LT3201320T - Didelio aktyvumo rūgštinė alfa-gliukozidazė su sustiprintais karbohidratais - Google Patents
Didelio aktyvumo rūgštinė alfa-gliukozidazė su sustiprintais karbohidrataisInfo
- Publication number
- LT3201320T LT3201320T LTEPPCT/US2015/053252T LTUS2015053252T LT3201320T LT 3201320 T LT3201320 T LT 3201320T LT US2015053252 T LTUS2015053252 T LT US2015053252T LT 3201320 T LT3201320 T LT 3201320T
- Authority
- LT
- Lithuania
- Prior art keywords
- glucosidase
- highly potent
- acid alpha
- carbohydrates
- enhanced
- Prior art date
Links
- 102100024295 Maltase-glucoamylase Human genes 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 108010028144 alpha-Glucosidases Proteins 0.000 title 1
- 150000001720 carbohydrates Chemical class 0.000 title 1
- 235000014633 carbohydrates Nutrition 0.000 title 1
- 230000003389 potentiating effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2465—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on alpha-galactose-glycoside bonds, e.g. alpha-galactosidase (3.2.1.22)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/0102—Alpha-glucosidase (3.2.1.20)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462057847P | 2014-09-30 | 2014-09-30 | |
| US201462057842P | 2014-09-30 | 2014-09-30 | |
| US201562112463P | 2015-02-05 | 2015-02-05 | |
| US201562135345P | 2015-03-19 | 2015-03-19 | |
| PCT/US2015/053252 WO2016054231A1 (en) | 2014-09-30 | 2015-09-30 | Highly potent acid alpha-glucosidase with enhanced carbohydrates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3201320T true LT3201320T (lt) | 2024-01-25 |
Family
ID=55631441
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEPPCT/US2015/053252T LT3201320T (lt) | 2014-09-30 | 2015-09-30 | Didelio aktyvumo rūgštinė alfa-gliukozidazė su sustiprintais karbohidratais |
Country Status (33)
| Country | Link |
|---|---|
| US (5) | US10208299B2 (lt) |
| EP (2) | EP4273241A3 (lt) |
| JP (3) | JP6851964B2 (lt) |
| KR (3) | KR102306577B1 (lt) |
| CN (2) | CN107075468B (lt) |
| AU (2) | AU2015325028B2 (lt) |
| BR (1) | BR112017005810A2 (lt) |
| CA (2) | CA2961762C (lt) |
| CL (1) | CL2017000722A1 (lt) |
| CO (1) | CO2017002776A2 (lt) |
| CR (1) | CR20170107A (lt) |
| DK (1) | DK3201320T3 (lt) |
| DO (1) | DOP2017000079A (lt) |
| EA (1) | EA038986B1 (lt) |
| EC (1) | ECSP17019103A (lt) |
| FI (2) | FI3201320T3 (lt) |
| HR (1) | HRP20240041T1 (lt) |
| IL (4) | IL307587A (lt) |
| LT (1) | LT3201320T (lt) |
| MX (2) | MX2017003989A (lt) |
| MY (1) | MY186336A (lt) |
| NI (1) | NI201700039A (lt) |
| PE (1) | PE20170906A1 (lt) |
| PH (1) | PH12017500455A1 (lt) |
| PL (1) | PL3201320T3 (lt) |
| PT (1) | PT3201320T (lt) |
| RS (1) | RS65066B1 (lt) |
| SG (2) | SG11201702114TA (lt) |
| SI (1) | SI3201320T1 (lt) |
| SV (1) | SV2017005416A (lt) |
| TN (1) | TN2017000082A1 (lt) |
| WO (1) | WO2016054231A1 (lt) |
| ZA (2) | ZA201701945B (lt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3201320T (pt) | 2014-09-30 | 2024-01-12 | Amicus Therapeutics Inc | Alfa-glucosidase ácida altamente potente com hidratos de carbono intensificados |
| KR102510941B1 (ko) * | 2015-12-30 | 2023-03-20 | 아미쿠스 세라퓨틱스, 인코포레이티드 | 폼페병 치료용의 강화된 산 알파-글루코시다제 |
| HUE054733T2 (hu) * | 2015-12-30 | 2021-09-28 | Amicus Therapeutics Inc | Megnövelt savas alfa-glükozidáz Pompe-kór kezelésére |
| KR102343162B1 (ko) * | 2016-03-30 | 2021-12-23 | 아미쿠스 세라퓨틱스, 인코포레이티드 | 고 m6p 재조합 단백질의 선택 방법 |
