LT4381B - N-monopakeistų ir n, n'-dipakeistų nesimetrinių ciklinių karbamidų gavimo būdas - Google Patents

N-monopakeistų ir n, n'-dipakeistų nesimetrinių ciklinių karbamidų gavimo būdas Download PDF

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Publication number
LT4381B
LT4381B LT97-188A LT97188A LT4381B LT 4381 B LT4381 B LT 4381B LT 97188 A LT97188 A LT 97188A LT 4381 B LT4381 B LT 4381B
Authority
LT
Lithuania
Prior art keywords
substituted
alkyl
benzyl
group
independently selected
Prior art date
Application number
LT97-188A
Other languages
English (en)
Lithuanian (lt)
Other versions
LT97188A (en
Inventor
James David Rodgers
Jung-Hui Sun
Original Assignee
Dupont Pharmaceuticals Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dupont Pharmaceuticals Company filed Critical Dupont Pharmaceuticals Company
Publication of LT97188A publication Critical patent/LT97188A/xx
Publication of LT4381B publication Critical patent/LT4381B/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/04—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Enzymes And Modification Thereof (AREA)
LT97-188A 1995-06-07 1997-12-03 N-monopakeistų ir n, n'-dipakeistų nesimetrinių ciklinių karbamidų gavimo būdas LT4381B (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/481,683 US5532357A (en) 1995-06-07 1995-06-07 Method for preparing N-monosubstituted and N,N'-disubstituted unsymmetrical cyclic ureas

Publications (2)

Publication Number Publication Date
LT97188A LT97188A (en) 1998-04-27
LT4381B true LT4381B (lt) 1998-09-25

Family

ID=23912954

Family Applications (1)

Application Number Title Priority Date Filing Date
LT97-188A LT4381B (lt) 1995-06-07 1997-12-03 N-monopakeistų ir n, n'-dipakeistų nesimetrinių ciklinių karbamidų gavimo būdas

Country Status (26)

Country Link
US (1) US5532357A (xx)
EP (2) EP1029859A1 (xx)
JP (1) JPH11506779A (xx)
KR (1) KR19990022467A (xx)
CN (1) CN1192209A (xx)
AR (1) AR002384A1 (xx)
AU (1) AU704535B2 (xx)
BR (1) BR9609493A (xx)
CA (1) CA2223391A1 (xx)
CZ (1) CZ381997A3 (xx)
EA (1) EA000363B1 (xx)
EE (1) EE9700330A (xx)
HR (1) HRP960259A2 (xx)
HU (1) HUP9900913A2 (xx)
IL (1) IL122424A0 (xx)
LT (1) LT4381B (xx)
LV (1) LV12045B (xx)
MX (1) MX9709652A (xx)
NO (1) NO975679L (xx)
NZ (1) NZ309648A (xx)
PL (1) PL323993A1 (xx)
SI (1) SI9620077A (xx)
SK (1) SK164397A3 (xx)
TW (1) TW358091B (xx)
WO (1) WO1996040652A1 (xx)
ZA (1) ZA964847B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5466797A (en) * 1994-06-30 1995-11-14 The Du Pont Merck Pharmaceutical Company Intermediates for the preparation of cyclic urea
US6054597A (en) * 1995-11-14 2000-04-25 Dupont Pharmaceuticals Processes and intermediates for the preparation of cyclic urea HIV protease inhibitors
US6218386B1 (en) 1996-11-08 2001-04-17 Dupont Pharmaceuticals A1-(3-aminoindazol-5-yl)-3 butyl-cyclic urea useful as a HIV protease inhibitor
US5932570A (en) * 1996-11-08 1999-08-03 Dupont Pharmaceuticals Company 1-(3-aminoindazol-5-yl)-3-phenylmethyl-cyclic ureas useful as HIV protease inhibitors
WO1998020008A1 (en) * 1996-11-08 1998-05-14 Du Pont Pharmaceuticals Company 1-(3-aminoindazol-5-yl)-3-phenylmethyl-cyclic ureas useful as hiv protease inhibitors
AU6870098A (en) * 1997-03-31 1998-10-22 Du Pont Merck Pharmaceutical Company, The Indazoles of cyclic ureas useful as hiv protease inhibitors
US6218534B1 (en) 1997-10-06 2001-04-17 Dupont Pharmaceuticals Company Preparation of asymmetric cyclic ureas through a monoacylated diamine intermediate
EP1091944A1 (en) * 1998-06-30 2001-04-18 Du Pont Pharmaceuticals Company 1,3-benzodiazepin-2-ones and 1,3-benzoxazepin-2-ones useful as hiv reverse transcriptase inhibitors
CA2370141A1 (en) 1999-05-26 2000-12-07 James D. Rodgers 1,4-benzodiazepin-2-ones useful as hiv reverse transcriptase inhibitors
US6313110B1 (en) * 1999-06-02 2001-11-06 Dupont Pharmaceuticals Company Substituted 2H-1,3-diazapin-2-one useful as an HIV protease inhibitor
FR2810039B1 (fr) * 2000-06-13 2007-05-25 Centre Nat Rech Scient Composes urees cycliques et leur procede de preparation
AU2002258633A1 (en) * 2001-03-28 2002-10-15 Bristol-Myers Squibb Company Cyanamide, alkoxyamino, and urea derivatives of 1,3-benzodiazapines as hiv reverse transcriptase inhibitors
US20080033167A1 (en) * 2005-12-29 2008-02-07 Gilles Guichard Compositions and methods for synthesizing heterocyclic therapeutic compounds

