LT3868B - Process for the preparation of peptide, use them and process for the preparation of pharmaceutical composition - Google Patents

Process for the preparation of peptide, use them and process for the preparation of pharmaceutical composition Download PDF

Info

Publication number
LT3868B
LT3868B LTIP1466A LTIP1466A LT3868B LT 3868 B LT3868 B LT 3868B LT IP1466 A LTIP1466 A LT IP1466A LT IP1466 A LTIP1466 A LT IP1466A LT 3868 B LT3868 B LT 3868B
Authority
LT
Lithuania
Prior art keywords
substituted
group
aryl
formula
peptide
Prior art date
Application number
LTIP1466A
Other languages
English (en)
Lithuanian (lt)
Inventor
Stephan Henke
Gerhard Breipohl
Jochen Knolle
Bernward Schoelkens
Hermann Gerhards
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of LTIP1466A publication Critical patent/LTIP1466A/xx
Publication of LT3868B publication Critical patent/LT3868B/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/18—Kallidins; Bradykinins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
LTIP1466A 1989-08-14 1993-11-12 Process for the preparation of peptide, use them and process for the preparation of pharmaceutical composition LT3868B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3926822A DE3926822A1 (de) 1989-08-14 1989-08-14 Peptide mit bradykinin-antagonistischer wirkung

Publications (2)

Publication Number Publication Date
LTIP1466A LTIP1466A (en) 1995-06-26
LT3868B true LT3868B (en) 1996-04-25

Family

ID=6387091

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP1466A LT3868B (en) 1989-08-14 1993-11-12 Process for the preparation of peptide, use them and process for the preparation of pharmaceutical composition

Country Status (24)

Country Link
EP (1) EP0413277B1 (fi)
JP (1) JP2997519B2 (fi)
KR (1) KR0173976B1 (fi)
CN (1) CN1034577C (fi)
AT (1) ATE114320T1 (fi)
AU (1) AU638735B2 (fi)
CA (1) CA2023194C (fi)
CY (1) CY2029A (fi)
CZ (1) CZ284783B6 (fi)
DD (1) DD297169A5 (fi)
DE (2) DE3926822A1 (fi)
DK (1) DK0413277T3 (fi)
ES (1) ES2065445T3 (fi)
FI (1) FI102759B (fi)
HU (1) HU208324B (fi)
IE (1) IE65356B1 (fi)
IL (1) IL95357A (fi)
LT (1) LT3868B (fi)
NO (1) NO178433C (fi)
NZ (1) NZ234861A (fi)
PT (1) PT94982B (fi)
RU (1) RU2081880C1 (fi)
SK (1) SK280787B6 (fi)
ZA (1) ZA906381B (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4013270A1 (de) * 1990-04-26 1991-10-31 Hoechst Ag Peptide mit bradykinin-antagonistischer wirkung
EP0586613A4 (en) * 1991-04-01 1994-08-24 Cortech Inc Bradykinin antagonists
ES2123556T3 (es) 1991-04-19 1999-01-16 Scios Nova Inc Peptidos de tipo bradiquinina.
US6770741B1 (en) 1991-04-19 2004-08-03 Scios Inc. Bradykinin antagonist peptides
CA2106762C (en) * 1991-04-19 2000-10-10 Donald J. Kyle Bradykinin antagonist peptides
US5380875A (en) * 1991-06-06 1995-01-10 Hitachi Chemical Company, Ltd. Hydroxyproline derivatives and preparative process therefor
WO1993011789A1 (en) 1991-12-12 1993-06-24 Scios Nova Inc. Modified position (7) bradykinin antagonist peptides
TW199863B (fi) * 1991-12-21 1993-02-11 Hoechst Ag
TW258739B (fi) * 1992-04-04 1995-10-01 Hoechst Ag
US5541286A (en) * 1992-10-08 1996-07-30 Scios Nova Inc. Bradykinin antagonist pseudopeptide derivatives of olefinic aminoalkanoic acids
US5521158A (en) * 1992-10-08 1996-05-28 Scios Nova Inc. Pseudopeptide bradykinin receptor antagonists
US5686565A (en) * 1992-10-08 1997-11-11 Scios Inc. Bradykinin antagonist pseudopeptide derivatives of aminoalkanoic acids and related olefins
US5610142A (en) * 1992-10-08 1997-03-11 Scios Inc. Bradykinin antagonist pseudopeptide derivatives of substituted 4-keto-1,3,8-triazaspiro[4.5]decan-3-alkanoic acids
WO1994019372A1 (en) * 1993-02-17 1994-09-01 Scios Nova Inc. Cyclic bradykinin antagonist peptides
US5817756A (en) * 1993-09-09 1998-10-06 Scios Inc. Pseudo- and non-peptide bradykinin receptor antagonists
FR2739553B1 (fr) * 1995-10-06 1998-01-02 Oreal Utilisation d'antagonistes de la bradykinine pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
DE19612067A1 (de) * 1996-03-27 1997-10-02 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von chronisch fibrogenetischen Lebererkrankungen und akuten Lebererkrankungen
FR2756566B1 (fr) * 1996-12-04 1999-01-08 Fournier Ind & Sante Peptides agonistes du recepteur b2 de la bradykinine, procede de preparation et utilisation en therapeutique
PT1768966E (pt) * 2004-06-17 2012-05-23 Infinity Discovery Inc Compostos e métodos para inibir a interacção de proteínas bcl com parceiros de ligação
KR101707887B1 (ko) * 2016-11-22 2017-02-17 홍인석 방향제 시트가 부착된 포장지 제조장치 및 제조방법

