KR960041357A - 미생물, 이의 용도 및 이를 이용한 L-α-아미노산의 제조방법 - Google Patents

미생물, 이의 용도 및 이를 이용한 L-α-아미노산의 제조방법 Download PDF

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KR960041357A
KR960041357A KR1019960018092A KR19960018092A KR960041357A KR 960041357 A KR960041357 A KR 960041357A KR 1019960018092 A KR1019960018092 A KR 1019960018092A KR 19960018092 A KR19960018092 A KR 19960018092A KR 960041357 A KR960041357 A KR 960041357A
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amino acids
dsm
microorganisms
microorganism
methods
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KR1019960018092A
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바그너 프리츠
한트케 브릿타
바그너 토마스
드라우츠 칼하인츠
봄마리우스 안드레아스
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볼프강 메르크 · 볼프강 베버
데구사 아크티엔게젤샤프트
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Publication of KR960041357A publication Critical patent/KR960041357A/ko

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Abstract

본 발명은 L-α-아미노산의 제조를 위한 신규 미생물, 이의 용도 및 방법에 관한 것이다.
공지된 아쓰로부터 DSM 7329 및 DSM 7330은 유도인자(N3-IMH)가 이용될 때만이 D.L-5-일치환된 하이단토인을 L-α-아미노산으로 전환시키는데 기술적으로 적당한 비활성을 나타낸다.
DSM 9771은 DSM 7330의 돌연변이주이고 선택적 조건하에서 수득된다. 이의 효소 활성은 모균주보다 2.3배 높다. 유도인자 존재하에 상기 활성은 2.7배로 더욱 증가할 수 있다.
증가된 입체학적 특이성과 함께 정량적인 수율로 L-α-아미노산을 수득한다.

Description

미생물, 이의 용도 및 이를 이용한 L-α-아미노산의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. 미생물 DSM 9771.
  2. D-, L- 및/또는 D.L-5-일치환된 하이단토인 및/또는 D-, L- 및/또는 D.L-N-카바모일-α-아미노산을 효소적으로 전환시켜 L-α-아미노산을 제조하는 방법에 있어서, 미생물 DSM 9771 및/또는 이러한 미생물 의해 생산되는 효소를 통해 전환을 수행함을 특징으로 하는 L-α-아미노산의 제조방법.
  3. 제2항에 있어서, 반응을 정지기 미생물로 수행하는 것을 특징으로 하는 방법.
  4. 미생물의 돌연변이주 또는 변이주를 배양하거나, 카바모일라제 및/또는 하이단토인아제 및/또는 하이단토인라세마제를 암호화하는 유전자를 수득하거나, 카바모일라제 및/또는 하이단토인아제 및/또는 하이단토인라세마제를 암호화하는 유전자를 미생물 또는 세포내로 주입하거나, 또는 L-α-아미노산을 제조하기 위한, 미생물 DSM 9771의 용도.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019960018092A 1995-05-30 1996-05-28 미생물, 이의 용도 및 이를 이용한 L-α-아미노산의 제조방법 KR960041357A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19519717A DE19519717C1 (de) 1995-05-30 1995-05-30 Neuer Mikroorganismus, dessen Verwendung und Verfahren zur Herstellung von L-alpha-Aminosäuren
DE19519717.8 1995-05-30

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KR960041357A true KR960041357A (ko) 1996-12-19

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ID=7763170

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US (1) US5714355A (ko)
EP (1) EP0745678B1 (ko)
JP (1) JP3905575B2 (ko)
KR (1) KR960041357A (ko)
DE (2) DE19519717C1 (ko)
SG (1) SG60001A1 (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11508452A (ja) * 1995-07-11 1999-07-27 デグッサ アクチエンゲゼルシャフト ペプチドおよびｎ−カルバモイル保護されたペプチドの新規製造法
US6524837B1 (en) * 1999-03-29 2003-02-25 California Institute Of Technology Hydantoinase variants with improved properties and their use for the production of amino acids
CA2385241A1 (en) * 1999-09-17 2001-03-22 Sa Bioproducts (Proprietary) Limited Micro-organisms, their use and method for producing d-amino acids
US6713288B1 (en) 1999-09-28 2004-03-30 University Of Stuttgart Whole cell catalysts
ATE512217T1 (de) 2000-09-13 2011-06-15 Ajinomoto Kk 5-substituerte hydantoin racemase, dafür kodierende dna, und verfahren zur herstellung optisch aktiver aminosäure
DE10050124A1 (de) 2000-10-11 2002-04-25 Degussa Verwendung der Acetylaminosäureracemase aus Amycolatopsis orientalis Racemisierung von Carbamoylaminosäuren
WO2002081626A2 (en) 2001-04-03 2002-10-17 Bristol-Myers Squibb Company D-hydantoinase from ochrobactrum anthropi
NL1019416C2 (nl) * 2001-11-23 2003-06-02 Dsm Nv Werkwijze voor het bereiden van een enantiomeer verrijkt a-aminozuur.
EP1656454A4 (en) * 2003-07-08 2011-06-22 Novus Int Inc PROCESS FOR METHIONINAL RECOVERY
EP3229807A4 (en) 2014-12-11 2018-10-17 President and Fellows of Harvard College Inhibitors of cellular necrosis and related methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52125692A (en) * 1976-02-04 1977-10-21 Kanegafuchi Chem Ind Co Ltd Preparation of l-methionine
DK164923C (da) * 1984-04-11 1993-01-25 Denki Kagaku Kogyo Kk Fremgangsmaade til fremstilling af l-alfa-aminosyrer
EP0377083B1 (de) * 1989-01-02 1993-09-22 Rütgerswerke Aktiengesellschaft Verfahren zur Herstellung von L-alpha-Aminosäuren
DE4316928C2 (de) * 1993-05-19 1995-03-16 Degussa Neue Mikroorganismen, deren Verwendung und Verfahren zur Herstellung von L-alpha-Aminosäuren

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JPH08322557A (ja) 1996-12-10
EP0745678B1 (de) 2001-03-14
SG60001A1 (en) 1999-02-22
DE59606567D1 (de) 2001-04-19
DE19519717C1 (de) 1996-08-22
EP0745678A3 (de) 1998-03-04
US5714355A (en) 1998-02-03
EP0745678A2 (de) 1996-12-04
JP3905575B2 (ja) 2007-04-18

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