| KR102618519B1 (ko) | 2016-03-30 | 2023-12-28 | 아미쿠스 세라퓨틱스, 인코포레이티드 | 재조합 산 알파-글루코시다제를 포함하는 제형 |
| EP3436577A1 (en) * | 2016-03-30 | 2019-02-06 | Amicus Therapeutics, Inc. | Method for selection of high m6p recombinant proteins |
| TW201829770A (zh) * | 2017-01-10 | 2018-08-16 | 美商阿米庫斯醫療股份有限公司 | 用於治療fabry氏病之重組α-半乳糖苷酶A |
| EA039750B1 (ru) * | 2017-03-30 | 2022-03-10 | Амикус Терапьютикс, Инк. | Способ отбора рекомбинантных белков с высоким содержанием m6p |
| CA3063615A1 (en) * | 2017-05-15 | 2018-11-22 | Amicus Therapeutics, Inc. | Recombinant human acid alpha-glucosidase |
| CA3149955A1 (en) | 2019-09-06 | 2021-03-11 | Kumar DHANASEKHARAN | Method for capturing and purification of biologics |
| BR112023016212A2 (pt) * | 2021-02-11 | 2023-11-28 | Amicus Therapeutics Inc | Alfa-glucosidase ácida humana recombinante e usos da mesma |
| WO2023150387A1 (en) * | 2022-02-07 | 2023-08-10 | M6P Therapeutics, Inc. | Compositions comprising acid alpha glucosidase and methods of use thereof |
| WO2023215865A1 (en) * | 2022-05-05 | 2023-11-09 | Amicus Therapeutics, Inc. | Methods for treating pompe disease |
Family Cites Families (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4837237A (en) | 1985-07-09 | 1989-06-06 | Fred Hutchinson Cancer Research Center | Therapy using glucosidase processing inhibitors |
| US5879680A (en) | 1987-12-23 | 1999-03-09 | The United States Of America As Represented By The Department Of Health And Human Services | Cloned DNA for synthesizing unique glucocerebrosidase |
| US4985445A (en) | 1988-02-12 | 1991-01-15 | Meiji Seika Kaisha, Ltd. | Cancer cell metastasis inhibitors and novel compounds |
| US6451600B1 (en) | 1989-12-22 | 2002-09-17 | Genzyme Corporation | Enzymatically active recombinant glucocerebrosidase |
| US5236838A (en) | 1988-12-23 | 1993-08-17 | Genzyme Corporation | Enzymatically active recombinant glucocerebrosidase |
| US5179023A (en) | 1989-03-24 | 1993-01-12 | Research Corporation Technologies, Inc. | Recombinant α-galactosidase a therapy for Fabry disease |
| US5011829A (en) | 1989-06-02 | 1991-04-30 | G. D. Searle & Co. | Pharmaceutical composition and method of inhibiting virus |
| US5103008A (en) | 1989-08-17 | 1992-04-07 | Monsanto Company | Compound, N-butyl-deoxynojirimycin-6-phosphate |
| US5401650A (en) | 1990-10-24 | 1995-03-28 | The Mount Sinai School Of Medicine Of The City University Of New York | Cloning and expression of biologically active α-galactosidase A |
| US5399567A (en) | 1993-05-13 | 1995-03-21 | Monsanto Company | Method of treating cholera |
| US6118045A (en) | 1995-08-02 | 2000-09-12 | Pharming B.V. | Lysosomal proteins produced in the milk of transgenic animals |
| US6458574B1 (en) | 1996-09-12 | 2002-10-01 | Transkaryotic Therapies, Inc. | Treatment of a α-galactosidase a deficiency |
| US6083725A (en) | 1996-09-13 | 2000-07-04 | Transkaryotic Therapies, Inc. | Tranfected human cells expressing human α-galactosidase A protein |
| US6210666B1 (en) | 1997-10-21 | 2001-04-03 | Orphan Medical, Inc. | Truncated α-galactosidase A to treat fabry disease |
| AU753336B2 (en) | 1997-11-10 | 2002-10-17 | G.D. Searle & Co. | Use of alkylated iminosugars to treat multidrug resistance |
| US6465488B1 (en) | 1997-12-11 | 2002-10-15 | Chancellor, Masters & Scholars Of The University Of Oxford | Inhibition of glycolipid biosynthesis |
