KR960031984A - 개선된 미량 유기 분석체의 고상 미소추출 - Google Patents

개선된 미량 유기 분석체의 고상 미소추출 Download PDF

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KR960031984A
KR960031984A KR1019960004289A KR19960004289A KR960031984A KR 960031984 A KR960031984 A KR 960031984A KR 1019960004289 A KR1019960004289 A KR 1019960004289A KR 19960004289 A KR19960004289 A KR 19960004289A KR 960031984 A KR960031984 A KR 960031984A
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organic solvent
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씨-피. 셔먼 히수
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죠애니 레비
말린크롯트 베이커 인크.
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    • G01N1/00—Sampling; Preparing specimens for investigation
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/405—Concentrating samples by adsorption or absorption
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    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4055—Concentrating samples by solubility techniques
    • G01N2001/4061—Solvent extraction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N2030/009—Extraction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/16—Phosphorus containing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
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    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/19—Halogen containing
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/21—Hydrocarbon
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/21—Hydrocarbon
    • Y10T436/212—Aromatic

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Abstract

본 발명의 검출 대상의 미량 유기 분석체, 특히 유기 용매 캐리어 매트릭스에 의해 샘플로부터 추출가능한 반휘발성의 유기분석체를 추출하고, SPME에 의해 상기 미량 유기 분석체의 분석을 행함에 있어 검출감도를 향상시키는 방법에 관한 것으로, 이때 그 기술적 특징은 SPME 파이퍼 추출 및 미량 유기 분석체의 검출을 수행하기 전에 유기용매 분석체를 함유하는 액상 캐리어 매트릭스를 액상 캐리어 매트릭스로 교체시키는데 있다.

Description

개선된 미량 유기 분석체의 고상 미소추출
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 SPME방법에 의해 유기용매(핵산) 캐리어 매트릭스내의 미량 유기살충제 분석체의 검출을 위한 시도에 대한 크로마토그램.

Claims (9)

  1. 유기용매 캐리어 매트릭스내로 추출되거나 용해되어 검출대상으로 되는 미량 유기분석체의 검출방법으로서, 상기 유기용매 캐리어 매트릭스내에서 미량 유기 분석체를 선택적으로 농축한 다음, 고상 미소추출 장치의 파이버상에 미량 유기 분석체를 흡착하고, 이어서 상기 파이버로부터 미량 유기 분석체를 탈착시켜 하나 또는 그 이상의 유기 분석체의 검출을 위한 분석장치내로 이송시키는 일련의 공정으로 이루어지며, 이 때 파이버상에 미량 유기 분석체를 흡착하기 전에 미량 유기분석체를 함유하는 유기용매 캐리어 매트릭스에 물을 가하여 혼합물을 얻은 다음 상기 혼합물로부터 유기용매 캐리어 매트릭스를 제거하여 상기 파이버상에 위치하는 미량 유기분석체의 탈착을 위해서 액상 캐리어 매트릭스내에서 미량 유기 분석체의 검출샘플을 얻는 것을 특징으로 하는 미량 유기 분석체의 검출방법.
  2. 제1항에 있어서, 환경샘플중의 미량 유기 분석체를 검출하는 방법이; (1)미량 유기 분석체를 함유하는 검출대상의 환경샘플을 마련하고, (2)상기 환경샘플이 유기용매 캐리어 매트릭스를 포함하고 있지 않을 경우, 상기 환경샘플로부터의 어떠한 미량의 유기 분석체를 그러한 미량 유기 분석체의 용해가 가능한 유기용매 캐리어 매트릭스내로 함입시켜 유기용매의 추출을 행하며, (3)상기 유기용매만을 제거함으로써 유기용매 캐리어 매트릭스내의 미량 유기용매 분석체를 선택적으로 농축하고, (4)그 다음, 물을 가함으로써 테스트 샘플의 유기용매 캐리어를 교체시켜 혼합물을 형성함과 아울러 상기 유기용매 캐리어 매트릭스를 제거하여 미량 유기분석체를 함유하는 액상 매트릭스로 구성된 검출샘플을 얻고, 이어서, 다음과 같은 공정을 통해서 상기 검출샘플상에 고상 미소추출을 수행하는 바, 그 공정은, (5)고상 미소추출 장치의 파이버를 상기 액상 캐리어 매트릭스나 액상 캐리어 매트릭스 위쪽의 제한된 상부공간에 미량 유기 분석체의 추출에 충분한 시간에 걸쳐 접촉하도록 위치시킴으로써 유기 분석체가 액상 캐리어 매트릭스로부터 파이버위로 흡착이 일어나도록 하며, (6)후속 공정으로서 액상 캐리어 매트릭스나 제한된 상부공간으로부터 파이어를 분리하고 파이버위의 유기 분석체를 탈착시켜 하나 또는 그 이상의 미량 유기 분석체의 분석을 위한 분석장치내로 이송시키고, (7)상기 분석장치에서 하나 또는 그 이상의 유기 분석체를 검출하는 것을 특징으로 하는 미량 유기 분석체의 검출방법.
  3. 제1항 또는 제2항에 있어서, 미량 유기 분석체가 유기 용매의 비등점 이상의 적어도 25℃의 비등점을 갖는 반휘발성 유기 분석체인 것을 특징으로 하는 미량 유기 분석체의 검출방법.
  4. 제1항 또는 제2항에 있어서, 미량 유기 분석체가 유기용매의 비등점 이상의 적어도 50℃의 비등점을 갖는 반휘발성 유기 분석체인 것을 특징으로 하는 미량 유기 분석체의 검출방법.
  5. 제4항에 있어서, 미량 유기 분석체는 살충제, 제초제, 폴리클로리네이티드 바이페닐 화합물 및 폴리뉴클리어 어로마틱 하이드로카본 화합물로 이루어진 군으로부터 선택되는 것을 특징으로 하는 미량 유기 분석체의 검출방법.
  6. 제1항 또는 제2항에 있어서, 환경샘플로부터의 미량 유기 분석체의 추출은 유기용매를 이용한 액-액 또는 액-고 추출에 의해서 수행되는 것을 특징으로 하는 미량 유기 분석체의 검출방법.
  7. 제1항 내지 제5항중 어느 한 항에 있어서, 상기 방법은 ppt(part per trilion)의 검출레벨로 유기분석체에 대한 검출을 가능하게 하는 것을 특징으로 하는 미량 유기 분석체의 검출방법.
  8. 제1항 내지 제5항중 어느 한 항에 있어서, 상기 방법은 서브-ppt(sub-ppt)의 검출레벨로 유기분석체에 대한 검출을 가능하게 하는 것을 특징으로 하는 미량 유기 분석체의 검출방법.
  9. 제1항 내지 제8항 중 어느 한 항에 있어서, 유기용매는 유기용매의 증발에 의해서 혼합물로부터 제거됨을 특징으로 하는 미량 유기 분석체의 검출방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019960004289A 1995-02-28 1996-02-23 개선된 미량 유기 분석체의 고상 미소추출 KR100202966B1 (ko)

