KR960017654A - 3-0-치환 아스코르빈산의 제조방법 - Google Patents

3-0-치환 아스코르빈산의 제조방법 Download PDF

Info

Publication number
KR960017654A
KR960017654A KR1019950002257A KR19950002257A KR960017654A KR 960017654 A KR960017654 A KR 960017654A KR 1019950002257 A KR1019950002257 A KR 1019950002257A KR 19950002257 A KR19950002257 A KR 19950002257A KR 960017654 A KR960017654 A KR 960017654A
Authority
KR
South Korea
Prior art keywords
group
ascorbic acid
general formula
aqueous solvent
following general
Prior art date
Application number
KR1019950002257A
Other languages
English (en)
Other versions
KR100346672B1 (ko
Inventor
야스노리 니이로
히로끼 우에다
Original Assignee
미끼 도꾸따로
가부시끼가이샤 닛뽕하이폭스
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 미끼 도꾸따로, 가부시끼가이샤 닛뽕하이폭스 filed Critical 미끼 도꾸따로
Publication of KR960017654A publication Critical patent/KR960017654A/ko
Application granted granted Critical
Publication of KR100346672B1 publication Critical patent/KR100346672B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/62—Three oxygen atoms, e.g. ascorbic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Furan Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

수용성의 3-0-치환 아스코르빈산을 간편하게 고수율로 제조하는 방법을 제공한다.
하기 일반식(Ⅰ)로 표시되는 3-0-치환-5,6-이소프로필리덴아스코르빈산을 비수성 용매중 산성이온 교환수지로 처리하여 상기 일반식(Ⅰ)으로 표시되는 화합물중의 디옥소란 고리를 개환하고, vic-글리콜 기를 형성하는 것을 특징으로 하는 하기 일반식(Ⅱ)로 표시되는 3-0-치환 아스코르빈산의 제조방법.
(식중 R은 저급알킬기 및 저급알킬카르보닐 저급알킬기로 이루어진 군으로부터 선택된 기이다)

Description

3-0-치환 아스코르빈산의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (5)

  1. 하기 일반식(Ⅰ)로 표시되는 3-0-치환-5,6-0-이소프로필리덴 아스코르빈산을 비수성 용매중, 산성이온 교환수지로 처리하여 하기 일반식(Ⅰ)로 표시되는 화합물중의 디옥소란 고리를 개환하고, vic-글리콜기를 형성하는 것을 특징으로 하는 하기 일반식(Ⅱ)로 표시되는 3-0-치환 아스코르빈산의 제조방법.
    〔식중, R은 저급 알킬기 및 저급알킬카르보닐 저급알킬기로 이루어진 군으로부터 선택된 기이다.〕
  2. 제1항에 있어서, 비수성 용매가 제1급 알콜류, 에테르류 및 할로겐화 탄화수소류로 이루어진 군으로부터 선택되는 1종 이상인 방법.
  3. 제1항에 있어서, 비수성 용매가 에스테르류, 니트릴류, 방향족 탄화수소류, 지방족 탄화수소류 및 비프로로톤성 유기용매로 이루어진 군으로부터 선택되는 1종 이상인 방법.
  4. 제1항에 있어서, 비수성 용매가 제1급 알콜류, 에테르류 및 할로겐화 탄화수소류로 이루어진 군으로부터 선택되는 1종 이상과, 에스테르류, 니트릴류, 방향족 탄화수소류, 지방족 탄화수소류 및 비프로톤성 유기용매로 이루어진 군으로 부터 선택되는 1종 이상과의 혼합물인 방법.
  5. 제1항에 있어서, 산성 이온 교환수지가 유효 관능기로서 슬폰 산기 또는 카르복실산기를 갖는 것인 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019950002257A 1994-11-08 1995-02-08 3-o-치환 아스코르브산의 제조방법 KR100346672B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6273527A JPH08134055A (ja) 1994-11-08 1994-11-08 ３−ｏ−置換アスコルビン酸の製造方法
JP94-273527 1994-11-08

Publications (2)

Publication Number Publication Date
KR960017654A true KR960017654A (ko) 1996-06-17
KR100346672B1 KR100346672B1 (ko) 2002-11-23

Family

ID=17529098

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950002257A KR100346672B1 (ko) 1994-11-08 1995-02-08 3-o-치환 아스코르브산의 제조방법

Country Status (2)