| US6274597B1 (en) | 1998-06-01 | 2001-08-14 | Mount Sinai School Of Medicine Of New York University | Method of enhancing lysosomal α-Galactosidase A |
| WO2000034451A1 (en) | 1998-12-07 | 2000-06-15 | Pharming Intellectual Property B.V. | Treatment of pompe's disease |
| US6545021B1 (en) | 1999-02-12 | 2003-04-08 | G.D. Searle & Co. | Use of substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds for treating hepatitis virus infections |
| EP1196190B1 (en) | 1999-07-26 | 2003-03-19 | G.D. SEARLE & CO. | Use of long-chain n-alkyl derivatives of deoxynojirimycin and a glucocerebrosidase enzyme for the manufacture of a medicament for the treatment of glycolipid storage diseases |
| US6642038B1 (en) | 1999-09-14 | 2003-11-04 | Genzyme Glycobiology Research Institute, Inc. | GlcNAc phosphotransferase of the lysosomal targeting pathway |
| WO2001097829A2 (en) | 2000-06-19 | 2001-12-27 | Genzyme Corporation | Combination enzyme replacement, gene therapy and small molecule therapy for lysosomal storage diseases |
| US20040204379A1 (en) | 2000-06-19 | 2004-10-14 | Cheng Seng H. | Combination enzyme replacement, gene therapy and small molecule therapy for lysosomal storage diseases |
| DK1301201T3 (da) | 2000-07-18 | 2007-04-02 | Univ Duke | Behandling af glycogenosis type II |
| CN1638739A (zh) | 2000-08-18 | 2005-07-13 | 法玛西雅厄普约翰美国公司 | 治疗成瘾性障碍的化合物 |
| US7723296B2 (en) * | 2001-01-18 | 2010-05-25 | Genzyme Corporation | Methods for introducing mannose-6-phosphate and other oligosaccharides onto glycoproteins and its application thereof |
| DE60224816T2 (de) | 2001-04-30 | 2009-01-22 | ZyStor Therapeutics, Inc., Milwaukee | Subzelluläres targeting von therapeutischen proteinen |
| US7560424B2 (en) | 2001-04-30 | 2009-07-14 | Zystor Therapeutics, Inc. | Targeted therapeutic proteins |
| US20030072761A1 (en) | 2001-10-16 | 2003-04-17 | Lebowitz Jonathan | Methods and compositions for targeting proteins across the blood brain barrier |
| MXPA04003640A (es) | 2001-10-16 | 2005-04-11 | Rxkinetix Inc | Formulaciones de proteina de alta concentracion y metodo de fabricacion. |
| WO2003086452A2 (en) | 2002-04-05 | 2003-10-23 | Genzyme Corporation | Methods of enhancing lysosomal storage disease therapy |
| CA2814767C (en) | 2003-01-31 | 2016-03-15 | Mount Sinai School Of Medicine Of New York University | Combination therapy for treating protein deficiency disorders |
| FR2861991B1 (fr) | 2003-11-07 | 2008-01-18 | Centre Nat Rech Scient | Utilisation d'inhibiteurs de glucosidase pour une therapie de la mucoviscidose |
| US20080014188A1 (en) * | 2004-02-06 | 2008-01-17 | Zankel Todd C | Manufacture of Highly Phosphorylated Lysosomal Enzymes and Uses Thereof |
| EP1716232B9 (en) | 2004-02-10 | 2010-10-13 | ZyStor Therapeutics , Inc. | Acid alpha-glucosidase and fragments thereof |
| US20060142234A1 (en) | 2004-12-23 | 2006-06-29 | Guohua Chen | Injectable non-aqueous suspension |
| KR20080025373A (ko) | 2005-05-17 | 2008-03-20 | 아미쿠스 세라퓨틱스, 인코포레이티드 | 1-데옥시노지리마이신 및 유도체를 이용한 폼페병의 치료방법 |
| CN101636200A (zh) * | 2006-11-13 | 2010-01-27 | 齐斯特治疗公司 | 用于治疗庞贝氏症的方法 |
| JP2010509344A (ja) | 2006-11-13 | 2010-03-25 | ザイストール セラピューティクス， インコーポレイテッド | ポンペ病を治療するための方法 |
| WO2008112525A2 (en) | 2007-03-09 | 2008-09-18 | Link Medicine Corporation | Treatment of lysosomal storage diseases |
| CA2685332A1 (en) | 2007-04-26 | 2008-11-06 | Amicus Therapeutics, Inc. | Dosing regimens for the treatment of lysosomal storage diseases using pharmacological chaperones |
