HUE055343T2 - A hepatitis delta vírusfertõzés kezelése interferon lambdával - Google Patents

A hepatitis delta vírusfertõzés kezelése interferon lambdával

Info

Publication number
HUE055343T2
HUE055343T2 HUE17753966A HUE17753966A HUE055343T2 HU E055343 T2 HUE055343 T2 HU E055343T2 HU E17753966 A HUE17753966 A HU E17753966A HU E17753966 A HUE17753966 A HU E17753966A HU E055343 T2 HUE055343 T2 HU E055343T2
Authority
HU
Hungary
Prior art keywords
treatment
virus infection
hepatitis delta
delta virus
interferon lambda
Prior art date
Application number
HUE17753966A
Other languages
English (en)
Hungarian (hu)
Inventor
Eduardo Bruno Martins
Original Assignee
Eiger Biopharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eiger Biopharmaceuticals Inc filed Critical Eiger Biopharmaceuticals Inc
Publication of HUE055343T2 publication Critical patent/HUE055343T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HUE17753966A 2016-02-19 2017-02-17 A hepatitis delta vírusfertõzés kezelése interferon lambdával HUE055343T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662297759P 2016-02-19 2016-02-19

Publications (1)

Publication Number Publication Date
HUE055343T2 true HUE055343T2 (hu) 2022-05-28

Family

ID=59625481

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE17753966A HUE055343T2 (hu) 2016-02-19 2017-02-17 A hepatitis delta vírusfertõzés kezelése interferon lambdával

Country Status (17)

Country Link
US (2) US10953072B2 (https=)
EP (2) EP3416675B9 (https=)
JP (3) JP7674628B2 (https=)
KR (1) KR20180110127A (https=)
CN (1) CN108883156A (https=)
CY (1) CY1124220T1 (https=)
DK (1) DK3416675T3 (https=)
ES (2) ES2874592T3 (https=)
HR (1) HRP20210862T1 (https=)
HU (1) HUE055343T2 (https=)
LT (1) LT3416675T (https=)
PL (1) PL3416675T3 (https=)
PT (1) PT3416675T (https=)
RS (1) RS61944B1 (https=)
SI (1) SI3416675T1 (https=)
SM (1) SMT202100335T1 (https=)
WO (1) WO2017143253A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11311519B2 (en) 2014-05-01 2022-04-26 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
WO2016172342A1 (en) 2015-04-21 2016-10-27 Eiger Biopharmaceuticals, Inc. Pharmaceutical compositions comprising lonafarnib and ritonavir
JP7674628B2 (ja) 2016-02-19 2025-05-12 イーアイティー・ファーマ・インコーポレイテッド インターフェロンラムダによるデルタ型肝炎ウイルス感染の処置
GB201621728D0 (en) 2016-12-20 2017-02-01 Ucb Biopharma Sprl Methods
JP7571008B2 (ja) * 2018-08-23 2024-10-22 アイガー・バイオファーマシューティカルズ・インコーポレイテッド インターフェロンラムダでのデルタ肝炎ウイルス感染処置
EP3999101A1 (en) 2019-07-18 2022-05-25 ENYO Pharma Method for decreasing adverse-effects of interferon
WO2021034101A1 (ko) * 2019-08-21 2021-02-25 한국과학기술원 신규 인터페론 람다 변이체 및 이의 제조방법
EP4045034A4 (en) * 2019-10-16 2023-05-24 Eiger Biopharmaceuticals, Inc. METHODS OF TREATMENT OF HEPATITIS DELTA VIRUS INFECTIONS
EP4100047A4 (en) * 2020-02-06 2024-03-13 Eiger Biopharmaceuticals, Inc. TREATMENT OF CORONAVIRUS INFECTION WITH INTERFERON LAMBDA

