KR970001370A - 수용액으로부터 알파-l-아스파틸-l-페닐알리닌 메틸 에스테르의 결정화 방법 - Google Patents

수용액으로부터 알파-l-아스파틸-l-페닐알리닌 메틸 에스테르의 결정화 방법

Info

Publication number
KR970001370A
KR970001370A KR1019960027004A KR19960027004A KR970001370A KR 970001370 A KR970001370 A KR 970001370A KR 1019960027004 A KR1019960027004 A KR 1019960027004A KR 19960027004 A KR19960027004 A KR 19960027004A KR 970001370 A KR970001370 A KR 970001370A
Authority
KR
South Korea
Prior art keywords
crystallization
aspartyl
alpha
aqueous solution
methyl ester
Prior art date
Application number
KR1019960027004A
Other languages
English (en)
Other versions
KR100426247B1 (ko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of KR970001370A publication Critical patent/KR970001370A/ko
Application granted granted Critical
Publication of KR100426247B1 publication Critical patent/KR100426247B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1019960027004A 1995-06-30 1996-06-29 수용액으로부터α-L-아스파틸-L-페닐알라닌메틸에스테르의결정화방법 KR100426247B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95201794.5 1995-06-30
EP95201794A EP0751146B1 (en) 1995-06-30 1995-06-30 Crystallization of alpha-L-aspartyl-L-phenylalanine methyl ester from aqueous solution

Publications (2)

Publication Number Publication Date
KR970001370A true KR970001370A (ko) 1997-01-24
KR100426247B1 KR100426247B1 (ko) 2004-06-30

Family

ID=8220443

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019960027004A KR100426247B1 (ko) 1995-06-30 1996-06-29 수용액으로부터α-L-아스파틸-L-페닐알라닌메틸에스테르의결정화방법

Country Status (9)

Country Link
US (1) US5733883A (ko)
EP (1) EP0751146B1 (ko)
KR (1) KR100426247B1 (ko)
CN (1) CN1135237C (ko)
AT (1) ATE214397T1 (ko)
CA (1) CA2180207A1 (ko)
DE (1) DE69525839T2 (ko)
RU (1) RU2155771C2 (ko)
TW (1) TW323270B (ko)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5728862A (en) * 1997-01-29 1998-03-17 The Nutrasweet Company Method for preparing and purifying an N-alkylated aspartame derivative
IL122068A (en) * 1997-10-29 2001-01-28 Yissum Res Dev Co Process for the preparation of crystal form of aspartame
US6657073B1 (en) 1999-08-18 2003-12-02 Daesang Corporation Crystallization of α-L-aspartyl-L-phenylalanine methyl ester
US8956677B2 (en) * 2005-11-23 2015-02-17 The Coca-Cola Company High-potency sweetener composition with glucosamine and compositions sweetened therewith
US20070116822A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-potency sweetener composition with saponin and compositions sweetened therewith
US9144251B2 (en) * 2005-11-23 2015-09-29 The Coca-Cola Company High-potency sweetener composition with mineral and compositions sweetened therewith
CA2629556A1 (en) * 2005-11-23 2007-07-19 The Coca Cola Company Synthetic sweetener compositions with improved temporal profile and/or flavor profile, methods for their formulation, and uses
US20070116825A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Confection with High-Potency Sweetener
US20070134391A1 (en) * 2005-11-23 2007-06-14 The Coca-Cola Company High-Potency Sweetener Composition for Treatment and/or Prevention of Autoimmune Disorders and Compositions Sweetened Therewith
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US8993027B2 (en) * 2005-11-23 2015-03-31 The Coca-Cola Company Natural high-potency tabletop sweetener compositions with improved temporal and/or flavor profile, methods for their formulation, and uses
US20070116831A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Dental Composition with High-Potency Sweetener
US8956678B2 (en) * 2005-11-23 2015-02-17 The Coca-Cola Company High-potency sweetener composition with preservative and compositions sweetened therewith
US20070116836A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition for Treatment and/or Prevention of Osteoporosis and Compositions Sweetened Therewith
US9101161B2 (en) * 2006-11-02 2015-08-11 The Coca-Cola Company High-potency sweetener composition with phytoestrogen and compositions sweetened therewith
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
US20080107787A1 (en) * 2006-11-02 2008-05-08 The Coca-Cola Company Anti-Diabetic Composition with High-Potency Sweetener

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT394854B (de) * 1986-06-12 1992-07-10 Biochemie Gmbh Verfahren zur herstellung von n-l-alpha-aspartyl-l-phenylalanin(nieder)alkylestern
JPH0832719B2 (ja) * 1986-12-19 1996-03-29 三井東圧化学株式会社 吸湿性の小さいα−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの製造法
JP2946853B2 (ja) * 1991-05-09 1999-09-06 味の素株式会社 アスパルテームの晶析法

Also Published As

Publication number Publication date
KR100426247B1 (ko) 2004-06-30
TW323270B (ko) 1997-12-21
CA2180207A1 (en) 1996-12-31
EP0751146B1 (en) 2002-03-13
DE69525839D1 (de) 2002-04-18
RU2155771C2 (ru) 2000-09-10
DE69525839T2 (de) 2002-10-31
EP0751146A1 (en) 1997-01-02
ATE214397T1 (de) 2002-03-15
CN1143649A (zh) 1997-02-26
CN1135237C (zh) 2004-01-21
US5733883A (en) 1998-03-31

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