| US20100317690A1 (en) | 2007-11-21 | 2010-12-16 | Summit Corporation Plc | Treatment of protein folding disorders |
| WO2009075815A1 (en) | 2007-12-07 | 2009-06-18 | Duke University | Immunomodulating gene therapy |
| SI3470077T1 (sl) | 2008-02-12 | 2020-12-31 | Amicus Therapeutics, Inc. | Postopek za napovedovanje odgovora na zdravljenje bolezni s farmakološkim spremljevalcem |
| AU2009223125A1 (en) | 2008-03-12 | 2009-09-17 | Amicus Therapeutics, Inc. | Assays for diagnosing and evaluating treatment options for Pompe disease |
| CA2718182A1 (en) | 2008-03-12 | 2009-09-17 | Amicus Therapeutics, Inc. | Treatment of pompe disease with specific pharmacological chaperones and monitoring treatment using surrogate markers |
| EP3778652A1 (en) * | 2008-05-07 | 2021-02-17 | BioMarin Pharmaceutical Inc. | Lysosomal targeting peptides and uses thereof |
| WO2010015816A2 (en) | 2008-08-06 | 2010-02-11 | Summit Corporation Plc | Treatment of lysosomal storage disorders and other proteostatic diseases |
| WO2010056746A1 (en) | 2008-11-11 | 2010-05-20 | Amicus Therapeutics, Inc. | Therapy regimens, dosing regimens and stable medicaments for the treatment of pompe disease |
| LT2889043T (lt) | 2008-12-16 | 2019-07-10 | Genzyme Corporation | Sintetiniai tarpiniai junginiai oligosacharido-baltymo konjugatų gamybai |
| WO2010096369A1 (en) * | 2009-02-18 | 2010-08-26 | Amicus Therapeutics, Inc. | Mouse model for pompe disease and methods of use thereof |
| CN102625661B (zh) | 2009-04-09 | 2015-05-27 | 阿米库斯治疗学公司 | 用于预防和/或治疗溶酶体贮积失调的方法 |
| US8785168B2 (en) | 2009-06-17 | 2014-07-22 | Biomarin Pharmaceutical Inc. | Formulations for lysosomal enzymes |
| JP5415170B2 (ja) | 2009-07-21 | 2014-02-12 | 富士フイルム株式会社 | 複眼撮像装置 |
| WO2011039634A2 (en) | 2009-09-29 | 2011-04-07 | Universiteit Gent | Hydrolysis of mannose-1-phospho-6-mannose linkage to phospho-6-mannose |
| WO2011109600A1 (en) | 2010-03-05 | 2011-09-09 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for modifying the glycosylation pattern of a polypeptide |
| CA2812870C (en) | 2010-09-29 | 2020-06-09 | Oxyrane Uk Limited | Mannosidases capable of uncapping mannose-1-phospho-6-mannose linkages and demannosylating phosphorylated n-glycans and methods of facilitating mammalian cellular uptake of glycoproteins |
| WO2012145644A1 (en) | 2011-04-22 | 2012-10-26 | Genzyme Corporation | Modified acid alpha glucosidase with accelerated processing |
| PL2714752T3 (pl) * | 2011-05-27 | 2018-04-30 | Amicus Therapeutics, Inc. | Sposoby sprzęgania peptydów nakierowanych na rekombinowane enzymy lizosomalne dla poprawy leczenia lizosomalnych chorób spichrzeniowych |
| WO2013013017A2 (en) * | 2011-07-21 | 2013-01-24 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for modifying the glycosylation of lysosomal storage disorder therapeutics |
| WO2013016249A2 (en) * | 2011-07-22 | 2013-01-31 | Insight Photonic Solutions, Inc. | System and method of dynamic and adaptive creation of a wavelength-continuous and prescribed wavelength versus time sweep from a laser |
| WO2013091897A1 (en) | 2011-12-22 | 2013-06-27 | Centogene Gmbh | Combination of a compound having the ability to rearrange a lysosomal enzyme and ambroxol and/or a derivative of ambroxol |
| JP6236406B2 (ja) | 2012-03-07 | 2017-11-22 | アミカス セラピューティックス インコーポレイテッド | ポンペ病の処置のための高濃度α−グルコシダーゼ組成物 |