Country Link
JP (1) JPH08134055A (ko)
KR (1) KR100346672B1 (ko)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002284665A (ja) * 2001-03-23 2002-10-03 Nippon Hypox Lab Inc 化粧料
JP2002284625A (ja) * 2001-03-23 2002-10-03 Nippon Hypox Lab Inc 化粧料
JP2002284626A (ja) * 2001-03-23 2002-10-03 Nippon Hypox Lab Inc 皮膚外用剤
KR100500503B1 (ko) * 2001-05-30 2005-07-14 (주)코스몰 결정성 3-0-알킬아스코르빈산의 제조방법
US6861050B2 (en) 2001-06-08 2005-03-01 Shiseido Company, Ltd. Method of preventing darkening of skin or inhibiting melanization of melenin monomer and polymerization inhibitor of biological dihydroxyindole compound
KR100459679B1 (ko) * 2003-04-30 2004-12-03 주식회사 펩트론 펩타이드가 결합된 비타민 씨 유도체, 이의 제조방법 및이를 포함하는 조성물
KR100761959B1 (ko) * 2006-10-12 2007-10-04 (주)코스몰 결정성 3-ｏ-치환된 아스코르빈산의 제조방법
KR101350540B1 (ko) 2012-02-01 2014-01-14 주식회사 카이로켐 엘-3-오-알킬 아스코르빈산의 제조방법
CN105367524A (zh) * 2015-06-19 2016-03-02 上海珈叶实业有限公司 3-o-烷基抗坏血酸的制备方法
CN110642816A (zh) * 2019-09-25 2020-01-03 旖肽(上海)生物科技有限公司 结晶型3-o-乙基维生素c及其制备方法和应用
JPWO2022059776A1 (ko) 2020-09-17 2022-03-24
CN116322705A (zh) 2020-09-17 2023-06-23 株式会社力森诺科 自噬激活剂
KR20230145931A (ko) * 2022-04-11 2023-10-18 한국과학기술원 사이클로헥센 유도체의 개환 복분해 중합반응을 통한 화학적 리사이클링이 가능한 폴리비닐알코올 공중합체의 제조방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6377890A (ja) * 1986-09-19 1988-04-08 Nippon Saafuakutanto Kogyo Kk Ｌ−アスコルビン酸−２−リン酸エステルの精製法
JP2830268B2 (ja) * 1989-01-21 1998-12-02 武田薬品工業株式会社 アスコルビン酸誘導体の製造法
US5143648A (en) * 1989-07-20 1992-09-01 Nippon Hypox Laboratories Incorporated Ascorbic acid derivative and use as antioxidant
JPH06263790A (ja) * 1993-03-12 1994-09-20 Unitika Ltd ２−Ｏ−β−Ｄ−ガラクトピラノシル−Ｌ−アスコルビン酸またはその塩およびその製造法並びにその用途

Also Published As

Publication number Publication date
KR100346672B1 (ko) 2002-11-23
JPH08134055A (ja) 1996-05-28

Similar Documents

Publication Publication Date Title
KR960017654A (ko) 3-0-치환 아스코르빈산의 제조방법
GB1129005A (en) Solubilised polymers
JPS612707B2 (ko)
FI802123A (fi) Foerfarande foer behandling av oxider av saellsynta jordmetaller och gallium
ATE119893T1 (de) Herstellung von monoepoxiden.
ATE128110T1 (de) Verfahren zur herstellung von vinylethern.
BG104302A (en) Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids
FR2396019A1 (fr) Nouveaux glycopeptides acetyles hydrosolubles extraits de corps microbiens lyses de pseudomonas aeruginosa, procede de preparation et application a titre de medicaments
ES2196551T3 (es) Compuestos y procedimiento para la preparacion de acidos 4-fenil-4-cianociclohexanoicos sustituidos.
JPS53111393A (en) Preparation of alkyd resin for water dispersion
JPS5777670A (en) Preparation of 2-azetidinone derivative
JPS5235179A (en) Recovering method of organic solvent
JPS5422305A (en) Isolation of glycols
DE69503106D1 (de) Verfahren zur Herstellung von L-Ascorbinsäure
JPS55100342A (en) Preparation of nitrodiarylamine
EP0995736A3 (en) Method for recovering fluorine-containing solvents
KR830004304A (ko) 마이코프라네신 유도체의 제조방법
JPS5412369A (en) Preparation of thienylacetic acid
JPS53144543A (en) Improved method of producing cylcohexane derivative
RU95105585A (ru) Способ получения амидов 3,3-диарилакриловой кислоты
KR840004061A (ko) 2-디에틸아미노-1-메틸에틸시스-1-히드록시-(비시클로헥실)-2-카르복실산염 유도체의 제조방법
JPS5214731A (en) Process for preparation of 4-nitro-3-substituted or unsubstituted-n-al kylanilines
ES8106750A1 (es) Procedimiento para la obtencion de soluciones concentradas de colorantes complejos.
JPS51138660A (en) Process for prep aration of polycyclic urethanes
KR910004644A (ko) 2-데옥시-2,2-디플루오로자일로스 유사체 및 그의 중간체의 제조방법

Legal Events

Date Code Title Description
A201 Request for examination
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 20120611

Year of fee payment: 11

FPAY Annual fee payment

Payment date: 20130520

Year of fee payment: 12

LAPS Lapse due to unpaid annual fee