LV10267B - Compound with gastric acid inhibitory effect and process for its preparation - Google Patents

Compound with gastric acid inhibitory effect and process for its preparation Download PDF

Info

Publication number
LV10267B
LV10267B LVP-93-691A LV930691A LV10267B LV 10267 B LV10267 B LV 10267B LV 930691 A LV930691 A LV 930691A LV 10267 B LV10267 B LV 10267B
Authority
LV
Latvia
Prior art keywords
compound
benzimidazole
fluoro
point
compound according
Prior art date
Application number
LVP-93-691A
Other languages
English (en)
Latvian (lv)
Other versions
LV10267A (lv
Inventor
Arne Elof Br Ndstrim
Per Lennart Lindberg
Gunnel Elisabeth Sunden
Original Assignee
H Ssle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE19888804629A external-priority patent/SE8804629D0/xx
Priority claimed from SE8902170A external-priority patent/SE8902170D0/xx
Application filed by H Ssle Ab filed Critical H Ssle Ab
Publication of LV10267A publication Critical patent/LV10267A/xx
Publication of LV10267B publication Critical patent/LV10267B/lv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
LVP-93-691A 1988-12-22 1993-06-28 Compound with gastric acid inhibitory effect and process for its preparation LV10267B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE19888804629A SE8804629D0 (sv) 1988-12-22 1988-12-22 New therapeutically active compounds
SE8902170A SE8902170D0 (sv) 1989-06-16 1989-06-16 Therapeutically active compounds
PCT/SE1989/000739 WO1990006924A1 (fr) 1988-12-22 1989-12-20 Compose a effet inhibiteur d'acide gastrique et son procede de preparation

Publications (2)

Publication Number Publication Date
LV10267A LV10267A (lv) 1994-10-20
LV10267B true LV10267B (en) 1995-02-20

Family

ID=26660387

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-93-691A LV10267B (en) 1988-12-22 1993-06-28 Compound with gastric acid inhibitory effect and process for its preparation

Country Status (27)

Country Link
US (1) US5025024A (fr)
EP (1) EP0449935B1 (fr)
JP (1) JP2793905B2 (fr)
KR (1) KR910700248A (fr)
CN (1) CN1028233C (fr)
AT (1) ATE110723T1 (fr)
AU (1) AU639429B2 (fr)
BG (1) BG60101B2 (fr)
CA (1) CA2005980C (fr)
CS (1) CS276361B6 (fr)
DE (1) DE68917937T2 (fr)
DK (1) DK122191A (fr)
EG (1) EG19302A (fr)
FI (1) FI913034A0 (fr)
GR (1) GR1000316B (fr)
HU (1) HUT57204A (fr)
IE (1) IE64199B1 (fr)
IL (1) IL92799A (fr)
LV (1) LV10267B (fr)
MY (1) MY129946A (fr)
NO (1) NO178336C (fr)
NZ (1) NZ231874A (fr)
PH (1) PH27446A (fr)
PL (1) PL160767B1 (fr)
PT (1) PT92649B (fr)
WO (1) WO1990006924A1 (fr)
YU (1) YU47338B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6699885B2 (en) 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US6645988B2 (en) * 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
MXPA04007169A (es) * 2002-01-25 2004-10-29 Santarus Inc Suministro transmucosal de inhibidores de bomba de protones.
CA2517005A1 (fr) * 2003-02-20 2004-09-02 Santarus, Inc. Liberation immediate d'un complexe antacide d'omeprazole presentant une nouvelle formulation pour une elimination rapide et prolongee d'acide gastrique
AR045061A1 (es) * 2003-07-18 2005-10-12 Santarus Inc Formulacion farmaceutica y metodo para tratar trastornos gastrointestinales causados por acido
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
WO2005007115A2 (fr) * 2003-07-18 2005-01-27 Santarus, Inc. Formulations pharmaceutiques utilisees pour inhiber une secretion acide et procede de fabrication associe
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (fr) * 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
IL71664A (en) * 1983-05-03 1987-11-30 Byk Gulden Lomberg Chem Fab Fluoroalkoxy compounds,process for their preparation and pharmaceutical compositions containing the same
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS6150979A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
US4738975A (en) * 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
NZ234564A (en) * 1986-11-21 1991-04-26 Haessle Ab 1-substituted benzimidazoles and pharmaceutical compositions
FI96860C (fi) * 1987-06-17 1996-09-10 Eisai Co Ltd Analogiamenetelmä lääkeaineena käytettävän pyridiinijohdannaisen valmistamiseksi

Also Published As

Publication number Publication date
BG60101B2 (bg) 1993-10-29
PT92649A (pt) 1990-06-29
IL92799A (en) 1994-01-25
DK122191D0 (da) 1991-06-21
HU901095D0 (en) 1991-09-30
NO912414L (no) 1991-08-06
HUT57204A (en) 1991-11-28
DE68917937D1 (de) 1994-10-06
JP2793905B2 (ja) 1998-09-03
AU639429B2 (en) 1993-07-29
PH27446A (en) 1993-07-02
CS276361B6 (en) 1992-05-13
IE64199B1 (en) 1995-07-12
CS734389A3 (en) 1992-01-15
JPH04502460A (ja) 1992-05-07
CA2005980A1 (fr) 1990-06-22
US5025024A (en) 1991-06-18
GR1000316B (el) 1992-06-25
EG19302A (en) 1994-11-30
DK122191A (da) 1991-06-24
EP0449935B1 (fr) 1994-08-31
NO178336B (no) 1995-11-27
CN1043937A (zh) 1990-07-18
CN1028233C (zh) 1995-04-19
KR910700248A (ko) 1991-03-14
PL160767B1 (pl) 1993-04-30
ATE110723T1 (de) 1994-09-15
NO178336C (no) 1996-03-06
FI913034A0 (fi) 1991-06-20
DE68917937T2 (de) 1995-01-05
IE894050L (en) 1990-06-22
MY129946A (en) 2007-05-31
EP0449935A1 (fr) 1991-10-09
IL92799A0 (en) 1990-09-17
YU242789A (en) 1991-04-30
WO1990006924A1 (fr) 1990-06-28
AU4813290A (en) 1990-07-10
NZ231874A (en) 1992-05-26
CA2005980C (fr) 1999-07-13
YU47338B (sh) 1995-01-31
GR890100833A (en) 1991-03-15
LV10267A (lv) 1994-10-20
PT92649B (pt) 1995-09-12
NO912414D0 (no) 1991-06-20

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