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8197630B2 (en) 2003-11-26 2012-06-12 Glopak Inc. Laser welding system for sealing or cutting polymeric sheets
US8230562B2 (en) 2005-04-06 2012-07-31 Avago Technologies Wireless Ip (Singapore) Pte. Ltd. Method of fabricating an acoustic resonator comprising a filled recessed region

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5610294A (en) * 1991-10-11 1997-03-11 The Du Pont Merck Pharmaceutical Company Substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors
ATE216371T1 (de) * 1991-10-11 2002-05-15 Du Pont Pharm Co Cyclische harnstoffe und analoga verwendbar als retrovirale proteasehemmer
US5430043A (en) * 1993-08-24 1995-07-04 G. D. Searle & Co. Platelet aggregation inhibitors
US5466797A (en) * 1994-06-30 1995-11-14 The Du Pont Merck Pharmaceutical Company Intermediates for the preparation of cyclic urea
US5530124A (en) * 1994-06-30 1996-06-25 The Dupont Merck Pharmaceutical Company Method for preparing cyclic ureas and their use for the synthesis of HIV protease inhibitors
US5532356A (en) * 1995-06-06 1996-07-02 The Dupont Merck Pharmaceutical Company Method for preparing N,N'-disubstituted cyclic ureas

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8197630B2 (en) 2003-11-26 2012-06-12 Glopak Inc. Laser welding system for sealing or cutting polymeric sheets
US8230562B2 (en) 2005-04-06 2012-07-31 Avago Technologies Wireless Ip (Singapore) Pte. Ltd. Method of fabricating an acoustic resonator comprising a filled recessed region

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HAROLD KOHN ET AL.: "Syntheses and spectral properties of substituted imidazolidones and imidazolines", J. ORG. CHEM., 1977, pages 941 - 948
MICHAEL A. EISSENSTAT, JOHN D. WEAVER III: "A retro-Diels-Alder approach to oxazoles and imidazoles", J. ORG. CHEM., 1993, pages 3387 - 3390

Also Published As

Publication number Publication date
TW358091B (en) 1999-05-11
HUP9900913A2 (hu) 1999-09-28
EA000363B1 (ru) 1999-06-24
BR9609493A (pt) 1999-03-02
NZ309648A (en) 1998-09-24
HRP960259A2 (en) 1997-10-31
EE9700330A (et) 1998-06-15
EA199800034A1 (ru) 1998-08-27
LV12045B (en) 1998-09-20
PL323993A1 (en) 1998-04-27
AU5986896A (en) 1996-12-30
SK164397A3 (en) 2000-04-10
NO975679L (no) 1998-02-02
ZA964847B (en) 1997-12-08
JPH11506779A (ja) 1999-06-15
EP1029859A1 (en) 2000-08-23
IL122424A0 (en) 1998-06-15
SI9620077A (sl) 1998-08-31
LT97188A (en) 1998-04-27
US5532357A (en) 1996-07-02
EP0837855A4 (en) 1998-09-02
AU704535B2 (en) 1999-04-29
CA2223391A1 (en) 1996-12-19
KR19990022467A (ko) 1999-03-25
CN1192209A (zh) 1998-09-02
CZ381997A3 (cs) 1999-01-13
LV12045A (lv) 1998-05-20
MX9709652A (es) 1998-03-29
AR002384A1 (es) 1998-03-11
NO975679D0 (no) 1997-12-05
EP0837855A1 (en) 1998-04-29
WO1996040652A1 (en) 1996-12-19

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Legal Events

Date Code Title Description
PD9A Change of patent owner

Free format text: DUPONT PHARMACEUTICALS COMPANY,CHESTNUT RUN PLAZA, 974 CENTRE ROAD, WILMINGTON, DELAWARE 19805,US,19990306,

MM9A Lapsed patents

Effective date: 20010606