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60135393D1 (de) 2000-06-30 2008-09-25 Zymogenetics Inc Allelische Variante des Interferon-ähnlichen Proteins Zcyto21
US7038032B2 (en) 2001-04-20 2006-05-02 Zymogenetics, Inc. Cytokine protein family
CA2503305A1 (en) 2002-10-23 2004-05-06 Zymogenetics, Inc. Methods for treating viral infection using il-28 and il-29
CA2520148A1 (en) 2003-04-01 2004-12-23 Intermune, Inc. Compositions and methods for treating coronavirus infection and sars
EP2251352A1 (en) 2003-08-07 2010-11-17 ZymoGenetics, L.L.C. Homogeneous preparations of IL-28 and IL-29
JP4896005B2 (ja) 2004-04-02 2012-03-14 ザイモジェネティクス リミテッド ライアビリティ カンパニー Il−28およびil−29システイン変異体を用いるウイルス感染を治療するための方法
WO2006076014A2 (en) 2004-04-30 2006-07-20 Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Interferon-alpha constructs for use in the treatment of sars
AU2006272937A1 (en) 2005-07-20 2007-02-01 Bristol-Myers Squibb Company Use of truncated cysteine IL28 and IL29 mutants to treat cancers and autoimmune disorders
EP1912668A2 (en) 2005-07-20 2008-04-23 ZymoGenetics, Inc. Il28 and il29 truncated cysteine mutants and antiviral methods of using same
CA2625208A1 (en) 2005-10-04 2007-04-12 Zymogenetics, Inc. Production and purification of il-29
CN102886052B (zh) * 2006-09-14 2014-07-30 迈德詹尼克斯医疗以色列有限公司 长效药物制剂
KR101652767B1 (ko) 2008-04-04 2016-08-31 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 Il-28을 이용한 백신 및 면역치료제, 및 그를 사용하는 방법 및 조성물
WO2011088126A2 (en) 2010-01-13 2011-07-21 Eiger Biopharmaceuticals, Inc. Treatment of viral infection with prenyltransferase inhibitors
AU2012237295A1 (en) 2011-04-01 2013-09-19 Novartis Ag Treatment for infection with Hepatitis B virus alone or in combination with Hepatitis Delta virus and associated liver diseases
CN103732250A (zh) * 2011-06-14 2014-04-16 全球免疫股份有限公司 基于酵母的治疗或预防丁型肝炎病毒感染的组合物和方法
CA2846092A1 (en) 2011-08-25 2013-02-28 Nanogen Pharmaceutical Biotechnology Peg-interferon lambda 1 conjugates
US8454947B1 (en) 2012-03-01 2013-06-04 Nanogen Pharmaceutical Biotechnology PEG-interferon lambda 1 conjugates
SG11201501255PA (en) 2012-08-30 2015-03-30 Replicor Inc Methods for the treatment of hepatitis b and hepatitis d infections
TW201427664A (zh) 2012-11-02 2014-07-16 Pharmacyclics Inc Tec家族激酶抑制劑佐劑療法
PL3137078T3 (pl) * 2014-05-01 2019-08-30 Eiger Biopharmaceuticals, Inc. Leczenie zakażenia wirusem zapalenia wątroby typu delta
US10076512B2 (en) 2014-05-01 2018-09-18 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
US20180338993A1 (en) 2014-12-04 2018-11-29 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
WO2016172342A1 (en) 2015-04-21 2016-10-27 Eiger Biopharmaceuticals, Inc. Pharmaceutical compositions comprising lonafarnib and ritonavir
EP3370723B1 (en) * 2015-11-04 2020-12-16 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
JP7674628B2 (ja) 2016-02-19 2025-05-12 イーアイティー・ファーマ・インコーポレイテッド インターフェロンラムダによるデルタ型肝炎ウイルス感染の処置
GB201621728D0 (en) 2016-12-20 2017-02-01 Ucb Biopharma Sprl Methods
JP7571008B2 (ja) 2018-08-23 2024-10-22 アイガー・バイオファーマシューティカルズ・インコーポレイテッド インターフェロンラムダでのデルタ肝炎ウイルス感染処置
US20220387432A1 (en) 2019-09-19 2022-12-08 Eip Pharma, Inc. Compositions and methods for treating prion disease
EP4100047A4 (en) 2020-02-06 2024-03-13 Eiger Biopharmaceuticals, Inc. TREATMENT OF CORONAVIRUS INFECTION WITH INTERFERON LAMBDA

Also Published As

Publication number Publication date
EP3416675B1 (en) 2021-03-24
KR20180110127A (ko) 2018-10-08
SMT202100335T1 (it) 2021-07-12
EP3416675A1 (en) 2018-12-26
US20210228686A1 (en) 2021-07-29
EP3416675A4 (en) 2020-01-08
US12508297B2 (en) 2025-12-30
HRP20210862T1 (hr) 2021-09-17
WO2017143253A1 (en) 2017-08-24
JP2022172279A (ja) 2022-11-15
JP7674628B2 (ja) 2025-05-12
JP2024156840A (ja) 2024-11-06
CN108883156A (zh) 2018-11-23
US10953072B2 (en) 2021-03-23
EP3957319A1 (en) 2022-02-23
PT3416675T (pt) 2021-06-14
RS61944B1 (sr) 2021-07-30
ES3008560T3 (en) 2025-03-24
EP3416675B9 (en) 2021-07-14
US20190111110A1 (en) 2019-04-18
SI3416675T1 (sl) 2021-09-30
ES2874592T3 (es) 2021-11-05
CY1124220T1 (el) 2022-05-27
DK3416675T3 (da) 2021-06-14
EP3957319B1 (en) 2024-12-04
JP2019505553A (ja) 2019-02-28
PL3416675T3 (pl) 2021-10-11
LT3416675T (lt) 2021-06-25

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