LT2254904T - Oligopeptidiniai junginiai ir jų panaudojimas - Google Patents

Oligopeptidiniai junginiai ir jų panaudojimas

Info

Publication number
LT2254904T
LT2254904T LTEP09713402.7T LT09713402T LT2254904T LT 2254904 T LT2254904 T LT 2254904T LT 09713402 T LT09713402 T LT 09713402T LT 2254904 T LT2254904 T LT 2254904T
Authority
LT
Lithuania
Prior art keywords
oligopeptidic compounds
oligopeptidic
compounds
Prior art date
Application number
LTEP09713402.7T
Other languages
English (en)
Inventor
Marit Otterlei
Per Aas
Emadoldin Feyzi
Original Assignee
Apim Therapeutics As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apim Therapeutics As filed Critical Apim Therapeutics As
Publication of LT2254904T publication Critical patent/LT2254904T/lt

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4738Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y306/00Hydrolases acting on acid anhydrides (3.6)
    • C12Y306/03Hydrolases acting on acid anhydrides (3.6) acting on acid anhydrides; catalysing transmembrane movement of substances (3.6.3)
    • C12Y306/03044Xenobiotic-transporting ATPase (3.6.3.44)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/09Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/10Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease
LTEP09713402.7T 2008-02-22 2009-02-20 Oligopeptidiniai junginiai ir jų panaudojimas LT2254904T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0803352.4A GB0803352D0 (en) 2008-02-22 2008-02-22 Oligopeptidic compounds and uses thereof
US10058408P 2008-09-26 2008-09-26
PCT/GB2009/000489 WO2009104001A2 (en) 2008-02-22 2009-02-20 Oligopeptidic compounds and uses thereof

Publications (1)

Publication Number Publication Date
LT2254904T true LT2254904T (lt) 2018-06-11

Family

ID=39284467

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP09713402.7T LT2254904T (lt) 2008-02-22 2009-02-20 Oligopeptidiniai junginiai ir jų panaudojimas
LTEP18155330.6T LT3338790T (lt) 2008-02-22 2009-02-20 Oligopeptidiniai junginiai ir jų panaudojimas

Family Applications After (1)

Application Number Title Priority Date Filing Date
LTEP18155330.6T LT3338790T (lt) 2008-02-22 2009-02-20 Oligopeptidiniai junginiai ir jų panaudojimas

Country Status (23)

Country Link
US (3) US8871724B2 (lt)
EP (2) EP3338790B1 (lt)
JP (2) JP5863240B2 (lt)
KR (3) KR101758671B1 (lt)
CN (1) CN102015758B (lt)
AU (1) AU2009216567B2 (lt)
BR (1) BRPI0908853B1 (lt)
CA (1) CA2715940C (lt)
DK (2) DK3338790T3 (lt)
ES (2) ES2912122T3 (lt)
GB (1) GB0803352D0 (lt)
HR (3) HRP20220585T3 (lt)
HU (2) HUE037737T2 (lt)
IL (1) IL207384B (lt)
LT (2) LT2254904T (lt)
MX (1) MX2010008989A (lt)
NO (1) NO2254904T3 (lt)
PL (2) PL3338790T3 (lt)
PT (2) PT3338790T (lt)
RU (1) RU2549675C2 (lt)
TR (1) TR201807218T4 (lt)
WO (1) WO2009104001A2 (lt)
ZA (2) ZA201005506B (lt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0803352D0 (en) * 2008-02-22 2008-04-02 Ntnu Technology Transfer As Oligopeptidic compounds and uses thereof
GB201001602D0 (en) * 2010-02-01 2010-03-17 Cytovation As Oligopeptidic compounds and uses therof
US20130059773A1 (en) * 2010-02-24 2013-03-07 Veronique Witko-Sarsat Compounds for the treatment of inflammation and neutropenia
US10106855B2 (en) 2012-11-09 2018-10-23 The Johns Hopkins University Genetic assay to determine prognosis in Polycythemia Vera patients
US9744219B2 (en) 2013-02-13 2017-08-29 Yale University Compositions and methods for treating pathological calcification and ossification
US10526385B2 (en) 2013-10-17 2020-01-07 Bao Kang Biomedical Healthcare Inc YAP protein inhibiting polypeptide and application thereof
GB201319621D0 (en) 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Antimicrobial agents and their use in therapy
GB201319620D0 (en) 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Immunosuppressive agents and their use in therapy
US10781431B2 (en) * 2014-04-02 2020-09-22 Marshall University Research Corporation Cardiotonic steroid antagonists and related methods
CN105524139B (zh) 2014-10-17 2020-04-10 上海宝恒泓康生物技术有限公司 高活性的肿瘤抑制剂及其制法和应用
GB201507722D0 (en) 2015-05-06 2015-06-17 Norwegian Univ Sci & Tech Ntnu Anti-bacterial agents and their use in therapy
GB201507721D0 (en) * 2015-05-06 2015-06-17 Norwegian Univ Sci & Tech Ntnu Immunosuppressive agents and their use in therapy
KR20180005249A (ko) 2015-05-19 2018-01-15 예일 유니버시티 병리학적 석회화 병태를 치료하기 위한 조성물, 및 이의 사용 방법
US11390859B2 (en) 2016-08-05 2022-07-19 Yale University Compositions and methods for stroke prevention in pediatric sickle cell anemia patients
IL254361A0 (en) * 2017-09-06 2017-11-30 Nat Inst Biotechnology Negev Ltd Compounds to suppress the methyltransferase setd6
GB202006699D0 (en) 2020-05-06 2020-06-17 Therapim Pty Ltd Dosage regimen
KR102483938B1 (ko) * 2020-06-12 2023-01-04 (주)케어젠 펜타펩타이드를 유효성분으로 포함하는 항알러지 또는 아토피피부염 개선용 조성물
CN112813042B (zh) * 2021-02-08 2021-08-27 南京市妇幼保健院 乳腺脂肪组织来源的多肽及其抗肿瘤应用
WO2024011300A1 (en) * 2022-07-13 2024-01-18 L'oreal Modified peptides, composition, method for inhibiting contraction of muscle cells, method for improving the skin and use of a modified peptide

