LT3122878T - Terapija mrnr, skirta akių ligų gydymui - Google Patents
Terapija mrnr, skirta akių ligų gydymuiInfo
- Publication number
- LT3122878T LT3122878T LTEP15767977.0T LT15767977T LT3122878T LT 3122878 T LT3122878 T LT 3122878T LT 15767977 T LT15767977 T LT 15767977T LT 3122878 T LT3122878 T LT 3122878T
- Authority
- LT
- Lithuania
- Prior art keywords
- treatment
- ocular diseases
- mrna therapy
- mrna
- therapy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
- A61K48/0066—Manipulation of the nucleic acid to modify its expression pattern, e.g. enhance its duration of expression, achieved by the presence of particular introns in the delivered nucleic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0075—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the delivery route, e.g. oral, subcutaneous
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Ophthalmology & Optometry (AREA)
- Biochemistry (AREA)
- Dispersion Chemistry (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461969483P | 2014-03-24 | 2014-03-24 | |
PCT/US2015/021403 WO2015148247A1 (en) | 2014-03-24 | 2015-03-19 | Mrna therapy for the treatment of ocular diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
LT3122878T true LT3122878T (lt) | 2019-02-11 |
Family
ID=54196241
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEP15767977.0T LT3122878T (lt) | 2014-03-24 | 2015-03-19 | Terapija mrnr, skirta akių ligų gydymui |
Country Status (15)
Country | Link |
---|---|
US (2) | US20170143848A1 (hr) |
EP (3) | EP3450553B1 (hr) |
CY (1) | CY1121348T1 (hr) |
DK (2) | DK3450553T3 (hr) |
ES (2) | ES2774552T3 (hr) |
HR (1) | HRP20190117T1 (hr) |
HU (1) | HUE041940T2 (hr) |
LT (1) | LT3122878T (hr) |
ME (1) | ME03314B (hr) |
PL (1) | PL3122878T3 (hr) |
PT (1) | PT3122878T (hr) |
RS (1) | RS58337B1 (hr) |
SI (1) | SI3122878T1 (hr) |
TR (1) | TR201900649T4 (hr) |
WO (1) | WO2015148247A1 (hr) |
Families Citing this family (60)
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NZ600616A (en) | 2009-12-01 | 2014-11-28 | Shire Human Genetic Therapies | Delivery of mrna for the augmentation of proteins and enzymes in human genetic diseases |
DK2718269T3 (en) | 2011-06-08 | 2018-04-09 | Translate Bio Inc | SPLITLY LIPIDS |
EP3613852A3 (en) | 2011-07-22 | 2020-04-22 | President and Fellows of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
US9163284B2 (en) | 2013-08-09 | 2015-10-20 | President And Fellows Of Harvard College | Methods for identifying a target site of a Cas9 nuclease |
WO2015048744A2 (en) | 2013-09-30 | 2015-04-02 | Moderna Therapeutics, Inc. | Polynucleotides encoding immune modulating polypeptides |
US10323076B2 (en) | 2013-10-03 | 2019-06-18 | Modernatx, Inc. | Polynucleotides encoding low density lipoprotein receptor |
US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
US10077453B2 (en) | 2014-07-30 | 2018-09-18 | President And Fellows Of Harvard College | CAS9 proteins including ligand-dependent inteins |
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IL294014B1 (en) | 2015-10-23 | 2024-03-01 | Harvard College | Nucleobase editors and their uses |
JP7080172B2 (ja) | 2015-12-10 | 2022-06-03 | モデルナティエックス インコーポレイテッド | 治療薬の送達のための組成物及び方法 |
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AU2017306676B2 (en) | 2016-08-03 | 2024-02-22 | President And Fellows Of Harvard College | Adenosine nucleobase editors and uses thereof |
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WO2018039438A1 (en) | 2016-08-24 | 2018-03-01 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
CN110214180A (zh) | 2016-10-14 | 2019-09-06 | 哈佛大学的校长及成员们 | 核碱基编辑器的aav递送 |
CA3041307A1 (en) | 2016-10-21 | 2018-04-26 | Giuseppe Ciaramella | Human cytomegalovirus vaccine |
JP7121005B2 (ja) * | 2016-11-23 | 2022-08-17 | メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ | 生物学的製剤の粒子媒介送達 |
WO2018119359A1 (en) | 2016-12-23 | 2018-06-28 | President And Fellows Of Harvard College | Editing of ccr5 receptor gene to protect against hiv infection |