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986007263A1 (en) 1985-06-13 1986-12-18 Stewart John M Bradykinin antagonist peptides
EP0247573A2 (de) 1986-05-30 1987-12-02 Hoechst Aktiengesellschaft Aminosäure-Benzotriazinylester, Verfahren zu deren Herstellung und deren Verwendung
EP0264802A2 (de) 1986-10-21 1988-04-27 Hoechst Aktiengesellschaft Synthese von Peptid-aminoalkylamiden und Peptid-hydraziden mittels Festphasenmethode

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4923963A (en) * 1987-09-02 1990-05-08 Nova Technology Limited Partnership Bradykinin antagonist peptides
WO1989001780A1 (en) * 1987-09-02 1989-03-09 Stewart John M Bradykinin antagonist peptides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986007263A1 (en) 1985-06-13 1986-12-18 Stewart John M Bradykinin antagonist peptides
EP0247573A2 (de) 1986-05-30 1987-12-02 Hoechst Aktiengesellschaft Aminosäure-Benzotriazinylester, Verfahren zu deren Herstellung und deren Verwendung
EP0264802A2 (de) 1986-10-21 1988-04-27 Hoechst Aktiengesellschaft Synthese von Peptid-aminoalkylamiden und Peptid-hydraziden mittels Festphasenmethode

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
COLOMBO R, ATHERTON E, SHEPPARD RC, WOOLLEY V: "4-Chloromethylphenoxyacetyl polystyrene and polyamide supports for solid-phase peptide synthesis", INT J PEPT PROTEIN RES., 1983, pages 118
R. B. MERRIFIELD ET AL.: "A new synthetic route to tert-butyloxycarbonylaminoacyl-4-(oxymethyl)phenylacetamidomethyl-resin, an improved support for solid-phase peptide synthesis", J. ORG. CHEM., 1978, pages 2845
R. B. MERRIFIELD: "Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide", J. AM. CHEM. SOC, 1963, pages 2149, XP002257754, DOI: doi:10.1021/ja00897a025
SCHRODES, LUBKE: "The Peptides (Vol. 1)"
WANG SS.: "p-alkoxybenzyl alcohol resin and p-alkoxybenzyloxycarbonylhydrazide resin for solid phase synthesis of protected peptide fragments.", J AM CHEM SOC., 1973, pages 1328, XP000615541, DOI: doi:10.1021/ja00785a602

Also Published As

Publication number Publication date
NO903545D0 (no) 1990-08-13
HU904989D0 (en) 1991-01-28
NO903545L (no) 1991-02-15
JP2997519B2 (ja) 2000-01-11
FI102759B1 (fi) 1999-02-15
JPH0386898A (ja) 1991-04-11
NO178433B (no) 1995-12-18
RU2081880C1 (ru) 1997-06-20
FI102759B (fi) 1999-02-15
CA2023194A1 (en) 1991-02-15
EP0413277A1 (de) 1991-02-20
CS397990A3 (en) 1992-03-18
NO178433C (no) 1996-03-27
FI903971A0 (fi) 1990-08-10
IE65356B1 (en) 1995-10-18
DK0413277T3 (da) 1995-04-18
NZ234861A (en) 1992-09-25
IL95357A (en) 1995-08-31
HUT54712A (en) 1991-03-28
EP0413277B1 (de) 1994-11-23
PT94982A (pt) 1991-04-18
HU208324B (en) 1993-09-28
SK280787B6 (sk) 2000-07-11
CA2023194C (en) 2001-09-11
ES2065445T3 (es) 1995-02-16
IL95357A0 (en) 1991-06-30
CZ284783B6 (cs) 1999-03-17
CN1049505A (zh) 1991-02-27
KR910004662A (ko) 1991-03-29
CY2029A (en) 1998-02-20
PT94982B (pt) 1997-04-30
AU6092490A (en) 1991-02-21
DD297169A5 (de) 1992-01-02
CN1034577C (zh) 1997-04-16
ATE114320T1 (de) 1994-12-15
DE59007747D1 (de) 1995-01-05
AU638735B2 (en) 1993-07-08
LTIP1466A (en) 1995-06-26
DE3926822A1 (de) 1991-02-21
IE902923A1 (en) 1991-02-27
ZA906381B (en) 1991-05-29
KR0173976B1 (ko) 1999-02-01

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