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US08/396,124 US5576217A (en) 1995-02-28 1995-02-28 Solid phase microextraction of trace amounts of organic analytes
US8/396,124 1995-02-28
US08/396,124 1995-02-28

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US (1) US5576217A (ko)
EP (1) EP0730143B1 (ko)
JP (1) JP2867237B2 (ko)
KR (1) KR100202966B1 (ko)
AT (1) ATE285071T1 (ko)
AU (1) AU696672B2 (ko)
CA (1) CA2169104C (ko)
DE (1) DE69634022T2 (ko)
IL (1) IL117207A (ko)
NZ (1) NZ286077A (ko)

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CN109030657A (zh) * 2018-08-27 2018-12-18 广州风行乳业股份有限公司 一种动物奶中硫丹农药残留的检测方法
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CN110068626A (zh) * 2019-05-08 2019-07-30 东莞市信准检测技术服务有限公司 儿童玩具中邻苯二甲酸酯的测定方法
CN111665300A (zh) * 2020-05-21 2020-09-15 国网河北省电力有限公司电力科学研究院 同时测定土壤中多环芳烃和多氯联苯的方法
CN112305131B (zh) * 2020-11-24 2021-09-21 中国农业科学院农业质量标准与检测技术研究所 一种动物源性食品中农药残留的GC-Orbitrap-MS筛查分析方法
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DE69634022D1 (de) 2005-01-20
US5576217A (en) 1996-11-19
JPH08261999A (ja) 1996-10-11
EP0730143A3 (ko) 1996-09-18
ATE285071T1 (de) 2005-01-15
NZ286077A (en) 1996-11-26
EP0730143B1 (en) 2004-12-15
DE69634022T2 (de) 2005-12-08
IL117207A (en) 1998-02-22
JP2867237B2 (ja) 1999-03-08
CA2169104A1 (en) 1996-08-29
EP0730143A2 (en) 1996-09-04
IL117207A0 (en) 1996-06-18
AU696672B2 (en) 1998-09-17
KR100202966B1 (ko) 1999-06-15

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