KR970005177B1 - 담즙산과 그 염을 함유하는 경구용 방출제어 위내성 위약 의약 포뮬레이션 - Google Patents

담즙산과 그 염을 함유하는 경구용 방출제어 위내성 위약 의약 포뮬레이션 Download PDF

Info

Publication number
KR970005177B1
KR970005177B1 KR1019920006053A KR920006053A KR970005177B1 KR 970005177 B1 KR970005177 B1 KR 970005177B1 KR 1019920006053 A KR1019920006053 A KR 1019920006053A KR 920006053 A KR920006053 A KR 920006053A KR 970005177 B1 KR970005177 B1 KR 970005177B1
Authority
KR
South Korea
Prior art keywords
acid
pharmaceutical formulation
tablets
ursodeoxycholic acid
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1019920006053A
Other languages
English (en)
Korean (ko)
Other versions
KR920019360A (ko
Inventor
마치 에지디오
타마그논 지안프랑코
가브리엘 로티니 레온
Original Assignee
알파 와셔만 에스.피.에이
귀도 게라
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 알파 와셔만 에스.피.에이, 귀도 게라 filed Critical 알파 와셔만 에스.피.에이
Publication of KR920019360A publication Critical patent/KR920019360A/ko
Application granted granted Critical
Publication of KR970005177B1 publication Critical patent/KR970005177B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1019920006053A 1991-04-12 1992-04-11 담즙산과 그 염을 함유하는 경구용 방출제어 위내성 위약 의약 포뮬레이션 Expired - Fee Related KR970005177B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000114A/91 1991-04-12
ITBO910114A IT1245891B (it) 1991-04-12 1991-04-12 Formulazioni farmaceutiche a rilascio controllato per uso orale gastroresistenti contenenti acidi biliari e loro sali.

Publications (2)

Publication Number Publication Date
KR920019360A KR920019360A (ko) 1992-11-19
KR970005177B1 true KR970005177B1 (ko) 1997-04-14

Family

ID=11337392

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920006053A Expired - Fee Related KR970005177B1 (ko) 1991-04-12 1992-04-11 담즙산과 그 염을 함유하는 경구용 방출제어 위내성 위약 의약 포뮬레이션

Country Status (9)

Country Link
US (1) US5300300A (enExample)
EP (1) EP0508312B1 (enExample)
JP (1) JP2509046B2 (enExample)
KR (1) KR970005177B1 (enExample)
CA (1) CA2065652C (enExample)
DE (1) DE69213800T2 (enExample)
ES (1) ES2091970T3 (enExample)
IT (1) IT1245891B (enExample)
TW (1) TW215899B (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9212511D0 (en) * 1992-06-12 1992-07-22 Cortecs Ltd Pharmaceutical compositions
IT1255968B (it) * 1992-11-27 1995-11-17 Composizioni farmaceutiche contenenti acido ursodesossicolico
IL109460A (en) * 1993-05-10 1998-03-10 Euro Celtique Sa Controlled release formulation comprising tramadol
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5891471A (en) * 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
US5843480A (en) * 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
DE29717252U1 (de) * 1997-09-26 1998-02-19 Dr. Falk Pharma GmbH, 79108 Freiburg Arzneimittelkit aus einem Budesonid-haltigen und einem Ursodesoxycholsäure-haltigen Arzneimittel zur Behandlung von cholestatischen Lebererkrankungen
JP4790123B2 (ja) 1998-07-24 2011-10-12 ヨー、セオ、ホン 胆汁酸を有する透明水溶液型製剤の調剤
US7772220B2 (en) * 2004-10-15 2010-08-10 Seo Hong Yoo Methods and compositions for reducing toxicity of a pharmaceutical compound
US20050158408A1 (en) * 1998-07-24 2005-07-21 Yoo Seo H. Dried forms of aqueous solubilized bile acid dosage formulation: preparation and uses thereof
US7303768B2 (en) * 1998-07-24 2007-12-04 Seo Hong Yoo Preparation of aqueous clear solution dosage forms with bile acids
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
BR0108080A (pt) * 2000-02-04 2006-02-07 Seo Hong Yoo Preparação de formas de dosagem de solução clara aquosa com ácidos biliares
US6821931B2 (en) * 2002-03-05 2004-11-23 Alpine Mud Products Corporation Water-based drilling fluid additive containing talc and carrier
US20040241252A1 (en) * 2003-05-29 2004-12-02 Abney Christopher Charles Pharmaceutical compositions for oral administration comprising lithium carbonate, processes of making the same, and methods of administering the same
US7145125B2 (en) * 2003-06-23 2006-12-05 Advanced Optical Technologies, Llc Integrating chamber cone light using LED sources
WO2005032549A1 (en) * 2003-09-26 2005-04-14 Smithkline Beecham Corporation Compositions and methods for treatment of fibrosis
US20050181047A1 (en) * 2004-02-18 2005-08-18 Jaime Romero Compositions and methods for timed release of water-soluble nutritional supplements
US7491263B2 (en) * 2004-04-05 2009-02-17 Technology Innovation, Llc Storage assembly
EP1789057B1 (en) * 2004-08-30 2010-02-24 Seo Hong Yoo Neuroprotective effect of solubilized udca in focal ischemic model
EP1809330B1 (en) * 2004-10-15 2011-04-27 Seo Hong Yoo Compositions for reducing toxicity of cisplatin, carboplatin, and oxaliplatin
US20060142241A1 (en) * 2004-11-01 2006-06-29 Yoo Seo H Methods and compositions for reducing neurodegeneration in amyotrophic lateral sclerosis
US20060275364A1 (en) * 2005-05-26 2006-12-07 Ahmed Salah U Flexible Solid Dosage Forms and Methods of Making and Using the Same
LT2124884T (lt) 2006-12-22 2019-08-26 Ironwood Pharmaceuticals, Inc. Tulžies rūgščių sekvestrantus apimančios kompozicijos, skirtos stemplės sutrikimų gydymui
KR101636958B1 (ko) * 2009-09-11 2016-07-06 주식회사 대웅제약 우루소데옥시콜린산-합성하이드로탈사이트-유드라짓 혼성체, 이를 함유하는 약학 조성물 및 그 제조방법
WO2013054285A1 (en) 2011-10-11 2013-04-18 Ranbaxy Laboratories Limited A gastroretentive dosage system and process of preparation thereof
US20170119680A1 (en) 2015-10-30 2017-05-04 R.P. Scherer Technologies, Llc Extended release film-coated capsules
EP4013401A4 (en) 2019-08-12 2023-07-12 Massachusetts Institute of Technology Articles and methods for administration of therapeutic agents
CN118217294B (zh) * 2023-08-08 2024-11-29 成都赛璟生物医药科技有限公司 一种熊去氧胆酸复合物及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2340060A1 (de) * 1973-08-08 1975-02-20 Scherer Gmbh R P Magensaftresistente gelatinekapseln und verfahren zu deren herstellung
IT1101649B (it) 1978-12-15 1985-10-07 Lehner Ag Composizione farmaceutica ad azione prolungata contenente acidi biliari
GB2189699A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated acid-labile medicaments
IT1212141B (it) 1987-06-03 1989-11-08 So Ri Far S R L Composizioni farmaceutiche per la prevenzione e terapia della calcolosi delle vie biliari e della dispepsia biliare.

