 (de) * 1983-08-18 1991-12-05 Beecham Group Plc Antivirale guanin-derivate.
IL73682A (en) * 1983-12-20 1991-08-16 Medivir Ab Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation
DE3582399D1 (de) * 1984-09-20 1991-05-08 Beecham Group Plc Purin-derivate und ihre pharmazeutische verwendung.
SE8406538D0 (sv) * 1984-12-21 1984-12-21 Astra Laekemedel Ab Novel derivatives of purine
DE3671227D1 (de) * 1985-07-27 1990-06-21 Beecham Group Plc 9-substituierte guaninmonohydrate.
SE8602981D0 (sv) * 1986-07-04 1986-07-04 Astra Laekemedel Ab Novel medicinal use
HU196038B (en) * 1987-08-07 1988-09-28 Mta Koezponti Kemiai Kutato In Process for producing antiherpetic pharmaceutics for external use, containing 5-isopropyl-2'-beta-deoxy-uridine
SE8801729D0 (sv) * 1988-05-06 1988-05-06 Astra Ab Purine derivatives for use in therapy
GB8823320D0 (en) * 1988-10-05 1988-11-09 Nycomed As Chemical compounds

Also Published As

Publication number Publication date
LV10923A (lv) 1995-12-20
HUT53522A (en) 1990-11-28
DK0388049T3 (da) 1995-06-06
HU205715B (en) 1992-06-29
CA2011238C (en) 2000-03-28
ES2072386T3 (es) 1995-07-16
EP0388049A3 (en) 1991-11-06
IE67125B1 (en) 1996-03-06
HU901252D0 (en) 1990-05-28
JP2513519B2 (ja) 1996-07-03
AU628137B2 (en) 1992-09-10
DE69019404T2 (de) 1995-10-12
ATE122562T1 (de) 1995-06-15
KR0143410B1 (ko) 1998-07-15
CY1870A (en) 1996-04-05
EP0388049B1 (en) 1995-05-17
KR900014385A (ko) 1990-10-23
JPH02275821A (ja) 1990-11-09
EP0388049A2 (en) 1990-09-19
IL93594A (en) 1995-05-26
US6136813A (en) 2000-10-24
ZA901572B (en) 1991-03-27
CA2011238A1 (en) 1990-09-03
AU5060090A (en) 1990-11-01
DE69019404D1 (de) 1995-06-22
GB8904855D0 (en) 1989-04-12
IE900733L (en) 1990-09-03
IL93594A0 (en) 1990-12-23
HK116795A (en) 1995-07-21

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