LU93036I2 - Vaccin diphtérirque, tétanique, coquelucheux (composant acelluaire, et incluant fimbriae des types 2 et 3), de l'hépatite b (adnr), poliomyélitique (inactivé), et conjugué de l'haemophilus de type b (adsrobé) - Google Patents

Vaccin diphtérirque, tétanique, coquelucheux (composant acelluaire, et incluant fimbriae des types 2 et 3), de l'hépatite b (adnr), poliomyélitique (inactivé), et conjugué de l'haemophilus de type b (adsrobé) Download PDF

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Publication number
LU93036I2
LU93036I2 LU93036C LU93036C LU93036I2 LU 93036 I2 LU93036 I2 LU 93036I2 LU 93036 C LU93036 C LU 93036C LU 93036 C LU93036 C LU 93036C LU 93036 I2 LU93036 I2 LU 93036I2
Authority
LU
Luxembourg
Prior art keywords
vaccine
coquelucheus
adsrobe
adnr
diphtheric
Prior art date
Application number
LU93036C
Other languages
English (en)
French (fr)
Original Assignee
Sanofi Pasteur Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/433,646 external-priority patent/US5877298A/en
Application filed by Sanofi Pasteur Ltd filed Critical Sanofi Pasteur Ltd
Publication of LU93036I2 publication Critical patent/LU93036I2/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/099Bordetella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55544Bacterial toxins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
LU93036C 1995-05-04 2016-04-21 Vaccin diphtérirque, tétanique, coquelucheux (composant acelluaire, et incluant fimbriae des types 2 et 3), de l'hépatite b (adnr), poliomyélitique (inactivé), et conjugué de l'haemophilus de type b (adsrobé) LU93036I2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/433,646 US5877298A (en) 1995-05-04 1995-05-04 Acellular pertussis vaccines and methods of preparing thereof
US50174395A 1995-07-12 1995-07-12
PCT/CA1996/000279 WO1996034883A1 (en) 1995-05-04 1996-05-02 Acellular pertussis vaccines and methods of preparation thereof

Publications (1)

Publication Number Publication Date
LU93036I2 true LU93036I2 (fr) 2016-06-21

Family

ID=27029924

Family Applications (1)

Application Number Title Priority Date Filing Date
LU93036C LU93036I2 (fr) 1995-05-04 2016-04-21 Vaccin diphtérirque, tétanique, coquelucheux (composant acelluaire, et incluant fimbriae des types 2 et 3), de l'hépatite b (adnr), poliomyélitique (inactivé), et conjugué de l'haemophilus de type b (adsrobé)

Country Status (18)

Country Link
US (1) US6399076B2 (de)
EP (7) EP1234580A1 (de)
CN (2) CN100387618C (de)
AT (3) ATE496634T1 (de)
AU (2) AU710538B2 (de)
BR (2) BR9608114A (de)
CA (3) CA2433502A1 (de)
DE (3) DE69638326D1 (de)
DK (3) DK0824358T3 (de)
ES (2) ES2180758T3 (de)
FR (1) FR16C0015I2 (de)
HK (1) HK1016191A1 (de)
LU (1) LU93036I2 (de)
MX (1) MX9708481A (de)
NL (1) NL300804I2 (de)
NZ (2) NZ306391A (de)
PT (3) PT1393744E (de)
WO (2) WO1996034883A1 (de)

