LT3416675T - Hepatito delta viruso infekcijos gydymas interferonu lambda - Google Patents

Hepatito delta viruso infekcijos gydymas interferonu lambda

Info

Publication number
LT3416675T
LT3416675T LTEP17753966.5T LT17753966T LT3416675T LT 3416675 T LT3416675 T LT 3416675T LT 17753966 T LT17753966 T LT 17753966T LT 3416675 T LT3416675 T LT 3416675T
Authority
LT
Lithuania
Prior art keywords
treatment
virus infection
hepatitis delta
delta virus
interferon lambda
Prior art date
Application number
LTEP17753966.5T
Other languages
English (en)
Lithuanian (lt)
Inventor
Eduardo Bruno MARTINS
Original Assignee
Eiger Biopharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eiger Biopharmaceuticals, Inc. filed Critical Eiger Biopharmaceuticals, Inc.
Publication of LT3416675T publication Critical patent/LT3416675T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
LTEP17753966.5T 2016-02-19 2017-02-17 Hepatito delta viruso infekcijos gydymas interferonu lambda LT3416675T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662297759P 2016-02-19 2016-02-19
PCT/US2017/018466 WO2017143253A1 (en) 2016-02-19 2017-02-17 Treatment of hepatitis delta virus infection with interferon lambda

Publications (1)

Publication Number Publication Date
LT3416675T true LT3416675T (lt) 2021-06-25

Family

ID=59625481

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP17753966.5T LT3416675T (lt) 2016-02-19 2017-02-17 Hepatito delta viruso infekcijos gydymas interferonu lambda

Country Status (17)

Country Link
US (2) US10953072B2 (https=)
EP (2) EP3957319B1 (https=)
JP (3) JP7674628B2 (https=)
KR (1) KR20180110127A (https=)
CN (1) CN108883156A (https=)
CY (1) CY1124220T1 (https=)
DK (1) DK3416675T3 (https=)
ES (2) ES2874592T3 (https=)
HR (1) HRP20210862T1 (https=)
HU (1) HUE055343T2 (https=)
LT (1) LT3416675T (https=)
PL (1) PL3416675T3 (https=)
PT (1) PT3416675T (https=)
RS (1) RS61944B1 (https=)
SI (1) SI3416675T1 (https=)
SM (1) SMT202100335T1 (https=)
WO (1) WO2017143253A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11311519B2 (en) 2014-05-01 2022-04-26 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
WO2016172342A1 (en) 2015-04-21 2016-10-27 Eiger Biopharmaceuticals, Inc. Pharmaceutical compositions comprising lonafarnib and ritonavir
JP7674628B2 (ja) 2016-02-19 2025-05-12 イーアイティー・ファーマ・インコーポレイテッド インターフェロンラムダによるデルタ型肝炎ウイルス感染の処置
GB201621728D0 (en) * 2016-12-20 2017-02-01 Ucb Biopharma Sprl Methods
CN113286605A (zh) * 2018-08-23 2021-08-20 艾格尔峰生物制药有限公司 用干扰素λ治疗丁型肝炎病毒感染
KR20220035365A (ko) 2019-07-18 2022-03-22 엔요 파마 인터페론의 부작용을 감소시키는 방법
US20230070752A1 (en) * 2019-08-21 2023-03-09 Korea Advanced Institute Of Science And Technology Novel interferon lambda variant and method of producing the same
JP2022552001A (ja) * 2019-10-16 2022-12-14 アイガー・バイオファーマシューティカルズ・インコーポレイテッド D型肝炎ウイルス感染を処置する方法
WO2021159027A1 (en) * 2020-02-06 2021-08-12 Eiger Biopharmaceuticals, Inc. Treatment of coronavirus infection with interferon lambda