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5433190A (en) 1989-04-10 1990-11-16 Louisiana State University And Agricultural And Mechanical College Lytic peptides, use for growth, infection and cancer
US5632988A (en) * 1989-10-23 1997-05-27 Schering Corporation Polypeptide inhibitors of gamma interferon
FR2662698A1 (fr) 1990-06-05 1991-12-06 Centre Nat Rech Scient Nouveaux facteurs de croissance neurotropes comprenant un peptide homeoboite.
US5888762A (en) * 1990-06-05 1999-03-30 Centre National De La Recherche Scientifique (Cnrs) Neurotropic growth factors comprising a homeobox peptide
ATE275197T1 (de) * 1991-09-20 2004-09-15 Amgen Inc Glial neurotrophe faktor
US5534110A (en) * 1993-07-30 1996-07-09 Lam Research Corporation Shadow clamp
CA2173611C (en) 1993-10-05 2005-07-26 Paul A. M. Van Leeuwen Method of treating depressed reticuloendothelial system function
GB9422175D0 (en) 1994-11-03 1994-12-21 Univ Dundee Indentification of the p21 waf1-pcna interaction site and therapeutic applications thereof
GB9509557D0 (en) * 1995-05-11 1995-07-05 Univ Dundee PCNA binding substance
FR2739621B1 (fr) * 1995-10-05 1997-12-05 Centre Nat Rech Scient Peptides utilisables comme vecteurs pour l'adressage intracellulaire de molecules actives
ATE374369T1 (de) 1997-03-14 2007-10-15 Crusade Lab Ltd Verfahren zur erkennung von regulatoren des zellzyklus
EP1037911A4 (en) * 1997-12-10 2003-07-23 Univ Washington ANTI-PATHOGEN SYSTEM AND METHOD FOR USE THEREOF
TWI227136B (en) * 1998-05-21 2005-02-01 Smithkline Beecham Corp Novel pharmaceutical composition for the prevention and/or treatment of cancer
US6368831B1 (en) * 1998-06-29 2002-04-09 Childrens Hospital Los Angeles Treatment of hyperproliferative disorders
CN100358529C (zh) 1998-06-29 2008-01-02 洛杉矶儿童医院 全反式视黄酰胺和神经酰胺降解抑制剂的制药用途
GB9814527D0 (en) 1998-07-03 1998-09-02 Cyclacel Ltd Delivery system
US6127177A (en) * 1998-09-11 2000-10-03 Massachusetts Institute Of Technology Controlled reversible poration for preservation of biological materials
JP2002530059A (ja) * 1998-11-13 2002-09-17 サイクラセル・リミテッド 輸送ベクター
AU5322900A (en) 1999-06-04 2000-12-28 Yale University Modulation of protein levels using the scf complex
US6696263B1 (en) 1999-09-23 2004-02-24 Rigel Pharmaceuticals, Inc. PCNA associated cell cycle proteins, compositions and methods of use
CN1297923A (zh) * 1999-11-29 2001-06-06 上海博容基因开发有限公司 一种新的多肽——人含细胞色素c结构域的脂蛋白105和编码这种多肽的多核苷酸
GB9928323D0 (en) 1999-11-30 2000-01-26 Cyclacel Ltd Peptides
CA2395858A1 (en) 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
AU2001238347A1 (en) 2000-02-28 2001-09-12 Hyseq, Inc. Novel nucleic acids and polypeptides
JP4503801B2 (ja) * 2000-09-08 2010-07-14 独立行政法人科学技術振興機構 新規ヒト癌・精巣抗原及びその遺伝子
US6627401B2 (en) * 2000-12-28 2003-09-30 Council Of Scientific And Industrial Research Method for detecting a single nucleotide polymorphism in p21waf1/cip1 gene as an indicator of risk of esophageal cancer
US6875744B2 (en) * 2001-03-28 2005-04-05 Helix Biomedix, Inc. Short bioactive peptides
ES2389285T3 (es) * 2001-03-28 2012-10-24 Helix Biomedix, Inc. Péptidos bioactivos cortos y procedimientos para su uso