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DE69511392T2 (de) * 1994-04-28 2000-03-23 Takeda Chemical Industries, Ltd. Verfahren zur trennung von protektiven verbindungen aus bordetella pertussis
US6696065B1 (en) * 1995-05-04 2004-02-24 Aventis Pastuer Limited Acellular pertussis vaccines and methods of preparation thereof
GB9611501D0 (en) * 1996-06-03 1996-08-07 Smithkline Beecham Biolog Vaccine compositions
RU2194531C2 (ru) * 1996-07-02 2002-12-20 Коннот Лабораториз Лимитед Поливалентные ассоциированные коклюшно-дифтерийно-столбнячно (акдс)-полиомиелитные вакцины
JP4530317B2 (ja) * 1998-10-21 2010-08-25 学校法人北里研究所 減毒化トキシンを含むワクチン製剤
KR101337320B1 (ko) * 2003-11-20 2013-12-06 사노피 파스퇴르 인크 백일해 독소의 정제방법 및 이에 유용한 펩타이드
EP1828378B1 (de) * 2004-12-17 2014-06-11 De Staat der Nederlanden, vert. door de minister Van VWS, Ministerie van Volksgezondheid, Welzijn en Sport Deacylierung von lps in gram negativen bakterien
ES2423663T3 (es) 2005-08-08 2013-09-23 Oregon Health And Science University Inactivación de patógenos con peróxido de hidrógeno para la producción de vacunas
EP1867638A1 (de) * 2006-06-16 2007-12-19 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Verfahren zur kovalenten Verknüpfung zweier Moleküle mittels Diels-Alder-Reaktion mit inversem Elektronenbedarf
MX2009002560A (es) 2006-09-07 2009-03-20 Glaxosmithkline Biolog Sa Vacuna.
CN100537767C (zh) * 2007-04-29 2009-09-09 中国药品生物制品检定所 百日咳疫苗保护性抗原的重组表达及其应用
GB0822633D0 (en) * 2008-12-11 2009-01-21 Novartis Ag Formulation
US20100330158A1 (en) * 2009-03-31 2010-12-30 Innopharma, Llc Protein-assisted drug delivery system for the targeted administration of active agents
EP2430040A1 (de) 2009-05-11 2012-03-21 Novartis AG Antigenaufreinigungs­verfahren für pertactinantigen
WO2013043608A1 (en) * 2011-09-20 2013-03-28 Bio-Rad Laboratories, Inc. Removal of virucidal agents from biomolecule preparations
WO2013049535A2 (en) 2011-09-30 2013-04-04 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Influenza vaccine
CN102584958A (zh) * 2012-02-08 2012-07-18 北京天坛生物制品股份有限公司 百日咳杆菌69kd外膜蛋白的纯化方法
CN102793915B (zh) * 2012-07-25 2013-10-23 天津康希诺生物技术有限公司 一种无细胞百日咳疫苗的生产方法
US8916173B2 (en) 2013-03-08 2014-12-23 Crucell Holland B.V. Acellular pertussis vaccine
EP3302784B1 (de) 2015-06-05 2021-10-06 W.R. Grace & Co.-Conn. Adsorbierende klärmittel für bioprozesstechnik und verfahren zur herstellung und verwendung davon
CN105106947A (zh) * 2015-07-21 2015-12-02 华兰生物工程股份有限公司 过氧化氢脱毒的无细胞百日咳疫苗及其制备方法
EP3518968B1 (de) 2016-10-03 2022-01-05 The U.S.A. as represented by the Secretary, Department of Health and Human Services Hiv-1-env-fusionspeptid-immunogene und deren verwendung
WO2018081832A1 (en) 2016-10-31 2018-05-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Peptide fragments from filoviruses and their uses
US11235056B2 (en) 2017-03-24 2022-02-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Glycan-masked engineered outer domains of HIV-1 gp120 and their use
KR102426041B1 (ko) * 2017-08-01 2022-07-29 주식회사 녹십자 냉동 및 해동 과정을 포함하는 백일해균 유래 단백질 수득 방법
WO2019079337A1 (en) 2017-10-16 2019-04-25 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services RECOMBINANT HIV-1 ENVELOPE PROTEINS AND THEIR USE
WO2020061564A1 (en) 2018-09-23 2020-03-26 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Hiv-1 env fusion peptide nanoparticle carrier conjugates and their use
AU2019368218A1 (en) 2018-10-22 2021-05-27 New York University Recombinant GP120 protein with V1-loop deletion
CN110358802B (zh) * 2019-08-16 2021-06-18 长春百克生物科技股份公司 一种去除百日咳组分菌毛蛋白2/3内毒素的方法
CN112094354B (zh) * 2020-11-05 2021-02-02 苏州世诺生物技术有限公司 副鸡禽杆菌基因工程亚单位疫苗、其制备方法及应用
EP4380613A1 (de) 2021-08-03 2024-06-12 The United States of America, as represented by the Secretary, Department of Health and Human Services Hiv-1 impfung und samt-247 microbizid zur vorbeugung von hiv-1 infektion
WO2023192835A1 (en) 2022-03-27 2023-10-05 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Base-covered hiv-1 envelope ectodomains and their use
CN117417419B (zh) * 2023-01-10 2024-04-19 康希诺生物股份公司 一种百日咳毒素脱毒方法及无细胞百白破联合疫苗