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US11898179B2 (en) | 2017-03-09 | 2024-02-13 | President And Fellows Of Harvard College | Suppression of pain by gene editing |
JP2020510439A (ja) | 2017-03-10 | 2020-04-09 | プレジデント アンド フェローズ オブ ハーバード カレッジ | シトシンからグアニンへの塩基編集因子 |
KR20190130613A (ko) | 2017-03-23 | 2019-11-22 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 핵산 프로그램가능한 dna 결합 단백질을 포함하는 핵염기 편집제 |
WO2018209320A1 (en) | 2017-05-12 | 2018-11-15 | President And Fellows Of Harvard College | Aptazyme-embedded guide rnas for use with crispr-cas9 in genome editing and transcriptional activation |
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WO2019023680A1 (en) | 2017-07-28 | 2019-01-31 | President And Fellows Of Harvard College | METHODS AND COMPOSITIONS FOR EVOLUTION OF BASIC EDITORS USING PHAGE-ASSISTED CONTINUOUS EVOLUTION (PACE) |
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US11319532B2 (en) | 2017-08-30 | 2022-05-03 | President And Fellows Of Harvard College | High efficiency base editors comprising Gam |
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WO2019169228A1 (en) * | 2018-03-01 | 2019-09-06 | Georgia Tech Research Corporation | Methods and compositions for mrna-based modulation and detection of cell phenotypes |
CA3103436A1 (en) | 2018-06-11 | 2019-12-19 | The Regents Of The University Of California | Demethylation to treat eye disease |
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WO2020051223A1 (en) | 2018-09-04 | 2020-03-12 | The Board Of Regents Of The University Of Texas System | Compositions and methods for organ specific delivery of nucleic acids |
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JP2022512578A (ja) | 2018-10-09 | 2022-02-07 | ザ ユニヴァーシティ オブ ブリティッシュ コロンビア | 有機溶媒不含かつ劣化剤不含のトランスフェクション・コンピテント・ベシクルを含む組成物及びシステム並びにそれらに関連する方法 |
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-
2015
- 2015-03-19 RS RS20190099A patent/RS58337B1/sr unknown
- 2015-03-19 PT PT15767977T patent/PT3122878T/pt unknown
- 2015-03-19 EP EP18201321.9A patent/EP3450553B1/en active Active
- 2015-03-19 LT LTEP15767977.0T patent/LT3122878T/lt unknown
- 2015-03-19 DK DK18201321.9T patent/DK3450553T3/da active
- 2015-03-19 ES ES18201321T patent/ES2774552T3/es active Active
- 2015-03-19 EP EP15767977.0A patent/EP3122878B1/en active Active
- 2015-03-19 TR TR2019/00649T patent/TR201900649T4/tr unknown
- 2015-03-19 ES ES15767977T patent/ES2707969T3/es active Active
- 2015-03-19 ME MEP-2019-13A patent/ME03314B/me unknown
- 2015-03-19 PL PL15767977T patent/PL3122878T3/pl unknown
- 2015-03-19 HU HUE15767977A patent/HUE041940T2/hu unknown
- 2015-03-19 SI SI201530559T patent/SI3122878T1/sl unknown
- 2015-03-19 WO PCT/US2015/021403 patent/WO2015148247A1/en active Application Filing
- 2015-03-19 US US15/128,303 patent/US20170143848A1/en not_active Abandoned
- 2015-03-19 DK DK15767977.0T patent/DK3122878T3/en active
- 2015-03-19 EP EP19218561.9A patent/EP3699274A1/en active Pending
-
2019
- 2019-01-18 HR HRP20190117TT patent/HRP20190117T1/hr unknown
- 2019-01-22 CY CY20191100085T patent/CY1121348T1/el unknown
-
2022
- 2022-02-03 US US17/592,335 patent/US20220354968A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
ME03314B (me) | 2019-10-20 |
CY1121348T1 (el) | 2020-05-29 |
SI3122878T1 (sl) | 2019-05-31 |
HUE041940T2 (hu) | 2019-06-28 |
WO2015148247A1 (en) | 2015-10-01 |
PL3122878T3 (pl) | 2019-06-28 |
PT3122878T (pt) | 2019-02-01 |
EP3450553A1 (en) | 2019-03-06 |
US20220354968A1 (en) | 2022-11-10 |
DK3450553T3 (da) | 2020-02-10 |
EP3122878A4 (en) | 2017-08-30 |
EP3699274A1 (en) | 2020-08-26 |
US20170143848A1 (en) | 2017-05-25 |
RS58337B1 (sr) | 2019-03-29 |
TR201900649T4 (tr) | 2019-02-21 |
ES2707969T3 (es) | 2019-04-08 |
DK3122878T3 (en) | 2019-02-04 |
EP3450553B1 (en) | 2019-12-25 |
ES2774552T3 (es) | 2020-07-21 |
HRP20190117T1 (hr) | 2019-04-19 |
EP3122878B1 (en) | 2018-10-24 |
EP3122878A1 (en) | 2017-02-01 |
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