LU83293A1 - Amines antihypertensives,leur procede de preparation et compositions antihypertensives en contenant - Google Patents

Amines antihypertensives,leur procede de preparation et compositions antihypertensives en contenant Download PDF

Info

Publication number
LU83293A1
LU83293A1 LU83293A LU83293A LU83293A1 LU 83293 A1 LU83293 A1 LU 83293A1 LU 83293 A LU83293 A LU 83293A LU 83293 A LU83293 A LU 83293A LU 83293 A1 LU83293 A1 LU 83293A1
Authority
LU
Luxembourg
Prior art keywords
group
alkyl
compound according
formula
compounds
Prior art date
Application number
LU83293A
Other languages
English (en)
French (fr)
Inventor
B Loev
J Shroff
Original Assignee
Usv Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Usv Pharma Corp filed Critical Usv Pharma Corp
Publication of LU83293A1 publication Critical patent/LU83293A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
LU83293A 1980-04-11 1981-04-10 Amines antihypertensives,leur procede de preparation et compositions antihypertensives en contenant LU83293A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13936780 1980-04-11
US06/139,367 US4258042A (en) 1980-04-11 1980-04-11 Antihypertensive pyridines and compositions

Publications (1)

Publication Number Publication Date
LU83293A1 true LU83293A1 (fr) 1981-12-02

Family

ID=22486280

Family Applications (1)

Application Number Title Priority Date Filing Date
LU83293A LU83293A1 (fr) 1980-04-11 1981-04-10 Amines antihypertensives,leur procede de preparation et compositions antihypertensives en contenant

Country Status (23)

Country Link
US (1) US4258042A (de)
JP (1) JPS56158762A (de)
AR (2) AR227306A1 (de)
AU (1) AU6941181A (de)
BE (1) BE888327A (de)
CA (1) CA1175825A (de)
CH (1) CH647519A5 (de)
DE (1) DE3109794A1 (de)
DK (1) DK162581A (de)
ES (1) ES8202001A1 (de)
FI (1) FI810981L (de)
FR (1) FR2480284A1 (de)
GB (1) GB2073739B (de)
IL (1) IL62362A (de)
IT (1) IT1137539B (de)
LU (1) LU83293A1 (de)
NL (1) NL8100745A (de)
NO (1) NO811240L (de)
NZ (1) NZ196787A (de)
PH (1) PH15278A (de)
SE (1) SE8101211L (de)
ZA (1) ZA81802B (de)
ZW (1) ZW8281A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3208628A1 (de) * 1982-03-10 1983-09-22 Bayer Ag, 5090 Leverkusen Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US4656181A (en) * 1982-11-24 1987-04-07 Cermol S.A. Esters of 1,4-dihydropyridines, processes for the preparation of the new esters, and medicaments containing the same
US4491582A (en) * 1983-03-03 1985-01-01 Usv Pharmaceutical Corporation N-(substituted piperazino)-1,4-dihydropyridine-3,5-carboxylic acid
US4435395A (en) 1983-03-03 1984-03-06 Usv Pharmaceutical Corporation N-Substituted 1,4-dihydropyridazines and pharmaceutical compositions
US4500528A (en) * 1983-03-03 1985-02-19 Usv Pharmaceutical Corporation N-Substituted 1,4-dihydropyridines and pharmaceutical compositions
US4503223A (en) * 1983-08-11 1985-03-05 Usv Pharmaceutical Corporation Process for the purification of N-morpholinoalkyl dihydropyridines
IE57810B1 (en) * 1984-03-27 1993-04-21 Delagrange Lab 1,4-dihydropyridine derivatives,their preparation and their use
US4757071A (en) * 1984-12-14 1988-07-12 Nisshin Flour Milling Co., Ltd. 1,4-dihydropyridine derivatives, and pharmaceutical compositions containing same, useful for treating cardiovascular diseases
US4833150A (en) * 1985-03-14 1989-05-23 Nelson Research & Development Co. 1,4-dihydropyridines
US4659717A (en) * 1985-08-21 1987-04-21 Eli Lilly And Company Dihydropyridines useful in the treatment of angina and stroke
DE3544211A1 (de) * 1985-12-13 1987-06-19 Bayer Ag Neue, fluorhaltige 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US4780538A (en) * 1986-02-12 1988-10-25 Merck & Co., Inc. Process for 1,4-dihydropyridine compounds using a titanamine catalyst
US4849436A (en) * 1986-03-11 1989-07-18 Nelson Research & Development Co. 1,4-dihydropyridines

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5170767A (en) * 1974-12-17 1976-06-18 Yamanouchi Pharma Co Ltd Shinki nn chikan 1*44 jihidoropirijinjudotaino goseiho