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US4258029A (en) 1979-04-23 1981-03-24 Connaught Laboratories Limited Synthetic adjuvants for stimulation of antigenic responses
DE3521994A1 (de) 1985-06-20 1987-01-02 Bayer Ag N-(2-aminoacylamido-2-desoxy-hexosyl)-amide-, -carbamate und -harnstoffe, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
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US5101014A (en) 1989-02-10 1992-03-31 United States Of America Process for the purification of a 69,000 da outer membrane protein of Bordetella pertussis
AU5432690A (en) * 1989-03-31 1990-11-05 Washington University Bordetella vaccines
US5276142A (en) 1989-12-11 1994-01-04 American Cyanamid Company Process for purification of a 69000 dalton antigenic protein from Bordetella pertussis
GB9007657D0 (en) * 1990-04-04 1990-05-30 Connaught Lab Purification of a pertussis outer membrane protein(omp69)
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US5877298A (en) * 1995-05-04 1999-03-02 Connaught Lab Acellular pertussis vaccines and methods of preparing thereof

Also Published As

Publication number Publication date
BR9608115A (pt) 2004-07-13
DE69622555D1 (de) 2002-08-29
ATE496634T1 (de) 2011-02-15
CN1198099A (zh) 1998-11-04
DE69638326D1 (de) 2011-03-10
CA2220063C (en) 2003-08-26
AU710538B2 (en) 1999-09-23
US20010009666A1 (en) 2001-07-26
DE69622555T2 (de) 2003-03-27
FR16C0015I1 (de) 2016-06-10
HK1016191A1 (en) 1999-10-29
AU5494196A (en) 1996-11-21
EP0824358B1 (de) 2002-12-04
CN100387618C (zh) 2008-05-14
EP0826001A1 (de) 1998-03-04
FR16C0015I2 (fr) 2017-06-09
DE69625191D1 (de) 2003-01-16
WO1996034623A1 (en) 1996-11-07
ATE228851T1 (de) 2002-12-15
AU715417B2 (en) 2000-02-03
NL300804I2 (de) 2016-11-01
PT826001E (pt) 2002-12-31
CA2220048A1 (en) 1996-11-07
CA2433502A1 (en) 1996-11-07
PT1393744E (pt) 2011-05-03
CA2220048C (en) 2006-03-07
AU5494096A (en) 1996-11-21
MX9708481A (es) 1998-02-28
BR9608114A (pt) 2000-10-31
ES2180758T3 (es) 2003-02-16
EP1234579A1 (de) 2002-08-28
CA2220063A1 (en) 1996-11-07
WO1996034883A1 (en) 1996-11-07
PT824358E (pt) 2003-02-28
US6399076B2 (en) 2002-06-04
NZ306392A (en) 1999-04-29
EP1405643A1 (de) 2004-04-07
EP1233022B1 (de) 2015-12-09
DE69625191T2 (de) 2003-07-10
NZ306391A (en) 1999-03-29
DK0824358T3 (da) 2003-01-27
EP1393744A1 (de) 2004-03-03
DK1393744T3 (da) 2011-05-30
EP1234580A1 (de) 2002-08-28
ES2182971T3 (es) 2003-03-16
EP1233022A1 (de) 2002-08-21
EP1393744B1 (de) 2011-01-26
EP0826001B1 (de) 2002-07-24
DK0826001T3 (da) 2002-11-18
CN1193324A (zh) 1998-09-16
ATE221081T1 (de) 2002-08-15
EP0824358A1 (de) 1998-02-25

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