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6927040B2 (en) 2000-06-30 2005-08-09 Zymogenetics, Inc. Interferon-like protein Zcyto21
US7038032B2 (en) 2001-04-20 2006-05-02 Zymogenetics, Inc. Cytokine protein family
EP1575609A4 (en) 2002-10-23 2010-12-15 Zymogenetics L L C METHOD FOR THE TREATMENT OF VIRUS INFECTIONS USING IL-28 AND IL-29
JP2006528679A (ja) 2003-04-01 2006-12-21 インターミューン インコーポレイテッド コロナウイルス感染症及びサースを治療するための組成物及び方法
EP1927600A1 (en) 2003-08-07 2008-06-04 Zymogenetics, Inc. Homogeneous preparations of IL-28 and IL-29
WO2005097165A2 (en) 2004-04-02 2005-10-20 Zymogenetics, Inc. Il-28 and il-29 cysteine mutants for treating viral infection
WO2006076014A2 (en) 2004-04-30 2006-07-20 Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Interferon-alpha constructs for use in the treatment of sars
JP2009502803A (ja) 2005-07-20 2009-01-29 ザイモジェネティクス, インコーポレイテッド Il−28およびil−29のシステイン欠失変異体、ならびにそれを用いる抗ウイルス法
CA2616004A1 (en) 2005-07-20 2007-02-01 Zymogenetics, Inc. Use of truncated cysteine il28 and il29 mutants to treat cancers and autoimmune disorders
WO2007041713A1 (en) 2005-10-04 2007-04-12 Zymogenetics, Inc. Production and purification of il-29
US9155749B2 (en) 2006-09-14 2015-10-13 Medgenics Medical Israel Ltd. Long lasting drug formulations
US10071154B2 (en) * 2008-04-04 2018-09-11 The Trustees Of The University Of Pennsylvania Vaccines and immunotherapeutics using IL-28 and compositions and methods of using the same
WO2011088126A2 (en) 2010-01-13 2011-07-21 Eiger Biopharmaceuticals, Inc. Treatment of viral infection with prenyltransferase inhibitors
TW201247216A (en) 2011-04-01 2012-12-01 Novartis Ag Treatment for infection with Hepatitis B virus alone or in combination with Hepatitis delta virus and associated liver diseases
BR112013032381B1 (pt) * 2011-06-14 2021-01-12 Globeimmune, Inc. composições à base de levedura e métodos para o tratamento ou prevenção de infecção pelo vírus da hepatite delta
BR112014004302A2 (pt) 2011-08-25 2017-06-20 Nanogen Pharmaceutical Biotechnology conjugado, composição farmacêutica, processo para preparar um conjugado, métodos para inibir a proliferação de uma célula cancerosa, para tratar um distúrbio, e para tratar um paciente
US8454947B1 (en) 2012-03-01 2013-06-04 Nanogen Pharmaceutical Biotechnology PEG-interferon lambda 1 conjugates
AU2013308045B2 (en) 2012-08-30 2018-10-04 Replicor Inc. Methods for the treatment of hepatitis B and hepatitis D infections
SG11201503459SA (en) 2012-11-02 2015-06-29 Pharmacyclics Inc Tec family kinase inhibitor adjuvant therapy
HUE044606T2 (hu) 2014-05-01 2019-11-28 Eiger Biopharmaceuticals Inc A hepatitis delta vírusfertõzés kezelése
US10076512B2 (en) 2014-05-01 2018-09-18 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
WO2016090107A2 (en) 2014-12-04 2016-06-09 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
WO2016172342A1 (en) 2015-04-21 2016-10-27 Eiger Biopharmaceuticals, Inc. Pharmaceutical compositions comprising lonafarnib and ritonavir
JP7187315B2 (ja) 2015-11-04 2022-12-12 アイガー・バイオファーマシューティカルズ・インコーポレイテッド デルタ型肝炎ウイルス感染の処置
JP7674628B2 (ja) 2016-02-19 2025-05-12 イーアイティー・ファーマ・インコーポレイテッド インターフェロンラムダによるデルタ型肝炎ウイルス感染の処置
GB201621728D0 (en) 2016-12-20 2017-02-01 Ucb Biopharma Sprl Methods
CN113286605A (zh) 2018-08-23 2021-08-20 艾格尔峰生物制药有限公司 用干扰素λ治疗丁型肝炎病毒感染
WO2021055714A1 (en) 2019-09-19 2021-03-25 Eip Pharma, Inc. Compositions and methods for treating prion disease
WO2021159027A1 (en) 2020-02-06 2021-08-12 Eiger Biopharmaceuticals, Inc. Treatment of coronavirus infection with interferon lambda

Also Published As

Publication number Publication date
ES2874592T3 (es) 2021-11-05
EP3416675B1 (en) 2021-03-24
US10953072B2 (en) 2021-03-23
HUE055343T2 (hu) 2022-05-28
EP3957319A1 (en) 2022-02-23
WO2017143253A1 (en) 2017-08-24
JP2024156840A (ja) 2024-11-06
JP7674628B2 (ja) 2025-05-12
US20190111110A1 (en) 2019-04-18
KR20180110127A (ko) 2018-10-08
SMT202100335T1 (it) 2021-07-12
JP2019505553A (ja) 2019-02-28
SI3416675T1 (sl) 2021-09-30
RS61944B1 (sr) 2021-07-30
JP2022172279A (ja) 2022-11-15
EP3416675B9 (en) 2021-07-14
CN108883156A (zh) 2018-11-23
EP3416675A1 (en) 2018-12-26
US12508297B2 (en) 2025-12-30
EP3416675A4 (en) 2020-01-08
EP3957319B1 (en) 2024-12-04
US20210228686A1 (en) 2021-07-29
HRP20210862T1 (hr) 2021-09-17
PT3416675T (pt) 2021-06-14
CY1124220T1 (el) 2022-05-27
ES3008560T3 (en) 2025-03-24
PL3416675T3 (pl) 2021-10-11
DK3416675T3 (da) 2021-06-14

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