Also Published As

Publication number Publication date
JP2509046B2 (ja) 1996-06-19
TW215899B (enExample) 1993-11-11
JPH0597677A (ja) 1993-04-20
ES2091970T3 (es) 1996-11-16
ITBO910114A0 (it) 1991-04-12
CA2065652A1 (en) 1992-10-13
IT1245891B (it) 1994-10-25
US5300300A (en) 1994-04-05
DE69213800T2 (de) 1997-02-20
EP0508312B1 (en) 1996-09-18
CA2065652C (en) 1999-01-12
DE69213800D1 (de) 1996-10-24
EP0508312A1 (en) 1992-10-14
KR920019360A (ko) 1992-11-19
ITBO910114A1 (it) 1992-10-12

Similar Documents

Publication Publication Date Title
KR970005177B1 (ko) 담즙산과 그 염을 함유하는 경구용 방출제어 위내성 위약 의약 포뮬레이션
KR970005176B1 (ko) 담즙산을 함유하는 경구용 위내성 의약 포뮬레이션
KR970005175B1 (ko) 담즙산의 염을 함유하는 경구용 위내성 의약 포뮬레이션
KR880001753B1 (ko) 브롬헥신 서방출성 제형의 제조방법
EP1123087B1 (en) Oral pulsed dose drug delivery system
US5316772A (en) Bilayered oral pharmaceutical composition with pH dependent release
AU737121B2 (en) Tramadol multiple unit formulations
JP2005508922A (ja) プロプラノロールの時限徐放性多粒子剤型
BG106605A (bg) Състави с контролирано освобождаване, съдържащи нимесулид
JP2005508922A6 (ja) プロプラノロールの時限徐放性多粒子剤型
SK18832000A3 (sk) Entericky potiahnutá farmaceutická tableta a spôsob jej prípravy
EP2023900B1 (en) Controlled dose drug delivery system
JP2011521977A (ja) 調節放出性ナイアシン処方物
JP3122478B2 (ja) 下部消化管放出型経口製剤
WO2018231619A1 (en) Delayed sustained release pharmaceutical compositions
AU2004200325B2 (en) Oral Pulsed Dose Drug Delivery System
MXPA06004017A (es) Formas de dosis una vez al dia de trospio
AU2006236052A1 (en) Oral pulsed dose drug delivery system
JPS62111919A (ja) プロプラノロ−ル製剤

Legal Events

Date Code Title Description
PA0109 Patent application

St.27 status event code: A-0-1-A10-A12-nap-PA0109

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

G160 Decision to publish patent application
PG1605 Publication of application before grant of patent

St.27 status event code: A-2-2-Q10-Q13-nap-PG1605

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U11-oth-PR1002

Fee payment year number: 1

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 6

FPAY Annual fee payment

Payment date: 20030922

Year of fee payment: 7

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 7

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20040923

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20040923

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000