US20030114362A1 (en) 2001-06-08 2003-06-19 Novaspin Biotech Gmbh Penta-or tetrapeptide binding to somatostatin receptors and the use of the same
WO2003042239A1 (en) * 2001-11-12 2003-05-22 Stichting Sanquin Bloedvoorziening Peptides inhibiting signaling by ras-like gtpases
AU2002366364A1 (en) 2001-12-18 2003-06-30 Sloan-Kettering Institute For Cancer Research E2f and cancer therapy
US7517857B2 (en) * 2002-01-29 2009-04-14 Posco Immune-modulating peptide
WO2003074003A2 (en) 2002-03-01 2003-09-12 Applied Immune Technologies Immunogens for treatment of neoplastic and infectious disease
JP4221368B2 (ja) * 2002-08-20 2009-02-12 ポリファー リミテッド 抗菌活性を有するテンプレート結合ペプチド擬似体
AU2003294217A1 (en) * 2002-08-29 2004-05-04 Five Prime Therapeutics, Inc. Human polypeptides encoded by polynucleotides and methods of their use
JP2006501820A (ja) * 2002-09-06 2006-01-19 バイエル・フアーマシユーチカルズ・コーポレーシヨン 修飾glp−1受容体アゴニストおよびそれらの薬理学的使用法
US20080199899A1 (en) 2002-10-02 2008-08-21 Etienne Jacotot Method For Screening Modulators of Mitochondrial Functioning and New Modulators Obtained
FR2849603B1 (fr) 2003-01-07 2006-09-08 Centre Nat Rech Scient Composition pour le transport intracellulaire de macromolecules ou particules biologiques
US7772188B2 (en) * 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
FR2855178B1 (fr) * 2003-05-20 2005-08-05 Centre Nat Rech Scient Peptides modulateurs de l'activite du facteur de transcription engrailed
US7772367B2 (en) * 2004-01-30 2010-08-10 The Trustees Of Columbia University In The City Of New York C-terminal p53 palindromic peptide that induces apoptosis of cells with aberrant p53 and uses thereof
AU2005241009A1 (en) * 2004-04-21 2005-11-17 Mcmaster University Myosin light chain kinase inhibitors and their use
GB0410498D0 (en) 2004-05-11 2004-06-16 Cyclacel Ltd Crystal
WO2006005042A2 (en) * 2004-06-30 2006-01-12 Cemines, Inc. Methods and compositions for the diagnosis,prognosis,and treatment of cancer
HUE038099T2 (hu) * 2004-12-21 2018-09-28 Musc Found For Res Dev Kompozíciók és módszerek sebgyógyulás és szöveti regeneráció elõsegítésére
IN2005CH00851A (lt) * 2005-07-04 2008-01-25
US8168748B2 (en) 2005-08-04 2012-05-01 North Carolina State University Peptide aptamers that bind to the rep proteins of ssDNA viruses
JPWO2007049695A1 (ja) * 2005-10-26 2009-04-30 中外製薬株式会社 凝集性glp−1アナログおよび徐放性医薬組成物
BRPI0707948A2 (pt) 2006-02-17 2011-05-17 Univ Indiana Res & Tech Corp inibição baseado em peptìdeo da interação capcna em cáncer
CU23511B6 (es) 2006-02-28 2010-04-13 Biorec B V Combinación farmacéutica para el tratamiento y/o quimiosensibilización de tumores refractarios a drogas anticancerígenas
AU2007264361B2 (en) 2006-06-26 2013-07-18 The University Of British Columbia Secreted Protein Acidic and Rich in Cysteine (SPARC) as chemotherapeutic sensitizers
JP5490714B2 (ja) 2007-11-28 2014-05-14 メディミューン,エルエルシー タンパク質製剤
GB0803352D0 (en) * 2008-02-22 2008-04-02 Ntnu Technology Transfer As Oligopeptidic compounds and uses thereof

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