| RS61598B1 (sr) * | 2012-05-03 | 2021-04-29 | Amicus Therapeutics Inc | Režimi doziranja za tretman pompeove bolesti |
| CA2915127A1 (en) | 2012-06-06 | 2013-12-12 | Giancarlo PARENTI | Allosteric chaperones and uses thereof |
| TWI529396B (zh) | 2014-07-18 | 2016-04-11 | Mpi Corp | Probe card and its transfer circuit board and signal feed structure |
| PT3201320T (pt) | 2014-09-30 | 2024-01-12 | Amicus Therapeutics Inc | Alfa-glucosidase ácida altamente potente com hidratos de carbono intensificados |
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2015
- 2015-09-30 PT PT158456640T patent/PT3201320T/pt unknown
- 2015-09-30 IL IL307587A patent/IL307587A/en unknown
- 2015-09-30 CA CA2961762A patent/CA2961762C/en active Active
- 2015-09-30 KR KR1020177011346A patent/KR102306577B1/ko active Application Filing
- 2015-09-30 CN CN201580052512.5A patent/CN107075468B/zh active Active
- 2015-09-30 SI SI201531983T patent/SI3201320T1/sl unknown
- 2015-09-30 EA EA201790724A patent/EA038986B1/ru unknown
- 2015-09-30 BR BR112017005810A patent/BR112017005810A2/pt not_active Application Discontinuation
- 2015-09-30 SG SG11201702114TA patent/SG11201702114TA/en unknown
- 2015-09-30 HR HRP20240041TT patent/HRP20240041T1/hr unknown
- 2015-09-30 LT LTEPPCT/US2015/053252T patent/LT3201320T/lt unknown
- 2015-09-30 CN CN202111483006.5A patent/CN114540327A/zh active Pending
- 2015-09-30 CA CA3228032A patent/CA3228032A1/en active Pending
- 2015-09-30 SG SG10202003753PA patent/SG10202003753PA/en unknown
- 2015-09-30 PL PL15845664.0T patent/PL3201320T3/pl unknown
- 2015-09-30 WO PCT/US2015/053252 patent/WO2016054231A1/en active Application Filing
- 2015-09-30 CR CR20170107A patent/CR20170107A/es unknown
- 2015-09-30 KR KR1020217030450A patent/KR102455814B1/ko active IP Right Grant
- 2015-09-30 EP EP23191307.0A patent/EP4273241A3/en active Pending
- 2015-09-30 PE PE2017000507A patent/PE20170906A1/es unknown
- 2015-09-30 TN TN2017000082A patent/TN2017000082A1/en unknown
- 2015-09-30 RS RS20240027A patent/RS65066B1/sr unknown
- 2015-09-30 MY MYPI2017000365A patent/MY186336A/en unknown
- 2015-09-30 AU AU2015325028A patent/AU2015325028B2/en active Active
- 2015-09-30 MX MX2017003989A patent/MX2017003989A/es unknown
- 2015-09-30 JP JP2017516917A patent/JP6851964B2/ja active Active
- 2015-09-30 DK DK15845664.0T patent/DK3201320T3/da active
- 2015-09-30 EP EP15845664.0A patent/EP3201320B1/en active Active
- 2015-09-30 KR KR1020227035610A patent/KR20220146662A/ko not_active Application Discontinuation
- 2015-09-30 FI FIEP15845664.0T patent/FI3201320T3/fi active
- 2015-09-30 US US15/515,808 patent/US10208299B2/en active Active
- 2015-09-30 IL IL289383A patent/IL289383B2/en unknown
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2017
- 2017-03-10 PH PH12017500455A patent/PH12017500455A1/en unknown
- 2017-03-14 IL IL251152A patent/IL251152B/en active IP Right Grant
- 2017-03-20 ZA ZA2017/01945A patent/ZA201701945B/en unknown
- 2017-03-20 DO DO2017000079A patent/DOP2017000079A/es unknown
- 2017-03-23 CO CONC2017/0002776A patent/CO2017002776A2/es unknown
- 2017-03-27 CL CL2017000722A patent/CL2017000722A1/es unknown
- 2017-03-27 MX MX2021014565A patent/MX2021014565A/es unknown
- 2017-03-28 EC ECIEPI201719103A patent/ECSP17019103A/es unknown
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2019
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