IL62362A - Diethyl-1,4-dihydro-4-(2-trifluoromethylphenyl)-2,6-dimethyl-1-(2-morpholinoethyl)-3,5-pyridinedicarboxylate,its preparation and anti-hypertensive compositions comprising them - Google Patents

Diethyl-1,4-dihydro-4-(2-trifluoromethylphenyl)-2,6-dimethyl-1-(2-morpholinoethyl)-3,5-pyridinedicarboxylate,its preparation and anti-hypertensive compositions comprising them

Info

Publication number
IL62362A
IL62362A IL62362A IL6236281A IL62362A IL 62362 A IL62362 A IL 62362A IL 62362 A IL62362 A IL 62362A IL 6236281 A IL6236281 A IL 6236281A IL 62362 A IL62362 A IL 62362A
Authority
IL
Israel
Prior art keywords
pyridinedicarboxylate
morpholinoethyl
trifluoromethylphenyl
dihydro
diethyl
Prior art date
Application number
IL62362A
Other languages
English (en)
Other versions
IL62362A0 (en
Original Assignee
Usv Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Usv Pharma Corp filed Critical Usv Pharma Corp
Publication of IL62362A0 publication Critical patent/IL62362A0/xx
Publication of IL62362A publication Critical patent/IL62362A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
IL62362A 1980-04-11 1981-03-13 Diethyl-1,4-dihydro-4-(2-trifluoromethylphenyl)-2,6-dimethyl-1-(2-morpholinoethyl)-3,5-pyridinedicarboxylate,its preparation and anti-hypertensive compositions comprising them IL62362A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/139,367 US4258042A (en) 1980-04-11 1980-04-11 Antihypertensive pyridines and compositions

Publications (2)

Publication Number Publication Date
IL62362A0 IL62362A0 (en) 1981-05-20
IL62362A true IL62362A (en) 1984-12-31

Family

ID=22486280

Family Applications (1)

Application Number Title Priority Date Filing Date
IL62362A IL62362A (en) 1980-04-11 1981-03-13 Diethyl-1,4-dihydro-4-(2-trifluoromethylphenyl)-2,6-dimethyl-1-(2-morpholinoethyl)-3,5-pyridinedicarboxylate,its preparation and anti-hypertensive compositions comprising them

Country Status (23)

Country Link
US (1) US4258042A (xx)
JP (1) JPS56158762A (xx)
AR (2) AR227306A1 (xx)
AU (1) AU6941181A (xx)
BE (1) BE888327A (xx)
CA (1) CA1175825A (xx)
CH (1) CH647519A5 (xx)
DE (1) DE3109794A1 (xx)
DK (1) DK162581A (xx)
ES (1) ES8202001A1 (xx)
FI (1) FI810981L (xx)
FR (1) FR2480284A1 (xx)
GB (1) GB2073739B (xx)
IL (1) IL62362A (xx)
IT (1) IT1137539B (xx)
LU (1) LU83293A1 (xx)
NL (1) NL8100745A (xx)
NO (1) NO811240L (xx)
NZ (1) NZ196787A (xx)
PH (1) PH15278A (xx)
SE (1) SE8101211L (xx)
ZA (1) ZA81802B (xx)
ZW (1) ZW8281A1 (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3208628A1 (de) * 1982-03-10 1983-09-22 Bayer Ag, 5090 Leverkusen Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US4656181A (en) * 1982-11-24 1987-04-07 Cermol S.A. Esters of 1,4-dihydropyridines, processes for the preparation of the new esters, and medicaments containing the same
US4491582A (en) * 1983-03-03 1985-01-01 Usv Pharmaceutical Corporation N-(substituted piperazino)-1,4-dihydropyridine-3,5-carboxylic acid
US4500528A (en) * 1983-03-03 1985-02-19 Usv Pharmaceutical Corporation N-Substituted 1,4-dihydropyridines and pharmaceutical compositions
US4435395A (en) 1983-03-03 1984-03-06 Usv Pharmaceutical Corporation N-Substituted 1,4-dihydropyridazines and pharmaceutical compositions
US4503223A (en) * 1983-08-11 1985-03-05 Usv Pharmaceutical Corporation Process for the purification of N-morpholinoalkyl dihydropyridines
IE57810B1 (en) * 1984-03-27 1993-04-21 Delagrange Lab 1,4-dihydropyridine derivatives,their preparation and their use
US4757071A (en) * 1984-12-14 1988-07-12 Nisshin Flour Milling Co., Ltd. 1,4-dihydropyridine derivatives, and pharmaceutical compositions containing same, useful for treating cardiovascular diseases
US4833150A (en) * 1985-03-14 1989-05-23 Nelson Research & Development Co. 1,4-dihydropyridines
US4659717A (en) * 1985-08-21 1987-04-21 Eli Lilly And Company Dihydropyridines useful in the treatment of angina and stroke
DE3544211A1 (de) * 1985-12-13 1987-06-19 Bayer Ag Neue, fluorhaltige 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US4780538A (en) * 1986-02-12 1988-10-25 Merck & Co., Inc. Process for 1,4-dihydropyridine compounds using a titanamine catalyst
US4849436A (en) * 1986-03-11 1989-07-18 Nelson Research & Development Co. 1,4-dihydropyridines

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5170767A (en) * 1974-12-17 1976-06-18 Yamanouchi Pharma Co Ltd Shinki nn chikan 1*44 jihidoropirijinjudotaino goseiho

Also Published As

Publication number Publication date
US4258042A (en) 1981-03-24
LU83293A1 (fr) 1981-12-02
DE3109794A1 (de) 1982-01-28
AU6941181A (en) 1981-10-15
NO811240L (no) 1981-10-12
AR229435A1 (es) 1983-08-15
ZA81802B (en) 1982-02-24
GB2073739A (en) 1981-10-21
FR2480284A1 (fr) 1981-10-16
ES499667A0 (es) 1982-02-01
SE8101211L (sv) 1981-10-12
CH647519A5 (de) 1985-01-31
PH15278A (en) 1982-11-02
NL8100745A (nl) 1981-11-02
ES8202001A1 (es) 1982-02-01
NZ196787A (en) 1984-04-27
IT1137539B (it) 1986-09-10
DK162581A (da) 1981-10-12
FI810981L (fi) 1981-10-12
FR2480284B1 (xx) 1984-01-06
GB2073739B (en) 1984-07-11
ZW8281A1 (en) 1981-07-01
BE888327A (fr) 1981-10-08
JPS56158762A (en) 1981-12-07
IT8121078A0 (it) 1981-04-10
CA1175825A (en) 1984-10-09
AR227306A1 (es) 1982-10-15
IL62362A0 (en) 1981-05-20

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