Also Published As

Publication number Publication date
CH647519A5 (de) 1985-01-31
AR229435A1 (es) 1983-08-15
CA1175825A (en) 1984-10-09
GB2073739B (en) 1984-07-11
ES499667A0 (es) 1982-02-01
AU6941181A (en) 1981-10-15
US4258042A (en) 1981-03-24
IT8121078A0 (it) 1981-04-10
PH15278A (en) 1982-11-02
AR227306A1 (es) 1982-10-15
ES8202001A1 (es) 1982-02-01
IL62362A0 (en) 1981-05-20
FR2480284A1 (fr) 1981-10-16
DK162581A (da) 1981-10-12
BE888327A (fr) 1981-10-08
ZW8281A1 (en) 1981-07-01
JPS56158762A (en) 1981-12-07
FI810981L (fi) 1981-10-12
GB2073739A (en) 1981-10-21
NL8100745A (nl) 1981-11-02
SE8101211L (sv) 1981-10-12
ZA81802B (en) 1982-02-24
FR2480284B1 (de) 1984-01-06
DE3109794A1 (de) 1982-01-28
NO811240L (no) 1981-10-12
NZ196787A (en) 1984-04-27
IL62362A (en) 1984-12-31
IT1137539B (it) 1986-09-10

Similar Documents

Publication Publication Date Title
EP0635003B1 (de) Perhydroisoindole derivate als substanz p antagonisten
CH639653A5 (fr) Aminothiazoles et composition pharmaceutique les contenant.
LU83293A1 (fr) Amines antihypertensives,leur procede de preparation et compositions antihypertensives en contenant
EP0003199A2 (de) Tetrahydropyridinylindolderivate und ihre Salze, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel, und diese enthaltende pharmazeutische Zusammensetzungen
EP0005689B1 (de) Lactam-N-Essigsäuren und ihre Amide, Verfahren zu ihrer Herstellung und Heilmittel, die sie enthalten
EP0382634A1 (de) Pyridazin-Derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammenstellungen
EP0138721B1 (de) Benzensulfonyllactame, Verfahren zu ihrer Herstellung und ihre Anwendung als wirksame Bestandteile in pharmazeutischen Zusammensetzungen
FR2495153A1 (fr) Nouvelles dibenzazepines, leur preparation et leur application comme medicaments
FR2533564A1 (fr) Derives de la piperazine presentant une activite anticholinergique et/ou antihistaminique
CH649920A5 (fr) Derives substitues de l'acide 4-phenyl 4-oxo 2-butenoique, a titre de medicaments.
BE1000694A3 (fr) Nouveaux derives oxy-5 du tetrahydrofurane, un procede pour leur preparation et compositions therapeutiques en contenant.
EP0022705B1 (de) Tetrahydropyridinyl-indol-Derivate und ihre Salze, ihre Herstellung, ihre Anwendung als Arzneimittel und sie enthaltende Zusammensetzungen
FR2480286A1 (fr) Nouveaux derives de theophyllinylmethyldioxolane, leurs procedes de preparation et leur application en therapeutique
EP0259206B1 (de) 1,4-Dihydropyridinderivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
CH659469A5 (fr) Derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2, leur preparation et les medicaments et compositions les renfermant.
WO1990003972A1 (fr) Derives de methyl-4 ((phenyl-4 piperazinyl-1)-2 ethyl)-5 thiazole
EP0929550A1 (de) N-(benzothiazol-2-yl)piperidine-1-ethanamine derivate, ihre herstellung und therapeutische verwendung
CH635570A5 (fr) Derives d'amino-alcools.
JPS62281860A (ja) アルキレンアミノアルキレン　ヘテロ原子基を有するジヒドロ−３，５−ジカルボキシレ−ト
FR2547822A1 (fr) Acylpiperazinoquinazolines substituees utiles comme medicaments et procede pour leur preparation
EP0294258A1 (de) Hydrazin-Derivate, Verfahren zu deren Erhaltung und diese enthaltende pharmazeutische Zusammensetzungen
EP0362006A1 (de) Chinolinderivate, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
EP0100257B1 (de) Aminoalkylnaphthalen-Derivate, ihre Salze und Verfahren zu ihrer Herstellung und die Verwendung dieser Derivate und Salze in der Therapeutik
CA1076117A (fr) Procede d'obtention de nouveaux ethers aryliques et les produits en resultant
FR2516510A1 (fr) Derives de la (trimethoxy-3,4,5-cinnamoyl)-1-aminocarbonylethyl-4-piperazine substituee utilisables en pharmacie et procede pour leur preparation